Engineering Commons^™

Quantitative Assessment Of Brain Iron Content As A Function Of Age Using Magnetic Resonance Imaging, Kiarash Ghassaban

Wayne State University Theses

As the most abundant transition metal in the brain, iron is known to play a key role in a variety of functional and cellular processes. Recent in vivo and post-mortem studies have shown that the levels of iron deposition in the brain, particularly in deep gray matter nuclei, vary as a function of age. On the other hand, elevated iron has also been associated with some neurodegenerative diseases such as Multiple Sclerosis (MS) and Parkinson’s disease (PD) among others.

Magnetic Resonance Imaging (MRI) is a widely used non-invasive and non-ionizing imaging modality which is sensitive to magnetic properties of materials …

Compressed Sensing And Joint Acquisition Techniques In Mri, Rouhollah Hamtaei

Wayne State University Theses

The relatively long scan times in Magnetic Resonance Imaging (MRI) limits some clinical applications and the ability to collect more information in a reasonable period of time. Practically, 3D imaging requires longer acquisitions which can lead to a reduction in image quality due to motion artifacts, patient discomfort, increased costs to the healthcare system and loss of profit to the imaging center. The emphasis in reducing scan time has been to a large degree through using limited k-space data acquisition and special reconstruction techniques. Among these approaches are data extrapolation methods such as "constrained reconstruction" techniques, data interpolation methods such …