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Theses/Dissertations

Depression

2021

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Protective Role Of Cod Liver Oil On Metabolic And Neurological Parameters In Rat Model Of Diabetic Depression, Roweena Sheryl Dec 2021

Protective Role Of Cod Liver Oil On Metabolic And Neurological Parameters In Rat Model Of Diabetic Depression, Roweena Sheryl

Kasturba Medical College, Mangalore Theses and Dissertations

No abstract provided.


Depression As A Moderator Of The Relationship Between Perceived Injustice And Neuropsychological Performance Validity Among Individuals Previously Diagnosed With A Concussion, Jeremiah Lum Dec 2021

Depression As A Moderator Of The Relationship Between Perceived Injustice And Neuropsychological Performance Validity Among Individuals Previously Diagnosed With A Concussion, Jeremiah Lum

Clinical Psychology Dissertations

Concussion is one of the most common conditions seen within rehabilitation and neuropsychology. Given that many concussions are diagnosed following litigation-associated injuries, it is unsurprising that malingered neurocognitive deficit (i.e., deliberate underperformance on cognitive instruments in the interest of secondary gain) has dominated the concussion literature. Although the identification of malingering is essential to ethical assessment, its presence or absence is not the sole determinant of performance validity as a whole. Rather, performance validity is a broad construct involving effort, which refers to examinees’ investment in performing at capacity levels; emerging research suggests this can be affected by psychological factors …


Smoking, Alcohol Consumption, And Depression In Association With Incidence Of Type 2 Diabetes Among Mexican Americans In Starr County, Texas, Gabriela Rubannelsonkumar Dec 2021

Smoking, Alcohol Consumption, And Depression In Association With Incidence Of Type 2 Diabetes Among Mexican Americans In Starr County, Texas, Gabriela Rubannelsonkumar

Honors Program Theses and Research Projects

Previous studies on conditions like obesity, hypertension, and type 2 diabetes mellitus (T2DM) have explored the correlations between them and various other human conditions, including aortic stiffness, left ventricular hypertrophy and sleep apnea, as they predict possibilities of developing certain diseases in Mexican Americans. This study aims to observe the correlation between lifestyle decisions that could relate to the onset of the depression in normal, prediabetic, and diabetic individuals. These include smoking habits and alcohol consumption. Many papers have previously conducted research on these lifestyle habits as they relate to obesity, hypertension, diabetes, however, have done so in a singular …


Bonded Or Broken? An Expansion Of Goodman And Gotlib’S Depressive Symptom Transmission Model Extended To Foster Parents And Grandparent Caregivers, Acacia Lopez Dec 2021

Bonded Or Broken? An Expansion Of Goodman And Gotlib’S Depressive Symptom Transmission Model Extended To Foster Parents And Grandparent Caregivers, Acacia Lopez

Theses and Dissertations

Current literature establishes a relationship between maternal depression and offspring depression. Goodman and Gotlib’s “Developmental Model for Understanding Mechanisms of Transmission” suggests possible mechanisms including attachment. Prior research also demonstrates a link between fathers’ depression and pediatric psychopathology risk, but further research is needed to elucidate the effect of other non-parental caregivers. Children raised by both types of non-parental caregivers are vulnerable to attachment disruptions due to separation from their parental caregivers and the prevalence of children residing with these caregivers is on the rise in recent years. Using the Goodman and Gotlib framework, this study examined the relation between …


Depression Screening Upon Admission At An Addiction Facility: A Quality Improvement Project, Eric Aniekwena Dec 2021

Depression Screening Upon Admission At An Addiction Facility: A Quality Improvement Project, Eric Aniekwena

Doctor of Nursing Practice

More than one in six Americans will have a diagnosis of a substance use disorder at some time in their life. According to the National Institute on Drug Abuse (2020), those with a substance use disorder will have an increased rate of having a comorbidity of depression or depression symptoms during treatment, leading to poorer outcomes. The purpose of this quality improvement project was to increase provider and staff adherence to the treatment standards outlined in the Veteran’s Affair/Department of Defense Clinical Practice Guideline for the Management of Major Depressive Disorder (Veteran’s Affairs/Department of Defense, 2016). During this 10-week process, …


Determining The Psychosocial Needs Of The Nurses Of Covid-19 Patients, Allison Stevens Dec 2021

Determining The Psychosocial Needs Of The Nurses Of Covid-19 Patients, Allison Stevens

ATU Theses and Dissertations 2021 - Present

Nurses are a vital element of the COVID-19 healthcare crisis and have been since the beginning of the COVID-19 response. The professional strain put on nurses included, but is not limited to: changing professional roles, rapidly changing policies and procedures, an influx of patients—particularly of high acuity, and change in workplace morale. However, nurses also had to carry the burdens of living as a member of society, family member, friend, community member, and above all, simply as a person surviving a pandemic themselves. With all of the stressors nurses have endured, it stands to reason that their psychosocial needs have …


Appreciation Day For Clinical Staff At Vna Hospice, Melody Nguyen Dec 2021

Appreciation Day For Clinical Staff At Vna Hospice, Melody Nguyen

Capstone Projects and Master's Theses

VNA Hospice of the Central Coast is a nonprofit that was created back in 1951. The staff at VNA are visiting about 75,000 homes per year. Throughout the years the staff have been seeing patients who reached the requirement of having 6 months or less to live. Working with Hospice patients can be hard for everyone but, the staff at VNA are seeing the patients from good days and bad days. Depression is known to negatively impact the clinical staff at VNA Hospice. Staff are working long hours which leads to sleep disturbance and chronic stress. Some staff are also …


Substance Use And Psychological Distress Correlates Of Sleep Quality Among College Students, Juanybeth Morales Ortega Dec 2021

Substance Use And Psychological Distress Correlates Of Sleep Quality Among College Students, Juanybeth Morales Ortega

Graduate Theses and Dissertations

Poor sleep quality in college students is a major problem associated with adverse health outcomes, cognitive performance, substance use, and psychological distress. Our study explored how substance use and psychological distress are associated with the sleep quality of college students. We analyzed secondary data collected in 2019 using a cross-sectional survey design. Measures included participants’ demographic characteristics, sleep quality using the Pittsburg Sleep Quality Index (PSQI), drug use, depression using the Patient Health Questionnaire-9 (PHQ-9), and suicidality. After excluding participants with missing information for sleep quality, a total of 555 students remained for the analysis. Our bivariate analysis found that …


Predicting Self-Esteem And Depressive Symptoms From Social Skills In Youth With And Without Autism Spectrum Disorder, Emma Wilkinson Dec 2021

Predicting Self-Esteem And Depressive Symptoms From Social Skills In Youth With And Without Autism Spectrum Disorder, Emma Wilkinson

Legacy Theses & Dissertations (2009 - 2024)

Youth with autism spectrum disorder (ASD) are at increased risk for low self-esteem and depressive symptomatology. Poor social skills may be associated with depression and self-esteem in ASD populations, yet these relationships remain understudied. Previous studies are limited by lack of comparison between youth and parent report of social skills and lack of comparisons to clinically relevant samples. This study seeks to compare predictive relationships between parent and youth-reported social skills, self-esteem, and depressive symptoms across youth with ASD and youth with similar clinical vulnerabilities. Hierarchal regression analyses revealed that youth-reported social skills account for significant variance in self-esteem, parent-reported …


The Association Between Depression And Anxiety With Covid-19 Outcomes., Erica Miller Dec 2021

The Association Between Depression And Anxiety With Covid-19 Outcomes., Erica Miller

Electronic Theses and Dissertations

Previous studies have shown that mental disorders affect COVID-19 mortality. This study investigated the effect of depression and/or anxiety on COVID-19 outcomes. Depression/anxiety was defined by actively taking medication and/or diagnosis. The outcomes were ICU admission; ventilation; mortality; and time to mortality. Of 698 hospitalized patients, there were 204 (29%) defined to have either depression or anxiety. There were 109 deaths, and of those, 52 (48%) were diagnosed with depression/anxiety. Multivariable logistic regression and Cox proportional hazards models were used to examine associations. ICU admission and ventilation were not significantly associated with depression/anxiety. Depression/anxiety was associated with mortality (OR: 1.84, …


Neuroimaging Depression Risk In A Sample Of Never-Depressed Children, Matthew R. J. Vandermeer Nov 2021

Neuroimaging Depression Risk In A Sample Of Never-Depressed Children, Matthew R. J. Vandermeer

Electronic Thesis and Dissertation Repository

Children of mothers with a history of depression are at significantly higher risk for developing depression themselves. Although numerous mechanisms explaining this relationship have been proposed (Goodman & Gotlib, 1999), relatively little is known about the neural substrates of never-depressed children’s depression risk. Of the few studies that have used neuroimaging techniques to characterize risk-based differences in children’s neural structure, function, and functional connectivity, most have used samples that include participants with a personal history of depression or older samples (i.e., past the typical age of onset for depressive disorders). These approaches limit what can be determined regarding whether findings …


The Impact Of Interruptions In Gender-Affirming Medical Care During Covid-19 On Anxiety And Depression Among Trans And Non-Binary People In Canada: A Longitudinal Study, Sara Todorovic Oct 2021

The Impact Of Interruptions In Gender-Affirming Medical Care During Covid-19 On Anxiety And Depression Among Trans And Non-Binary People In Canada: A Longitudinal Study, Sara Todorovic

Electronic Thesis and Dissertation Repository

Background. Transgender and non-binary (TGNB) populations experience disproportionally high levels of anxiety and depression; it is imperative we investigate how the COVID-19 pandemic may have impacted the mental health of TGNB communities. Methods. Among a Canadian sample of TGNB persons aged >=15 years, we used multiple linear regression to examine whether interruptions in gender-affirming care were associated with anxiety and depression, and whether that effect was modified by pre-pandemic mental health. Results. Anxiety and depression levels were high both pre-pandemic and during the pandemic. Approximately a quarter of TGNB persons experienced interruptions in hormonal care. After adjusting for confounders, there …


Measuring The Development Of Depression In A Long-Term Care Facility, Cantrell Anderson Oct 2021

Measuring The Development Of Depression In A Long-Term Care Facility, Cantrell Anderson

Doctoral Projects

Depression is a severe global health problem (Almond, 2009; Brewis et al., 2018; Liu et al., 2019). According to the World Health Organization [WHO] (2020), depression is a problem that more than 264 million people suffer from. In comparison to older adults in the community, depression rates are significantly higher among older adults in long-term care. The treatment of older adults in long-term care is challenging. There are several risk factors that contribute to depression in this population, however, they are still not clear.

The purpose of this Doctor of Nursing Practice (DNP) project was to measure the development of …


Role Of Cortisol In The Development Of Post-Traumatic Stress And Dysphoria, Devi Jayan Oct 2021

Role Of Cortisol In The Development Of Post-Traumatic Stress And Dysphoria, Devi Jayan

Dissertations (1934 -)

Exposure to a traumatic event is a significant predictor for the development of posttraumatic stress disorder (PTSD) and depression. Identification of specific risk factors for PTSD and depression after trauma exposure has been challenging due to comorbid and heterogeneous presentations of these conditions. Pre-existing research demonstrates reduced cortisol response (hypocortisolism) in chronic PTSD and an exaggerated cortisol response (hypercortisolism) in depression. The current longitudinal study examined cortisol response following a traumatic injury as a potential biomarker for deciphering specific risk for PTSD, depression, and PTSD depression comorbidity. Saliva samples for cortisol assay (post-injury cortisol) were collected from 172 trauma survivors …


The Effect Of Postpartum Depression Screening Education For Postpartum Nurses, Shecarra S. Cook Oct 2021

The Effect Of Postpartum Depression Screening Education For Postpartum Nurses, Shecarra S. Cook

Electronic Theses and Dissertations

Depression affects about 13% of pregnant women and about 10% of women after childbirth. Some cases are so severe, the mother may even commit suicide. If left untreated, postpartum depression (PPD) affects both the mother’s and the infant’s health as well as their quality of life. The gap in clinical practice is that currently, patients only complete a postpartum depression screening tool during their 6-week follow-up appointment with their OB/GYN, leaving a gap in PPD detection and care during the immediate postpartum period. Postpartum nurses are not usually given specialized training in postpartum depression. The purpose of this study was …


Chronic Pain Following Musculoskeletal Injuries: Where Do Familial Factors, Depression, And Distress Fit In?, Shirin Modarresi Sep 2021

Chronic Pain Following Musculoskeletal Injuries: Where Do Familial Factors, Depression, And Distress Fit In?, Shirin Modarresi

Electronic Thesis and Dissertation Repository

Background: Currently, there is a paucity of effective therapeutic options for chronic pain. A better understanding of the factors that can contribute to chronic pain development and maintenance can lead to more informed prevention and management strategies.

Purpose: The driving force for this thesis comes from the biopsychosocial model of pain. The main purpose was to investigate the contribution of various psychosocial factors to chronic pain with the following objectives: 1) to systematically review the literature on the existence of a familial sub-type of complex regional pain syndrome (fCRPS); 2) CRPS can follow injuries such as distal radius fractures (DRFs), …


Study Of Primary Cilia In Early Development, Pharmacology, And Brainwave Activity., Matthew Roderick Strobel Sep 2021

Study Of Primary Cilia In Early Development, Pharmacology, And Brainwave Activity., Matthew Roderick Strobel

Doctoral Dissertations

The primary cilium is a unique cellular organelle that emanates from the mother centriole and extends out of the plasma membrane of nearly every mammalian cell. While originally believed to be a vestigial appendage, the cilium is now known to be a signaling hub where various intercellular communication pathways intersect to regulate morphogenesis, proliferation, polarity, differentiation, and homeostasis. Due to their importance in regulating cellular functions the cilium has become a growing focus of biomedical research as it has been linked to at least 35 human developmental disorders which have been termed ciliopathies. In the nervous system, primary cilia regulate …


An Evaluation Of An Integrated Multidisciplinary Early Identification And Triage Of College Students At Risk For Anxiety And Depression, Sarah J. Templeton Sep 2021

An Evaluation Of An Integrated Multidisciplinary Early Identification And Triage Of College Students At Risk For Anxiety And Depression, Sarah J. Templeton

Electronic Theses and Dissertations

College students across the U.S. are experiencing an increasing prevalence of mental health concerns, such as anxiety and depression. Suicide is currently the second most common cause of death among U.S. college students. At the project site, the university health services report that mental health issues significantly impact the students’ academic progress, contributing to poor performance, inability to complete assignments, and sometimes forces attrition. Campus providers traditionally respond when students approach, often at the point of crisis or exacerbation. This Doctor of Nursing Practice (DNP) project evaluated the impact of a pilot program using an interdisciplinary approach to universal proactive …


Parent And Child Language Profiles And Their Family And Clinical Predictors, Jesus Eduardo Solano-Martinez Aug 2021

Parent And Child Language Profiles And Their Family And Clinical Predictors, Jesus Eduardo Solano-Martinez

College of Science and Health Theses and Dissertations

A large number of households in the United States include linguistic minority and immigrant parents. These include parents of Latinx backgrounds and their children who have varying levels of English and Spanish proficiency. Research is needed to examine the nature of parent-child language proficiency patterns and differences and their links to family processes and mental health. To address this gap, a sample of 294 Latinx parent-child dyads of predominantly low-income and immigrant backgrounds were interviewed and reported their English and Spanish language proficiency levels. Latent Profile Analysis (LPA) uncovered four parent-child language profiles including three in which there was a …


Measuring Allostatic Load In An Urban Adolescent Sample: The Profile And Role Of Biomarker Dysregulation In Depression Outcomes, Heather Marshall Aug 2021

Measuring Allostatic Load In An Urban Adolescent Sample: The Profile And Role Of Biomarker Dysregulation In Depression Outcomes, Heather Marshall

College of Science and Health Theses and Dissertations

Accumulated, chronic stress exposure is well established as a precursor for allostatic load (AL). Both stress exposure and AL have been associated with depression in the existing literature. While many studies have focused on biomarkers representative of various physiological systems, a clear understanding of how physiological AL results in depression is yet unclear. Further, variability of hypo- and hypercortisolemic profiles have been associated with depression. A review of the existing literature supports hypocortisolemic profiles in relation to female depression and hypercortisolemic profiles in male depression across both adolescent and adult populations. The function of alpha-amylase (AA) dysregulation within the context …


Rejection Sensitivity, Relationship Quality, And Adjustment In Late-Adolescent Romantic Relationships And Friendships, Laura A. Foster Aug 2021

Rejection Sensitivity, Relationship Quality, And Adjustment In Late-Adolescent Romantic Relationships And Friendships, Laura A. Foster

Electronic Theses and Dissertations

Rejection sensitive (RS) individuals are at greater risk for emotional maladjustment across the lifespan, with consistent links identified with depression and social anxiety. Yet little is known about interpersonal factors that may affect this association for late adolescents, especially with their romantic partners and close friends. The present study examined relationship qualities of support and negative interactions with romantic partners and friends as moderators of the link between RS and internalizing symptoms. Given the differences between male and female social relationships and experiences, these associations were expected to be further moderated by gender, with RS females in poorer quality relationships …


The Effects Of Matched And Mismatched Social Support On Anxious And Depressive Symptoms In Women With Multiple Sclerosis, Elena A. Thomopoulos Aug 2021

The Effects Of Matched And Mismatched Social Support On Anxious And Depressive Symptoms In Women With Multiple Sclerosis, Elena A. Thomopoulos

Seton Hall University Dissertations and Theses (ETDs)

ABSTRACT

There have been many significant findings and contributions to the literature on multiple sclerosis (MS) concerning both physical and mental well-being of individuals who are diagnosed with this illness. While MS is more commonly known now, more than before, there are many obstacles and challenges individuals diagnosed with MS face than people realize. Symptoms that affect individuals with MS are not easily recognized such as fatigue, blurry vision, issues with dexterity, bodily pain, numbness in extremities, and more. Due to the nature of this disease, and many adaptations in life individuals have to make due to their symptoms, studies …


Utilization Patterns Of Community-Based Mental Health Services Among School-Going Adolescent Girls In Southwestern Uganda., William Byansi Aug 2021

Utilization Patterns Of Community-Based Mental Health Services Among School-Going Adolescent Girls In Southwestern Uganda., William Byansi

Arts & Sciences Electronic Theses and Dissertations

ABSTRACT OF THE DISSERTATION

Globally an estimated 20% of children and adolescents experience a disabling mental illness (Belfer, 2008). Mental health disorders are the second leading cause of disease burden and the eleventh leading cause in older adolescents (15-19 years). Yet, children and adolescents are over-represented in low-resourced countries and settings often characterized by violence, wars, diseases, physical and sexual abuse, all of which are associated with poor mental health functioning (Kieling et al., 2011; Naker, 2005). Moreover, in LMICs the treatment gap is about 93% of individuals without access to mental health services with virtually no coverage of evidence-based …


Stigma And Social-Emotional Health In Youth With Learning Differences, Kelsey Maki Aug 2021

Stigma And Social-Emotional Health In Youth With Learning Differences, Kelsey Maki

Doctoral Dissertations

Youth diagnosed with specific learning disorder (SLD) and/or attention deficit hyperactivity disorder (ADHD), defined collectively for the purposes of this study as youth with learning differences, experience poorer social-emotional health outcomes in comparison to their typically developing peers. These youth additionally experience stigma from their peers, teachers, and broader community, which may impact social-emotional health. As a secondary data analysis of a larger study, the present study investigated the role of stigma consciousness alongside demographic variables, self-esteem, and peer relationships in social-emotional health outcomes. Due to the possible differences between youth diagnosed with SLD, ADHD, and comorbid SLD/ADHD, group differences …


Investigating Associations Between Anxiety Sensitivity And Patient Outcomes In A Cardiac Rehabilitation Program: A One Health Approach, Ebuka Osuji Aug 2021

Investigating Associations Between Anxiety Sensitivity And Patient Outcomes In A Cardiac Rehabilitation Program: A One Health Approach, Ebuka Osuji

Electronic Thesis and Dissertation Repository

Cardiac Rehabilitation (CR) is an exercise-based program, aimed at improving ones’ cardiovascular health. A substantial majority of patients referred to CR do not enroll, complete, or achieve clinical targets in the program due to patient-level factors. The objective of this thesis was to investigate relationships between anxiety sensitivity (AnxS) and patient outcomes in CR. Self-reported questionnaires were completed across two time points, with patient information being abstracted from medical records. Stakeholders associated with reducing the burden of AnxS in CR were also identified using snow-ball sampling. Findings suggest that resting diastolic blood pressure is associated with the interrelationships between AnxS, …


What Can An Evolutionary Explanation Bring To The Demarcation Of The Normal From The Pathological In Psychiatry' Nesse's Case Of Depression, Chrysi Malouchou Kanellopoulou Aug 2021

What Can An Evolutionary Explanation Bring To The Demarcation Of The Normal From The Pathological In Psychiatry' Nesse's Case Of Depression, Chrysi Malouchou Kanellopoulou

Philosophy Theses

Randolph Nesse argues that evolutionary theory is the key element in elaborating a valid criterion demarcating the normal from the pathological in psychiatry (Nesse, 2001, 2009, 2015, 2017). By focusing on the application of Nesse’s criterion on the demarcation of normal low mood from pathological depression, I argue – contrary to Nesse’s claims – that evolutionary theory cannot generate a valid criterion from the differentiation of normal low mood states from pathological depression. Indeed, expression in conformity to evolved functions cannot constitute a sufficient condition for normality, as Nesse’s project should imply. Moreover, grounding normality in evolved functions presupposes a …


Queer Lives In Idaho And The Surrounding Region: Impacts Of Anti-Discrimination Laws, High School Environment, And The Covid-19 Pandemic On Mental Health, Ollie Shannon Aug 2021

Queer Lives In Idaho And The Surrounding Region: Impacts Of Anti-Discrimination Laws, High School Environment, And The Covid-19 Pandemic On Mental Health, Ollie Shannon

Boise State University Theses and Dissertations

The experiences of Queer people in the Intermountain-West are under- documented by the scientific community. Suicide is the 10th leading cause of death in the United States. It was responsible for more than 47,500 deaths in 2019. Members of the Queer community have higher rates of suicidal ideation and attempts than the general population. Theoretically, we may predict that people experience negative mental health outcomes under situations of reduced social contact and support or during periods of exclusion by conspecifics. My research explores mental health in the Queer community utilizing data collected in an online survey during the COVID-19 pandemic. …


Depressive Symptoms And Marijuana Outcomes In College Students: The Mediating Role Of Protective Behavioral Strategies For Marijuana, Nicholas Militello Aug 2021

Depressive Symptoms And Marijuana Outcomes In College Students: The Mediating Role Of Protective Behavioral Strategies For Marijuana, Nicholas Militello

Master's Theses

The present study evaluated the sequentially mediating role of protective behavioral strategies for marijuana (PBSM) and marijuana use frequency on the relationships depressive symptoms had with hazardous marijuana use and marijuana-related negative consequences in college students Participants were 338 (50.3% male) undergraduate college students age 18 to 25 (M = 22.10; SD = 1.97) who reported marijuana use in the past 30 days. Participants reported their gender and completed measures of depressive symptoms, PBSM use, marijuana use frequency, marijuana-related negative consequences, and hazardous marijuana use through an online survey from a 2018 project. Depressive symptoms were positively associated with …


Pilot Testing A Survey Instrument To Evaluate Eaat Professionals' Views On The Effects Of Equine-Assisted Activities And Therapies On Hope And Depression In Court-Involved Youth, Emily Stewart Aug 2021

Pilot Testing A Survey Instrument To Evaluate Eaat Professionals' Views On The Effects Of Equine-Assisted Activities And Therapies On Hope And Depression In Court-Involved Youth, Emily Stewart

Animal Science Undergraduate Honors Theses

Equine Assisted Activity and Therapy (EAAT) programs have proven beneficial for individuals with mental, physical and psychological ailments. Only in the last few years have court systems begun to utilize the complex nature of the human-horse relationship to benefit the lives of court-involved youth. Despite its novelty, the few existing studies in this field yield positive results (Frederick et al., 2015). To address the need for further research in this area, a pilot study was conducted. An exploratory survey was given to EAAT professionals to determine their views on the effects of EAAT programs on hope and depression in court-involved …


Preclinical Behavioral Assessment Of Chronic, Intermittent Low-Dose Psilocybin In Rodent Models Of Depression And Anxiety, Harmony I. Risca Aug 2021

Preclinical Behavioral Assessment Of Chronic, Intermittent Low-Dose Psilocybin In Rodent Models Of Depression And Anxiety, Harmony I. Risca

Dissertations

Recent studies have demonstrated the clinical efficacy of psychedelic-assisted psychotherapy for treatment-resistant depression and anxiety. Amidst the overall success of recent clinical trials using a single high dose of psilocybin, anecdotal reports indicate anxiolytic and antidepressant effects following a repeated low dose regimen. As therapeutic outcomes are often tightly intertwined with the individual’s subjective experience, animal models are used as objective measures to investigate the underlying mechanisms responsible for the putative antidepressant/anxiolytic effects of psychedelics. Three rodent models predictive of anxiolytic or antidepressant effects were used to evaluate effects of chronic intermittent low dose (CILD) psilocybin treatment; the Light/Dark conflict …