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Erythrocytes And Vascular Function: Oxygen And Nitric Oxide, Christine C. Helms, M. T. Gladwin, Daniel B. Kim-Shapiro

Physics Faculty Publications

Erythrocytes regulate vascular function through the modulation of oxygen delivery and the scavenging and generation of nitric oxide (NO). First, hemoglobin inside the red blood cell binds oxygen in the lungs and delivers it to tissues throughout the body in an allosterically regulated process, modulated by oxygen, carbon dioxide and proton concentrations. The vasculature responds to low oxygen tensions through vasodilation, further recruiting blood flow and oxygen carrying erythrocytes. Research has shown multiple mechanisms are at play in this classical hypoxic vasodilatory response, with a potential role of red cell derived vasodilatory molecules, such as nitrite derived nitric oxide and …

Adrenergic Receptor Expression On Raw264.7 Macrophages, Lindsay Ward

Honors Theses

In this study, AR surface expression patterns and regulation via AR-catecholamine interactions were characterized. Macrophage function was shown to be regulated by catecholamines through both Alpha- and Beta-ARs, as evidenced by corresponding alterations in cytokine production. Treatment of activated macrophages with NE, a general catecholamine, or fomoterol, a P-AR agonist, produced significant decreases in TNF and IL-6 secretion. The effecis of clonidine, an Alpha-AR agonist, produced less consistent results, but clonidine-mediated enhancement of cytokine secretion appears to be mediated by Alpha-AR signaling. LPS was shown to noticeably change the surface expression ofboth types of ARs in RAW264.7 macrophages. However, NE …

The Effect Of Different Warm-Downs On Heart Rate Recovery And Muscular Lactic Acid Removal, Alison Jean Perkins

Honors Theses

Competitive swimmers and coaches have had varying ideas about what exercises constitute an appropriate warm-down. However, there is much agreement about what a warm-down should achieve. A good warm-down should do three things. First, a warm-down should be successful in returning the swimmer's elevated heart rate to the resting heart rate level in a relatively short period of time. Second, the warm-down should flush lactic acid out of the muscles as quickly as possible, and restore blood lactate to baseline levels. Finally the warm-down should contribute to improved athletic performances.

In this experiment, it was expected that a decreasing intensity …

The Effect Of Two Exercise Programs On Positional Kinesthetic Awareness In College Varsity Swimmers, Brenda Dianne Glascock

Master's Theses

The following study was undertaken to determine if Standard and Kinesthetic swimming training would produce an effect on positional kinesthetic awareness of male competitive swimmers at the college level. It was hoped both methods would produce a positive effect, but that Kinesthetic training would prove superior.

The Effects Of Coelomic Fluid And Isotonic Homogenates Of The Freshwater Bryozoan Lophopodella Carteri On Fish Tissue, Roger H. Meacham

Master's Theses

A study was made to determine if fish tissue was poisoned by the coelomic fluid extracted from the common coelomic cavity of colonies of the freshwater bryozoan, Lophopodella carteri (Hyatt). Additional studies were made of fish tissues, in vivo and in vitro, when exposed to homogenates of crushed colonies of L. carteri in isotonic medium.

The fish exposed to the coelomic fluid did not show any signs of respiratory distress and therefore the poisonous quality must be located elsewhere in the bryozoan. The homogenates were determined to be poisonous as fishes exposed to a 3.0% solution were killed within an …

Blood Oxygen Capacity Of Birds, J. R. Powell

Master's Theses

Avian blood oxygen capacity (BOC: Vol. %) was measured by a modified Roughton - Scholander syringe method with regard to parameters of body weight and sex. Two samples, collected from the Richmond vicinity, were investigated: the domestic pigeon (Columba livia Gmelin) and 25 other bird species.

A Comparison Of The Effects Of 23 Hour Food Deprivation And 23 Hour Water Deprivation On The Weight And Intake Of The Albino Rat, Otis Byron Ward

Master's Theses

The present study is designed to make a direct comparison of food and water deprivation schedules both in terms of the animals' adjustment to the schedules and the relative effects of the two schedules on several weight and intake measures. The three groups used are: a control group, a 2) hour food deprivation schedule group, and a 23 hour water deprivation schedule group. The groups will be compared over a period of 50 days in terms of body weight, weight loss and gain, and food and water intake.

The Effects Of Water Deprivation On The Body Weight, Food Intake And Water Intake Of The Albino Rat, Kenneth A. Blick

Master's Theses

A survey of the literature reveals a substantial body of research concerned with the effects of food and/or water deprivation on body weight, food and water intake, and activity of the albino rat. This research is important because many psychological experiments, particularly those studies in the field of animal learning in which motivation is induced by the use of a nutritional maintenance schedule, require some measurement of performance on consecutive days during which the rats are in a motivational state.