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Antimicrobial

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Cationic Polypeptides Contribute To The Anti-Hiv-1 Activity Of Human Seminal Plasma, Julie A. Martellini, Amy L. Cole, Nitya Venkataraman, Gerry A. Quinn, Pavel Svoboda, Bhushan K. Gangrade, Jan Pohl, Ole E. Sorensen, Alexander M. Cole Jan 2009

Cationic Polypeptides Contribute To The Anti-Hiv-1 Activity Of Human Seminal Plasma, Julie A. Martellini, Amy L. Cole, Nitya Venkataraman, Gerry A. Quinn, Pavel Svoboda, Bhushan K. Gangrade, Jan Pohl, Ole E. Sorensen, Alexander M. Cole

Public Health Resources

Mucosal surfaces of the reproductive tract as well as their secretions have important roles in preventing sexual transmission of HIV-1. In the current study, the majority of the intrinsic anti-HIV-1 activity of human seminal plasma (SP) was determined to reside in the cationic polypeptide fraction. Antiviral assays utilizing luciferase reporter cells and lymphocytic cells revealed the ability of whole SP to prevent HIV-1 infection, even when SP was diluted 3200-fold. Subsequent fractionation by continuous flow acid-urea (AU)- PAGE and antiviral testing revealed that cationic polypeptides within SP were responsible for the majority of anti-HIV-1 activity. A proteomic approach was utilized …


Biological Screening Of Vitis Vinifera L. Leaf Fractions, Di̇dem Deli̇orman Orhan, Ni̇lüfer Orhan, Berri̇n Özçeli̇k, Fatma Ergun Jan 2009

Biological Screening Of Vitis Vinifera L. Leaf Fractions, Di̇dem Deli̇orman Orhan, Ni̇lüfer Orhan, Berri̇n Özçeli̇k, Fatma Ergun

Turkish Journal of Biology

The fractions of different polarity, namely chloroform, ethylacetate, n-butanol, and remaining water fractions, were fractionated from an aqueous extract of V. vinifera leaves. The antibacterial, antifungal, antiviral, antioxidant activities, and total phenolic content of these fractions were investigated. The chloroform fraction showed a promising effect against Herpes simplex virus type-1 (HSV-1) and Parainfluenza viruses (PIV). The results indicated that all the fractions were more pronounced against gram-positive bacteria (S. aureus and E. faecalis) than against gram-negative bacteria (E. coli and P. aeruginosa). On the other hand, the fractions showed equal antifungal activity against the genus Candida (C. albicans and C. …


Antimicrobial Activity Of Plant Essential Oils Using Food Model Media: Efficacy, Synergistic Potential And Interaction With Food Components, Jorge Gutierrez, Catherine Barry-Ryan, Paula Bourke Jan 2009

Antimicrobial Activity Of Plant Essential Oils Using Food Model Media: Efficacy, Synergistic Potential And Interaction With Food Components, Jorge Gutierrez, Catherine Barry-Ryan, Paula Bourke

Articles

The aim of this study was to optimise the antimicrobial efficacy of plant essential oils (EOs) for control of Listeria spp. and spoilage bacteria using food model media based on lettuce, meat and milk. The EOs evaluated were lemon balm, marjoram, oregano and thyme and their minimum inhibitory concentrations (MIC) were determined against Enterobacter spp., Listeria spp., Lactobacillus spp., and Pseudomonas spp. using the agar dilution method and/or the absorbance based microplate assay. MICs were significantly lower in lettuce and beef media than in TSB. Listeria strains were more sensitive than spoilage bacteria, and oregano and thyme were the most …


Antibacterial Activities Of Extracts From Some Turkish Endemic Plants On Common Fish Pathogens, Hakan Türker, Arzu Bi̇ri̇nci̇ Yildirim, Fatma Pehli̇van Karakaş, Hi̇lal Köylüoğlu Jan 2009

Antibacterial Activities Of Extracts From Some Turkish Endemic Plants On Common Fish Pathogens, Hakan Türker, Arzu Bi̇ri̇nci̇ Yildirim, Fatma Pehli̇van Karakaş, Hi̇lal Köylüoğlu

Turkish Journal of Biology

Antibacterial activities of 24 alcoholic and aqueous extracts from 8 endemic Turkish plants (Crocus abantensis, Crocus ancyrensis, Galanthus plicatus subsp. byzantinus, Paronychia chionaea, Astragalus gymnolobus, Trifolium pannonicum subsp.elongatum, Eryngium bithynicum, and Convolvulus galaticus) of 7 different families were screened. Antibacterial activity was carried out with 5 different fish pathogens (Aeromonas hydrophila, Yersinia ruckeri, Streptococcus agalactia, Lactococcus garvieae, and Enterococcus faecalis). Crude extracts of endemic plant extracts were applied against the bacteria using the disc diffusion method under in vitro conditions. A. hydrophila was the only inhibited bacteria from all alcoholic and aqueous extracts of C. ancyrensis, G. plicatus, T. pannonicum, …


The Chemical Ecology Of Antarctic Sponges, Kevin J. Peters Jan 2009

The Chemical Ecology Of Antarctic Sponges, Kevin J. Peters

All ETDs from UAB

Sponges were collected from shallow waters along the western Antarctic Peninsula near Palmer Station on Anvers Island. The majority (78%) of the sponges were found to have outer tissues defended against the omnivorous, Antarctic sea star Odontaster validus. Of the species that had outer tissues defended, 62% of them also had internal tissues that inhibited feeding by O. validus. Lipophilic or hydrophilic extracts coated on artificial food pellets were found to be unpalatable for all of the sponge species tested. These data provide evidence that defenses are common survival strategies in sessile macroinvertebrates from Antarctica but that the allocation of …


Antimicrobial Effect Of Yogurt Lactic Acid Bacteria And Muscadine Products On Enterobacter Sakazakii, Weiien Weng Dec 2008

Antimicrobial Effect Of Yogurt Lactic Acid Bacteria And Muscadine Products On Enterobacter Sakazakii, Weiien Weng

Theses and Dissertations

Enterobacter sakazakii has been associated with powdered infant formula outbreaks which caused high mortality rate illnesses in infants in recent years. Current research was mainly focused on searching for natural antimicrobial agents which may be incorporated into baby foods to control this emerging pathogen. Yogurt and muscadine products were used in this study. The antimicrobial effects of yogurt were evaluated on agar plates and in a simulated gastrointestinal model. In the agar spot tests, diluted yogurt sample containing lactic acid bacteria at 106 CFU/mL was antagonistic toward E. sakazakii. However, the antimicrobial effect of yogurt on E. sakazakii in the …


Design And Synthesis Of Carbohydrate Based Derivatives As Antimicrobial Compounds, Aoife Smith Sep 2008

Design And Synthesis Of Carbohydrate Based Derivatives As Antimicrobial Compounds, Aoife Smith

Doctoral

Investigations into the design of analogues of GlcNAc-Ins, the substrate for the enzyme GlcNAc-Ins deacetylase (mshB), a therapeutic target on the pathway to mycothiol biosynthesis in Mycobacterium tuberculosis are described. Initial studies directed towards the design of a substrate analogue were based on the 3-D structure and a proposed mechanism of action of mshB (deduced by Dr. Andrew McCarthy, EMBL). The compounds were designed with the aim to produce an analogue which could better mimic the natural substrate for mshB (GlcNAc-Ins) for crystallisation and mechanistic studies to further improve the knowledge of this enzyme. A series of fatty acid ester …


Steam, Dielectric Heating And Copper Sulfate Treatment Of Inshell Pecans, Mandar Ranchhod Patel Aug 2008

Steam, Dielectric Heating And Copper Sulfate Treatment Of Inshell Pecans, Mandar Ranchhod Patel

Theses and Dissertations

Water and a copper sulfate (CSL) solution at 27, 57 and 88°C; steam pasteurization and dielectric heating were analyzed on their effect in reducing microbial load (APC) and Salmonella Typhimurium on inshell pecans (Carya illinoinensis). The CSL solution (more effective than water alone) reduced APC by 1.5 (300 s), 2 (60 s) and 4.0 (60 s) log CFU/g at 27, 57 and 88°C, respectively; and Salmonella by 3.0 log at 27°C in 60 s. Steam reduced APC by 3.7 log in 180 s and Salmonella by 4.0 log CFU/g in 30 s. Dielectric treatment reduced APC by 3.0 log and …


The Anti-Microbial Efficacy Of Plant Essential Oil Combinations And Interactions With Food Ingredients, Jorge Gutierrez, Catherine Barry-Ryan, Paula Bourke May 2008

The Anti-Microbial Efficacy Of Plant Essential Oil Combinations And Interactions With Food Ingredients, Jorge Gutierrez, Catherine Barry-Ryan, Paula Bourke

Articles

The objective of this study was to evaluate the efficacy of plant essential oils (EOs) in combination and to investigate the effect of food ingredients on their efficacy. The EOs assessed in combination included basil, lemon balm, marjoram, oregano, rosemary, sage and thyme. Combinations of EOs were initially screened against Bacillus cereus, Escherichia coli, Listeria monocytogenes and Pseudomonas aeruginosa using the spot-on-agar test. The influence of varying concentrations of EO combinations on efficacy was also monitored using E. coli. These preliminary studies showed promising results for oregano in combination with basil, thyme or marjoram. The checkerboard method was then used …


Uji Aktivitas Antimikroba Dan Uji Sitotoksik Ekstrak Etanol Akar Tanaman Akar Kucing (Acalypha Indica Linn), Daging Buah Mahkota Dewa (Phaleria Macrocarpa (Sheff) Boerl) Dan Sari Buah Merah (Pandanus Conoideus Lam), Maksum Radji, Ratna Chandra Sari, Atiek Sumiati Apr 2008

Uji Aktivitas Antimikroba Dan Uji Sitotoksik Ekstrak Etanol Akar Tanaman Akar Kucing (Acalypha Indica Linn), Daging Buah Mahkota Dewa (Phaleria Macrocarpa (Sheff) Boerl) Dan Sari Buah Merah (Pandanus Conoideus Lam), Maksum Radji, Ratna Chandra Sari, Atiek Sumiati

Majalah Ilmu Kefarmasian

The antimicrobial activity and cytotoxic effect of ethanol extract of Acalypha indica Linn, Phaleria macrocarpa (Sheff) Boerl and Pandanus conoideus Lam, had been carried out. The results of the research showed that those ethanol extracts had antimi-crobial activities against Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Pseudomonas aeruginosae ATCC 27853 and Candida albicans. The determi-nation of cytotoxic effects of those ethanol extracts by brine shrimp lethality test (BSLT) using Artemia salina Leach showed that LC50 of Acalypha indica Linn, Phaleria macrocarpa (Sheff) Boerl and Pandanus conoideus Lam were 1,279 ug/ml, 0.123 ug/ml and 0.054 ug/ml respectively.


Food Colloids As Carrier Systems For Antimicrobials, Sarisa Suriyarak Jan 2008

Food Colloids As Carrier Systems For Antimicrobials, Sarisa Suriyarak

Masters Theses 1911 - February 2014

Colloidal dispersions such as oil-in-water or water-in-oil emulsions have found widespread use in the food industry. Oil-in-water emulsions consist of three principal components i.e. oil dispersed in the form of droplets, water surrounding the droplets as the continuous phase, and emulsifiers comprising the interface. Because of the complicated interaction among components, it is often difficult to predict the physicochemical properties and final functionalities of emulsions. Nevertheless, the structural and functional features of emulsions allow scientists to create many unique emulsions that may serve as suitable carriers for lipophilic functional compounds. These functional compounds may include antioxidants, flavors, colors and antimicrobials, …


Questioning The Justifiability Of Innovation Protection In Antimicrobial Drugs: A Law And Economics Perspective, Ankur Sood, Vardaan Ahluwalia Jan 2008

Questioning The Justifiability Of Innovation Protection In Antimicrobial Drugs: A Law And Economics Perspective, Ankur Sood, Vardaan Ahluwalia

Northwestern Journal of Technology and Intellectual Property

No abstract provided.


Regulation Of The Lactoperoxidase System In The Airway, Miryam A. Fragoso Dec 2007

Regulation Of The Lactoperoxidase System In The Airway, Miryam A. Fragoso

Open Access Dissertations

The lactoperoxidase (LPO) antimicrobial system has been shown to play an important role in maintaining sterile conditions in several tissues including the mammary gland, the salivary gland, and the airway. The LPO system in the airway consists of the enzyme LPO and its substrates hydrogen peroxide and an anion. LPO catalyzes the oxidation of a halide or pseudohalide ion for example SCN-or I- by hydrogen peroxide producing a product, OSCN- or OI- which have antibacterial, antifungal, and antiviral properties. In order to have a functional antimicrobial system all the components need to be present at appropriate concentrations. The LPO system …


The Antibacterial Properties Of Brookite Phase Titanium Dioxide Nanoparticles Against Methicillin-Resistant Staphylococcus Aureus, Rupal Shah Aug 2007

The Antibacterial Properties Of Brookite Phase Titanium Dioxide Nanoparticles Against Methicillin-Resistant Staphylococcus Aureus, Rupal Shah

All Theses

Staphylococcus aureus (S. aureus), a major human pathogen, is a common cause of infections worldwide due to its high virulence intensity. By adapting to rapidly changing and uniformly hostile environments, strains of S. aureus acquire resistance to antimicrobial agents shortly after their exposure. For example, within a year of its introduction, S. aureus developed resistance to methicillin which triggered the development of other antimicrobial treatments. In spite of the various antibiotics currently used to treat methicillin-resistant S. aureus (MRSA) infections, antimicrobial resistance is an unavoidable consequence due to the selective pressure of antibiotic exposure. Thus, other prevention modalities are warranted …


Colloidal Particles As Antimicrobial Carrier Systems, Dustin W. Carnahan Jan 2007

Colloidal Particles As Antimicrobial Carrier Systems, Dustin W. Carnahan

Masters Theses 1911 - February 2014

The objective of this thesis is to develop a method by which antimicrobials are delivered into a food product as a concentrated dose to the specific area in which the microorganism is growing without interference from the food matrix. More specifically, we plan to achieve this by delivering the antimicrobials nisin and lysozyme attached to nanoparticles and emulsion droplets. We hypothesize that (a) the attachment to a delivery vessel may increase the local concentration of the antimicrobial in the vicinity of the bacterial pathogens and (b) that the size and charge of the nanoparticle following attachment of the antimicrobials will …


Gyra Mutations In Fluoroquinolone Resistant Clostridium Difficile Pcr 027, Denise Drudy, Lorraine Kyne, Rebecca O’Mahony, Séamus Fanning Jan 2007

Gyra Mutations In Fluoroquinolone Resistant Clostridium Difficile Pcr 027, Denise Drudy, Lorraine Kyne, Rebecca O’Mahony, Séamus Fanning

Articles

No abstract provided.


Evaluating The Effect Of Two Commercial Antimicrobial Products On Salmonella Spp. In The Aquatic Habitat Of The Red-Eared Slider Turtle (Trachemys Scripta Elegans), Trevor Theadore Zachariah Jan 2007

Evaluating The Effect Of Two Commercial Antimicrobial Products On Salmonella Spp. In The Aquatic Habitat Of The Red-Eared Slider Turtle (Trachemys Scripta Elegans), Trevor Theadore Zachariah

LSU Master's Theses

Turtle-associated salmonellosis was recognized as a public health concern in the 1960’s, particularly due to an increase in the incidence of disease among children. In response to the public health threat, the United States Food and Drug Administration (FDA) implemented regulations in 1975 restricting the sale of turtle eggs and turtles with a carapace length less than 10.2 cm. Since that time, attempts to eliminate Salmonella from turtles using antibiotics have been unsuccessful and lead to antibiotic resistant strains of Salmonella on turtle farms. Recent work has focused on identifying non-antibiotic products to suppress or eliminate Salmonella and reverse the …


Antimicrobial Properties Of Syringopeptin 25a And Rhamnolipids, Prerak T. Desai May 2006

Antimicrobial Properties Of Syringopeptin 25a And Rhamnolipids, Prerak T. Desai

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The increasing bacterial resistance to available antibiotics requires the search for new antibacterial compounds to be broadened. This study investigated the antimicrobial properties of two secondary metabolites from fluorescent pseudomonads -- syringopeptin 25A, a lipodepsipeptide produced by Pseudomonas syringae pv. syringae, and a rhamnolipid mixture produced by Pseudomonas aeruginosa. The rate of antimicrobial action was determined by monitoring the rate of uptake of propidium iodide during exposure to the compounds. Inhibition was also confirmed by the microbroth dilution method to determine the MI Cs. Both the compounds inhibited growth of Gram-positive organisms, including Mycobacterium smegmatis, staphylococci, and …


Antimicrobial Effects Of Copper And Brass Ions On The Growth Of Listeria Monocytogenes At Different Temperatures, Ph And Nutrients, Aisha Abushelaibi Jan 2005

Antimicrobial Effects Of Copper And Brass Ions On The Growth Of Listeria Monocytogenes At Different Temperatures, Ph And Nutrients, Aisha Abushelaibi

LSU Doctoral Dissertations

Listeria monocytogenes has been recognized as a human pathogen since 1929. This pathogen is found in many foods and listeriosis infections affect approximately 2,500 people in the United States each year, according to the Centers for Disease Control and Prevention. Of those infected with L. monocytogenes approximately 500 die as a result of the illness. Listeria monocytogenes is a bacterium, commonly found in water, soil, plant material, animals and human. Today, different methods are used by food manufacturers, to reduce the risk of Listeria monocytogenes, such as antimicrobial agents, heating, irradiation, and fermentation. The ability of the bacteria to grow …


Antimicrobial Effect Of Cetylpyridinium Chloride Against Listeria Monocytogenes Growth On The Surface Of Raw And Cooked Shrimp, Tracie Michelle Dupard Jan 2005

Antimicrobial Effect Of Cetylpyridinium Chloride Against Listeria Monocytogenes Growth On The Surface Of Raw And Cooked Shrimp, Tracie Michelle Dupard

LSU Master's Theses

Listeria monocytogenes has emerged as a major foodborne pathogen for the seafood industry due to its psychrotrophic nature and its ubiquitous presence. It has been isolated from soil, sewage, dead vegetative matter, aquatic environments, fecal material, fish, crustaceans, and domesticated animals. As a result, L. monocytogenes has been responsible for several shrimp recalls and has been epidemiologically linked to human listeriosis. Fresh seafood products are highly perishable and their shelf-life is limited by microbiological spoilage. Therefore, when pathogenic microorganisms are involved, it poses a health threat to the general public. The situation is further complicated because seafood processing plants are …


Pharmacokinetics Of Once-Daily Amikacin In Healthy Foals And Therapeutic Drug Monitoring In Hospitalized Equine Neonates, Erica Paige Bucki, Steeve Giguère, Margo Macpherson, Rachel E. Davis Sep 2004

Pharmacokinetics Of Once-Daily Amikacin In Healthy Foals And Therapeutic Drug Monitoring In Hospitalized Equine Neonates, Erica Paige Bucki, Steeve Giguère, Margo Macpherson, Rachel E. Davis

Faculty Publications

The objectives of this study were to investigate the pharmacokinetics of once-daily amikacin in healthy neonates, to determine amikacin concentrations in hospitalized foals, and to determine the minimum inhibitory concentrations (MICs) of amikacin against gram-negative isolates from blood cultures in septic foals. Median half-life, clearance, and volume of distribution of amikacin in healthy 2- to 3-day-old foals after administration of an intravenous bolus of amikacin (25 mg/kg) were 5.07 hours (4.86-5.45 hours), 1.82 mL/min/kg (1.35-1.97 mL/min/kg), and 0.785 L/kg (0.638-0.862 L/kg), respectively. Statistically significant (P or = 3 microg/mL between the 2 groups. An initial dose at 25 mg/kg is …


Antimicrobial Utilization In Nosocomial-Infected Patients At Ratchaburi Hospital(การใช้ยาต้านจุลชีพในผู้ป่วยโรคติดเชื้อในโรงพยาบาลที่โรงพย..., Sarinee Krittiyanunt, Wundee Khumyoung Jan 2004

Antimicrobial Utilization In Nosocomial-Infected Patients At Ratchaburi Hospital(การใช้ยาต้านจุลชีพในผู้ป่วยโรคติดเชื้อในโรงพยาบาลที่โรงพย..., Sarinee Krittiyanunt, Wundee Khumyoung

The Thai Journal of Pharmaceutical Sciences

The objectives of this descriptive study were to study the antimicrobial utilization, type and susceptibility of pathogens, and drug therapy problems (DTPs) in nosocomia-infected patients at Ratchaburi hospital from August 1st to December 31st, 2002. Two...


Synthesis And Antimicrobial Testing Of Some Flavonylsulfonamide Derivatives, Gülgün Ayhan Kilcigi̇l, Oya Bozdağ Dündar, Rahmi̇ye Ertan, Nurten Altanlar Jan 2003

Synthesis And Antimicrobial Testing Of Some Flavonylsulfonamide Derivatives, Gülgün Ayhan Kilcigi̇l, Oya Bozdağ Dündar, Rahmi̇ye Ertan, Nurten Altanlar

Turkish Journal of Chemistry

Six new 4-amino-N-heteroaryl,N-[(2-phenyl-4H-1-benzopyran-4- oxo-6-yl)metil]benzensulfonamide derivatives, (3a-3f) were prepared by reacting 6-bromomethylflavone with the corresponding sulfonamide derivatives and their antimicrobial activities against Escherichia coli were evaluated. All of the compounds exhibited better activity (except compound 3c) than the corresponding sulfonamide derivatives.


Coated-Products With Potent Anti-Hiv And Antimicrobial Properties, George Digenis, Alexander G. Digenis Feb 1996

Coated-Products With Potent Anti-Hiv And Antimicrobial Properties, George Digenis, Alexander G. Digenis

Pharmaceutical Sciences Faculty Patents

A composition which has potent anti-HIV activity. The composition is a high energy coprecipitate of nonoxynol-9 oligomers, polyvinyl-pyrrolidone (PVP) and iodine or PVP-I and shows a pronounced synergistic, anti-HIV effect between the compounds of the composition. The invention also includes paper and plastic products coated with the composition of the invention.


Characterization Of Microorganisms From The Deep Subsurface That Produce Antimicrobial Substances, Michael Victor Staudaher Jan 1996

Characterization Of Microorganisms From The Deep Subsurface That Produce Antimicrobial Substances, Michael Victor Staudaher

UNLV Retrospective Theses & Dissertations

A group of 95 actinomycete-like bacterial isolates were obtained from the deep subsurface at the Nevada Test Site. These isolates were screened for the ability to inhibit the growth of selected challenge organisms. A subset of 12 isolates were found to produce antibacterial substances during their growth and were termed bioactive. It was hypothesized that because the isolation source was solid rock, some of the bioactive isolates would require the presence of a surface in order to make antibiotic substances, and that some of these isolates would fail to produce antibiotics when grown in broth culture alone. It was further …


The Morphological Effects Of Two Antimicrobial Peptides, Hecate-1 And Melittin, On Escherichia Coli, William G. Henk, William J. Todd, Frederick M. Enright, Pamela S. Mitchell Jun 1995

The Morphological Effects Of Two Antimicrobial Peptides, Hecate-1 And Melittin, On Escherichia Coli, William G. Henk, William J. Todd, Frederick M. Enright, Pamela S. Mitchell

Scanning Microscopy

The effects of the 26 amino acid, cationic, amphipathic, antibacterial peptide melittin and hecate-1, a 23 amino acid analog of it, on the gram negative bacterium Escherichia coli were investigated using scanning electron microscopy (SEM), transmission electron micros-copy (TEM), and freeze-fracture. Both peptides killed virtually all bacteria at the peptide concentration and cell density used. TEM and SEM revealed aggregates of bacteria entangled with material extruded from the bacterial surfaces. SEM revealed irregular bacterial surfaces with bleb-like projections. TEM and freeze-fracture indicate that the bacterial inner and outer membranes, as well as the peptidoglycan layer between, were extensively damaged. The …


The Development Of Dermatological Products From Some Thai Medicinal Plants; Part I. Family Labiatae, Siriporn Okonogi, Yanee Pongpaibul, Isamu Murakoshi, Toshikazu Sekine Jan 1993

The Development Of Dermatological Products From Some Thai Medicinal Plants; Part I. Family Labiatae, Siriporn Okonogi, Yanee Pongpaibul, Isamu Murakoshi, Toshikazu Sekine

The Thai Journal of Pharmaceutical Sciences

A comparative study of antimicrobial activities of Coleus amboinicus (I), Anisomeles indica (II), Ocimum sanctum (III), Ocimum basilicum (IV), and Mentha merdinah (V) have been carried out. The ethanol extracts and the essential oils obtained from these ...


G85-748 Prevention And Control Of Swine Dysentery, Gerald E. Duhamel, Alex Hogg, Barbara E. Straw Jan 1985

G85-748 Prevention And Control Of Swine Dysentery, Gerald E. Duhamel, Alex Hogg, Barbara E. Straw

University of Nebraska-Lincoln Extension: Historical Materials

This NebGuide describes the causes and symptoms of swine dysentery and offers management recommendations and treatment procedures for its prevention and control.

Swine dysentery is a highly contagious disease of growing and finishing pigs. First described in Indiana in 1921, it has been called black scours, bloody scours, and vibrionic dysentery.

Swine dysentery causes important financial losses because of reduced feed efficiency and lower weight gain, costs of medication and additional animal care, and death. Substantial costs may result from loss of sales of breeding stock, or depopulation when necessary. Serpula (Treponema) hyodysenteriae, a spiral bacterium, is the cause …