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Prevalence Of Pretransition Disordering In The Rutile-To-Cacl2 Phase Transition Of Geo2, G. Alexander Smith, Daniel Schacher, Jasmine K. Hinton, Daniel Sneed, Changyong Park, Sylvain Petitgirard, Keith V. Lawler, Ashkan Salamat Oct 2021

Prevalence Of Pretransition Disordering In The Rutile-To-Cacl2 Phase Transition Of Geo2, G. Alexander Smith, Daniel Schacher, Jasmine K. Hinton, Daniel Sneed, Changyong Park, Sylvain Petitgirard, Keith V. Lawler, Ashkan Salamat

Physics & Astronomy Faculty Research

The ability to tailor a material's electronic properties using density driven disordering has emerged as a powerful route to materials design. The observation of anomalous structural and electronic behavior in the rutile to CaCl2 phase transition in SnO2 led to the prediction that such behavior is inherent to all oxides experiencing such a phase transition sequence [Smith et al., J. Phys. Chem. Lett. 10, 5351 (2019)1948-718510.1021/acs.jpclett.9b01633]. Here, the ultrawide band gap semiconductor GeO2 is confirmed to exhibit anomalous behavior during the rutile to CaCl2 phase transition. A phase pure rutile GeO2 sample synthesized under high-pressure, high-temperature conditions is probed using …


Associations Of Diet With Cardiometabolic And Inflammatory Profiles In Pregnant Women At Risk For Metabolic Complications, Kataryna Jaworsky, Jeffrey L. Ebersole, Petar Planinic, Arpita Basu Oct 2021

Associations Of Diet With Cardiometabolic And Inflammatory Profiles In Pregnant Women At Risk For Metabolic Complications, Kataryna Jaworsky, Jeffrey L. Ebersole, Petar Planinic, Arpita Basu

Dental Medicine Faculty Publications

Dietary intakes play an important role in the development of metabolic complications during pregnancy. While reported observational studies reveal an inverse association of healthy diets with weight gain, gestational diabetes, and hypertensive complications during pregnancy, there is a paucity of studies conducted among women of specific ethnicities vulnerable to higher risks of pregnancy complications. This is a secondary cross sectional analysis using baseline data from a previously reported clinical trial. We aim to identify associations of maternal habitual dietary intakes with cardiometabolic risks and inflammatory profiles in primarily African American (AA) and Hispanic women in the first half of pregnancy. …


Complete Genome Sequences Of Cluster A6 And Cluster G1 Mycobacterium Smegmatis Phages Hoot And Jolene, Jon Thompson, Asli Özdemir, Arsen M. Topchyan, Maxwell Torosian, Victoria Z. Thymianos, Angelica Eagle, Juliana Mccormick, Leon Kyle G. Boyles, Azucena A. Benito, Kurt Regner, Christy Strong, Philippos K. Tsourkas Oct 2021

Complete Genome Sequences Of Cluster A6 And Cluster G1 Mycobacterium Smegmatis Phages Hoot And Jolene, Jon Thompson, Asli Özdemir, Arsen M. Topchyan, Maxwell Torosian, Victoria Z. Thymianos, Angelica Eagle, Juliana Mccormick, Leon Kyle G. Boyles, Azucena A. Benito, Kurt Regner, Christy Strong, Philippos K. Tsourkas

Life Sciences Faculty Research

We present the complete genome sequences of Mycobacterium smegmatis phages Hoot and Jolene, isolated in Las Vegas, NV. The phages were isolated and annotated by students enrolled in an undergraduate research course at the University of Nevada, Las Vegas. Hoot is a cluster A6 mycobacteriophage, while Jolene is in cluster G1.


Population Growth In Mountain West Cities And Suburbs, 2010-2020, Dielle T. Telada, William E. Brown Jr. Oct 2021

Population Growth In Mountain West Cities And Suburbs, 2010-2020, Dielle T. Telada, William E. Brown Jr.

Cities & Metros

COVID-19 altered population growth trends within large cities and the relative growth of cities and suburbs within the nation’s largest metropolitan areas. Brookings senior fellow William H. Frey suggests “that most big cities with populations exceeding 250,000 experienced lower population growth in the year the pandemic began than in the previous year.” This Fact Sheet examines annual growth rates within selected Mountain West metros and suburbs from 2010 and 2020.


Streaming Instability With Multiple Dust Species-Ii. Turbulence And Dust-Gas Dynamics At Non-Linear Saturation, Chao-Chin Yang, Zhaohuan Zhu Oct 2021

Streaming Instability With Multiple Dust Species-Ii. Turbulence And Dust-Gas Dynamics At Non-Linear Saturation, Chao-Chin Yang, Zhaohuan Zhu

Physics & Astronomy Faculty Research

The streaming instability is a fundamental process that can drive dust-gas dynamics and ultimately planetesimal formation in protoplanetary discs. As a linear instability, it has been shown that its growth with a distribution of dust sizes can be classified into two distinct regimes, fast-and slow-growth, depending on the dust-size distribution and the total dust-To-gas density ratio . Using numerical simulations of an unstratified disc, we bring three cases in different regimes into non-linear saturation. We find that the saturation states of the two fast-growth cases are similar to its single-species counterparts. The one with maximum dimensionless stopping time τs,max = …


A Protocol And Novel Tool For Systematically Reviewing The Effects Of Mindful Walking On Mental And Cardiovascular Health, Dustin W. Davis, Bryson Carrier, Brenna Barrios, Kyle Cruz, James W. Navalta Oct 2021

A Protocol And Novel Tool For Systematically Reviewing The Effects Of Mindful Walking On Mental And Cardiovascular Health, Dustin W. Davis, Bryson Carrier, Brenna Barrios, Kyle Cruz, James W. Navalta

Kinesiology and Nutrition Sciences Faculty Publications

To our knowledge, no published systematic review has described the effects of mindful walking on mental and cardiovascular health. We have aimed to fill this gap by first establishing our systematic review protocol. Our protocol was adapted from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and is registered in PROSPERO (Registration Number: CRD42021241180). The protocol is described step-by-step in this paper, which we wrote to achieve three objectives: to adhere to the best practices stated in the PRISMA guidelines, to ensure procedural transparency, and to enable readers to co-opt our protocol for future systematic reviews on mindful …


Perceptions Of Dental Undergraduates Towards Online Education During Covid-19: Assessment From India, Nepal And Sri Lanka, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, Rajlakshmi Banerjee, Rasika Manori Jayasinghe, Dhanushka Leuke Bandara, Navin Agrawal, Vimmi Singh Oct 2021

Perceptions Of Dental Undergraduates Towards Online Education During Covid-19: Assessment From India, Nepal And Sri Lanka, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, Rajlakshmi Banerjee, Rasika Manori Jayasinghe, Dhanushka Leuke Bandara, Navin Agrawal, Vimmi Singh

School of Medicine Faculty Publications

Purpose: The social distancing mandates instituted during COVID-19 pandemic mark the sudden transition in the mode of dental education’s delivery to the virtual instruction. It is vital to assess students’ perceptions towards virtual learning environments, particularly among those gaining education in resource-strained countries. This cross-sectional study aims to assess the perceptions of dental undergraduates towards online education, environment and transferable skills and patient care during COVID-19 in India, Nepal, and Sri Lanka. Materials and Methods: Dental preclinical and clinical undergraduate students from India, Nepal and Sri Lanka were recruited from November 2020 to March 2021 through a 47-item web-based survey …


Single-Cell Rna Sequencing Deconvolutes The In Vivo Heterogeneity Of Human Bone Marrow-Derived Mesenchymal Stem Cells, Zun Wang, Xiaohua Li, Junxiao Yang, Yun Gong, Huixi Zhang, Xiang Qiu, Ying Liu, Cui Zhou, Yu Chen, Jonathan Greenbaum, Liang Cheng, Yihe Hu, Jie Xie, Xucheng Yang, Yusheng Li, Martin R. Schiller Oct 2021

Single-Cell Rna Sequencing Deconvolutes The In Vivo Heterogeneity Of Human Bone Marrow-Derived Mesenchymal Stem Cells, Zun Wang, Xiaohua Li, Junxiao Yang, Yun Gong, Huixi Zhang, Xiang Qiu, Ying Liu, Cui Zhou, Yu Chen, Jonathan Greenbaum, Liang Cheng, Yihe Hu, Jie Xie, Xucheng Yang, Yusheng Li, Martin R. Schiller

Life Sciences Faculty Research

Bone marrow-derived mesenchymal stem cells (BM-MSCs) are multipotent stromal cells that have a critical role in the maintenance of skeletal tissues such as bone, cartilage, and the fat in bone marrow. In addition to providing microenvironmental support for hematopoietic processes, BM-MSCs can differentiate into various mesodermal lineages including osteoblast/osteocyte, chondrocyte, and adipocyte that are crucial for bone metabolism. While BM-MSCs have high cell-to-cell heterogeneity in gene expression, the cell subtypes that contribute to this heterogeneity in vivo in humans have not been characterized. To investigate the transcriptional diversity of BM-MSCs, we applied single-cell RNA sequencing (scRNA-seq) on freshly isolated CD271+ …


Artificial Image Objects For Classification Of Breast Cancer Biomarkers With Transcriptome Sequencing Data And Convolutional Neural Network Algorithms, Xiangning Chen, Daniel G. Chen, Zhongming Zhao, Justin M. Balko, Jingchun Chen Oct 2021

Artificial Image Objects For Classification Of Breast Cancer Biomarkers With Transcriptome Sequencing Data And Convolutional Neural Network Algorithms, Xiangning Chen, Daniel G. Chen, Zhongming Zhao, Justin M. Balko, Jingchun Chen

School of Medicine Faculty Publications

Background: Transcriptome sequencing has been broadly available in clinical studies. However, it remains a challenge to utilize these data effectively for clinical applications due to the high dimension of the data and the highly correlated expression between individual genes. Methods: We proposed a method to transform RNA sequencing data into artificial image objects (AIOs) and applied convolutional neural network (CNN) algorithms to classify these AIOs. With the AIO technique, we considered each gene as a pixel in an image and its expression level as pixel intensity. Using the GSE96058 (n = 2976), GSE81538 (n = 405), and GSE163882 (n = …


Testing Multi-Theory Model (Mtm) In Explaining Sunscreen Use Among Florida Residents: An Integrative Approach For Sun Protection, Manoj Sharma, Matthew Asare, Erin Largo-Wight, Julie Merten, Mike Binder, Ram Lakhan, Kavita Batra Oct 2021

Testing Multi-Theory Model (Mtm) In Explaining Sunscreen Use Among Florida Residents: An Integrative Approach For Sun Protection, Manoj Sharma, Matthew Asare, Erin Largo-Wight, Julie Merten, Mike Binder, Ram Lakhan, Kavita Batra

Environmental & Occupational Health Faculty Publications

Florida residents have the second highest incidence of skin cancer in the nation. Sunscreen usage was found to be the one of the most effective integrative health approaches for reducing risk of skin cancer. Given the limited information on the likelihood of adopting and continuing sunscreen usage behavior, this cross-sectional study aimed to examine the correlates of initiating and sustaining sunscreen usage behavior among Florida dwellers, using the fourth-generation, multi-theory model (MTM) of behavior change. A web-based survey containing 51 questions was emailed to Florida residents aged 18 years or above, who were randomly selected from the state voter file. …


Factors Associated With The Appropriate Use Of Ultra-Broad Spectrum Antibiotics, Meropenem, For Suspected Healthcare-Associated Pneumonia, Nathan Kirsch, Jane Ha, Hee Taik Kang, Tina Frisch, Ji Won Yoo, Craig Grossman, Neema Oroomchi, Hidenobu Shigemitsu, Chad Cross, Mutsumi Kioka Oct 2021

Factors Associated With The Appropriate Use Of Ultra-Broad Spectrum Antibiotics, Meropenem, For Suspected Healthcare-Associated Pneumonia, Nathan Kirsch, Jane Ha, Hee Taik Kang, Tina Frisch, Ji Won Yoo, Craig Grossman, Neema Oroomchi, Hidenobu Shigemitsu, Chad Cross, Mutsumi Kioka

Internal Medicine Faculty Publications

ABSTRACT: Pneumonia is a common disease-causing hospitalization. When a healthcare-associated infection is suspected, antibiotics that provide coverage for multi-drug resistant (MDR) or extended-spectrum beta-lactamase (ESBL) bacteria are frequently prescribed. Limited data is available for guidance on using meropenem as a first-line empiric antimicrobial in hospitalized patients with risk factors for MDR/ESBL bacterial infections. This was a single-center, retrospective study designed and conducted to identify factors associated with positive cultures for MDR/ESBL pathogens in hospitalized patients with suspected healthcare-associated pneumonia.Of the 246 patients, 103 patients (41%) received meropenem. Among patients prescribed meropenem, MDR/ESBL pathogens were detected in only 20 patients (13%). …


Intergenerational Perceptions And Practices In Breastfeeding And Child Feeding Among Quilombola Women In Goiás State, Brazil, Priscila Olin Silva, Muriel Bauermann Gubert, Amanda Kellen Pereira Da Silva, Lucélia Luiz Pereira, Leonor Maria Pacheco Santos, Gabriela Buccini Oct 2021

Intergenerational Perceptions And Practices In Breastfeeding And Child Feeding Among Quilombola Women In Goiás State, Brazil, Priscila Olin Silva, Muriel Bauermann Gubert, Amanda Kellen Pereira Da Silva, Lucélia Luiz Pereira, Leonor Maria Pacheco Santos, Gabriela Buccini

Environmental & Occupational Health Faculty Publications

This exploratory qualitative study aimed to identify sociocultural and intergenerational aspects of perception and practices in child feeding among quilombola women, members of maroon communities in Brazil. A focus group with 12 mothers and another group with four grandmothers of children under five years of age were conducted in a rural quilombola community in the State of Goiás, Brazil. The data were analyzed with thematic content analysis, yielding four central themes and respective subthemes, which were then represented in a socioecological conceptual model with four levels of influence on child feeding as the outcome. Theme 1 dealt with the reasons …


Artificial Intelligence (Ai) Capacity In Mountain West Metros, Olivia K. Cheche, Ally M. Beckwith, William E. Brown Jr. Oct 2021

Artificial Intelligence (Ai) Capacity In Mountain West Metros, Olivia K. Cheche, Ally M. Beckwith, William E. Brown Jr.

Economic Development & Workforce

This fact sheet highlights data on artificial intelligence (AI) growth in Mountain West metropolitan areas over the last several decades, as originally reported by Mark Muro and Sifan Liu from the Brookings Institution’s Metropolitan Policy Program. The Brookings report examines how various metros across the United States contribute towards AI technology creation and business activity.


Novel Insights Into Negative Pressure Wound Healing From An In Situ Porcine Perspective, Jacob G. Hodge, Ashley L. Pistorio, Christopher A. Neal, Hongyan Dai, Jennifer G. Nelson-Brantley, Molly E. Steed, Richard A. Korentager, David S. Zamierowski, Adam J. Mellott Oct 2021

Novel Insights Into Negative Pressure Wound Healing From An In Situ Porcine Perspective, Jacob G. Hodge, Ashley L. Pistorio, Christopher A. Neal, Hongyan Dai, Jennifer G. Nelson-Brantley, Molly E. Steed, Richard A. Korentager, David S. Zamierowski, Adam J. Mellott

School of Medicine Faculty Publications

Negative pressure wound therapy (NPWT) is used clinically to promote tissue formation and wound closure. In this study, a porcine wound model was used to further investigate the mechanisms as to how NPWT modulates wound healing via utilization of a form of NPWT called the vacuum-assisted closure. To observe the effect of NPWT more accurately, non-NPWT control wounds containing GranuFoam™ dressings, without vacuum exposure, were utilized. In situ histological analysis revealed that NPWT enhanced plasma protein adsorption throughout the GranuFoam™, resulting in increased cellular colonization and tissue ingrowth. Gram staining revealed that NPWT decreased bacterial dissemination to adjacent tissue with …


Using Bibliometrics To Evaluate Outcomes And Influence Of Translational Biomedical Research Centers, Kristine M. Bragg, Gwen C. Marchand, Jonathan C. Hilpert, Jeffrey L. Cummings Oct 2021

Using Bibliometrics To Evaluate Outcomes And Influence Of Translational Biomedical Research Centers, Kristine M. Bragg, Gwen C. Marchand, Jonathan C. Hilpert, Jeffrey L. Cummings

Educational Psychology, Leadership, and Higher Education Faculty Research

Introduction. Federal grant funding to support infrastructure development of translational biomedical research centers is a form of public health intervention. Establishing rigorous methods for measuring center success and outcomes is essential to justify continued funding. Methods. Bibliometric data compiled from a 5-year funding cycle of a neurodegeneration and translational neuroscience research center was analyzed using the package bibliometrix for open source software R and the NIH-developed research tool iCite. Results. The research team and their collaborators (n=485) produced 157 grant-citing publications from 2015-2020. The science was produced by small research teams clustered around three main communities of topics: Alzheimer's Disease, …


Initial Acoustoelastic Measurements In Olivine: Investigating The Effect Of Stress On P- And S-Wave Velocities, Taryn K. Traylor, Pamela C. Burnley, M. L. Whitaker Oct 2021

Initial Acoustoelastic Measurements In Olivine: Investigating The Effect Of Stress On P- And S-Wave Velocities, Taryn K. Traylor, Pamela C. Burnley, M. L. Whitaker

Geoscience Faculty Research

It is well known that elasticity is a key physical property in the determination of the structure and composition of the Earth and provides critical information for the interpretation of seismic data. This study investigates the stress-induced variation in elastic wave velocities, known as the acoustoelastic effect, in San Carlos olivine. A recently developed experimental ultrasonic acoustic system, the Directly Integrated Acoustic System Combined with Pressure Experiments (DIASCoPE), was used with the D-DIA multi-anvil apparatus to transmit ultrasonic sound waves and collect the reflections. We use the DIASCoPE to obtain longitudinal (P) and shear (S) elastic wave velocities from San …


Palliative Care And Life-Sustaining/Local Procedures In Colorectal Cancer In The United States Hospitals: A Ten-Year Perspective, Zahra Mojtahedi, Ja Seol Koo, Ji Yoo, Pearl Kim, Hee-Taik Kang, Jinwook Hwang, Moon Kyung Joo, Jay J. Shen Oct 2021

Palliative Care And Life-Sustaining/Local Procedures In Colorectal Cancer In The United States Hospitals: A Ten-Year Perspective, Zahra Mojtahedi, Ja Seol Koo, Ji Yoo, Pearl Kim, Hee-Taik Kang, Jinwook Hwang, Moon Kyung Joo, Jay J. Shen

School of Medicine Faculty Publications

Background: In recent years, palliative care utilization has been increasing while life-sustaining/local procedures have been declining at the end of life. Palliative care utilization widely varies based on tumor type. Limited information is available on inpatient palliative care in colorectal cancer. Aims: This study investigated inpatient palliative care utilization and its association with patient demographics, hospital charges, and procedures among colorectal cancer patients admitted to US hospitals between 2008 and 2017. Receipt of life-sustaining and local procedures and surgeries were also investigated during the ten years. Methods: Data were extracted from the National inpatient sample (NIS) database containing de-identified information …


Nevada Campaign Financing: U.S. House Of Representatives, 2020, Kristian Thymianos, Olivia K. Cheche, William E. Brown Jr. Oct 2021

Nevada Campaign Financing: U.S. House Of Representatives, 2020, Kristian Thymianos, Olivia K. Cheche, William E. Brown Jr.

Elections & Governance

In the 2020 election cycle, Nevada’s U.S. House of Representatives delegation fundraised a combined total of $9,994,636. This fact sheet summarizes the campaign donations and expenditures of these representatives. The data are collected from the Open Secrets website.


Lobectomy For Acquired Lobar Emphysema Months Following Newborn Repair Of Congenital Diaphragmatic Hernia, Mary Froehlich, Lance Horner, Joseph Stathos, Craig Nakamura, Michael G. Scheidler Oct 2021

Lobectomy For Acquired Lobar Emphysema Months Following Newborn Repair Of Congenital Diaphragmatic Hernia, Mary Froehlich, Lance Horner, Joseph Stathos, Craig Nakamura, Michael G. Scheidler

School of Medicine Faculty Publications

Chronic lung disease is a known morbidity of congenital diaphragmatic hernia repair. Although described as a diffuse lung process, we present a case of localized lobar emphysema in a child with a congenital diaphragmatic hernia repair successfully treated with lobectomy. We aim to describe this unique clinical manifestation, detail the intraoperative findings, and describe the successful postoperative course.


Investment Patterns In Mountain West States, Counties, And Nevada Cities 2005-2019, Peter Grema, Zachary Walusek, Katie M. Gilbertson, William E. Brown Jr. Oct 2021

Investment Patterns In Mountain West States, Counties, And Nevada Cities 2005-2019, Peter Grema, Zachary Walusek, Katie M. Gilbertson, William E. Brown Jr.

Economic Development & Workforce

The purpose of this fact sheet is to summarize findings on capital flows across Mountain West states and counties, and within Nevada cities. The “Gauging Investment Patterns across the US” report by the Urban Institute present findings of overall volume of capital deployed, racial equity of investments, and income equity for each respective geographic area. The full report further breaks down these three main categories into 18 other metrics.


Thermal Analysis Of Benzotriazolium Perrhenate And Its Implication To Rhenium Metal, James Louis-Jean, Harry Jang, Andrew J. Swift, Frederic Poineau Sep 2021

Thermal Analysis Of Benzotriazolium Perrhenate And Its Implication To Rhenium Metal, James Louis-Jean, Harry Jang, Andrew J. Swift, Frederic Poineau

Chemistry and Biochemistry Faculty Research

The thermal analysis behavior of C6H6N3[ReO4] was studied by simultaneous thermal gravimetric analysis (TGA) and differential scanning calorimetry (DSC) up to 700 °C under argon. Such analysis afforded rhenium metal, which was characterized by powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), and energy-dispersive X-ray (EDX) spectroscopy. XRD peak broadening due to crystallite size and lattice strain was analyzed by both Williamson-Hall (W-H) and Debye-Scherrer (D-S) methods. Efforts to isolate Re metal from the thermal treatment of benzotriazole (BTA = C6H5N3) with NH4ReO4 and Re2O7 under various atmospheres and temperatures are also reported. The results provide a significant insight into …


Forging Resilience To Hiv/Aids: Personal Strengths Of Middle-Aged And Older Gay, Bisexual, And Other Men Who Have Sex With Men Living With Hiv/Aids, R. Liboro, J. Despres, B. Ranuschio, S. Bell, L. Barnes Sep 2021

Forging Resilience To Hiv/Aids: Personal Strengths Of Middle-Aged And Older Gay, Bisexual, And Other Men Who Have Sex With Men Living With Hiv/Aids, R. Liboro, J. Despres, B. Ranuschio, S. Bell, L. Barnes

Psychology Faculty Research

HIV-positive gay, bisexual, two-spirit, and other men who have sex with men (MSM) have exhibited significant resilience to HIV/AIDS in Canada since the start of the epidemic. Since 2012, most of the research that has been conducted on resilience to HIV/AIDS has utilized quantitative methods and deficits-based approaches, with a preferential focus on the plight of young MSM. In order to address apparent gaps in research on HIV/AIDS resilience, we conducted a community-based participatory research qualitative study that utilized a strengths-based approach to examine the perspectives and lived experiences of HIV-positive, middle-aged and older MSM on their individual attributes that …


Vaccine Hesitancy Within Nevada Counties, June 2021, Kelliann Beavers, Madison Frazee-Bench, William E. Brown Jr. Sep 2021

Vaccine Hesitancy Within Nevada Counties, June 2021, Kelliann Beavers, Madison Frazee-Bench, William E. Brown Jr.

Health

This fact sheet highlights estimated rates of vaccine hesitancy, vaccination rates, the index of social vulnerability, and the level of concern for 17 Nevada counties as of June, 2021. The data are reported in the U.S. Department of Health and Human Services, Assistant Secretary for Planning and Evaluation (ASPE) estimates.


The Costs Of Developing Treatments For Alzheimer’S Disease: A Retrospective Exploration, Jeffrey L. Cummings, Dana P. Goldman, Nicholas R. Simmons-Stern, Eric Ponton Sep 2021

The Costs Of Developing Treatments For Alzheimer’S Disease: A Retrospective Exploration, Jeffrey L. Cummings, Dana P. Goldman, Nicholas R. Simmons-Stern, Eric Ponton

School of Medicine Faculty Publications

Introduction: With the exception of the recent accelerated approval of aducanumab, in over 26 years of research and development (R&D) investment in Alzheimer's disease (AD), only five novel drugs—all for symptomatic treatment only—have reached FDA approval. Here, we estimate the costs of AD drug development during this period in the private sector. Methods: To estimate private R&D funding, we collected information on AD clinical trials (n = 1099; phases 1–4) conducted between January 1, 1995 and June 21, 2021 from various databases. Costs were derived using previously published methodologies and adjusted for inflation. Results: Since 1995, cumulative private expenditures on …


Physical And Mental Disabilities Among The Gender-Diverse Population Using The Behavioral Risk Factor Surveillance System, Brfss (2017–2019): A Propensity-Matched Analysis, Jennifer R. Pharr, Kavita Batra Sep 2021

Physical And Mental Disabilities Among The Gender-Diverse Population Using The Behavioral Risk Factor Surveillance System, Brfss (2017–2019): A Propensity-Matched Analysis, Jennifer R. Pharr, Kavita Batra

Environmental & Occupational Health Faculty Publications

This propensity-matched analysis utilized the publicly available Behavioral Risk Factor Surveillance System (2017–2019) data to compare the burden of disabilities among transgender/non-binary (TGNB) and cisgender groups. The groups were matched (1:1 ratio) on demographic variables using Nearest Neighborhood Matching. Categorical variables were compared among groups using a Chi-square analysis to test differences in the proportions. Multivariate logistic regression analysis was fit to predict the likelihood of the physical and mental disabilities among the TGNB group compared with the cisgender group while controlling for healthcare access factors, income, and employment. Survey weights were included in the model to account for the …


Inferring Tax Compliance From Pass-Through: Evidence From Airbnb Tax Enforcement Agreements, Andrew J. Bibler, Keith F. Teltser, Mark J. Tremblay Sep 2021

Inferring Tax Compliance From Pass-Through: Evidence From Airbnb Tax Enforcement Agreements, Andrew J. Bibler, Keith F. Teltser, Mark J. Tremblay

Economics Faculty Publications

Tax enforcement is especially costly when market participants are difficult to observe. The benefits of enforcement depend crucially on pre-enforcement compliance. We derive an upper bound on pre-enforcement compliance from the pass-through of newly enforced taxes. Using data on Airbnb listings and the platform’s voluntary collection agreements, we find that taxes are paid on, at most, 24% of Airbnb transactions prior to enforcement. We also find that demand for Airbnb listings is inelastic, driving three key insights: the tax burden falls disproportionately on renters, the excess burden is small, and tax enforcement is relatively ineffective at reducing local Airbnb activity.


A Theory-Based Analysis Of Covid-19 Vaccine Hesitancy Among African Americans In The United States: A Recent Evidence, Manoj Sharma, Kavita Batra, Ravi Batra Sep 2021

A Theory-Based Analysis Of Covid-19 Vaccine Hesitancy Among African Americans In The United States: A Recent Evidence, Manoj Sharma, Kavita Batra, Ravi Batra

Environmental & Occupational Health Faculty Publications

African Americans have been disproportionately vaccinated at lower rates, which warrants the development of theory-based interventions to reduce vaccine hesitancy in this group. The fourth-generation theories, e.g., multi-theory model (MTM) of health behavior change, are vital in developing behavioral interventions. Therefore, the current study aims to determine recent trends in COVID-19 vaccination rates and to test the MTM model in predicting the initiation of COVID-19 vaccines among vaccine-hesitant Blacks. A sample of 428 unvaccinated African Americans were recruited through a web-based survey using a 28-item psychometric valid questionnaire. Chi-square, independent-samples-t-test or Welch’s t test, and Pearson’s correlation tests were utilized …


Cdc Social Vulnerability Index (Svi): Nevada Counties, Vanessa Booth, Ally M. Beckwith, Kelliann Beavers, William E. Brown Jr. Sep 2021

Cdc Social Vulnerability Index (Svi): Nevada Counties, Vanessa Booth, Ally M. Beckwith, Kelliann Beavers, William E. Brown Jr.

Demography

This fact sheet highlights how Nevada counties rank on the Social Vulnerability Index (SVI) as defined by the Center for Disease Control (CDC) and the Agency for Toxic Substances and Disease Registry (ASTDR). Socially vulnerable populations are often disproportionately harmed during public health emergencies such as natural disasters and infectious disease outbreaks. The Geospatial Research, Analysis, and Services Program (GRASP) created the CDC/ATSDR Social Vulnerability Index (CDC/ATSDR SCI) to help public health officials and emergency response planners meet community health needs during response and recovery efforts (ATSDR, 2020).


Refugee Arrivals In The Mountain West, 2017-2021, Saha Salahi, William E. Brown Jr. Sep 2021

Refugee Arrivals In The Mountain West, 2017-2021, Saha Salahi, William E. Brown Jr.

Demography

This fact sheet displays data on the influx of refugee arrivals by nation to five Mountain West States: Arizona, Colorado, Nevada, New Mexico, and Utah. Refugee Processing Center data, selected from annual reports and limited to the years 2017-2021, are presented.


Resetting Of Auditory And Visual Segregation Occurs After Transient Stimuli Of The Same Modality, Nathan C. Higgins, Ambar G. Monjaras, Breanne D. Yerkes, David F. Little, Jessica E. Nave-Blodgett, Mounya Elhilali, Joel S. Snyder Sep 2021

Resetting Of Auditory And Visual Segregation Occurs After Transient Stimuli Of The Same Modality, Nathan C. Higgins, Ambar G. Monjaras, Breanne D. Yerkes, David F. Little, Jessica E. Nave-Blodgett, Mounya Elhilali, Joel S. Snyder

Psychology Faculty Research

In the presence of a continually changing sensory environment, maintaining stable but flexible awareness is paramount, and requires continual organization of information. Determining which stimulus features belong together, and which are separate is therefore one of the primary tasks of the sensory systems. Unknown is whether there is a global or sensory-specific mechanism that regulates the final perceptual outcome of this streaming process. To test the extent of modality independence in perceptual control, an auditory streaming experiment, and a visual moving-plaid experiment were performed. Both were designed to evoke alternating perception of an integrated or segregated percept. In both experiments, …