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Structure Of Unmodified And Pyroglutamylated Amyloid Beta Peptide In Lipid Membranes, Rowan Hassan Jan 2021

Structure Of Unmodified And Pyroglutamylated Amyloid Beta Peptide In Lipid Membranes, Rowan Hassan

Honors Undergraduate Theses

Alzheimer's Disease (AD) is a devastating neurodegenerative disease that is characterized by brain atrophy, neuronal and synaptic loss, cognitive decline, trouble handling activities of daily life, and ultimately leads to death. Worldwide, at least 30 million people suffer from AD, with 5.8 million suffering in the US alone. Despite extensive basic and clinical research, the underlying molecular mechanisms behind AD remain largely unknown. There are four FDA-approved compounds are used for alleviating symptoms but have no curative potency. The first potentially disease-modifying AD drug, aducanumb, was approved by FDA in June 2021. The main histopathological traits of AD are the …


A Woman Of Power: The Leadership Of Speaker Nancy Pelosi, Hannah F. Anton Jan 2021

A Woman Of Power: The Leadership Of Speaker Nancy Pelosi, Hannah F. Anton

Honors Undergraduate Theses

Nancy Pelosi (CA-12) was elected to the House of Representatives in 1987 and was the first female Speaker of the House, originally elected to the position in 2007. Despite the length and significance of her career in the House, there is very little academic literature devoted to the effectiveness of her leadership. In an attempt to fill this research gap, this thesis will raise the following questions; Is Nancy Pelosi an effective Speaker of the House, and has her effectiveness changed significantly over her term as Speaker? For purposes of this research, leadership effectiveness is defined as the Speaker's ability …


Constitutional Camouflage: How Constitutional Methodologies Act As Smoke Screens For Supreme Court Justices, William J. Lijewski Jan 2021

Constitutional Camouflage: How Constitutional Methodologies Act As Smoke Screens For Supreme Court Justices, William J. Lijewski

Honors Undergraduate Theses

The Supreme Court Justices of the United States sit on the highest court of the land. The justices have the ultimate say as to the meaning of the Constitution, and their role could aptly be summarized as interpreters of the Constitution. They decide what the words of the nation's founding document mean and therefore help to determine the rule of law for the social, political, and economic areas of society. To help them analyze the text of the Constitution and decide what it means and subsequently apply it to cases, justices use constitutional methodologies. Constitutional methodologies are algorithms or ways …


Catherine The Great And Her Empire In British And American Newspapers, Arlen B. Cordero Jan 2021

Catherine The Great And Her Empire In British And American Newspapers, Arlen B. Cordero

Honors Undergraduate Theses

This paper explores portrayals of Catherinian Russia in British and American periodicals during her reign, between 1762 and 1796. Catherine II had an incredibly eventful reign as she enacted important domestic reforms, engaged in two major wars with the Ottoman Empire, executed three partitions of the Polish-Lithuanian Commonwealth, and created the League of Armed Neutrality, among other accomplishments. Britain and America equally experienced momentous change during this period, most notably with the American War for Independence. This paper examines how British and American periodicals reacted to the significant events of Catherine's reign using published materials such as news reports, opinion …