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Defining The Value Of Injection Current And Effective Electrical Contact Area For Egain-Based Molecular Tunneling Junctions, Felice C. Simeone, Hyo Jae Yoon, Martin M. Thuo, Jabulani R. Barber, Barbara Smith, George M. Whitesides Nov 2013

Defining The Value Of Injection Current And Effective Electrical Contact Area For Egain-Based Molecular Tunneling Junctions, Felice C. Simeone, Hyo Jae Yoon, Martin M. Thuo, Jabulani R. Barber, Barbara Smith, George M. Whitesides

Martin M. Thuo

Analysis of rates of tunneling across self-assembled monolayers (SAMs) of n-alkanethiolates SCn (with n = number of carbon atoms) incorporated in junctions having structure AgTS-SAM//Ga2O3/EGaIn leads to a value for the injection tunnel current density J0 (i.e., the current flowing through an ideal junction with n = 0) of 103.6±0.3 A·cm–2 (V = +0.5 V). This estimation of J0 does not involve an extrapolation in length, because it was possible to measure current densities across SAMs over the range of lengths n = 1–18. This value of J0 is estimated under the assumption that values of the geometrical contact area …

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Transgenic Mosquitoes Expressing A Phospholipase A(2) Gene Have A Fitness Advantage When Fed Plasmodium Falciparum-Infected Blood, Ryan C. Smith, Christopher Kizito, Jason L. Rasgon, Marcelo Jacobs-Lorena Oct 2013

Transgenic Mosquitoes Expressing A Phospholipase A(2) Gene Have A Fitness Advantage When Fed Plasmodium Falciparum-Infected Blood, Ryan C. Smith, Christopher Kizito, Jason L. Rasgon, Marcelo Jacobs-Lorena

Ryan C. Smith

Genetically modified mosquitoes have been proposed as an alternative strategy to reduce the heavy burden of malaria. In recent years, several proof-of-principle experiments have been performed that validate the idea that mosquitoes can be genetically modified to become refractory to malaria parasite development. We have created two transgenic lines of Anophelesstephensi, a natural vector of Plasmodium falciparum, which constitutively secrete a catalytically inactive phospholipase A2 (mPLA2) into the midgut lumen to interfere with Plasmodium ookinete invasion. Our experiments show that both transgenic lines expressing mPLA2 significantly impair the development of rodent malaria parasites, but only one line impairs the development …

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A Microfluidic Paper-Based Electrochemical Biosensor Array For Multiplexed Detection Of Metabolic Biomarkers, Chen Zhao, Martin M. Thuo, Xinyu Liu Oct 2013

A Microfluidic Paper-Based Electrochemical Biosensor Array For Multiplexed Detection Of Metabolic Biomarkers, Chen Zhao, Martin M. Thuo, Xinyu Liu

Martin M. Thuo

Paper-based microfluidic devices have emerged as simple yet powerful platforms for performing low-cost analytical tests. This paper reports a microfluidic paper-based electrochemical biosensor array for multiplexed detection of physiologically relevant metabolic biomarkers. Different from existing paper-based electrochemical devices, our device includes an array of eight electrochemical sensors and utilizes a handheld custom-made electrochemical reader (potentiostat) for signal readout. The biosensor array can detect several analytes in a sample solution and produce multiple measurements for each analyte from a single run. Using the device, we demonstrate simultaneous detection of glucose, lactate and uric acid in urine, with analytical performance comparable to …

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Detection Of Boronic Acids Through Excited-State Intramolecular Proton-Transfer Fluorescence, Matthew R. Aronoff, Brett Vanveller, Ronald T. Raines Oct 2013

Detection Of Boronic Acids Through Excited-State Intramolecular Proton-Transfer Fluorescence, Matthew R. Aronoff, Brett Vanveller, Ronald T. Raines

Brett VanVeller

Boronic acids are versatile reagents for the chemical synthesis of organic molecules. They and other boron-containing compounds can be detected readily by the interruption of the excited-state intramolecular proton transfer (ESIPT) of 10-hydroxybenzo[h]quinolone. This method is highly sensitive and selective, and useful for monitoring synthetic reactions and detecting boron-containing compounds on a solid support.

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Project Complexity Mapping In Five Dimensions For Complex Transportation Projects, Douglas D. Gransberg, Jennifer S. Shane, Carla Lopez Del Puerto Oct 2013

Project Complexity Mapping In Five Dimensions For Complex Transportation Projects, Douglas D. Gransberg, Jennifer S. Shane, Carla Lopez Del Puerto

Douglas D. Gransberg

Traditional three-dimensional project management theory is based on optimizing the cost-schedule-technical dimensions. Recent studies in the United Kingdom, Canada, and Australia have shown that the current project management body of knowledge may not be adequate to address interrelated and dependent variables encountered on complex projects. This paper reports the findings of an international research team’s detailed study of eighteen complex projects, which confirms the findings of the previous research and proposes a framework upon which a complex transportation project’s scope of work can be better conceptualized and a methodology to graphically display a project’s complexity in order to better understand …

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Joint User Grouping And Linear Virtual Beamforming: Complexity, Algorithms And Approximation Bounds, Mingyi Hong, Zi Xu, Meisam Razaviyayn, Zhi-Quan Luo Oct 2013

Joint User Grouping And Linear Virtual Beamforming: Complexity, Algorithms And Approximation Bounds, Mingyi Hong, Zi Xu, Meisam Razaviyayn, Zhi-Quan Luo

Mingyi Hong

In a wireless system with a large number of distributed nodes, the quality of communication can be greatly improved by pooling the nodes to perform joint transmission/reception. In this paper, we consider the problem of optimally selecting a subset of nodes from potentially a large number of candidates to form a virtual multi-antenna system, while at the same time designing their joint linear transmission strategies. We focus on two specific application scenarios: 1) multiple single antenna transmitters cooperatively transmit to a receiver; 2) a single transmitter transmits to a receiver with the help of a number of cooperative relays. We …

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More Thoughts On Microsoft, David R. King Sep 2013

More Thoughts On Microsoft, David R. King

David King

The analysis examining “The case of Microsoft’s Surface Tablet” was developed in the Spring of 2013, but the predictive ability of SWOT analysis is borne out by current events with Steve Ballmer announcing his retirement and Microsoft’s purchase of Nokia’s mobile division. The purchase of Nokia’s mobile division was enabled by the financial assets of Microsoft highlighted by the article, and it fills two strategic needs.

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Aerodynamic Simulation Of Vertical-Axis Wind Turbines, A. Korobenko, Ming-Chen Hsu, I. Akkerman, Y. Bazilevs Sep 2013

Aerodynamic Simulation Of Vertical-Axis Wind Turbines, A. Korobenko, Ming-Chen Hsu, I. Akkerman, Y. Bazilevs

Ming-Chen Hsu

Full-scale, 3D, time-dependent aerodynamics modeling and simulation of a Darrieus-type vertical-axis wind turbine (VAWT) is presented. The simulations are performed using a moving-domain finite-element-based ALE-VMS technique augmented with a sliding-interface formulation to handle the rotor-stator interactions present. We simulate a single VAWT using a sequence of meshes with increased resolution to assess the computational requirements for this class of problems. The computational results are in good agreement with experimental data. We also perform a computation of two side-by-side counterrotating VAWTs to illustrate how the ALE-VMS technique may be used for the simulation of multiple turbines placed in arrays.

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A Divalent Protecting Group For Benzoxaboroles, Brett Vanveller, Matthew R. Aronoff, Ronald T. Raines Sep 2013

A Divalent Protecting Group For Benzoxaboroles, Brett Vanveller, Matthew R. Aronoff, Ronald T. Raines

Brett VanVeller

1-Dimethylamino-8-methylaminonaphthalene is put forth as a protecting group for benzoxaboroles. The ensuing complex is fluorescent, charge-neutral, highly stable under basic conditions, stable to anhydrous acid, and readily cleavable in aqueous acid to return the free benzoxaborole.

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The Genome And Developmental Transcriptome Of The Strongylid Nematode Haemonchus Contortus, Erich M. Schwarz, Pasi K. Korhonen, Bronwyn E. Campbell, Neil D. Young, Aaron R. Jex, Abdul Jabbar, Ross S. Hall, Alinda Mondal, Adina C. Howe, Jason Pell, Andreas Hofmann, Peter R. Boag, Xing-Quan Zhu, T. Ryan Gregory, Alex Loukas, Brian A. Williams, Igor Antoshechkin, C. Titus Brown, Paul W. Sternberg, Robin B. Gasser Aug 2013

The Genome And Developmental Transcriptome Of The Strongylid Nematode Haemonchus Contortus, Erich M. Schwarz, Pasi K. Korhonen, Bronwyn E. Campbell, Neil D. Young, Aaron R. Jex, Abdul Jabbar, Ross S. Hall, Alinda Mondal, Adina C. Howe, Jason Pell, Andreas Hofmann, Peter R. Boag, Xing-Quan Zhu, T. Ryan Gregory, Alex Loukas, Brian A. Williams, Igor Antoshechkin, C. Titus Brown, Paul W. Sternberg, Robin B. Gasser

Adina Howe

Background The barber's pole worm, Haemonchus contortus, is one of the most economically important parasites of small ruminants worldwide. Although this parasite can be controlled using anthelmintic drugs, resistance against most drugs in common use has become a widespread problem. We provide a draft of the genome and the transcriptomes of all key developmental stages of H. contortus to support biological and biotechnological research areas of this and related parasites. Results The draft genome of H. contortus is 320 Mb in size and encodes 23,610 protein-coding genes. On a fundamental level, we elucidate transcriptional alterations taking place throughout the life …

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Paramagnetic Ionic Liquids For Measurements Of Density Using Magnetic Levitation, David K. Bwambok, Martin M. Thuo, Manza B.J. Atkinson, Katherine A. Mirica, Nathan D. Shapiro, George M. Whitesides Aug 2013

Paramagnetic Ionic Liquids For Measurements Of Density Using Magnetic Levitation, David K. Bwambok, Martin M. Thuo, Manza B.J. Atkinson, Katherine A. Mirica, Nathan D. Shapiro, George M. Whitesides

Martin M. Thuo

Paramagnetic ionic liquids (PILs) provide new capabilities to measurements of density using magnetic levitation (MagLev). In a typical measurement, a diamagnetic object of unknown density is placed in a container containing a PIL. The container is placed between two magnets (typically NdFeB, oriented with like poles facing). The density of the diamagnetic object can be determined by measuring its position in the magnetic field along the vertical axis (levitation height, h), either as an absolute value or relative to internal standards of known density. For density measurements by MagLev, PILs have three advantages over solutions of paramagnetic salts in aqueous …

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Iron Oxidation Stimulates Organic Matter Decomposition In Humid Tropical Forest Soils, Steven J. Hall, Whendee L. Silver Jul 2013

Iron Oxidation Stimulates Organic Matter Decomposition In Humid Tropical Forest Soils, Steven J. Hall, Whendee L. Silver

Steven J. Hall

Humid tropical forests have the fastest rates of organic matter decomposition globally, which often coincide with fluctuating oxygen (O2) availability in surface soils. Microbial iron (Fe) reduction generates reduced iron [Fe(II)] under anaerobic conditions, which oxidizes to Fe(III) under subsequent aerobic conditions. We demonstrate that Fe (II) oxidation stimulates organic matter decomposition via two mechanisms: (i) organic matter oxidation, likely driven by reactive oxygen species; and (ii) increased dissolved organic carbon (DOC) availability, likely driven by acidification. Phenol oxidative activity increased linearly with Fe(II) concentrations (P < 0.0001, pseudo R2 = 0.79) in soils sampled within and among five tropical forest sites. A similar pattern occurred in the absence of soil, suggesting an abiotic driver of this reaction. No phenol oxidative activity occurred in soils under anaerobic conditions, implying the importance of oxidants such as O2 or hydrogen peroxide (H2O2) in addition to Fe(II). Reactions between Fe(II) and H2O2 generate hydroxyl radical, a strong nonselective oxidant of organic compounds. We found increasing consumption of H2O2 as soil Fe(II) concentrations increased, suggesting that reactive oxygen species produced by Fe(II) oxidation explained variation in phenol oxidative activity among samples. Amending soils with Fe(II) at field concentrations stimulated short-term C mineralization by up to 270%, likely via a second mechanism. Oxidation of Fe(II) drove a decrease in pH and a monotonic increase in DOC; a decline of two pH units doubled DOC, likely stimulating microbial respiration. We obtained similar results by manipulating soil acidity independently of Fe(II), implying that Fe(II) oxidation affected C substrate availability via pH fluctuations, in addition to producing reactive oxygen species. Iron oxidation coupled to organic matter decomposition contributes to rapid rates of C cycling across humid tropical forests in spite of periodic O2 limitation, and may help explain the rapid turnover of complex C molecules in these soils.

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Joint Access Point Selection And Power Allocation For Uplink Wireless Networks, Mingyi Hong, Alfredo Garcia, Jorge Barrera, Stephen G. Wilson Jul 2013

Joint Access Point Selection And Power Allocation For Uplink Wireless Networks, Mingyi Hong, Alfredo Garcia, Jorge Barrera, Stephen G. Wilson

Mingyi Hong

We consider the distributed uplink resource allocation problem in a multi-carrier wireless network with multiple access points (APs). Each mobile user can optimize its own transmission rate by selecting a suitable AP and by controlling its transmit power. Our objective is to devise suitable algorithms by which mobile users can jointly perform these tasks in a distributed manner. Our approach relies on a game theoretic formulation of the joint power control and AP selection problem. In the proposed game, each user is a player with an associated strategy containing a discrete variable (the AP selection decision) and a continuous vector …

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Covalent Immobilization Of Lysozyme On Ethylene Vinyl Alcohol Films For Nonmigrating Antimicrobial Packaging Applications, V. Muriel-Galet, Joey N. Talbert, P. Hernandez-Munoz, R. Gavara, J. M. Goddard Jun 2013

Covalent Immobilization Of Lysozyme On Ethylene Vinyl Alcohol Films For Nonmigrating Antimicrobial Packaging Applications, V. Muriel-Galet, Joey N. Talbert, P. Hernandez-Munoz, R. Gavara, J. M. Goddard

Joey Talbert

The objective of this study was to develop a new antimicrobial film, in which lysozyme was covalently attached onto two different ethylene vinyl alcohol copolymers (EVOH 29 and EVOH 44). The EVOH surface was modified with UV irradiation treatment to generate carboxylic acid groups, and lysozyme was covalently attached to the functionalized polymer surface. Surface characterization of control and modified films was performed using attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and dye assay. The value of protein loading after attachment on the surface was 8.49 μg protein/cm2 and 5.74 μg protein/cm2 for EVOH 29 and EVOH 44, respectively, …

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Adults With Greater Weight Satisfaction Report More Positive Health Behaviors And Have Better Health Status Regardless Of Bmi, Christine E. Blake, James R. Hebert, Duck-Chul Lee, Swann A. Adams, Susan E. Steck, Xuemei Sui, Jennifer L. Kuk, Meghan Baruth, Steven N. Blair Jun 2013

Adults With Greater Weight Satisfaction Report More Positive Health Behaviors And Have Better Health Status Regardless Of Bmi, Christine E. Blake, James R. Hebert, Duck-Chul Lee, Swann A. Adams, Susan E. Steck, Xuemei Sui, Jennifer L. Kuk, Meghan Baruth, Steven N. Blair

Duck-Chul Lee

Background. Prior studies suggest that weight satisfaction may preclude changes in behavior that lead to healthier weight among individuals who are overweight or obese. Objective. To gain a better understanding of complex relationships between weight satisfaction, weight-related health behaviors, and health outcomes. Design. Cross-sectional analysis of data from the Aerobics Center Longitudinal Study (ACLS). Participants. Large mixed-gender cohort of primarily white, middle-to-upper socioeconomic status (SES) adults with baseline examination between 1987 and 2002 (𝑛 19,003). Main Outcome Variables. Weight satisfaction, weight-related health behaviors, chronic health conditions, and clinical health indicators. Statistical Analyses Performed. Chi-square test, t-tests, and linear and multivariate …

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Effect Of Continued Nitrogen Enrichment On Greenhouse Gas Emissions From A Wetland Ecosystem In The Sanjiang Plain, Northeast China: A 5 Year Nitrogen Addition Experiment, Changchun Song, Lili Wang, Hanqin Tian, Deyan Liu, Chaoqun (Crystal) Lu, Xiaofeng Xu, Lihua Zhang, Guisheng Yang, Zhongmei Wan Jun 2013

Effect Of Continued Nitrogen Enrichment On Greenhouse Gas Emissions From A Wetland Ecosystem In The Sanjiang Plain, Northeast China: A 5 Year Nitrogen Addition Experiment, Changchun Song, Lili Wang, Hanqin Tian, Deyan Liu, Chaoqun (Crystal) Lu, Xiaofeng Xu, Lihua Zhang, Guisheng Yang, Zhongmei Wan

Chaoqun (Crystal) Lu

Mounting evidence supports that wetland ecosystems, one of the largest carbon pools on the earth, are exposed to ample nitrogen (N) additions due to atmospheric deposition or N loading from upstream agricultural fertilizer application. However, our understanding of how N enrichment affects the fluxes of greenhouse gases (GHGs) in wetlands is weak. A 5 year N addition experiment was conducted to examine the responses of CH4 and N2O fluxes as well as ecosystem respiration from wetlands in the Sanjiang Plain, Northeast China, through 2005 to 2009. Four levels of N addition (control, 0 kg N ha−1 yr−1; low-level, 60 kg …

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Distributed Linear Precoder Optimization And Base Station Selection For An Uplink Heterogeneous Network, Mingyi Hong, Zhi-Quan Luo Jun 2013

Distributed Linear Precoder Optimization And Base Station Selection For An Uplink Heterogeneous Network, Mingyi Hong, Zhi-Quan Luo

Mingyi Hong

In a heterogeneous wireless cellular network, each user may be covered by multiple access points such as macro/pico/relay/femto base stations (BS). An effective approach to maximize the sum utility (e.g., system throughput) in such a network is to jointly optimize users' linear procoders as well as their BS associations. In this paper, we first show that this joint optimization problem is NP-hard and thus is difficult to solve to global optimality. To find a locally optimal solution, we formulate the problem as a noncooperative game in which the users and the BSs both act as players. We introduce a set …

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N→Π* Interactions Of Amides And Thioamides: Implications For Protein Stability, Robert W. Newberry, Brett Vanveller, Ilia A. Guzei, Ronald T. Raines May 2013

N→Π* Interactions Of Amides And Thioamides: Implications For Protein Stability, Robert W. Newberry, Brett Vanveller, Ilia A. Guzei, Ronald T. Raines

Brett VanVeller

Carbonyl–carbonyl interactions between adjacent backbone amides have been implicated in the conformational stability of proteins. By combining experimental and computational approaches, we show that relevant amidic carbonyl groups associate through an n→π* donor–acceptor interaction with an energy of at least 0.27 kcal/mol. The n→π* interaction between two thioamides is 3-fold stronger than between two oxoamides due to increased overlap and reduced energy difference between the donor and acceptor orbitals. This result suggests that backbone thioamide incorporation could stabilize protein structures. Finally, we demonstrate that intimate carbonyl interactions are described more completely as donor–acceptor orbital interactions rather than dipole–dipole interactions.

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House Finch Populations Differ In Early Inflammatory Signaling And Pathogen Tolerance At The Peak Of Mycoplasma Gallisepticum Infection, James S. Adelman, Laila Kirkpatrick, Jessica L. Grodio, Dana M. Hawley May 2013

House Finch Populations Differ In Early Inflammatory Signaling And Pathogen Tolerance At The Peak Of Mycoplasma Gallisepticum Infection, James S. Adelman, Laila Kirkpatrick, Jessica L. Grodio, Dana M. Hawley

James S. Adelman

Host individuals and populations often vary in their responses to infection, with direct consequences for pathogen spread and evolution. While considerable work has focused on the mechanisms underlying differences in resistance—the ability to kill pathogens— we know little about the mechanisms underlying tolerance— the ability to minimize fitness losses per unit pathogen. Here, we examine patterns and mechanisms of tolerance between two populations of house finches (Haemorhous [formerly Carpodacus] mexicanus) with different histories with the bacterial pathogen Mycoplasma gallisepticum (MG). After infection in a common environment, we assessed two metrics of pathology, mass loss and eye lesion severity, as proxies …

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Extremes Of Nonlinear Vibration: Comparing Models Based On Moments, L-Moments, And Maximum Entropy, Steven R. Winterstein, Cameron A. Mackenzie May 2013

Extremes Of Nonlinear Vibration: Comparing Models Based On Moments, L-Moments, And Maximum Entropy, Steven R. Winterstein, Cameron A. Mackenzie

Cameron A. MacKenzie

Wind and wave loads on offshore structures show nonlinear effects, which require nonGaussian statistical models. Here we critically review the behavior of various nonGaussian models. We first survey moment-based models; in particular, the four-moment “Hermite” model, a cubic transformation often used in wind and wave applications. We then derive an “L-Hermite” model, an alternative cubic transformation calibrated by the response “L-moments” rather than its ordinary statistical moments. These L-moments have recently found increasing use, in part because they show less sensitivity to distribution tails than ordinary moments. We find here, however, that these L-moments may not convey sufficient information to …

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Safety Impacts Of Signal-Warning Flashers And Speed Control At High-Speed Signalized Intersections, Zifeng Wu, Anuj Sharma, Fred L. Mannering, Shefang Wang May 2013

Safety Impacts Of Signal-Warning Flashers And Speed Control At High-Speed Signalized Intersections, Zifeng Wu, Anuj Sharma, Fred L. Mannering, Shefang Wang

Anuj Sharma

For many years, to reduce the crash frequency and severity at high-speed signalized intersections, warning flashers have been used to alert drivers of potential traffic-signal changes. Recently, more aggressive countermeasures at such intersections include a speed-limit reduction in addition to warning flashers. While such speed-control strategies have the potential to further improve the crash-mitigation effectiveness of warning flashers, a rigorous statistical analysis of crash data from such intersections has not been undertaken to date. This paper uses 10-year crash data from 28 intersections in Nebraska (all with intersection approaches having signal-warning flashers; some with no speed-limit reduction, and the others …

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Enterobacter-Activated Mosquito Immune Responses To Plasmodium Involve Activation Of Srpn6 In Anopheles Stephensi, Ryan C. Smith, Abraham G. Eappen, Marcelo Jacobs-Lorena May 2013

Enterobacter-Activated Mosquito Immune Responses To Plasmodium Involve Activation Of Srpn6 In Anopheles Stephensi, Ryan C. Smith, Abraham G. Eappen, Marcelo Jacobs-Lorena

Ryan C. Smith

Successful development of Plasmodium in the mosquito is essential for the transmission of malaria. A major bottleneck in parasite numbers occurs during midgut invasion, partly as a consequence of the complex interactions between the endogenous microbiota and the mosquito immune response. We previously identified SRPN6 as an immune component which restricts Plasmodium berghei development in the mosquito. Here we demonstrate that SRPN6 is differentially activated by bacteria in Anopheles stephensi, but only when bacteria exposure occurs on the lumenal surface of the midgut epithelium. Our data indicate that AsSRPN6 is strongly induced following exposure to Enterobacter cloacae, a common component …

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55 Years Old With A 33 Year Library Career: What Now?, Kathy A. Parsons Apr 2013

55 Years Old With A 33 Year Library Career: What Now?, Kathy A. Parsons

Kathy A. Parsons

After reading the July 2012 Will’s World column “Your Mileage May Vary” in American Libraries, I found myself pondering about library fatigue, retirement, and the value of what I do for a living. In 2013, I will be 55 with 33 years of experience in libraries. Was I that librarian that needed to retire? I sincerely hope not but I saw a large part of myself in those statements. But part of me was still that person who could embrace technology changes and find fun in the everyday tasks. Was library fatigue taking over? Could I reverse “the odometer” and …

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Finite Element Simulation Of Wind Turbine Aerodynamics: Validation Study Using Nrel Phase Vi Experiment, Ming-Chen Hsu, Ido Akkerman, Yuri Bazilevs Mar 2013

Finite Element Simulation Of Wind Turbine Aerodynamics: Validation Study Using Nrel Phase Vi Experiment, Ming-Chen Hsu, Ido Akkerman, Yuri Bazilevs

Ming-Chen Hsu

A validation study using the National Renewable Energy Laboratory (NREL) Phase VI wind turbine is presented. The aerodynamics simulations are performed using the finite element arbitrary Lagrangian–Eulerian–variational multiscale formulation augmented with weakly enforced essential boundary conditions. In all cases, the rotor is assumed to be rigid and its rotation is prescribed. The rotor-only simulations are performed for a wide range of wind conditions, and the computational results compare favorably with the experimental findings in all cases. The sliding-interface method is adopted for the simulation of the full wind turbine configuration. The full-wind-turbine simulations capture the blade–tower interaction effect, and the …

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Medial Knee Joint Loading During Stair Ambulation And Walking While Carrying Loads, M. Hall, Jason C. Gillette, G. A. Mirka Mar 2013

Medial Knee Joint Loading During Stair Ambulation And Walking While Carrying Loads, M. Hall, Jason C. Gillette, G. A. Mirka

Jason C Gillette

Carrying loads while walking or using stairs is a common activity of daily living. Knee osteoarthritis is associated with increased external knee adduction moment (KAM) during walking, so understanding how the additional challenges of stairs and carrying loads impact these moments is of value. Sixteen healthy individuals performed three types of MOTION (walking, stair ascent, stair descent) under three LOAD conditions (no load, carrying a 13.6kg front load, carrying 13.6kg load in a backpack). Three-dimensional gait analysis was used to measure KAM. Results of ANOVA showed a significant main effect of both MOTION and LOAD on peak KAM (p<0.001), but no significant MOTION×LOAD interaction (p=0.250). Peak KAM during stair ascent was about two-times those seen in stair descent (p<0.001) and was significantly higher than those seen in walking (p<0.001). Conditions with LOAD generated significantly greater KAM as compared to the no-LOAD conditions (p<0.001). These findings suggest that carrying a load of moderate magnitude while climbing stairs significantly increases the peak KAM - a risk factor associated with knee osteoarthritis.

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Educational Needs Asessment And Practices Of Grocery Store Food Handlers Through Survey And Observational Data Collection, Lynn A. Robertson, Renee R. Boyer, Benjamin J. Chapman, Joseph D. Eifert, Nancy K. Franz Mar 2013

Educational Needs Asessment And Practices Of Grocery Store Food Handlers Through Survey And Observational Data Collection, Lynn A. Robertson, Renee R. Boyer, Benjamin J. Chapman, Joseph D. Eifert, Nancy K. Franz

Nancy K. Franz

Grocery store associates in deli/bakery departments prepare and serve an increasing number of ready-to eat (RTE) foods and full meals. The shift to more convenience foods and take-home meals highlights the need for effective food safety training programs in retail grocery establishments to prevent foodborne illness. Through qualitative and quantitative methods, food safety knowledge, training preferences, needs, and current practices of grocery stores deli/bakery food handlers in Southwest and Southern Virginia were explored. Deli employees (n ¼ 78) completed a 34 question survey eliciting information on demographics, food safety training needs, preferences and knowledge. In an additional phase of this …

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Blended Isogeometric Shells, D. J. Benson, S. Hartmann, Y. Bazilevs, Ming-Chen Hsu, T.J.R. Hughes Mar 2013

Blended Isogeometric Shells, D. J. Benson, S. Hartmann, Y. Bazilevs, Ming-Chen Hsu, T.J.R. Hughes

Ming-Chen Hsu

We propose a new isogeometric shell formulation that blends Kirchhoff–Love theory with Reissner–Mindlin theory. This enables us to reduce the size of equation systems by eliminating rotational degrees of freedom while simultaneously providing a general and effective treatment of kinematic constraints engendered by shell intersections, folds, boundary conditions, the merging of NURBS patches, etc. We illustrate the blended theory’s performance on a series of test problems.

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Into The Breach: The Career Of David B. Gracy Ii, Kimberly D. Anderson Mar 2013

Into The Breach: The Career Of David B. Gracy Ii, Kimberly D. Anderson

Kimberly D. Anderson

David B. Gracy II has had a significant influence on the development of archival practice in the United States. Through his service in and leadership of the Society of American Archivists, and his activism regionally in both Texas and Georgia, Gracy has shaped the profession and inspired several generations of students and future archivists. This paper explores the development of Gracy’s career and the impact it has had on archives, archivists, and the field of archival enterprise.

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Structural Health Monitoring System And Method Using Soft Capacitive Sensing Materials, Simon Laflamme, Matthias Kollosche, Guggi H. R. Kofod Feb 2013

Structural Health Monitoring System And Method Using Soft Capacitive Sensing Materials, Simon Laflamme, Matthias Kollosche, Guggi H. R. Kofod

Simon Laflamme

A structural health monitoring system is provided to diagnose and localize crack damage on structural elements. The system uses one or more capacitive sensor assemblies that employ a soft dielectric material. The system can be applied over a large area as a sensing skin, allowing the presence of cracks to be localized.

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45-Year Trends In Women's Use Of Time And Household Management Energy Expenditure., Edward Archer, Robin P. Shook, Diana M. Thomas, Timothy S. Church, Peter T. Katzmarzyk, James R. Hebert, Kerry L. Mciver, Gregory A. Hand, Carl J. Lavie, Steven N. Blair Feb 2013

45-Year Trends In Women's Use Of Time And Household Management Energy Expenditure., Edward Archer, Robin P. Shook, Diana M. Thomas, Timothy S. Church, Peter T. Katzmarzyk, James R. Hebert, Kerry L. Mciver, Gregory A. Hand, Carl J. Lavie, Steven N. Blair

Robin Shook

Context: Relationships between socio-environmental factors and obesity are poorly understood due to a dearth of longitudinal population-level research. The objective of this analysis was to examine 45-year trends in time-use, household management (HM) and energy expenditure in women. Design and Participants: Using national time-use data from women 19–64 years of age, we quantified time allocation and household management energy expenditure (HMEE) from 1965 to 2010. HM was defined as the sum of time spent in food preparation, post-meal cleaning activities (e.g., dish-washing), clothing maintenance (e.g., laundry), and general housework. HMEE was calculated using body weights from national surveys and metabolic …

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