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Estrogen And Hippocampal Plasticity In Rodent Models, Michael R. Foy, Michel Baudry, Roberta Diaz Brinton, Richard F. Thompson
Estrogen And Hippocampal Plasticity In Rodent Models, Michael R. Foy, Michel Baudry, Roberta Diaz Brinton, Richard F. Thompson
Psychological Science Faculty Works
Accumulating evidence indicates that ovarian hormones regulate a wide variety of non-reproductive functions in the central nervous system by interacting with several molecular and cellular processes. A growing animal literature using both adult and aged rodent models indicates that 17β-estradiol, the most potent of the biologically relevant estrogens, facilitates some forms of learning and memory, in particular those that involve hippocampal-dependent tasks. A recently developed triple-transgenic mouse (3xTg-AD) has been widely used as an animal model of Alzheimer's disease, as this mouse exhibits an age-related and progressive neuropathological phenotype that includes both plaque and tangle pathology mainly restricted to hippocampus, …
Attitudes Towards One’S Aging Among Single, Professional, Highly Educated, Baby Boom Women: “I Don’T Know Who I Am, But I Am Not A Crazy Old Maid!”, Tatyana Shepel
Antioch University Dissertations & Theses
Age is a value-laden cultural construct as it conveys social attitudes toward aging. This qualitative research, using a grounded theory approach and critical feminist gerontology as a theoretical framework, makes visible the experience of growing older and the renegotiation of self-identity among the ten single, professional, highly educated women ages 47-59 who resided in the Pacific Northwest and lets their voices be heard. In this study ten in-depth interviews and one focus group provided narrative data that captured women’s experiences of aging and uncovered common themes. The explored phenomenon of aging is experienced in the various socio-cultural contexts and conditions …