Digital Commons Network^™

S100b As A Protein Marker For Intracranial Hemorrhages, Anthony Phan

Student Research Symposium

This study aims to evaluate the effectiveness of S100B as a protein marker for patients that are clinically diagnosed with an Intracranial Hemorrhage (ICH). This study enrolled patients that present to the hospital as a trauma activation consistent with a traumatic brain injury (either a blunt or penetrating traumatic mechanism) who are 15 or older, GCS of 12 or lower, and received the placebo arm of the TXA drug. The S100B level of patients will be measured through an Enzyme-Linked Immunosorbent Assay (ELISA). After the data collection, a statistical test will be conducted to determine the level of significance for …

Selection During Reproduction In Mimulus Guttatus, Desmond C. Willson, Karla De Lima Berg, Mitch Cruzan

Student Research Symposium

A lack of genomic studies examining gametophytic selection and selective embryo abortion—which occur during the reproduction of angiosperms—leaves questions regarding the adaptive and evolutionary effects of these processes. Analyzing deviations from Mendelian segregation offers an avenue for identifying loci targeted by GS and SEA, and their contributions to purging of genetic load. However, other selective processes such as meiotic drive and cytonuclear interactions, as well as pollen and ovule abortion, can cause distortion. To distinguish the effects of GS and SEA from other causes of distortion, we will perform reciprocal crosses between highly homozygous and highly heterozygous individuals of Mimulus …

Mutagenetic Analysis Of The Minor Capsid Protein Vp3 Of The Archaeal Fusellovirus Ssv1, Laura Costal Lagarde

Student Research Symposium

Viruses, while often associated with disease, are integral to life and play an important role in the microbiome. Despite their importance in medical research, archaeal viruses, particularly those found in extreme environments, are not widely understood. The Sulfolobus Spindle-Shaped Viruses (SSVs) of the Fuselloviridae family are unique among viruses in that they do not kill their host, the archaeon Sulfolobus Solfataricus in volcanic hot springs, but rather slow its growth, allowing for halo assay assessments.The study focuses on the type virus SSV1, which is predominantly composed of the Major and Minor capsid proteins vp1 and vp3, respectively. Previous study has …

Self-Balancing Robot Leg, Ben Bolen

Student Research Symposium

Research in the Agile and Adaptive Robotics Lab involves the creation of biomimetic robots. To this end, we developed a self-balancing robot leg actuated with braided pneumatic actuators (BPAs)—a type of pneumatic artificial muscle. These BPAs, akin to human muscles, exhibit properties such as high strength-to-weight ratio and tunable passive stiffness. An Inertial Measurement Unit (IMU) was placed on top of the tibia for feedback and the tibia and foot were connected with a hinge joint. The orientation of the ankle joint was controlled with an Arduino microcontroller sending commands to the proportional pressure valves supplying the BPAs. Leg balance …

Exploring Speech Experiences, Cpib Scores, And Aac Assessment Experiences Of Autistic Aac Users With Intermittent, Unreliable, Insufficient, And/Or Expensive Speech, Karina Rayl, Pang Lee Herr, Brandon Eddy, Amy Donaldson, Stephanie Fuller, Alyssa Zisk

Student Research Symposium

There is growing evidence from the perspectives of speaking autistic people that augmentative and alternative communication (AAC) supports their self-expression and communicative agency. Despite the evidence supporting the communication effectiveness of AAC, autistic adults have reported that professionals often prioritized speech as the ideal communicative method rather than offering AAC as a communication option. This study will investigate autistic adults’ AAC assessment experiences and explore whether a modified version of the Communication Participation Item Bank (CPIB) self-rating questionnaire could be an effective tool to document the internal states of intermittent, unreliable, insufficient, and/or expensive speech. Surveys will be distributed to …

Multiscale Variability Of Heavy Metals In A Western U.S. Snowpack, Kelsey Hefner

Student Research Symposium

Natural and anthropogenically sourced particulates are deposited from the atmosphere to landscapes via dry and wet deposition, making frozen winter snowpack a natural archive of atmospheric elemental composition. Wildfires in the Western United States are increasing in extent, duration, and severity, especially in alpine regions. Severe fires remove forest canopy and can impact how atmospheric elements are dispersed and stored across snow-dominated watersheds. We evaluated Al, V, Cr, Mn, Ni, Cu, As, Zn, Se, Mo, Cd, and Pb concentrations in 394 winter snow core samples. We collected samples in 2019 and 2020 from a chronosequence of eight forests that burned …

Neutron Time Of Flight Spectrometry As A Diagnostic Tool For Inertial Electrostatic Confinement Fusion Plasmas, Andrew H. Dempsey, Erik J. Sanchez

Student Research Symposium

Inertial electrostatic confinement (IEC) is a method for achieving fusion of light nuclei wherein ions are injected into a spherically symmetric system of concentric electrodes. When the innermost electrode is held at negative high voltage with respect to the outer electrode, ions injected into the reactor at cathode (ground) potential accelerate toward the anode where they may undergo collisions with sufficient energy to overcome Coulomb repulsion and achieve nuclear fusion. The most commonly used IEC fusion fuels are deuterium-deuterium (D-D) and deuterium-tritium (D-T). Both fuels undergo fusion reactions that result in production of fast neutrons with distinct energies. Neutron production …

Examining The Role Of Rgs2 In The Maintenance Of Diapause After Anoxic Stress In Embryos Of The Annual Killifish Austrofundulus Limnaeus, Patrick Clouser

Student Research Symposium

Austrofundulus limnaeus live in ephemeral ponds of Venezuela. They have evolved a unique life history that includes embryonic diapause, a period of developmental dormancy, metabolic arrest, and reduced protein synthesis. Diapausing embryos are resistant to environmental stress and survive months without oxygen (anoxia). A. limnaeus’ anoxia tolerance is an important survival mechanism as they can be buried in anoxic soil during development. Analysis of RNAseq data from diapausing A. limnaeus embryos show significant down-regulation of RGS2 transcripts in anoxic embryos. RGS2 regulates G-protein receptor signaling by inhibiting associated G_a-proteins and can inhibit protein synthesis. I hypothesis that …

Locating Vitamin D Receptors (Vdrs) In Annual Killifish, Austrofundulus Limnaeus, Rosalia N. Tanori, Amie L. Romney, Jason E. Podrabsky

Student Research Symposium

Austrofundulus limnaeus, a species of annual killifish found in unpredictable temporary habitats in South America, has a profound ability to survive long periods without water and oxygen. This tolerance is associated with the ability to enter metabolic dormancy associated with diapause. Entrance into diapause and tolerance of environmental stress is governed by an interplay of genetic and environmental factors. The vitamin D receptor (VDR) is among these factors and plays a crucial role in determining if an embryo will enter diapause or actively develop. My work aims to identify the genomic locations of VDR proteins in the A. limnaeus genome …

Second Language Impacts On First Language Processing, Natalie Robison, Sarah C. Creel, Sarah Elkington, Judith Kelholt, Amy Lin, Carolyn Quam

Student Research Symposium

This line of research investigates attrition (loss of fluency) of native Mandarin language (L1) proficiency with increasing proficiency in English. English uses pitch to denote intonation (e.g., “it’s there?” versus “it’s there!”), while Mandarin uses pitch to indicate word meanings; e.g., /he/ means “drink” with a high, level tone, or “river” with a rising tone. The present study delineates between two alternative explanations for the prior finding (Quam & Creel, 2017) that English proficiency correlates with attrition of Mandarin tones, but not vowels. This pattern could be explained by 1) language assimilability (L1-L2 Assimilability Hypothesis), or 2) by tone being …

Describing Shen & Shen Ming Via A Hybrid Quantum Computational Model, Alex M. Cullen, Johnny Lemau

Student Research Symposium

Definitions for Traditional Chinese Medicine (TCM) terminology within the context of quantum biology (QB) have recently been proposed. These definitions aim to elucidate concepts such as qi meridians in TCM. Our study presents a hypothesis that seeks to provide an operational definition for Spirit (Shen) and Bright Spirit (Shen Ming) in TCM via a scoping review. We propose that Shen represents physical, phenomenological proto-consciousness/consciousness in the forms of computation, such as singular particles/bits/qubits, computers, organisms, or computational strategies, whereas Shen Ming may refer to emergent, quasi-physical meta-proto-consciousness/consciousness formed by coherent relationships of multiple orchestrated/integrated units of computation; manifesting itself as …

Neuroscience Educational Interventions For Mental Health Management Within The Neurodiverse Population: A Working Model, Kadi Rae Smith, C.K. Miller, Bill Griesar, Jeff Leake

Student Research Symposium

Sociological and environmental factors such as economic disparity and cultural marginalization hinder access to educational and medical resources and must be taken into account to ensure accurate diagnoses, effective self-regulation and mental health management for neurodiverse individuals, and offset disparities in access to healthcare and education. Arbitrary attachment of stigma to traits commonly associated with neurodivergence perpetuate neuro-myths1 that have dire consequences when internalized, informing individuals’ development and sense of self. Neuroscience outreach done by NW Noggin is an active model for engaging communities with limited resources and a greater need for services to offset economic disparity. Integrated arts programming …

Impact Of Mindfulness-Oriented Recovery Enhancement On Pain And Disability In Patients With Chronic Lumbosacral Radiculopathy: Results From An Rct, Danielle Zuzero

Student Research Symposium

Lumbosacral Radiculopathy (LR), also known as sciatica, is a common type of radiating neurologic pain in the lower extremities with an estimated lifetime prevalence as high as 43%. The goal of this randomized control trial was to determine the impact of virtually delivered Mindfulness-Oriented Recovery Enhancement (MORE) on patients with LR. Participants were randomized to MORE sessions or treatment-as-usual (TAU) for 8 consecutive weeks, pain intensity was collected daily via email. At baseline and follow-up visits, participants completed questionnaires of disability, quality of life, depression, mindful interpretation of pain, and train mindfulness. Patients undergoing MORE sessions had greater improvement in …

Differences In Ninth Graders’ Attitudes Towards Math Depending On Immigrant-Generation Status, Karla V. Santana Martinez, Dara Shifrer

Student Research Symposium

Introduction

Math is a subject that is often perceived as challenging and sometimes referred to as a universal language because the symbols and organization are the same from country to country. However, immigrant students can face obstacles such as language barriers that can make math even more challenging regardless of the universal language belief.

Methods

This research integrates the data from the High School Longitudinal Study of 2009 on 20,000 ninth graders. The ninth graders were asked questions about math and their feelings on the subject.

Results

Among students with the highest scores on the standardized math test, the math …

Guide Rna Design And Delivery For Crispr/Cas9 Editing In Annual Killifish, Keria N. Moritsugu-Vandehey, Isabel Henkes, Yekaterina Chmykh, Amie Romney, Jason Podrabsky

Student Research Symposium

The CRISPR-Cas9 genome editing tool has shown to be successful in knocking out genes in model organisms such as zebrafish, turquoise killifish, and cichlid fish. CRISPR-Cas9 genome editing has been demonstrated in many species of fish, but this technology has not been verified in the annual killifish, Austrofundulus limnaeus. We hypothesize that targeted editing of the tyrosinase gene in embryos of A. limnaeus would lead to the development of fish without the ability to produce melanin, the black/brown pigment molecule. Early embryos (1-cell stage) were injected with a Cas9 cocktail containing a mix of guide RNA molecules that target …

Impact Of Testosterone Therapy On Voices In Trans-Masculine People: A Scoping Review, Samuel E. Hedine, Jeff Conn, Deanna Britton

Student Research Symposium

Treatment of trans people by speech-language pathologists (SLPs) dates back to at least the 1980s. However, the majority of early research on the voices of trans people focused on trans-women. More recently, the field of speech-language pathology has garnered more interest in the effects of testosterone therapy in trans-masculine individuals. The goal of this project is to review current research, and compile the known effects of testosterone therapy in the trans-masculine population on common acoustic indices of voice production, including fundamental frequency (pitch), decibels/sound pressure level (dB SPL; loudness) and cepstral peak prominence (voice quality). A scoping literature search was …

Qibc Analysis On Killifish Cells Under Anoxic Conditions, Jaina Canlas

Student Research Symposium

Faithful DNA replication is vital for all living organisms. Environmental stressors can cause a multitude of mutations and DNA lesions during replication leading to cell death if not accurately repaired. The annual killifish, Austrofundulus limnaeus, has a heightened tolerance to many known genotoxic stressors, including anoxia. Embryos of the annual killifish can survive months of anoxia during the dry season when the ephemeral ponds they inhabit, completely dry. During these exposures, they have shown they are capable of repairing substantial amounts of damaged DNA. This resilience has led us to hypothesize that A. limnaeus have enhanced DNA repair capabilities. …

Reducing Switching Noise And Losses In Two-Stage Electric Power Converters, Abhijeet Prem

Student Research Symposium

Advancements in semiconductor devices are enabling the design of better electrical power converter systems. Wide Bandgap (WBG) switching devices from Silicon Carbide and Gallium Nitride can operate at high temperatures, voltages, and frequencies with faster turn-on/off periods, improving converter performance over silicon devices. However, WBG technology is still new, and the rapid switching transitions of these devices lead to issues such as voltage overshoots, ringing, and electromagnetic interference, which need to be addressed for widespread adoption. This work introduces a new control method for reshaping the switching voltages, which overcomes the disadvantages of fast transition time without increasing the system's …

Wildland Urban Interface Growth And Development Potentials In Deschutes County, Samantha Hall

Student Research Symposium

Policy can and has been used as a tool to reduce the risk communities experience from natural hazards by limiting development in areas most vulnerable. How and where development occurs directly influences the amount of risk a community experiences from natural hazards like hurricanes, earthquakes, flash floods, and wildfire among others. Development patterns that contribute to increased wildfire risk mostly occur within the wildland urban interface, a land use type where development is at the fringes or intercept of wildland areas and is more flammable due to surrounding vegetation, slope, local climate, and other factors. For this research, Deschutes County …

Construction And Mutagenesis Of Ssv1 Mutants In Extreme Viruses, Lou Ann F. O'Connor, Jono Abshier, Kenneth M. Stedman

Student Research Symposium

Archaeal viruses with unique structures such as spindle-shaped virions are found abundantly in extreme environments like geothermal hot springs around the world. Among all spindle-shaped viruses, the model Sulfolobus Spindle-shaped Virus 1 (SSV1) is best studied. Creating the lemon-shaped or spindle-shaped virion structure are two proteins, VP1 as the major capsid protein, and VP3 as the minor capsid protein. The primary structure of VP1 consists of a proteolytic cleavage site at position 66 that is believed to be necessary for virus evolution. Recent studies showed that genetic mutation of the amino acid, glutamate (E) at position 66 in VP1 which …

Recovery Of Black Carbon Concentrations In Burned Forests, Monica V. Zapata Villegas, Kelly E. Gleason

Student Research Symposium

Forest fires shed light absorbing particles (LAP), such as black carbon and burned woody debris, into snowpacks, darkening snow surface albedo, and advancing snowmelt timing and snow disappearance patterns for decades following fire. Although the role of LAPs in seasonal snow has been extensively studied in recent years, the spatiotemporal variability of LAPs and contributions to snowmelt relative to years since fire and burn severity is still unknown. In the Triple Divide region of western Wyoming, the headwaters of the Colorado, Columbia, and Missouri rivers, we quantified the spatiotemporal variability of forest fire effects on snow albedo, using geochemical analysis …

The Longitudinal Relationship Between Socioeconomic Status, Child Separation Anxiety Symptoms, And School Achievement In 1st Grade, Filip-Bogdan Serban-Dragan

Student Research Symposium

This informative poster highlights a study examining the association between child separation anxiety disorder (SAD) and school achievement, considering socioeconomic status (SES) and perceived financial stress. Data came from the Early Growth and Development Study (EGDS). Data from the kindergarten (age 6) and 1^st grade (age 7) assessments in the adoptive families (N=360 adoptive triads) were analyzed.

By controlling for parent’s income, financial stress, child’s gender and by measuring children at two time points (6 and 7 years), our study aims to identify the specific contribution of separation anxiety on academic achievement, enhancing our understanding of this …

Cultivating Connections: Future Approaches To Tourism Esl Pedagogy, Kelly Abrams

Student Research Symposium

My poster will display my research that investigates the pivotal role of English for Specific Purposes (ESP) in Cuba's tourism sector and its broader implications for global tourism contexts. Through qualitative methods including written questionnaires and oral interviews with people working in the tourism industry in Cuba, I examined the significance of language proficiency, particularly English, in various industry roles within Cuba's tourism and hospitality sector. Findings highlight how ESP facilitates effective communication, elevates service standards, and fosters career progression for individuals working in the sector. Furthermore, my research underscores the interconnectedness of language and tourism, emphasizing the importance of …

Why People Pee In Public: Is A Lack Of Public Restrooms Keeping Portland Too Weird?, Cece Austin

Student Research Symposium

Various factors, including gender, housing status, socioeconomic status, and disability, impact access to public restrooms in Portland, Oregon. A pilot program involving the implementation of public restrooms has caused a significant reduction in public defecation in San Francisco. This research demonstrates the efficacy of this existing working model, which could be similarly implemented in Portland with some adjustments. Portland has the Portland Loos, which are single-stall, outdoor public restrooms. Still, many are not open 24 hours. An analysis of publicly available Google reviews indicates consistent poor cleanliness and Portland Loos being locked at times when they are advertised to be …

Talking About Weight: Weight Stigma And Information Seeking, Alexandra N. Henrici, Lillian H. Mantel

Student Research Symposium

Guided by the Risk Information Seeking and Processing (RISP) model, this study explores the relationship between fear of discussing weight-related topics, or weight-related communication apprehension and weight bias internalization and tests the inconsistent RISP relationship between risk perception and information insufficiency. It investigates differences in weight-related communication apprehension in those who previously sought weight-related information from interpersonal or mediated sources. Using a survey of 64 undergraduate communication students, the study found that high levels of weight bias internalization correlated with high levels of weight-related communication apprehension. The study did not find a significant difference in weight-related communication apprehension based on …

Development Of A Two-Photon Laser Scanning Microscope, Jess Hollenbaugh

Student Research Symposium

The objective of this project was to convert a Sarastro 2000 confocal laser scanning microscope into a system capable of imaging using two-photon excitation (TPE) fluorescence for the use of the PSU biology department. TPE microscopy operates on the ability of fluorophores to accept two photons each with half the energy of a desired transition in a single quantum event via a virtual energy state and then emit a higher energy photon upon relaxation. This is preferable to single-photon excitation (SPE) due to the lower energy photons causing less damage to delicate biological samples. The adaptation process included physically altering …

Annual Killifish: Eye Development And Retinal Cell Regeneration, Carmen Z. Rodriguez

Student Research Symposium

Vertebrate eye development is highly conserved. Current models have allowed the understanding of gene expression patterns that support eye development, but lack the context of extreme environmental conditions that challenge these fundamental programs. Typical vertebrate life spans can be years, but annual killifish, Austrofundulus limnaeus, are able to complete their entire adult lifespan in only weeks. Thus, A. limnaeus is a strong model for age-related macular degeneration. A. limnaeus also experiences embryonic diapause; a period of developmental dormancy. Developing/diapausing embryos of A. limnaeus are resistant to environmental stresses such as hypoxia/anoxia that would cause irreparable damage to vital organs, such …

Histone Changes As A Response To Lactic Acid Selection In Cells Of Austrofundulus Limnaeus, Lori Tran, Jason Podrabsky, Chelsea Hughes

Student Research Symposium

The killifish Austrofundulus limnaeus is an extremophile native to small temporary ponds of Venezuela. Normal embryonic development of A. limnaeus is segmented into up to three stages of metabolic depression (diapause), and both developing and diapausing embryos can survive long bouts of the complete absence of oxygen (anoxia) by using anaerobic metabolic pathways. While there has been much focus on how mutations in DNA drive evolution, environmental stress can cause heritable changes to histone post-translational modifications (hPTMs) in multiple species. However, this evolutionary role of hPTMs has never been studied in A. limnaeus. Additionally, the possible evolutionary role of extracellular …

Promoting Student Engagement In Research In An Undergraduate Language-Development Course, Mitchell Kloer, Isabelle Trujillo, Teresa Roberts, Carolyn Quam

Student Research Symposium

This presentation will provide student perspectives on benefits of incorporating inclusive research activities within an undergraduate Speech and Hearing Sciences course. In Speech and Language Development in Children (SPHR 372U), instructor Quam incorporates a research project focusing on an issue of equity, inclusion, and social justice. One overarching goal is to reduce barriers of access to scientific research and increase engagement for college students, particularly those from historically underrepresented groups. The project is segmented into 3 steps that mirror literature review, critical analysis, and proposal. The project is collaborative, iterative throughout the term, and each step in the research process …

Stem Students And Faculty See Value In A Classroom Belonging Exercise, Kaisa S. Holt, Elizabeth A. Runkel-Baez

Student Research Symposium

Enhancing belonging in undergraduate STEM classrooms are pivotal for student success. This study examines a belonging exercise's implementation and impact in multiple STEM courses from 2017 to 2019. Faculty perspectives were gathered from a survey of 92 respondents, indicating a high level of perceived benefit (92%). Coded responses highlighted shared experiences and diversity mindset promotion. 30% explicitly mentioned benefits for both students and instructors. Additionally, 76% of faculty saw potential of belonging exercises in their own classrooms. It is important to promote using belonging interventions and also understand how STEM students perceive their value and utility. Three focus groups with …