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An Examination Of Acute Cross-Over Effects Following Unilateral Low Intensity Concentric And Eccentric Exercise, William Miller, Sunggun Jeon, Xin Ye Sep 2020

An Examination Of Acute Cross-Over Effects Following Unilateral Low Intensity Concentric And Eccentric Exercise, William Miller, Sunggun Jeon, Xin Ye

Faculty and Student Publications

We compared the effects of low intensity concentric (CON) and eccentric (ECC) exercise on the force and neural responses of the dominant (exercised) elbow flexors (EFs), and studied if these conditions could induce cross-over effects to the contralateral (non-exercised) EFs. Fifteen subjects (8 males) completed all conditions (CON and ECC: 6 sets of low intensity exercise to failure; control: rest) in separate visits with a randomized order. Maximal isometric force and electromyography (EMG) of the dominant and contralateral EFs were assessed at pre, immediate-, 24-, and 48-h-post. Two-factor (condition and time) linear mixed-model analyses were performed to examine the force …


Ubiquitin Proteasome System Activity Is Suppressed By Curcumin Following Exercise-Induced Muscle Damage In Human Skeletal Muscle, Thomas D. Cardaci, Steven B. Machek, Dylan T. Wilburn, Paul S. Hwang, Darryn Willoughby Phd Feb 2020

Ubiquitin Proteasome System Activity Is Suppressed By Curcumin Following Exercise-Induced Muscle Damage In Human Skeletal Muscle, Thomas D. Cardaci, Steven B. Machek, Dylan T. Wilburn, Paul S. Hwang, Darryn Willoughby Phd

International Journal of Exercise Science: Conference Proceedings

PURPOSE: Curcumin is a natural polyphenolic compound with antioxidant and anti-inflammatory properties. In vitro and in vivo animal studies have demonstrated that exposure to curcumin leads to dysregulation of the ubiquitin-proteasome system (UPS). However, to date, no study has investigated curcumin’s ability to influence UPS activity in a human model. Therefore, the purpose of this study was to investigate the effects of curcumin supplementation on markers of UPS activity in the presence of elevations in UPS activity due to exercise-induced muscle damage. METHODS: Twenty-three recreationally active male and female participants between the ages of 18-30 were randomized into …