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Full-Text Articles in Engineering
Electrospinning Nanofibers From Chitosan-Hyaluronic Acid Complex Coacervates, Juanfeng Sun
Electrospinning Nanofibers From Chitosan-Hyaluronic Acid Complex Coacervates, Juanfeng Sun
Masters Theses
Electrospun nanofibers have been used for many applications, but a reliance on organic solvents limits their use in biomedical fields. In this study, we successfully electrospun nanofibers from aqueous chitosan-hyaluronic acid complex coacervates. We studied how solvent’ properties affected the average nanofiber diameter by using pure water as a solvent versus ethanol-water solutions. Experimentally, we investigated the effect of electrospinning apparatus parameters, such as how the applied voltage affected fiber formation and morphology. The smallest average nanofiber diameter was determined to be around 115 ± 30 nm when 3 wt% ethanol coacervate samples were electrospun using the applied voltage of …
Synthesis Of Biopolymer Materials Tailored For Biological Applications, Nathan P. Birch
Synthesis Of Biopolymer Materials Tailored For Biological Applications, Nathan P. Birch
Doctoral Dissertations
Biopolymers are able to address a wide variety of medical concerns from chronic wounds to stem cell cultivation to antibacterial and antifouling applications. They are non-toxic, biodegradable, and biocompatible, making them ideal candidates for creating green materials for biological applications. In this thesis, we cover the synthesis of two novel materials from the biopolymers, chitosan and pectin. Chitosan is a biocompatible antibacterial polycation and pectin is an anti-inflammatory polyanion with a strong propensity for hydrogen-bonding. The two chitosan:pectin materials, particles and hydrogels, explore some of the structures that can be created by tuning the electrostatic interactions between chitosan and pectin. …
Polyelectrolyte-Functionalized Nanofiber Mats Control The Collection And Inactivation Of Escherichia Coli, Katrina A. Rieger, Michael Porter, Jessica D. Schiffman
Polyelectrolyte-Functionalized Nanofiber Mats Control The Collection And Inactivation Of Escherichia Coli, Katrina A. Rieger, Michael Porter, Jessica D. Schiffman
Chemical Engineering Faculty Publication Series
Quantifying the effect that nanofiber mat chemistry and hydrophilicity have on microorganism collection and inactivation is critical in biomedical applications. In this study, the collection and inactivation of Escherichia coli K12 was examined using cellulose nanofiber mats that were surface-functionalized using three polyelectrolytes: poly (acrylic acid) (PAA), chitosan (CS), and polydiallyldimethylammonium chloride (pDADMAC). The polyelectrolyte functionalized nanofiber mats retained the cylindrical morphology and average fiber diameter (~0.84 µm) of the underlying cellulose nanofibers. X-ray photoelectron spectroscopy (XPS) and contact angle measurements confirmed the presence of polycations or polyanions on the surface of the nanofiber mats. Both the control cellulose and …