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Articles 61 - 90 of 437
Full-Text Articles in Arts and Humanities
Consumer Response To Healthy Eating, Physical Activity And Weight-Related Recommendations: A Systematic Review, S Boylan, Jimmy Chun Yu Louie, T Gill
Consumer Response To Healthy Eating, Physical Activity And Weight-Related Recommendations: A Systematic Review, S Boylan, Jimmy Chun Yu Louie, T Gill
Jimmy Chun Yu Louie
Strong evidence linking poor diet and lack of physical activity to risk of obesity and related chronic disease has supported the development and promotion of guidelines to improve population health. Still, obesity continues to escalate as a major health concern, and so the impact of weight-related guidelines on behaviour is unclear. The aim of this review was to examine consumer response to weight-related guidelines. A systematic literature search was performed using Medline, PsycInfo, ProQuest Central and additional searches using Google and reference lists. Of the 1,765 articles identified, 46 relevant titles were included. Most studies examined attitudes towards content, source, …
The Diet Quality Of Women With Gestational Diabetes Mellitus, Jimmy Chun Yu Louie, T Markovic, D Foote, G Ross, Jennie Brand-Miller
The Diet Quality Of Women With Gestational Diabetes Mellitus, Jimmy Chun Yu Louie, T Markovic, D Foote, G Ross, Jennie Brand-Miller
Jimmy Chun Yu Louie
No abstract provided.
Poor Food And Nutrient Intake Among Indigenous And Non-Indigenous Rural Australian Children, Josephine D. Gwynn, Victoria M. Flood, Catherine A. D'Este, John R. Attia, Nicole Turner, Janine Cochrane, Jimmy Chun Yu Louie, John H. Wiggers
Poor Food And Nutrient Intake Among Indigenous And Non-Indigenous Rural Australian Children, Josephine D. Gwynn, Victoria M. Flood, Catherine A. D'Este, John R. Attia, Nicole Turner, Janine Cochrane, Jimmy Chun Yu Louie, John H. Wiggers
Jimmy Chun Yu Louie
BACKGROUND: The purpose of this study was to describe the food and nutrient intake of a population of rural Australian children particularly Indigenous children. Participants were aged 10 to 12 years, and living in areas of relative socio-economic disadvantage on the north coast of New South Wales. METHODS: In this descriptive cross-sectional study 215 children with a mean age of 11.30 (SD 0.04) years (including 82 Indigenous children and 93 boys) completed three 24-hour food recalls (including 1 weekend day), over an average of two weeks in the Australian summer of late 2005. RESULTS: A high proportion of children consumed …
Eight Is Enough?: The Ethics Of The California Octuplets Case, Scott Paeth
Eight Is Enough?: The Ethics Of The California Octuplets Case, Scott Paeth
Scott R. Paeth
The recent California octuplets case raises a number of important issues that need to be addressed in the context of the increasingly widespread practice of in vitro fertilization. This paper explores some of those issues as looked at from the perspective of protestant theological ethics and public theology, examining the moral responsibilities of the various participants in the process, both before and after the octuplets’ birth, including the mother, her doctors, the health care bureaucracy, the wider society, and the media. Each of these participants failed in significant respects to consider the ethical implications of the births in this complicated …
Differences In Membrane Acyl Phospholipid Composition Between An Endothermic Mammal And An Ectothermic Reptile Are Not Limited To Any Phospholipid Class, Stephen J. Blanksby, Todd W. Mitchell, Anthony J. Hulbert, Paul Else, K Ekroos
Differences In Membrane Acyl Phospholipid Composition Between An Endothermic Mammal And An Ectothermic Reptile Are Not Limited To Any Phospholipid Class, Stephen J. Blanksby, Todd W. Mitchell, Anthony J. Hulbert, Paul Else, K Ekroos
Stephen Blanksby
This study examined questions concerning differences in the acyl composition of membrane phospholipids that have been linked to the faster rates of metabolic processes in endotherms versus ectotherms. In liver, kidney, heart and brain of the ectothermic reptile, Trachydosaurus rugosus, and the endothermic mammal, Rattus norvegicus, previous findings of fewer unsaturates but a greater unsaturation index (UI) in membranes of the mammal versus those of the reptile were confirmed. Moreover, the study showed that the distribution of phospholipid head-group classes was similar in the same tissues of the reptile and mammal and that the differences in acyl composition were present …
Human Lens Lipids Differ Markedly From Those Of Commonly Used Experimental Animals, Jane Deeley, Todd W. Mitchell, Xiaojia Wei, Jurgen Korth, Jessica Hughes, Stephen J. Blanksby, Roger J. Truscott
Human Lens Lipids Differ Markedly From Those Of Commonly Used Experimental Animals, Jane Deeley, Todd W. Mitchell, Xiaojia Wei, Jurgen Korth, Jessica Hughes, Stephen J. Blanksby, Roger J. Truscott
Stephen Blanksby
Electrospray ionisation tandem mass spectrometry has allowed the unambiguous identification andquantification of individual lens phospholipids in human and six animal models. Using this approach ca. 100unique phospholipids have been characterised. Parallel analysis of the same lens extracts by a novel directinsertionelectron-ionization technique found the cholesterol content of human lenses to be significantlyhigher (ca. 6 times) than lenses from the other animals.The most abundant phospholipids in all the lenses examined were choline-containing phospholipids. In rat,mouse, sheep, cow, pig and chicken, thesewere present largely as phosphatidylcholines, in contrast 66% of thetotal phospholipid in Homo sapienswas sphingomyelin, with the most abundant being dihydrosphingomyelins,in …
Dissociation Mediates The Relationship Between Childhood Trauma And Hallucination-Proneness., F Varese, E Barkus, R P. Bentall
Dissociation Mediates The Relationship Between Childhood Trauma And Hallucination-Proneness., F Varese, E Barkus, R P. Bentall
Emma Barkus
BACKGROUND: It has been proposed that the relationship between childhood trauma and hallucinations can be explained by dissociative processes. The present study examined whether the effect of childhood trauma on hallucination-proneness is mediated by dissociative tendencies. In addition, the influence of dissociative symptoms on a cognitive process believed to underlie hallucinatory experiences (i.e. reality discrimination; the capacity to discriminate between internal and external cognitive events) was also investigated.MethodPatients with schizophrenia spectrum disorders (n=45) and healthy controls (with no history of hallucinations; n=20) completed questionnaire measures of hallucination-proneness, dissociative tendencies and childhood trauma, as well as performing an auditory signal detection …
Group Cohesion And Homework Adherence In Multi-Family Group Therapy For Schizophrenia, Frank P. Deane, Joanne Mercer, Anahita Talyarkhan, Gordon Lambert, Judy Pickard
Group Cohesion And Homework Adherence In Multi-Family Group Therapy For Schizophrenia, Frank P. Deane, Joanne Mercer, Anahita Talyarkhan, Gordon Lambert, Judy Pickard
Frank Deane
This study examined the relationship between levels of group cohesion, defined as whole group relationships, and between-session therapeutic homework adherence in a multi-family group therapy (MFGT) for people with schizophrenia. Participants from 18 consenting families attending MFGT groups completed weekly homework adherence ratings, group cohesion and spontaneous between-session activity measures. Levels of group cohesion at each session were compared with measures of scheduled and spontaneous homework adherence reported at the next session. It was hypothesised that higher levels of group cohesion would be related to homework adherence and other spontaneous between-session therapeutic activity completed by group members. Results show higher …
Study Protocol: A Randomized Controlled Trial Of A Computer-Based Depression And Substance Abuse Intervention For People Attending Residential Substance Abuse Treatment, Peter J. Kelly, Frances Kay-Lambkin, Amanda Baker, Frank P. Deane, Adam C. Brooks, Alexandra Mitchell, Sarah Marshall, Meredith Whittington, Genevieve A. Dingle
Study Protocol: A Randomized Controlled Trial Of A Computer-Based Depression And Substance Abuse Intervention For People Attending Residential Substance Abuse Treatment, Peter J. Kelly, Frances Kay-Lambkin, Amanda Baker, Frank P. Deane, Adam C. Brooks, Alexandra Mitchell, Sarah Marshall, Meredith Whittington, Genevieve A. Dingle
Frank Deane
"Background: A large proportion of people attending residential alcohol and other substance abuse treatment have a co-occurring mental illness. Empirical evidence suggests that it is important to treat both the substance abuse problem and co-occurring mental illness concurrently and in an integrated fashion. However, the majority of residential alcohol and other substance abuse services do not address mental illness in a systematic way. It is likely that computer delivered interventions could improve the ability of substance abuse services to address co-occurring mental illness. This protocol describes a study in which we will assess the effectiveness of adding a computer delivered …
Histamine H1 Receptor Agonist And Control Of Olanzapine-Induced Obesity, Jiamei Lian, Xu-Feng Huang, N Pai, C Deng
Histamine H1 Receptor Agonist And Control Of Olanzapine-Induced Obesity, Jiamei Lian, Xu-Feng Huang, N Pai, C Deng
Xu-Feng Huang
No abstract provided.
Effects Of Simvastatin And 6-Hydroxydopamine Lesion On Histaminergic H1 Receptor Binding In Rat Brains, C H. Hu, C Deng, Xu-Feng Huang, J Chen, Q Wang
Effects Of Simvastatin And 6-Hydroxydopamine Lesion On Histaminergic H1 Receptor Binding In Rat Brains, C H. Hu, C Deng, Xu-Feng Huang, J Chen, Q Wang
Xu-Feng Huang
No abstract provided.
The Effects Of Antipsychotics On The Density Of Cannabinoid Receptors In The Dorsal Vagal Complex Of Rats: Implications For Olanzapine-Induced Weight Gain, Katrina Weston-Green, Xu-Feng Huang, Mei Han, Chao Deng
The Effects Of Antipsychotics On The Density Of Cannabinoid Receptors In The Dorsal Vagal Complex Of Rats: Implications For Olanzapine-Induced Weight Gain, Katrina Weston-Green, Xu-Feng Huang, Mei Han, Chao Deng
Xu-Feng Huang
Some atypical antipsychotics clinically used to treat schizophrenia induce weight gain by unknown mechanisms. The dorsal vagal complex (DVC) of the brainstem and the endogenous cannabinoid system are implicated in the regulation of appetite signalling and food intake. We investigated whether antipsychotic drugs alter cannabinoid receptor-binding density in the DVC. Female Sprague–Dawley rats were treated with olanzapine, haloperidol, aripiprazole or vehicle for 1 wk (short-term) or 12 wk (chronic). Quantitative autoradiographic methods were employed to investigate the binding density of cannabinoid receptors in the DVC using a highly sensitive Beta Imager. Short-term olanzapine induced a significant 39% decrease in cannabinoid …
Use Of Homework By Mental Health Case Managers In The Rehabilitation Of Persistent And Recurring Psychiatric Disability, Peter Kelly, Frank P. Deane, Nikolaos Kazantzis, Trevor P. Crowe, Lindsay G. Oades
Use Of Homework By Mental Health Case Managers In The Rehabilitation Of Persistent And Recurring Psychiatric Disability, Peter Kelly, Frank P. Deane, Nikolaos Kazantzis, Trevor P. Crowe, Lindsay G. Oades
Frank Deane
Background: Homework refers to between-session activities that are tied to therapeutic goals. Homework has been suggested as being an important clinical adjunct to case management practices, however, to date, research has not examined case managers’ use of homework. Aims: To identify the degree that case managers use homework within their clinical practice and explore the way it is administered with people diagnosed with a persistent and recurring psychiatric illness. Method: A survey was completed by 122 case managers (63% of those approached) comprising nurses, psychologists, social workers, occupational therapists and welfare/support workers. Results: Ninety-three percent of case managers implement homework, …
Neuropeptide Y Mrna Expression Levels Following Chronic Olanzapine, Clozapine And Haloperidol Administration In Rats, Xu-Feng Huang, Katerina Zavitsanou, Chao Deng
Neuropeptide Y Mrna Expression Levels Following Chronic Olanzapine, Clozapine And Haloperidol Administration In Rats, Xu-Feng Huang, Katerina Zavitsanou, Chao Deng
Xu-Feng Huang
No abstract provided.
Inter-Meal Interval Is Increased In Mice Fed A High Whey, As Opposed To Soy And Gluten, Protein Diets, Xu-Feng Huang, Timothy South, Yinghua Yu
Inter-Meal Interval Is Increased In Mice Fed A High Whey, As Opposed To Soy And Gluten, Protein Diets, Xu-Feng Huang, Timothy South, Yinghua Yu
Xu-Feng Huang
This study aimed to characterise meal patterns and satiety effects of diets that are high in protein but differ in protein source. Using a computerised automatic recording system, meal pattern behaviour was recorded continuously for 7 days in mice fed single (whey, soy or gluten) or different combined protein diets. Overall, average energy intake was significantly lower in mice fed a whey protein diet than those fed soy, gluten and lab chow diets. Among these four diets, the inter-meal interval of mice fed a whey protein diet was the longest and their meal number was the lowest. Combination of whey …
Decreased Density Of Serotonin 2a Receptors In The Superior Temporal Gyrus In Schizophrenia - A Postmortem Study, Xu-Feng Huang, Chao Deng, Qing Wang, Kai Kang
Decreased Density Of Serotonin 2a Receptors In The Superior Temporal Gyrus In Schizophrenia - A Postmortem Study, Xu-Feng Huang, Chao Deng, Qing Wang, Kai Kang
Xu-Feng Huang
The superior temporal gyrus (STG) is strongly implicated in the pathophysiology of schizophrenia,particularly with regards to auditory hallucinations. In this study, using in situ quantitative autoradiography in postmortem tissue, we investigated the binding of the [3H]ketanserin to 5-HT2A receptors and [3H] mesulergine to 5-HT2C receptors in the left STG of 8 male schizophrenic patients compared to 8 control subjects. A strong [3H]ketanserin binding was observed in the STG, however there was a very weak [3H] mesulergine binding in the STG. A significant decrease in binding of [3H]ketanserin was clearly observed in schizophrenia patients in comparison with control subjects. There were …
The Schizophrenia Susceptibility Gene Neuregulin 1 Modulates Tolerance To The Effects Of Canabinoids, Aurelie Boucher, Glenn E. Hunt, Jacques Micheau, Xu-Feng Huang, Iain Mcgregor, Tim Karl, Jonathon Arnold
The Schizophrenia Susceptibility Gene Neuregulin 1 Modulates Tolerance To The Effects Of Canabinoids, Aurelie Boucher, Glenn E. Hunt, Jacques Micheau, Xu-Feng Huang, Iain Mcgregor, Tim Karl, Jonathon Arnold
Xu-Feng Huang
Cannabis increases the risk of schizophrenia in genetically vulnerable individuals. In this study we aim to show that the schizophrenia susceptibility gene neuregulin 1 (Nrg1) modulates the development of tolerance to cannabinoids in mice. Nrg1 heterozygous (HET) and wild-type (WT) mice were treated daily for 15 d with the synthetic analogue of D9-tetrahydrocannabinol, CP55,940 (0.4 mg/kg). We measured the impact of this exposure on locomotor activity, anxiety, prepulse inhibition (PPI), body temperature and FosB/DFosB immunohistochemistry. Tolerance to CP55,940-induced hypothermia and locomotor suppression developed more rapidly in Nrg1 HET mice than WT mice. Conversely in the light-dark test, while tolerance to …
Short- And Long-Term Effects Of Antipsychotic Drug Treatment On Weight Gain And H1 Receptor Expression, Kelly Newell, Xu-Feng Huang, Chao Deng, Tom Burne, Mei Han
Short- And Long-Term Effects Of Antipsychotic Drug Treatment On Weight Gain And H1 Receptor Expression, Kelly Newell, Xu-Feng Huang, Chao Deng, Tom Burne, Mei Han
Xu-Feng Huang
The present study investigated body weight gain, food intake, open-field activity and brain histamine H1 receptor mRNA and protein expression in rats treated with three types of antipsychotics. Rats were divided into eight groups and treated with aripiprazole (2.25mg/kg/day), olanzapine (1.5mg/kg/day), haloperidol (0.3mg/kg/day) or vehicle (as control) for 1 or 12 weeks. Administration of olanzapine for 1 week led to a threefold increase in body weight gain and a 35% increase in fat deposits compared to controls (p<0.05). In the 12-week olanzapine treatment group, accumulative food intake was significantly higher in the first 7 weeks of treatment compared to …
Ventromedial Hypothalamic Npy Y2 Receptor In The Maintenance Of Body Weight In Diet-Induced Obesity In Mice, Yulin Li, Xu-Feng Huang, Chao Deng, Qing Wang, Timothy South, Yinghua Yu
Ventromedial Hypothalamic Npy Y2 Receptor In The Maintenance Of Body Weight In Diet-Induced Obesity In Mice, Yulin Li, Xu-Feng Huang, Chao Deng, Qing Wang, Timothy South, Yinghua Yu
Xu-Feng Huang
This study examined changes in neuropeptide Y (NPY) Y2 receptor binding in the brains of C57BL/6 mice in response to different levels of high-fat diets via three dietary intervention methods: high-fat diet, switching from high- to low-fat diet and finally, energy restricted high-fat diet. Forty-five C57Bl/6 male mice were fed a high-fat diet for 8 weeks and then classified as diet-induced obese (DIO) or diet-resistant (DR) mice according to the highest and lowest body weight gainers, respectively. The DIO and DR mice were then randomly divided into three groups each and either continued on their high-fat diet ad libitum (DIO-H …
Increased Cannabinoid Receptor Density In The Posterior Cingulate Cortex In Schizophrenia, Kelly Newell, Xu-Feng Huang, Chao Deng
Increased Cannabinoid Receptor Density In The Posterior Cingulate Cortex In Schizophrenia, Kelly Newell, Xu-Feng Huang, Chao Deng
Xu-Feng Huang
No abstract provided.
A Link Between Chronic Sleep Restriction And Obesity: Methodological Considerations, Christopher Magee, Donald Iverson, Xu-Feng Huang, Peter Caputi
A Link Between Chronic Sleep Restriction And Obesity: Methodological Considerations, Christopher Magee, Donald Iverson, Xu-Feng Huang, Peter Caputi
Xu-Feng Huang
Emerging evidence suggests that chronicsleeprestriction contributes to obesity. Targeting short sleep duration may therefore offer a novel and effective method of preventing and treating obesity. However, this area of research is only in its infancy, and a complete understanding of how chronicsleeprestriction and obesity are linked is currently lacking. The aim of this paper is to briefly review epidemiological evidence for an association between chronicsleeprestriction and obesity in adults, and outline the key methodological limitations of these studies. Particular attention is paid to the methods used to measure sleep and obesity, as well as the need to control for potential …
A Static Handgrip Method For Distal Quantitative Sweat Measurements, Xu-Feng Huang, Chao Deng, Qing Wang, Einar Wilder-Smith, Kannan T. Aravinda, Yiong H. Chan, Erle C Lim
A Static Handgrip Method For Distal Quantitative Sweat Measurements, Xu-Feng Huang, Chao Deng, Qing Wang, Einar Wilder-Smith, Kannan T. Aravinda, Yiong H. Chan, Erle C Lim
Xu-Feng Huang
No abstract provided.
Obese Reversal By A Chronic Energy Restricted Diet Leaves An Increased Arc Npy/Agrp, But No Alteration In Pomc/Cart, Mrna Expression In Diet-Induced Obese Mice, Xu-Feng Huang, Chao Deng, Yinghua Yu
Obese Reversal By A Chronic Energy Restricted Diet Leaves An Increased Arc Npy/Agrp, But No Alteration In Pomc/Cart, Mrna Expression In Diet-Induced Obese Mice, Xu-Feng Huang, Chao Deng, Yinghua Yu
Xu-Feng Huang
No abstract provided.
Dietary Fat And Carbohydrate Composition: Metabolic Disease, Marc Brown, Len Storlien, Xu-Feng Huang, Linda Tapsell, Paul Else, Janine Higgins, Ian Brown
Dietary Fat And Carbohydrate Composition: Metabolic Disease, Marc Brown, Len Storlien, Xu-Feng Huang, Linda Tapsell, Paul Else, Janine Higgins, Ian Brown
Xu-Feng Huang
No abstract provided.
Short Term Effects Of Energy Restriction And Dietary Fat Sub-Type On Weight Loss And Disease Risk Factors, Linda C. Tapsell, Marijka Batterham, Xu-Feng Huang, Sze Yen Tan, Grigorijs Teuss, Karen E. Charlton, Jane E. O'Shea, Eva M. Warensjo
Short Term Effects Of Energy Restriction And Dietary Fat Sub-Type On Weight Loss And Disease Risk Factors, Linda C. Tapsell, Marijka Batterham, Xu-Feng Huang, Sze Yen Tan, Grigorijs Teuss, Karen E. Charlton, Jane E. O'Shea, Eva M. Warensjo
Xu-Feng Huang
Background and aims: Decreasing energy intake relative to energy expenditure is the indisputable tenet of weight loss. In addition to caloric restriction modification of the type of dietary fat may provide further benefits. The aim of the present study was to examine the effect of energy restriction alone and with dietary fat modification on weight loss and adiposity, as well as on risk factors for obesity related disease. Methods and results: One-hundred and fifty overweight men and women were randomized into a 3 month controlled trial with four low fat (30% energy) dietary arms: (1) isocaloric (LF); (2) isocaloric with …
The Comparison Of The Effect Of Oat And Shiitake Mushroom Powder To Prevent Body Weight Gain In Rats Fed High Fat Diet, Dian Handayani, Barbara J. Meyer, Jiezhong Chen, Patricia Tang, Philip Chi Lip Kwok, Hak-Kim Chan, Xu-Feng Huang
The Comparison Of The Effect Of Oat And Shiitake Mushroom Powder To Prevent Body Weight Gain In Rats Fed High Fat Diet, Dian Handayani, Barbara J. Meyer, Jiezhong Chen, Patricia Tang, Philip Chi Lip Kwok, Hak-Kim Chan, Xu-Feng Huang
Xu-Feng Huang
Preventing obesity could be done by lowering plasma TAG that inhibits adipogenesis. Oat and mushroom beta-glucans in the diet has been reported to lower plasma lipid; however the data focusing on their effects on TAG and obesity are insufficient. In the present study, lowering plasma triacylglycerol, fat deposition, body weight gain (BWG) in rats fed a high fat diet (HFD) was evaluated. Rats in the control group were given HFD only and rats in the treatment group fed HFD enriched with 0.2%, 0.6% and 1.8% (wt:wt) beta-glucan from oats (LD-O, MD-O, HD-O) or mushroom (LD-M, MD-M, HD-M). After 6 weeks …
A Behavioural Comparison Of Acute And Chronic Δ9-Tetrahydrocannabinol And Cannabidiol In C57bl/6jarc Mice, Ian Mcgregor, Xu-Feng Huang, Tim Karl, Jonathon Arnold, Rose Chesworth, Leonora E. Long
A Behavioural Comparison Of Acute And Chronic Δ9-Tetrahydrocannabinol And Cannabidiol In C57bl/6jarc Mice, Ian Mcgregor, Xu-Feng Huang, Tim Karl, Jonathon Arnold, Rose Chesworth, Leonora E. Long
Xu-Feng Huang
Cannabis contains over 70 unique compounds and its abuse is linked to an increased risk of developing schizophrenia. The behavioural profiles of the psychotropic cannabis constituent Δ9-tetrahydrocannabinol (Δ9-THC) and the non-psychotomimetic constituent cannabidiol (CBD) were investigated with a battery of behavioural tests relevant to anxiety and positive, negative and cognitive symptoms of schizophrenia. Male adult C57BL/6JArc mice were given 21 daily intraperitoneal injections of vehicle, Δ9-THC (0.3, 1, 3 or 10 mg/kg) or CBD (1, 5, 10 or 50 mg/kg). Δ9-THC produced the classic cannabinoid CB1 receptor-mediated tetrad of hypolocomotion, analgesia, catalepsy and hypothermia while CBD had modest hyperthermic effects. …
Membrane Phospholipid Composition, Alterations In Neurotransmitter Systems And Schizophrenia, Xu-Feng Huang, Chao Deng, Teresa Du Bois
Membrane Phospholipid Composition, Alterations In Neurotransmitter Systems And Schizophrenia, Xu-Feng Huang, Chao Deng, Teresa Du Bois
Xu-Feng Huang
No abstract provided.
Effects Of Diets High In Whey, Soy, Red Meat And Milk Protein On Body Weight Maintenance In Diet-Induced Obesity In Mice, Xu-Feng Huang, Y Liu, Gita Rahardjo, Peter Mclennan, Linda Tapsell, William Buttemer
Effects Of Diets High In Whey, Soy, Red Meat And Milk Protein On Body Weight Maintenance In Diet-Induced Obesity In Mice, Xu-Feng Huang, Y Liu, Gita Rahardjo, Peter Mclennan, Linda Tapsell, William Buttemer
Xu-Feng Huang
This study examined the effects of different food sources of protein on energy intake, body weight maintenance, and on the responses of plasma leptin, insulin and adiponectin in chronic high-fat diet-induced obese mice. Obesity was induced in 47 mice with a high-fat diet for 20 weeks. They were divided into five diet groups to test the effects of a higher protein proportion (30% energy), achieved at the expense of carbohydrate. For the next eight weeks, four of the groups were fed diets of chow formulated with whey, soy, red meat or milk while the control group continued on their high-fat …
No Changes In Densities Of Cannabinoid Receptors In The Superior Temporal Gyrus In Schizophrenia, Xu-Feng Huang, Chao Deng, Mei Han
No Changes In Densities Of Cannabinoid Receptors In The Superior Temporal Gyrus In Schizophrenia, Xu-Feng Huang, Chao Deng, Mei Han
Xu-Feng Huang
Objective: In recent years, abnormal changes in the endocannabinoid system have been found in schizophrenia. The superior temporal gyrus (STG) is strongly implicated in the pathophysiology of schizophrenia, particularly with regards to auditory hallucinations. In this study, we investigated the binding density of cannabinoid CB1 receptors in the STG of schizophrenia patients compared to control subjects. Methods: Quantitative autoradiography was used to investigate the binding densities of [3H] SR141716A (a selective antagonist) and [3H]CP-55940 (an agonist) to the CB1 receptors in the STG. Post-mortem brain tissue was obtained from the NSW Tissue Resource Centre (Australia). Results: Contrasting to previous findings …