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University of Massachusetts Amherst

2010

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The Redshift Search Receiver 3 Mm Wavelength Spectra Of 10 Galaxies, Ronald L. Snell, Gopal Naraynan, Min S. Yun, Mark Heyer, Aeree Chung, William M. Irvine, Neal R. Erickson, Guilin Liu Dec 2010

The Redshift Search Receiver 3 Mm Wavelength Spectra Of 10 Galaxies, Ronald L. Snell, Gopal Naraynan, Min S. Yun, Mark Heyer, Aeree Chung, William M. Irvine, Neal R. Erickson, Guilin Liu

Neal Erickson

The 3 mm wavelength spectra of 10 galaxies have been obtained at the Five College Radio Astronomy Observatory using a new, very broadband receiver and spectrometer, called the Redshift Search Receiver (RSR). The RSR has an instantaneous bandwidth of 37 GHz covering frequencies from 74 to 111 GHz, and has a spectral resolution of 31 MHz (~100 km/s). During tests of the RSR on the FCRAO 14 m telescope the complete 3 mm spectra of the central regions of NGC 253, Maffei 2, NGC1068, IC 342, M82, NGC 3079, NGC 3690, NGC 4258, Arp 220 and NGC 6240 were obtained. …


Application Of Cyclic Voltammetry To Investigate Enhanced Catalytic Current Generation By Biofilm-Modified Anodes Of Geobacter Sulfurreducens Strain Dl1 Vs. Variant Strain Kn400, Sarah M. Strycharz, Anthony P. Malanoski, Rachel M. Snider, Hana Yi, Derek Lovley, Leonard M. Tender Dec 2010

Application Of Cyclic Voltammetry To Investigate Enhanced Catalytic Current Generation By Biofilm-Modified Anodes Of Geobacter Sulfurreducens Strain Dl1 Vs. Variant Strain Kn400, Sarah M. Strycharz, Anthony P. Malanoski, Rachel M. Snider, Hana Yi, Derek Lovley, Leonard M. Tender

Derek Lovley

A biofilm of Geobacter sulfurreducens will grow on an anode surface and catalyze the generation of an electrical current by oxidizing acetate and utilizing the anode as its metabolic terminal electron acceptor. Here we report qualitative analysis of cyclic voltammetry of anodes modified with biofilms of G. sulfurreducens strains DL1 and KN400 to predict possible rate-limiting steps in current generation. Strain KN400 generates approximately 2 to 8-fold greater current than strain DL1 depending upon the electrode material, enabling comparative electrochemical analysis to study the mechanism of current generation. This analysis is based on our recently reported electrochemical model for biofilm-catalyzed …


Discrete Breathers At The Interface Between A Diatomic And A Monoatomic Granular Chain, C. Hoogeboom, G. Theocharis, Panos Kevrekidis Dec 2010

Discrete Breathers At The Interface Between A Diatomic And A Monoatomic Granular Chain, C. Hoogeboom, G. Theocharis, Panos Kevrekidis

Panos Kevrekidis

In the present work, we develop a systematic examination of the existence, stability, and dynamical properties of a discrete breather at the interface between a diatomic and a monoatomic granular chain. We remarkably find that such an “interface breather” is more robust than its bulk diatomic counterpart throughout the gap of the linear spectrum. The latter linear spectral gap needs to exist for the breather state to arise and the relevant spectral conditions are discussed. We illustrate the minimal excitation conditions under which such an interface breather can be “nucleated” and analyze its apparently weak interaction with regular highly nonlinear …


The Effect Of Intellidrive On The Efficiency Of Highway Transportation Systems, Mohammad Nekoui, Hossein Pishro-Nik, Daiheng Ni Dec 2010

The Effect Of Intellidrive On The Efficiency Of Highway Transportation Systems, Mohammad Nekoui, Hossein Pishro-Nik, Daiheng Ni

Daiheng Ni

Recently, the IntelliDrive initiative has been proposed by the US Department of Transportation (USDOT) to enhance on-road safety and efficiency. In this study, we provide a mathematical framework which predicts the effect of such technologies on the efficiency of multilane highway systems prior to their real-life deployment. Our study shall encompass mixed traffic conditions in which a variety of assisted, automated and unequipped vehicles coexist. We show that intervehicular communications improves the flow of vehicles by reducing the perception-reaction (P-R) times of drivers and, in some cases, allowing for more efficient lane-changing operations. As we shall see, unlike the latter, …


Discovering Issue-Based Voting Groups Within The Us Senate, Rachel Shorey, Andrew Mccallum, Hanna Wallach Dec 2010

Discovering Issue-Based Voting Groups Within The Us Senate, Rachel Shorey, Andrew Mccallum, Hanna Wallach

Andrew McCallum

Members of the US Senate cast votes on a wide array of issues. Understanding a senator's position on an issue is important to constituents, sources of campaign funding, and groups seeking to persuade senators or build consensus. Classifying senators' positions often falls into the hands of interest groups. Many lobbyists and issue-based organizations give senators scores based on the number of times senators vote in accordance with the organization's ideals. Organization staff must choose which bills to consider and then investigate their content manually. To produce more objective and replicable rankings, political scientists have developed statistical models to group and …


The Effect Of Intellidrive On The Efficiency Of Highway Transportation Systems, Mohammad Nekoui, Hossein Pishro-Nik, Daiheng Ni Dec 2010

The Effect Of Intellidrive On The Efficiency Of Highway Transportation Systems, Mohammad Nekoui, Hossein Pishro-Nik, Daiheng Ni

Hossein Pishro-Nik

Recently, the IntelliDrive initiative has been proposed by the US Department of Transportation (USDOT) to enhance on-road safety and efficiency. In this study, we provide a mathematical framework which predicts the effect of such technologies on the efficiency of multilane highway systems prior to their real-life deployment. Our study shall encompass mixed traffic conditions in which a variety of assisted, automated and unequipped vehicles coexist. We show that intervehicular communications improves the flow of vehicles by reducing the perception-reaction (P-R) times of drivers and, in some cases, allowing for more efficient lane-changing operations. As we shall see, unlike the latter, …


Dose-Response, Vol 8, No 4, Table Of Contents Dec 2010

Dose-Response, Vol 8, No 4, Table Of Contents

Dose-Response: An International Journal

No abstract provided.


Dose-Response, Vol 8, No 4, Cover Dec 2010

Dose-Response, Vol 8, No 4, Cover

Dose-Response: An International Journal

No abstract provided.


Tnf-Α And Microglial Hormetic Involvement In Neurological Health & Migraine, Richard P Kraig, Heidi M Mitchell, Barbara Christie-Pope, Phillip E Kunkler, David M White, Ya-Ping Tang, George Langan Dec 2010

Tnf-Α And Microglial Hormetic Involvement In Neurological Health & Migraine, Richard P Kraig, Heidi M Mitchell, Barbara Christie-Pope, Phillip E Kunkler, David M White, Ya-Ping Tang, George Langan

Dose-Response: An International Journal

Environmental enrichment, i.e., increased intellectual, social, and physical activity makes brain more resilient to subsequent neurological disease. The mechanisms for this effect remain incompletely defined, but evidence shows tumor necrosis factor-alpha (TNF- α) is involved. TNF-α, at acutely high levels, possesses the intrinsic capacity to enhance injury associated with neurological disease. Conversely, the effect of TNF-α at low-levels is nutritive over time, consistent with physiological conditioning hormesis. Evidence shows that neural activity triggers low-level pro-inflammatory signaling involving TNF-α. This low-level TNF-α signaling alters gene expression, resulting in an enhanced resilience to disease. Brain-immune signaling may become maladaptive when increased activity …


Mean Cancer Mortality Rates In Low Versus High Elevation Counties In Texas, John Hart Dec 2010

Mean Cancer Mortality Rates In Low Versus High Elevation Counties In Texas, John Hart

Dose-Response: An International Journal

There is controversy as to whether low levels of radiation (i.e., < 5 rem) pose a health risk. This brief inquiry compares archived cancer mortality data in counties having relatively low (0-250 feet above sea level), medium (500-1000 feet above sea level), and high (3000+ feet above sea level) elevations also having corresponding greater natural back- ground levels of radiation respectively. Cancer mortality was found to be lowest in the high elevation counties (mean = 58.2) followed by low elevation counties (67.5) and then medium elevation counties (70.4). Statistically significant differences were found between low –high elevations (p = 0.003), and medium – high elevations (p = 0.010), but not between low and medium elevations (p = 0.5). More rigorous research, with an accounting of con- founding variables, is indicated.


Stochastic Threshold Microdose Model For Cell Killing By Insoluble Metallic Nanomaterial Particles, Bobby R Scott Dec 2010

Stochastic Threshold Microdose Model For Cell Killing By Insoluble Metallic Nanomaterial Particles, Bobby R Scott

Dose-Response: An International Journal

This paper introduces a novel microdosimetric model for metallic nanomaterial-parti- cles (MENAP)-induced cytotoxicity. The focus is on the engineered insoluble MENAP which represent a significant breakthrough in the design and development of new products for consumers, industry, and medicine. Increased production is rapidly occurring and may cause currently unrecognized health effects (e.g., nervous system dysfunction, heart disease, cancer); thus, dose-response models for MENAP-induced biological effects are needed to facilitate health risk assessment. The stochastic threshold microdose (STM) model presented introduces novel stochastic microdose metrics for use in constructing dose- response relationships for the frequency of specific cellular (e.g., cell killing, …


Dose-Dependency Of Resveratrol In Providing Health Benefits, Subhendu Mukherjee, Jocelyn I Dudley, Dipak K Das Dec 2010

Dose-Dependency Of Resveratrol In Providing Health Benefits, Subhendu Mukherjee, Jocelyn I Dudley, Dipak K Das

Dose-Response: An International Journal

This review describes the dose-dependent health benefits of resveratrol, a polyphenolic antioxidant that is found in a variety of foods, especially grape skin and red wine. Resveratrol provides diverse health benefits including cardioprotection, inhibition of low- density lipoprotein, activation of nitric oxide (NO) production, hindering of platelet aggregation [32] A.A.E. Bertelli, D.E. Giovannini, R.L. Caterina, W. Bernini, M. Migliori and M. Fregoni et al., Antiplatelet activity of cis-resveratrol, Drugs Exp Clin Res 22 (1996), pp. 61–63. View Record in Scopus | Cited By in Scopus (111) and promotion of anti-inflammatory effects. Studies have shown that at a lower dose, resveratrol …


Exposure To Nanoparticles And Hormesis, Ivo Iavicoli, Edward J Calabrese, Marc A Nascarella Dec 2010

Exposure To Nanoparticles And Hormesis, Ivo Iavicoli, Edward J Calabrese, Marc A Nascarella

Dose-Response: An International Journal

Nanoparticles are particles with lengths that range from 1 to 100 nm. They are increasingly being manufactured and used for commercial purpose because of their novel and unique physicochemical properties. Although nanotechnology-based products are gener- ally thought to be at a pre-competitive stage, an increasing number of products and mate- rials are becoming commercially available. Human exposure to nanoparticles is therefore inevitable as they become more widely used and, as a result, nanotoxicology research is now gaining attention. However, there are many uncertainties as to whether the unique properties of nanoparticles also pose occupational health risks. These uncertainties arise because …


Phytotoxic Antibiotic Sulfadimethoxine Elicits A Complex Hormetic Response In The Weed Lythrum Salicaria L., Luciana Migliore, Alice Rotini, Nadia L Cerioli, Salvatore Cozzolino, Maurizio Fiori Dec 2010

Phytotoxic Antibiotic Sulfadimethoxine Elicits A Complex Hormetic Response In The Weed Lythrum Salicaria L., Luciana Migliore, Alice Rotini, Nadia L Cerioli, Salvatore Cozzolino, Maurizio Fiori

Dose-Response: An International Journal

In order to evaluate the hormetic response of the weed Lythrum salicaria to drug expo- sure we investigated the effects of the antibiotic Sulfadimethoxine by growing Lythrum plants for 28 days on culture media containing different drug concentrations (between 0.005 and 50 mg.L-1). The antibiotic was absorbed by plants and can be found in plant tissue. The plant response was organ-dependent: roots, cotyledons and cotyledon petioles, were always affected by a toxic effect, whilst internodes and leaves length, showed a variable dose-depending response, with an increased growth at the lower drug concentrations and toxic effects at the higher …


Hormetic Electric Field Theory Of Pattern Formation, Egil Fosslien Dec 2010

Hormetic Electric Field Theory Of Pattern Formation, Egil Fosslien

Dose-Response: An International Journal

The hormetic morphogen theory of curvature (Fosslien 2009) proposes that hormetic morphogen concentration gradients modulate the synthesis of adenosine triphosphate (ATP) by cells along the gradients (field cells) and thus regulate their proliferation and induce curvature such as vascular wall curvature; however, it is unclear whether such morphogen gradients can also determine the histological pattern of the walls. Here, I propose that the ATP gradients modulate export of H+ by vacuolar H+-ATPase (V-ATPase) located on the surface of field cells and generate extracellular ion concentration gradients, ion currents and electrical fields along the paths of morphogen gradients. …


Low-Dose Pretreatment For Radiation Therapy, Richard Blankenbecler Dec 2010

Low-Dose Pretreatment For Radiation Therapy, Richard Blankenbecler

Dose-Response: An International Journal

In radiotherapy, a large radiation dose must be applied to both cancer and neighboring healthy cells. Recent experiments have shown that a low dose of ionizing radiation turns on certain protective mechanisms that allow a cell to better survive a subsequent high dose of radiation. This adaptive response can have important and positive consequences for radiotherapy. This paper describes a simple change in treatment procedures to make use of these beneficial effects. A low dose applied only to the healthy cells will probably produce some damage. However, it will also start the adaptive response which will yield increased protection when …


Effects Of Ethanol On The Shoaling Behavior Of Zebrafish (Danio Rerio), Anastasia Kurta, Brian G. Palestis Dec 2010

Effects Of Ethanol On The Shoaling Behavior Of Zebrafish (Danio Rerio), Anastasia Kurta, Brian G. Palestis

Dose-Response: An International Journal

Ethanol (EtOH) often has stimulatory effects at low doses and inhibitory effects at high doses, affecting behavior and physiology of many organisms in a non-linear manner suggestive of hormesis. Zebrafish (Danio rerio) shoaling was studied in adult fish exposed to one of five different EtOH concentrations (v/v): 0.0% control, 0.125%, 0.25%, 0.5%, and 1.0%. Digital photographs of groups of four fish were taken every 2 min, with each trial lasting a total of 12 min. The median nearest neighbor distance and shoal area were calculated for each photograph. Exposure to 1.0% EtOH inhibited shoaling. In contrast, as predicted …


Modeling Dose-Response At Low Dose: A Systems Biology Approach For Ionization Radiation, Yuchao Zhao, Paolo F Ricci Dec 2010

Modeling Dose-Response At Low Dose: A Systems Biology Approach For Ionization Radiation, Yuchao Zhao, Paolo F Ricci

Dose-Response: An International Journal

For ionization radiation (IR) induced cancer, a linear non-threshold (LNT) model at very low doses is the default used by a number of national and international organizations and in regulatory law. This default denies any positive benefit from any level of exposure. However, experimental observations and theoretical biology have found that both linear and J-shaped IR dose-response curves can exist at those very low doses. We develop low dose J-shaped dose-response, based on systems biology, and thus justify its use regarding expo- sure to IR. This approach incorporates detailed, molecular and cellular descriptions of biological/toxicological mechanisms to develop a dose-response …


Fairmount Greenway - A Community Initative, Leah H. Bamberger, Liliana Carvajal, Mary F. Dehais, Yuanfang Gong, John E. Hulsey, Eric C. Kells, Kimberley Klosterman, Pamela Jo Landi, Adam G. Monroy, Seth A. Morrow, Bryan O'Bara, Jie Su, Arianna Thompson, Owen M. White Dec 2010

Fairmount Greenway - A Community Initative, Leah H. Bamberger, Liliana Carvajal, Mary F. Dehais, Yuanfang Gong, John E. Hulsey, Eric C. Kells, Kimberley Klosterman, Pamela Jo Landi, Adam G. Monroy, Seth A. Morrow, Bryan O'Bara, Jie Su, Arianna Thompson, Owen M. White

Landscape Architecture & Regional Planning Studio and Student Research and Creative Activity

This studio was based on the Fairmount Greenway that was developed through a series of public meetings with the neighborhood community and with consultants from the firm Crosby, Schlessinger and Smallridge (CSS). The Fairmount Greenway, while drawing its identity from the traditional greenway model is in fact a reinterpretation of an urban greenway. The greenway path follows along both primary and secondary city streets because of the lack of space along the rail right-of-way. The Fairmount Greenway begins at what will be a new station stop at New Market South Bay near Upham’s Corner in northern Dorchester. The greenway follows …


A Community Of Households: Early 19th-Century Enslaved Landscapes At James Madison's Montpelier, Matthew Reeves Dec 2010

A Community Of Households: Early 19th-Century Enslaved Landscapes At James Madison's Montpelier, Matthew Reeves

African Diaspora Archaeology Newsletter

No abstract provided.


Archaeological Investigations And Lidar Aerial Survey In Edgefield, South Carolina, Christopher Fennell Dec 2010

Archaeological Investigations And Lidar Aerial Survey In Edgefield, South Carolina, Christopher Fennell

African Diaspora Archaeology Newsletter

No abstract provided.


The Old Plantation Painting At Colonial Williamsburg: New Findings And Some Observations, Jerome S. Handler Dec 2010

The Old Plantation Painting At Colonial Williamsburg: New Findings And Some Observations, Jerome S. Handler

African Diaspora Archaeology Newsletter

No abstract provided.


Okra Soup And Earthenware Pots: The Archaeology Of Gullah Communities, Carl Steen, Jodi A. Barnes Dec 2010

Okra Soup And Earthenware Pots: The Archaeology Of Gullah Communities, Carl Steen, Jodi A. Barnes

African Diaspora Archaeology Newsletter

No abstract provided.


Christopher Barton Joins As Adan Newsletter Co-Editor Dec 2010

Christopher Barton Joins As Adan Newsletter Co-Editor

African Diaspora Archaeology Newsletter

No abstract provided.


Cultural Heritage Resources Of The New Oyo Empire, Southwestern Nigeria: Prospects For Sustainability, Titilayo O. Olukole Dec 2010

Cultural Heritage Resources Of The New Oyo Empire, Southwestern Nigeria: Prospects For Sustainability, Titilayo O. Olukole

African Diaspora Archaeology Newsletter

No abstract provided.


Dr. Cheryl Laroche Receives 2011 John L. Cotter Award By Society For Historical Archaeology Dec 2010

Dr. Cheryl Laroche Receives 2011 John L. Cotter Award By Society For Historical Archaeology

African Diaspora Archaeology Newsletter

No abstract provided.


Crossroads And Cosmologies Receives 2010 Gustave O. Arlt Award In The Humanities By Council Of Graduate Schools Dec 2010

Crossroads And Cosmologies Receives 2010 Gustave O. Arlt Award In The Humanities By Council Of Graduate Schools

African Diaspora Archaeology Newsletter

No abstract provided.


Judith Carney, Siddharth Kara, And Richard Rosomoff Share Frederick Douglass Book Prize Dec 2010

Judith Carney, Siddharth Kara, And Richard Rosomoff Share Frederick Douglass Book Prize

African Diaspora Archaeology Newsletter

No abstract provided.


African And Africanist Archaeologists Voice Their Support Of Anthropology At Howard University, Flordeliz T. Bugarin Dec 2010

African And Africanist Archaeologists Voice Their Support Of Anthropology At Howard University, Flordeliz T. Bugarin

African Diaspora Archaeology Newsletter

No abstract provided.


Racism Plagues Every Society -- Un Reports Dec 2010

Racism Plagues Every Society -- Un Reports

African Diaspora Archaeology Newsletter

No abstract provided.