American Studies Commons^™

The Role Of Lipoproteins/Cholesterol In Genomic Instability And Chromosome Mis-Segregation In Alzheimer's And Cardiovascular Disease, Antoneta Granic

USF Tampa Graduate Theses and Dissertations

Several lines of evidence link Alzheimer's disease (AD) to atherosclerosis (CVD), including that elevated low density lipoprotein (LDL)-cholesterol is a common risk factor. Development of genomic instability could also link the two diseases. Previous fluorescence in situ hybridization (FISH) analyses revealed a clonal expansion of aneuploid smooth muscle cells underlying atherosclerotic plaques. Likewise, cellular and mouse models of AD revealed tau-dependent mitotic defects and subsequent aneuploidy partly resulting from amyloid-beta (A&beta) interference with microtubule (MT) stability, and specific MT motors function. Moreover, AD patients develop aneuploid/hyperploid cells in brain and peripheral tissues, implicating similar mechanism that may lead to apoptosis …

Relationship Between Cancer-Related Fatigue And Depression: A Pilot Study, Gloria Michelle Guess

USF Tampa Graduate Theses and Dissertations

Fatigue is one of the most bothersome symptoms reported by patients diagnosed with cancer, and research indicates that the majority of patients receiving chemotherapy report symptoms of fatigue. Fatigue can have an effect on quality of life; therefore, it is essential that healthcare providers gain a better understanding and recognition of fatigue.

Fatigue can also be a symptom of depression. Depression is another prominent symptom reported by patients diagnosed with cancer. Unfortunately, there are similarities between the symptoms of depression and fatigue making it difficult for health care providers to distinguish between the two. This study utilizes the subscale of …

A Comparison Of Oncology And Non-Oncology Nurses In Their Knowledge Of Cancer Pain Management, Nicole Houle

USF Tampa Graduate Theses and Dissertations

Approximately 1.5 million people are diagnosed with cancer each year. Most of these people will experience pain at some point during or after their treatment. Areas of knowledge that nurses have been shown to have deficits in include assessment and pharmacological management. These types of issues can affect the treatment given to their patients. The purpose of this study is to evaluate the level of knowledge of cancer pain management in oncology and non-oncology nurses and how they compare with each other.

To study these variables, two instruments, the Pain Management Knowledge Test and a demographic survey, were distributed to …

Friendship Networks, Perceived Reciprocity Of Support, And Depression, Ryan Francis Huff

USF Tampa Graduate Theses and Dissertations

Using social network analysis as a theoretical framework, the current study examined the associations between self-reported egocentric network characteristics and depression among a sample of United States college students. It is important to understand factors related to depression among this population due to the severity of its potential outcomes (e.g., suicide and interpersonal problems at school). Drawing inspiration from a recent study conducted by Christina Falci and Clea McNeely (2009), the current investigation used OLS regression to test for both linear and curvilinear relationships between egocentric network size and depression. Potential interactions between network size, density, and gender were also …

Case-Control Study Of Sunlight Exposure And Cutaneous Human Papillomavirus Seroreactivity In Basal Cell And Squamous Cell Carcinomas Of The Skin, Michelle R. Iannacone

USF Tampa Graduate Theses and Dissertations

Non-melanoma skin cancer (NMSC), comprised of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), is the most common cancer in Caucasians. Ultraviolet radiation (UVR) exposure is the most important environmental risk factor for both BCC and SCC development. However, the precise relationship between UVR and the risk of NMSC is complex, and the relationship may differ by skin cancer type. It has been hypothesized that intermittent patterns and childhood sunlight exposure are important for BCC while continuous (chronic) and lifelong (i.e. childhood and adulthood) sunlight exposure is important for SCC. Epidemiologic studies have demonstrated that cutaneous human papillomavirus (HPV) …

Evaluating Knowledge And Attitudes Of Graduate Nursing Students Regarding Pain, Eric Bartholomew Jackson

USF Tampa Graduate Theses and Dissertations

Insufficient pain management continues to be problematic for hospitalized patients throughout the country. It significantly interferes with a person's quality of life making it an issue of great concern to nurses in any setting. However, nurses do not do a good job of managing pain. The purpose of this evaluation was to assess graduate nursing students' knowledge and attitudes toward pain management.

Forty (n=40) graduate nursing students were asked to participate in the evaluation. All students agreed and completed the Demographic Data Form, Nurses Attitude Survey and the Pain Management and Principles Assessment. Thirty-eight females and two males participated in …

Impact Of A Wellness Clinic Visit On Cardiovascular Risk Biomarkers In Employees Of A Va Medical Center, Margaret Asomaning

USF Tampa Graduate Theses and Dissertations

Background: Worksite screening programs are increasingly being provided by employers as a means to reduce cardiovascular risk in employees. A screening program that consists of fasting serum analysis of glucose plus a lipid panel is offered yearly to employees at the VA medical center in Tampa. A retrospective study was conducted to determine if a wellness clinic exposure resulted in significant changes in employees' markers of cardiovascular risk.

Methods: Computerized records were used to follow serial outcomes for glucose, triglycerides, HDL cholesterol, and LDL cholesterol in employees whose screening results showed abnormal levels of one or more of …

Validation Of The Usf Safe Exposure Time Equation For Heat Stress, Arden Bruce Andersen

USF Tampa Graduate Theses and Dissertations

Heat stress conditions are prevalent in the working environment around the world. Often they are not readily engineered out. Administrative controls and, in extreme/toxic environments, personal protective gear are the means available to protect workers. For every combination of metabolic work rate, clothing ensemble and environmental WBGT, there is a time of exposure threshold, beyond which the worker can no longer compensate for the heat stress, and signs and symptoms of heat strain appear. Increasingly, worker environments require specialty clothing either for worker protection or to maintain a clean/sanitary environment. Prior to the publication of the USF safe exposure time …

The Natural History Of Human Papillomavirus Related Condyloma In A Multinational Cohort Of Men, Gabriella Anic

USF Tampa Graduate Theses and Dissertations

Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States, but few studies have examined the progression from HPV infection to disease in men. Genital condyloma are the most common clinical manifestation of HPV infection. Though not associated with mortality, condyloma are a source of emotional distress, and treatment is often painful with a high recurrence rate. The aims of this study were to examine the distribution of HPV types present on the surface of condyloma, estimate the incidence of condyloma overall and after type-specific HPV infections, assess the sociodemographic and sexual behavior factors independently associated …

Physical Activity Promotion Among School-Aged Children Using Pedometers And Rewards, Kari E. Ek

USF Tampa Graduate Theses and Dissertations

Physical activity is important for children as many children are considered overweight or obese. The benefits of exercise have been demonstrated in empirical studies across all age ranges (Horne, Hardman, Lowe, & Rowlands, 2009; Kelly et al., 2004; Louie & Chan, 2003; Southard & Southard, 2006). In the current study, a multiple baseline design across participants was used to assess the effectiveness of goal setting, reinforcement contingencies, and pedometers that provide feedback to increase step count of 5 participants. During baseline each participant wore a sealed pedometer to assess the average steps the participants took per day. After baseline, each …

The Effect Of Various Carbohydrate Supplements On Postprandial Blood Glucose Response In Female Soccer Players, Nina Pannoni

USF Tampa Graduate Theses and Dissertations

PURPOSE: The purpose of this study is to examine the effects of different types of carbohydrates on blood glucose response in collegiate soccer athletes at rest. This will help to determine the effectiveness of a carbohydrate supplement in providing sustained energy and maintained performance if ingested prior to a soccer match. METHODS: In a cross-over design, 10 female collegiate soccer players (n= 10, age 20.10 ± .99 years, height 65.55 ± 2.77 inches, weight 64.12 ± 8.36 kilograms) from the University of South Florida reported to the laboratory on five separate occasions after an overnight fast. Once a baseline blood …

Egyptian Body Size: A Regional And Worldwide Comparison, Michelle H. Raxter

USF Tampa Graduate Theses and Dissertations

Human body size and limb proportions can provide important information about adaptation, population movements, and health disparities. This study investigated changes in body size and limb proportions of adult Egyptians temporally and geographically in relation to climatological, sociopolitical and economic developments. It was predicted that Egyptian groups that experienced more environmental stress would be shorter and exhibit less sexual dimorphism. It was also predicted that Egyptians would be intermediate between higher and lower latitude populations in body form and limb length ratios. The main skeletal sample consisted of 492 males and 528 females, all adults from the Predynastic and Dynastic …

Apparent Total Evaporative Resistance For Clothing Ensembles At High Heat Stress Levels, Patrick Rodriguez

USF Tampa Graduate Theses and Dissertations

Donning protective clothing for mitigation of hazard from chemical agents poses a problem in the form of heat stress. When choosing protective clothing, many factors must be taken into account including insulative properties and evaporative resistance. This study calculated and compared R_e,T,a for three clothing ensembles at levels of heat stress past the level of compensation for heat gain to determine if R_e,T,a values varied or remained the same with changes in heat stress level. A three-way mixed model analysis of variance demonstrated significant differences for estimated R_e,T,a values among ensembles, heat stress levels and interactions among …

Secreted Factors From Human Umbilical Cord Blood Cells Protect Oligodendrocytes From Ischemic Insult, Derrick Rowe

USF Tampa Graduate Theses and Dissertations

Oligodendrocytes (OL)s are the dominant cell type in the white matter and are integral for synaptic transmission essential for proper neuronal communication between brain areas. Previous studies have shown that intravenous administration of the mononuclear fraction of human umbilical cord blood (HUCB) cells in rat models of stroke reduced white matter injury, gray matter injury and behavioral deficits. Yet the mechanisms used by HUCB cells remain unknown in ischemic injury. These studies will investigate both in vitro and in vivo approaches to elucidate this mechanism in OLs. When mature primary OLs were coincubated with HUCB cells, HUCB cells secreted soluble …

Identification Of Patient Recovery Patterns After Cardiovascular Surgery Based On Laboratory Tests Results, Alcides Ricardo Santander Mercado

USF Tampa Graduate Theses and Dissertations

In this dissertation is proposed a methodology to identify patient's recovery patterns after cardiovascular surgery based on laboratory tests results. The main purpose is to enhance the understanding of the manifestations of postsurgical complications in patients who underwent cardiovascular surgery. The analysis of patients' recovery process is based on the relationship between plasma calcium, ionized calcium and platelet count over time.

Laboratory results from the James A. Haley Veterans' Hospital databases, related to patients admitted to the Surgical Intensive Care Unit (SICU) after cardiac surgery (coronary artery bypass, aortic value replacement and mitral valve replacement), are used. These databases contain …

The Relationship Of Mid-Pregnancy Levels Of Cytokines, Stress, And Depression With Gestational Age At Delivery, Melissa Molinari Shelton

USF Tampa Graduate Theses and Dissertations

Pregnancy is a time of alternating states of inflammation. The establishment of pregnancy is marked by controlled inflammation and transition toward an anti-inflammatory state for much of the gestational period before returning to an inflammatory state at the onset of labor. Stress and depression trigger the HPA Axis to produce cortisol and levels are maintained in a state of elevation during pregnancy and continue to rise before parturition.

The aim of this research was to explore the relationship of gestational age at delivery with mid-pregnancy levels of cytokines, stress and depression. Participant samples (N = 122) were collected between 16 …

Sisters In Arms: A Case Study Of The Experiences Of Women Warriors In The United States Military, Carmen Teresa Stein-Mccormick

USF Tampa Graduate Theses and Dissertations

Presently there are few studies that describe the current experiences of women warriors relative to issues such as sexual hostility, sexual harassment, and other uncommon experiences during their military careers. Very little is known about how being a woman in a male-dominated military may affect women warriors' choices between making the military a career or returning to civilian life. With better understanding of women warriors' military experiences, mental health professionals, educators, and other human services professionals may have a better understanding of the issues that may affect women in the military. To date there are limited studies that have examined …

Indicators Of Early Adult And Current Personality In Parkinson's Disease, Kelly Sullivan

USF Tampa Graduate Theses and Dissertations

Introduction: Previous epidemiologic studies suggest that the personality of Parkinson's disease (PD) patients differs from that of controls, and laboratory evidence supports a potential common pathophysiology of personality traits and PD. One nested case-control study found that PD cases were significantly more anxious than controls before the clinical onset of the disease, and additional data suggest that certain occupations may be risk factors for the disease. Additionally, the latent period that precedes the onset of motor symptoms of PD is unknown.

Objectives: The objectives of this study were to evaluate the association of PD with objective indicators of current and …

Patient Safety In Nursing Homes, Kali Thomas

USF Tampa Graduate Theses and Dissertations

Safety of residents has gained increased popularity in recent years following a report from the Institute of Medicine attributing 98,000 hospital deaths each year to errors by staff. As a result, regulatory agencies, advocates, and health care providers have shifted their focus to understanding patient safety and developing a culture that promotes safety. However, nursing homes lag behind other health care providers in their adoption of a patient safety culture and understanding what factors affect safety in resident care. These insights are needed to ensure that nursing home residents receive the safe care.

The purpose of this dissertation is to …

The Effects Of Manipulating Conditioned Establishing Operations On The Acquisition Of Mands In Children With Autism Spectrum Disorders, Claudia Troconis

USF Tampa Graduate Theses and Dissertations

In Verbal Behavior, Skinner (1957) suggested that each verbal operant has independent response functions, in which acquiring one does not automatically result in the other, unless transfer between the verbal operants is directly trained. Although several researchers have shown that mands and tacts are functionally independent, more recent research has demonstrated that mands may emerge following tact training. However, this research has not clarified the influence of establishing operations on the emergence of pure mands following tact training. Therefore, the present study investigated the effects of tact training on the acquisition of impure and pure mands in children with autism …

School Psychologists' Communication And Collaboration With Community-Based Mental Health Professionals, Audra St. John Walsh

USF Tampa Graduate Theses and Dissertations

Although collaboration between school psychologists and community-based mental health professionals is essential in the provision of comprehensive and effective mental health services for youth with intensive mental health needs, youth may not receive the full benefit of these coordinated efforts, as collaboration may not occur as often as it should. This study investigated the frequency of communication and collaboration between school- and community-based professionals, the purposes and methods of communication, and the benefits and barriers to collaboration. Survey data from 80 members of the Florida Association of School Psychologists were collected and analyzed. Forty-three percent of school psychologists reported communicating …

Detection Of Polybrominated Diphenyl Ethers In Ambient Air At A Wastewater Treatment Facility In Tampa, Florida, Brenda L. White

USF Tampa Graduate Theses and Dissertations

The goal of this study was to quantify the ambient air concentrations of polybrominated diphenyl ethers (PBDEs) from three locations within the Howard Curren Wastewater Treatment Facility located in Tampa, Florida. PBDEs have been linked to endocrine disruption, cancer, developmental concerns in children, as well as other toxic effects; however their precise roles concerning these deleterious effects remains to be determined. The present study was motivated by these potential health concerns posed by inhalational exposure to PBDEs. Ambient air was monitored with a Tisch Environmental PUF high volume sampler for 48 hours with collection on three types of media-quarts filter, …

Contextualizing Hiv/Aids Prevention And Treatment Programs In Zanzibar, Tanzania, Naheed Ahmed

USF Tampa Graduate Theses and Dissertations

International aid organizations and wealthy nations have contributed billions to combat the spread and treatment of HIV/AIDS in sub-Saharan Africa; however, these programs have been critiqued for not addressing the socioeconomic and cultural context of the epidemic, instead relying upon generalized approaches. The prevalence rate in Zanzibar, Tanzania is low in the general population, but high among vulnerable segments of Zanzibari society, resulting in interventions focusing on particular groups (e.g. sex workers, drug users, and men who have sex with men). Through interviews with government agencies, non-profit organizations, medical professionals, vulnerable populations, and HIV/AIDS patients, this paper examines how local …

Identification And Characterization Of The Human Herpesviruses 6a And 6b Genome Integration Into Telomeres Of Human Chromosomes During Latency, Jesse Herbert Arbuckle

USF Tampa Graduate Theses and Dissertations

While the latent genome of most Herpesviruses persists as a nuclear circular episome, previous research has suggested that Human Herpesvirus 6 (HHV-6) may integrate into host cell chromosomes, and be vertically transmitted in the germ-line. Because the HHV-6 genome encodes a perfect TTAGGG telomere repeat array at the right end direct repeat (DR_R) and an imperfect TTAGGG repeat at the end of the left end direct repeat (DR_L), we established a hypothesis that during latency, the HHV-6A and HHV-6B genome integrates into the telomeres of human chromosomes through homologous recombination with the n(TTAGGG) viral repeats, and …

Drug Courts Work, But How? Preliminary Development Of A Measure To Assess Drug Court Structure And Processes, Blake Barrett

USF Tampa Graduate Theses and Dissertations

The high prevalence of substance use disorders is well-documented among criminal offenders. Drug courts are specialty judicial programs designed to: 1) improve public safety outcomes; 2) reduce criminal recidivism and substance abuse among offenders with substance use disorders; and 3) better utilize scarce criminal justice and treatment resources. Drug courts operate through partnerships between the criminal justice, behavioral health and public health systems. Offenders participate in an intensive regimen of substance abuse treatment and case management while under close judicial supervision. Drug courts' effectiveness in reducing criminal recidivism and drug use has been documented through numerous primary studies as well …

An Examination Of The Impact Of Preconception Health On Adverse Pregnancy Outcomes Through The Theoretical Lens Of Reciprocal Determinism, Mary Elizabeth Buie

USF Tampa Graduate Theses and Dissertations

Statement of Purpose

The purpose of this study is to examine the impact of preconception health on adverse pregnancy outcomes through the theoretical lens of reciprocal determinism. Thus, this study aims to develop a preconception health conceptual framework that accounts for the interactive relationships among behavior, the environment, and the person.

Rationale for the Study

Women may not recognize a pregnancy until the first or second missed menstrual cycle, a full four to eight weeks or more after conception. Once a woman realizes the possibility of a pregnancy, it takes further time to confirm the pregnancy with a home pregnancy …

An Evaluation Of Booster Training Using Video Modeling With Foster Parents, Anna Katherine Caravello

USF Tampa Graduate Theses and Dissertations

In order for foster parents to be prepared to manage problem behavior and develop a positive relationship with a child in their home, local foster care agencies require these parents to attend parent training classes. Unfortunately, even foster care agencies that offer empirically validated parent training courses are unable to prevent the parents' performance from decreasing over time (Cowart, Iwata, & Poynter, 1984; Forehand & King, 1977; Mueller et al., 2003). However, researchers have created booster training sessions to counteract this issue. Booster training sessions allow participants to attend a brief refresher course on skills they have previously learned. Another …

Making A Splash: Eliminating Water Phobia And Increasing Confident Water Skills, Paula Elizabeth Chan

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to utilize a multi-component intervention to increase confident water skills for three typically developing children, and to evaluate whether fearful behaviors decreased as the intervention progressed. The intervention, comprised of goal setting, self-monitoring, behavioral skills training and positive reinforcement, was used in community pools to teach basic water skills. Results suggest the intervention was successful in increasing confident water skills, while intervals with positive affect and fearful behaviors demonstrated variability.

The Impact Of Pharmacy Work Design On Pharmacist Productivity, Nicholas Allen Coblio

USF Tampa Graduate Theses and Dissertations

Healthcare costs in the United States continue to grow at an alarming rate. Concerning the cost of medications, there are a number of factors that drive these costs. While personnel costs are not the largest of these, they do contribute a significant portion. The cost of the cognitive component of order processing by pharmacists can range from three dollars to over six dollars per prescription depending on the production throughput of the pharmacist.

Studies at the organization which was the focus of the research, as well as reports in the literature, indicated that work disruption and other environmental factors could …

Disparities In Survival And Mortality Among Infants With Congenital Aortic, Pulmonary, And Tricuspid Valve Defects By Maternal Race/Ethnicity And Infant Sex, Colleen Conklin

USF Tampa Graduate Theses and Dissertations

Background: The etiology of congenital heart valve defects is not well understood; little is known about the risk factors that contribute to the survival and mortality outcomes of children with these defects.

Methods: Using data from the Texas Birth Defects Registry (TBDR) we conducted a retrospective cohort study of 2070 singleton infants with congenital aortic, pulmonary, or tricuspid valve atresia or stenosis born in Texas between January 1, 1996 and December 31, 2007 to Hispanic, Non-Hispanic (NH) black, and NH white women. TBDR data were death-to-birth matched by the Texas Vital Statistics Unit for deaths between January 1, 1996 and …