Digital Commons Network^™

Tavr In Older Adults: Moving Toward A Comprehensive Geriatric Assessment And Away From Chronological Age, Abdulla A Damluji, Gwen Bernacki, Jonathan Afilalo, Radmila Lyubarova, Ariela R Orkaby, Min Ji Kwak, Scott Hummel, James N Kirkpatrick, Mathew S Maurer, Nanette Wenger, Michael W Rich, Dae Hyun Kim, Roberta Y Wang, Daniel E Forman, Ashok Krishnaswami

Journal Articles

Calcific aortic stenosis can be considered a model for geriatric cardiovascular conditions due to a confluence of factors. The remarkable technological development of transcatheter aortic valve replacement was studied initially on older adult populations with prohibitive or high-risk for surgical valve replacement. Through these trials, the cardiovascular community has recognized that stratification of these chronologically older adults can be improved incrementally by invoking the concept of frailty and other geriatric risks. Given the complexity of the aging process, stratification by chronological age should only be the initial step but is no longer sufficient to optimally quantify cardiovascular and noncardiovascular risk. …

An Ewas Of Dementia Biomarkers And Their Associations With Age, African Ancestry, And Ptsd, Mark W. Miller, Erika J. Wolf, Xiang Zhao, Mark W. Logue, Sage E. Hawn

Psychology Faculty Publications

Background

Large-scale cohort and epidemiological studies suggest that PTSD confers risk for dementia in later life but the biological mechanisms underlying this association remain unknown. This study examined this question by assessing the influences of PTSD, APOE ε4 genotypes, DNA methylation, and other variables on the age- and dementia-associated biomarkers Aβ40, Aβ42, GFAP, NfL, and pTau-181 measured in plasma. Our primary hypothesis was that PTSD would be associated with elevated levels of these markers.

Methods

Analyses were based on data from a PTSD-enriched cohort of 849 individuals. We began by performing factor analyses of the biomarkers, the results of which …

Moving Beyond Fulfillment: Wisdom Years Stories Of Passion, Perseverance, And Productivity, Kenneth A. Kiewra, Jessica Walsh, Chris Labenz

Department of Educational Psychology: Faculty Publications

Seven participants were interviewed to uncover how they remain so productive in their wisdom years, those typically marked by retirement. Participants included a leading educational psychologist, a renowned national television news anchor, a four-time national champion collegiate coach, the founder and former chief executive of Arbor Day Foundation, a university scholar turned playwright, and two female adventurers who quit their jobs, sold their possessions, and have lived a nomadic life, hiking thousands of miles throughout America. Their wisdom years stories describe how and why they shun retirement and remain productive. The article concludes with seven advice-laden conclusions for readers: (a) …

Editorial: Exploring The Technological Needs Of Older Adults: Advances In Design, Functionality, User Experience, And Age-Related Cognitive And Sensory Aids To Facilitate Adoption, Alex Chaparro, Cristina Cachero, Joanne M. Wood

Publications

The rapid advancements in artificial intelligence, robotics, communication, and automation have been the catalyst for the development of a host of new technologies that allow older users to monitor their own health (via wearables), maintain their independence (semi-autonomous driving), social connections (smart home devices), and compensate for a range of age-related sensory changes (hearing aids, smart glasses, augmented displays, etc.). Less well understood is how older users get acquainted with these innovations, how their design and functionality need to be adapted to improve older users’ performance and experience, and which factors and interventions help or hinder technology adoption and use …

Family History Of Fxtas Is Associated With Age-Related Cognitive-Linguistic Decline Among Mothers With The Fmr1 Premutation, Jessica Klusek, Amanda Fairchild, Carly Moser, Marsha R. Mailick, Angela John Thurman, Leonard Abbeduto

Faculty Publications

BACKGROUND: Women who carry a premutation allele of the FMR1 gene are at increased vulnerability to an array of age-related symptoms and disorders, including age-related decline in select cognitive skills. However, the risk factors for age-related decline are poorly understood, including the potential role of family history and genetic factors. In other forms of pathological aging, early decline in syntactic complexity is observed and predicts the later onset of neurodegenerative disease. To shed light on the earliest signs of degeneration, the present study characterized longitudinal changes in the syntactic complexity of women with the FMR1 premutation across midlife, and associations …

Mitochondrial Phenotypes In Purified Human Immune Cell Subtypes And Cell Mixtures, Shannon Rausser, Caroline Trumpff, Marlon A. Mcgill, Alex Junker, Wei Wang, Siu-Hong Ho, Anika Mitchell, Kalpita R. Karan, Catherine Monk, Suzanne C. Segerstrom, Rebecca G. Reed, Martin Picard

Psychology Faculty Publications

Using a high-throughput mitochondrial phenotyping platform to quantify multiple mitochondrial features among molecularly defined immune cell subtypes, we quantify the natural variation in mitochondrial DNA copy number (mtDNAcn), citrate synthase, and respiratory chain enzymatic activities in human neutrophils, monocytes, B cells, and naïve and memory T lymphocyte subtypes. In mixed peripheral blood mononuclear cells (PBMCs) from the same individuals, we show to what extent mitochondrial measures are confounded by both cell type distributions and contaminating platelets. Cell subtype-specific measures among women and men spanning four decades of life indicate potential age- and sex-related differences, including an age-related elevation in mtDNAcn, …

Assessing Preference And Stability Of Preference For Individuals With Neurocognitive Disorder, Megan N. Ford, Makenzie W. Bayles, Jennifer L. Bruzek

Research, Publications & Creative Work

Poor engagement can lead to a reduced quality of life for individuals with neurocognitive disorder (NCD). Research on determining preference and increasing engagement with this population is limited. The purpose of this study was to compare the accuracy of four preference assessment formats in identifying preferred activities and predicting engagement for six females with NCD and to measure the stability of preference and engagement over time. We compared the predictability of single stimulus(SS) verbal and multimedia assessments, caregiver ranking (CR) assessments, and multiple-stimulus without-replacement (MSWO) assessments. Participants responded consistently on SS assessments, but we noted inconsistencies between the CR and …

Driving Habits, Cognition, And Health-Related Quality Of Life In Middle-Aged And Older Adults With Hiv, Josiah J. Robinson, Tess Walker, Cierra Hopkins, Brittany Bradley, Peggy Mckie, Jennifer S. Frank, Caitlin N. Pope, Pariya L. Fazeli, David E. Vance

Graduate Center for Gerontology Faculty Publications

Cognitive impairment is known to increase with aging in people living with HIV (PLWH). Impairment in cognitive domains required for safe driving may put PLWH at risk for poor driving outcomes, decreased mobility, and health-related quality of life (HRQoL). This study described the driving behaviors of middle-aged and older PLWH and examined correlations between driving behaviors and cognitive functioning (Aim 1), and driving behaviors and HRQoL domains (Aim 2). A sample of 260 PLWH ages 40 and older completed a comprehensive assessment including a battery of cognitive tests, an HRQoL measure, and a measure of self-reported driving habits. Associations between …

Do Emotion Words Influence Age Effects In Delayed Match-To-Sample Performance For Emotional Faces?, Ying-Han Li

Masters Theses & Specialist Projects

Age differences are apparent in using verbal labels of emotion to categorize emotion face stimuli. Particularly, older adults have more difficulty detecting emotion cues like anger and fear relative to younger adults, but seem to have less difficulty with disgust cues. However, age differences are diminished in situations when participants are limited to two possible emotion choices or are required to simply match stimuli based on emotion cues without the use of labels. One question that emerges from the disparities in these findings is the role that emotion labels themselves play in driving possible age differences in emotion perception. The …

Binge Eating Among Older Women: Prevalence Rates And Health Correlates Across Three Independent Samples, Salomé A. Wilfred, Carolyn Black Becker, K. E. Kanzler, N. Musi, S. E. Espinoza, Lisa S. Kilpela

Psychology Faculty Research

Background: Emerging research indicates that binge eating (BE; consuming unusually large amounts of food in one siting while feeling a loss of control) is prevalent among older women. Yet, health correlates of BE in older adult populations are poorly understood. The original study aimed to investigate BE prevalence, frequency, and health correlates in a sample of older adult women. Based on results from this first study, we then sought to replicate findings in two additional samples of older adult women from separate studies.

Method: Using self-reported frequencies of BE from three separate samples of older women with very different demographics, …

The Role Of Alexithymia In Memory And Executive Functioning Across The Lifespan, Anthony N. Correro, Elizabeth Rose Paitel, Steven J. Byers, Kristy A. Nielson

Psychology Faculty Research and Publications

Alexithymia is a personality trait characterised by difficulties identifying feelings (DIF), describing feelings (DDF), and externally oriented thinking (EOT). Alexithymia has been associated with poorer memory, at least for emotive materials, and recently, with executive and neural dysfunction. Aging is also accompanied by poorer memory and executive functioning (EF), neural dysfunction, and increasing alexithymia. Thus, the hypothesis of a general cognitive impairment in alexithymia, particularly in elders, needs investigation. Three large, independent, cross-sectional experiments (n = 296, 139 and 121, respectively) investigated memory and EF in healthy adults, ranging from young to old adulthood, with age, sex, and the …

An Interpretative Phenomenological Analysis Of Older Adults And Subjective Well-Being, Averie A. Zdon

Antioch University Full-Text Dissertations & Theses

Older adults are rapidly aging. It is estimated that by 2030, 1 in every 5 adults will be 65 years old or older (Administration on Aging, 2018). With this increase will undoubtedly come an increase in older people seeking mental health services. It is paramount the field of psychology attempt to prepare for this increase by better understanding older persons. Subjective well-being (SWB) is a popular construct with a vast body of literature as it pertains to a variety of diverse people. However, there has been little research on SWB as it pertains to older adults. This study examined the …

Outdoor Air Pollution Exposure And Inter-Relation Of Global Cognitive Performance And Emotional Distress In Older Women, Andrew J. Petkus, Xinhui Wang, Daniel P. Beavers, Helena C. Chui, Mark A. Espeland, Margaret Gatz, Tara Gruenewald, Joel D. Kaufman, Joann E. Manson, Susan M. Resnick, James D. Stewart, Gregory A. Wellenius, Eric A. Whitsel, Keith Widaman, Diana Younan, Jiu-Chiuan Chen

Psychology Faculty Articles and Research

The interrelationships among long-term ambient air pollution exposure, emotional distress and cognitive decline in older adulthood remain unclear. Long-term exposure may impact cognitive performance and subsequently impact emotional health. Conversely, exposure may initially be associated with emotional distress followed by declines in cognitive performance. Here we tested the inter-relationship between global cognitive ability, emotional distress, and exposure to PM2.5 (particulate matter with aerodynamic diameter 2 (nitrogen dioxide) in 6118 older women (aged 70.6 ± 3.8 years) from the Women’s Health Initiative Memory Study. Annual exposure to PM_2.5 (interquartile range [IQR] = 3.37 μg/m³) and NO₂ (IQR …

Age-Related Losses In Cardiac Autonomic Activity During A Daytime Nap, Pin-Chun Chen, Negin Sattari, Lauren N. Whitehurst, Sara C. Mednick

Psychology Faculty Publications

In healthy, young individuals, a reduction in cardiovascular output and a shift from sympathetic to parasympathetic (vagal) dominance is observed from wake into stages of nocturnal and daytime sleep. This cardiac autonomic profile, measured by heart rate variability (HRV), has been associated with significant benefits for cardiovascular health. Aging is associated with decreased nighttime sleep quality and lower parasympathetic activity during both sleep and resting. However, it is not known whether age-related dampening of HRV extends to daytime sleep, diminishing the cardiovascular benefits of naps in the elderly. Here, we investigated this question by comparing the autonomic activity profile between …

The Effects Of Aging On Attention In Associative Learning, Katie Wheeler

Masters Theses & Specialist Projects

In this study we investigated how aging affects attention to predictive and uncertain cues during associative learning. According to Mackintosh’s theory of predictiveness (1975), attention will be allocated to cues that most reliably predict an outcome. An opposing theory of uncertainty from Pearce and Hall (1980) suggest attention will be allocated to cues whose outcomes are uncertain. Although these theories are contradictory, both are well supported in the associative learning literature. There is evidence that young and older adults give more attention to cues that are predictive compared to nonpredictive cues (Mutter et al., 2019), and that young adults respond …

Psychosocial Factors Promoting Personal Growth Throughout Adulthood, Masahiro Toyama, Heather R. Fuller, Joel M. Hektner

Psychology Faculty Research

Personal growth is essential in the lives of adults of any age and is associated with a variety of well-being outcomes. Building on previous research on psychosocial factors associated with personal growth, the present study aimed to investigate whether and how psychosocial factors (including working, generativity, positive interpersonal relationships, and spirituality) could affect aging adults’ personal growth longitudinally. Using three waves of Midlife in the United States data from adults with baseline ages of 20–75, two-level hierarchical linear modeling analyses were conducted to examine the effects of psychosocial factors as well as age and gender on levels and trajectories of …

The Project Talent Twin And Sibling Study: Zygosity And New Data Collection, Carol A. Prescott, Ellen E. Walters, Thalida Em Arpawong, Catalina Zavala, Tara L. Gruenewald, Margaret Gatz

Psychology Faculty Articles and Research

The Project Talent Twin and Sibling (PTTS) study includes 4481 multiples and their 522 nontwin siblings from 2233 families. The sample was drawn from Project Talent, a U.S. national longitudinal study of 377,000 individuals born 1942–1946, first assessed in 1960 and representative of U.S. students in secondary school (Grades 9–12). In addition to the twins and triplets, the 1960 dataset includes 84,000 siblings from 40,000 other families. This design is both genetically informative and unique in facilitating separation of the ‘common’ environment into three sources of variation: shared by all siblings within a family, specific to twin-pairs, and associated with …

High-Resolution Spectral Sleep Analysis Reveals A Novel Association Between Slow Oscillations And Memory Retention In Elderly Adults, Makoto Kawai, Logan D. Scheider, Omer Linkovski, Joshua Jordan, Rosy Karna, Sophia Pirog, Isabelle Cotto, Casey Buck, William J. Giardino, Ruth O'Hara

Psychology | Faculty Scholarship

Objective: In recognition of the mixed associations between traditionally scored slow wave sleep and memory, we sought to explore the relationships between slow wave sleep, electroencephalographic (EEG) power spectra during sleep and overnight verbal memory retention in older adults.

Design, Setting, Participants, and Measurements: Participants were 101 adults without dementia (52% female, mean age 70.3 years). Delayed verbal memory was first tested in the evening prior to overnight polysomnography (PSG). The following morning, subjects were asked to recall as many items as possible from the same List (overnight memory retention; OMR). Partial correlation analyses examined the associations of delayed verbal …

Successfully Aging At Work Or Successfully Working While Aging? The Importance Of Older Workers' Psychological Well-Being, William P. Jimenez

Psychology Faculty Publications

Frank, 62, has been working at the same company for the past 32 years. His strong work ethic, subject-matter expertise, and continued excellent performance have saved him from several waves of layoffs and restructuring. Over the years Frank has become cynical. Gradually, many of Frank’s close colleagues were let go, and he has had difficulty connecting with newer employees. Although he is not particularly happy at his job, Frank is determined to continue working for his employer until at least 66, which is when he can start collecting Social Security benefits without penalty.

Cultural Variability In The Association Between Age And Well-Being: The Role Of Uncertainty Avoidance, Smaranda Lawrie, Kimin Eom, Daniela Moza, Alin Gavreliuc, Heejung S. Kim

Research Collection School of Social Sciences

Past research has found a mixed relationship between age and subjective well-being. The current research advances the understanding of these findings by incorporating a cultural perspective. We tested whether the relationship between age and well-being is moderated by uncertainty avoidance, a cultural dimension dealing with society’s tolerance for ambiguity. In Study 1 (N = 64,228), using a multilevel approach with an international database, we found that older age was associated with lower well-being in countries higher in uncertainty avoidance but not in countries lower in uncertainty avoidance. Further, this cultural variation was mediated by a sense of control. In Study …

The Effect Of Viewing Advertisements Depicting Information And Communication Technology On Older Adults' Technology Self-Efficacy, Hollie Brianne Coleman

Masters Theses & Specialist Projects

Information and communication technologies (ICTs) are an important part of society today. Older adults often report ICTs as difficult to use and unhelpful; however, ICTs can support older adults’ ability to stay in touch with family and friends across long distances and help increase their quality of life. Unfortunately, training programs targeted at teaching older adults to use ICTs are often costly and time-consuming. The current study attempts to determine whether advertisements depicting older adults using ICTs can be used to increase self-efficacy without the use of training programs.

A within subjects experimental design was completed using an independent variable …

Thirty-Five Years Of Computerized Cognitive Assessment Of Aging — Where Are We Now?, Avital Sternin, Alistair Burns, Adrian M. Owen

Brain and Mind Institute Researchers' Publications

Over the past 35 years, the proliferation of technology and the advent of the internet have resulted in many reliable and easy to administer batteries for assessing cognitive function. These approaches have great potential for affecting how the health care system monitors and screens for cognitive changes in the aging population. Here, we review these new technologies with a specific emphasis on what they offer over and above traditional ‘paper-and-pencil’ approaches to assessing cognitive function. Key advantages include fully automated administration and scoring, the interpretation of individual scores within the context of thousands of normative data points, the inclusion of …

Do Private Household Transfers To The Elderly Respond To Public Pension Benefits? Evidence From Rural China, Plamen Nikolov, Alan Adelman

Economics Faculty Scholarship

Aging populations in developing countries have spurred the introduction of public pension programs to preserve the standard of living for the elderly. The often-overlooked mechanism of intergenerational transfers, however, can dampen these intended policy effects, as adult children who make income contributions to their parents could adjust their behavior in response to changes in their parents’ income. Exploiting a unique policy intervention in China, we examine using a difference-in-difference-in-differences (DDD) approach how a new pension program impacts inter vivos transfers. We show that pension benefits lower the propensity of adult children to transfer income to elderly parents in the context …

The Influence Of Aging, Gaze Direction, And Context On Emotion Discrimination Performance, Alyssa Renee Minton

Masters Theses & Specialist Projects

This study examined how younger and older adults differ in their ability to discriminate between pairs of emotions of varying degrees of similarity when presented with an averted or direct gaze in either a neutral, congruent, or incongruent emotional context. For Task 1, participants were presented with three blocks of emotion pairs (i.e., anger/disgust, sadness/disgust, and fear/disgust) and were asked to indicate which emotion was being expressed. The actors’ gaze direction was manipulated such that emotional facial expressions were depicted with a direct gaze or an averted gaze. For Task 2, the same stimuli were placed into emotional contexts (e.g., …

Moderating Effect Of Cortical Thickness On Bold Signal Variability Age-Related Changes, Daiana R. Pur, Roy A. Eagleson, Anik De Ribaupierre, Nathalie Mella, Sandrine De Ribaupierre

Brain and Mind Institute Researchers' Publications

© Copyright © 2019 Pur, Eagleson, de Ribaupierre, Mella and de Ribaupierre. The time course of neuroanatomical structural and functional measures across the lifespan is commonly reported in association with aging. Blood oxygen-level dependent signal variability, estimated using the standard deviation of the signal, or “BOLDSD,” is an emerging metric of variability in neural processing, and has been shown to be positively correlated with cognitive flexibility. Generally, BOLDSD is reported to decrease with aging, and is thought to reflect age-related cognitive decline. Additionally, it is well established that normative aging is associated with structural changes in brain regions, and that …

Resting Cerebral Blood Flow After Exercise Training In Mild Cognitive Impairment, Alfonso J. Alfini, Lauren R. Weiss, Kristy A. Nielson, Matthew D. Verber, J. Carson Smith

Psychology Faculty Research and Publications

Background:

Exercise training has been associated with greater cerebral blood flow (CBF) in cognitively normal older adults (CN). Alterations in CBF, including compensatory perfusion in the prefrontal cortex, may facilitate changes to the brain’s neural infrastructure.

Objective:

To examine the effects of a 12-week aerobic exercise intervention on resting CBF and cognition in CN and those with mild cognitive impairment (MCI). We hypothesized individuals with MCI (vs. CN) would exhibit greater whole brain CBF at baseline and that exercise would mitigate these differences. We also expected CBF changes to parallel cognitive improvements.

Methods:

Before and after a 12-week exercise intervention, …

An Investigation Into The Impact Of Acute Stress On Encoding In Older Adults, Amy M. Smith, Katinka Dijkstra, Leamarie Gordon, L. Michael Romero, Ayanna K. Thomas

Psychology Department Faculty Works

Acute psychological stress commonly occurs in young and older adults’ lives. Though several studies have examined the influence of stress on how young adults learn new information, the present study is the first to directly examine these effects in older adults. Fifty older adults (M age = 71.9) were subjected to either stress induction or a control task before learning two types of information: a short video and a series of pictures. Twenty-four hours later, they were exposed to misleading information about the video and then completed memory tests for the video and pictures. Heart rate and cortisol measures …

Generational Perceptions Of Support Among Congolese Refugees In Urban Tanzania, Julie A. Tippens

Department of Child, Youth, and Family Studies: Faculty Publications

Urban refugees frequently fall outside of the scope of humanitarian assistance programs. Despite a growing body of research describing the experiences of urban refugees in low- and middle-income countries (LMICs) of first asylum, little is known about generational differences in perceived support in these contexts. This phenomenological study used in-depth, semi-structured interviews and small group discussions to identify sources and meanings of support among older adult (50+; n= 23) and younger adult (18–30; n= 11) Congolese refugees in Dar es Salaam, Tanzania. Family and fictive kin emerged as central sources of support across age groups. However, instrumental support was sought …

Neuropsychological Aspects Of Aging: Implications For Assessment & Intervention, Bruce Vermeer

Faculty Work Comprehensive List

No abstract provided.

Advancing Research On Psychological Stress And Aging With The Health And Retirement Study: Looking Back To Launch The Field Forward, Alexandra D. Crosswell, Madhuvanthi Suresh, Eli Puterman, Tara Gruenewald, Jinkook Lee, Elissa S. Epel

Psychology Faculty Articles and Research

Objectives

The Health and Retirement Study (HRS) was designed as an interdisciplinary study with a strong focus on health, retirement, and socioeconomic environment, to study their dynamic relationships over time in a sample of mid-life adults. The study includes validated self-report measures and individual items that capture the experiences of stressful events (stressor exposures) and subjective assessments of stress (perceived stress) within specific life domains.

Methods

This paper reviews and catalogs the peer-reviewed publications that have used the HRS to examine associations between psychological stress measures and psychological, physical health, and economic outcomes.

Results

We describe the research to date …