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Quantitative Assessment Of Brain Iron Content As A Function Of Age Using Magnetic Resonance Imaging, Kiarash Ghassaban
Quantitative Assessment Of Brain Iron Content As A Function Of Age Using Magnetic Resonance Imaging, Kiarash Ghassaban
Wayne State University Theses
As the most abundant transition metal in the brain, iron is known to play a key role in a variety of functional and cellular processes. Recent in vivo and post-mortem studies have shown that the levels of iron deposition in the brain, particularly in deep gray matter nuclei, vary as a function of age. On the other hand, elevated iron has also been associated with some neurodegenerative diseases such as Multiple Sclerosis (MS) and Parkinson’s disease (PD) among others.
Magnetic Resonance Imaging (MRI) is a widely used non-invasive and non-ionizing imaging modality which is sensitive to magnetic properties of materials …