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Estrogen And Hippocampal Plasticity In Rodent Models, Michael R. Foy, Michel Baudry, Roberta Diaz Brinton, Richard F. Thompson
Estrogen And Hippocampal Plasticity In Rodent Models, Michael R. Foy, Michel Baudry, Roberta Diaz Brinton, Richard F. Thompson
Psychological Science Faculty Works
Accumulating evidence indicates that ovarian hormones regulate a wide variety of non-reproductive functions in the central nervous system by interacting with several molecular and cellular processes. A growing animal literature using both adult and aged rodent models indicates that 17β-estradiol, the most potent of the biologically relevant estrogens, facilitates some forms of learning and memory, in particular those that involve hippocampal-dependent tasks. A recently developed triple-transgenic mouse (3xTg-AD) has been widely used as an animal model of Alzheimer's disease, as this mouse exhibits an age-related and progressive neuropathological phenotype that includes both plaque and tangle pathology mainly restricted to hippocampus, …
The Effects Of Combining Reduced Luminance And Increased Blur On Older Driver Speed And Visual Acuity, Nathan Klein
The Effects Of Combining Reduced Luminance And Increased Blur On Older Driver Speed And Visual Acuity, Nathan Klein
All Theses
Drivers may be at more risk to themselves and other roadway users when vision is blurred or when luminance levels are reduced. Past research has investigated these visual conditions separately, finding that each degrades acuity without severely impairing steering ability. However, it is unknown how reduced luminance in combination with increased blur will affect driving performance. This study sought to quantify this combined effect on older adults' comfortable driving speed and visual acuity by testing 10 participants in a driving simulator. The majority of the luminance and blur conditions are comparable to those the driving population may realistically encounter. Participants …
Employing Strategy In Measures Of Executive Functioning, Amanda A. Yocum
Employing Strategy In Measures Of Executive Functioning, Amanda A. Yocum
ETD Archive
Although various dementia-related executive deficits have been identified, the functional state of the frontal lobe during healthy aging remains unclear (Raz et al., 2005). The proposed study examines the use of strategy in measures of executive functioning in younger and older adults. Specifically, the strategy types of a nonverbal fluency task are shown to differentially correlate with the actual output generated by participants. The strategies employed here are compared between the two age groups, illustrating that older adults use the best strategy significantly less than younger adults, even when controlling for output differences, which may support the frontal lobe hypothesis …
Attitudes Towards One’S Aging Among Single, Professional, Highly Educated, Baby Boom Women: “I Don’T Know Who I Am, But I Am Not A Crazy Old Maid!”, Tatyana Shepel
Antioch University Full-Text Dissertations & Theses
Age is a value-laden cultural construct as it conveys social attitudes toward aging. This qualitative research, using a grounded theory approach and critical feminist gerontology as a theoretical framework, makes visible the experience of growing older and the renegotiation of self-identity among the ten single, professional, highly educated women ages 47-59 who resided in the Pacific Northwest and lets their voices be heard. In this study ten in-depth interviews and one focus group provided narrative data that captured women’s experiences of aging and uncovered common themes. The explored phenomenon of aging is experienced in the various socio-cultural contexts and conditions …