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Theses and Dissertations

Mississippi State University

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Metabolic Profiling Of Firefighter Plasma Using 1h Nmr Platform Following Curcumin, Ketone Supplementations And Carbohydrate Restricted Diet Benefits For Oxidative Stress Suppression, Richard Eugene Baird May 2022

Metabolic Profiling Of Firefighter Plasma Using 1h Nmr Platform Following Curcumin, Ketone Supplementations And Carbohydrate Restricted Diet Benefits For Oxidative Stress Suppression, Richard Eugene Baird

Theses and Dissertations

Occupational health surveys reported that first responders such as firefighters (FF) have some of the highest levels of cardiovascular disease in the nation from poor eating habits and lack of exercise. Three studies were established with goals to identify oxidative stress (OS) biomarkers and improve cardiovascular health for FF including: 1) a 28-day-carbohydrate restricted diet (CRD), 2) a heat-house search and clear protocol in personal protection equipment (PPE) plus curcumin supplementation, and 3) a treadmill exercise protocol in PPE with ketone salt supplementation. During those studies, stored blood plasma subsamples were evaluated for targeted antioxidants or untargeted metabolite concentration fluctuations …