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Behavioral Economic Demand: Investigation Of Sex Differences In Four Core Genotype Model Of Oral Oxycodone Self-Administration, Michelle Elsmore, David Jentsch, Joshua Peck, Anushree Karkhanis

Undergraduate Honors Theses

Opioid misuse has been identified to be related to problematic release of dopamine in the brain that is otherwise satiated by other alternative rewards. As mediated by patterns of positive and negative reinforcement, prolonged opioid use may transition into misuse and development of opioid use disorder. In human populations, men and women differ in their acquisition of drug use and escalation to drug misuse. Women quickly surpass their male counterparts in their transition from use to misuse in what is coined the telescoping effect. In this four core genotype model of oral oxycodone self administration, males were hypothesized to consume …

Variation In Sign-Tracking And Goal-Tracking Behaviors In A Genetically Diverse Inbred Panel Of Mice, Emily A. Schoenblum

Undergraduate Honors Theses

No abstract provided.

Race In The Relationship Quality Of Sexual Minority People Of Color: A Meta-Analytic Review, Olivia M. Lawrence

Undergraduate Honors Theses

No abstract provided.

Effect Of Motivational Music On Peak Knee Torque, Perceived Exertion, And Enjoyment In College-Aged Individuals, Arianna Cole

Undergraduate Honors Theses

There is a general consensus in previous and current literature that the incorporation of music in exercise has the potential to benefit performance (Karageorghis 2020; Terry et al. 2019). Research on the potential benefits of music in rehabilitative exercise has become more prevalent but has mainly focused on music and the rehabilitation of neurological conditions such as Parkinson's disease or stroke (Craig et al. 2015; De Bartolo et al. 2020; Grau-Sánchez et al. 2022; Katlen da Silva et al. 2021; Särkämö 2018). Research in a more general rehabilitative setting has not been explored as widely and this is the aim …

The Role Of Culture On Psychological Intimate Partner Violence Victimization Among Latinx Males, Saúl A. Padilla

Undergraduate Honors Theses

In this study, I investigated the individual and additive effects of both acculturation and enculturation on experiencing psychological intimate partner violence (IPV) victimization within low-income Latinx males. I hypothesized that there would be a significant positive association between acculturation and psychological IPV victimization, a significant negative association between enculturation and psychological IPV victimization, and a significant negative association between the additive effects of acculturation and enculturation on psychological IPV victimization. To accomplish these aims, this study conducted a secondary analysis of the Future of Families and Child Wellbeing study (FFCWS) data, which assessed low-income mothers and fathers that had just …

The Examination Of Discrimination And Social Bias Toward Interracial Relationships, Tarah Midy

Graduate Dissertations and Theses

Although rates of approval toward interracial couples are increasing (Carroll, 2007), interracial couples report facing prejudice and discrimination including disapproval and ostracism from family, friends, and the general public (Carbone-Lopez, 2013; Martin, Campbell, Ueno, Fincham, 2013; Potter & Thomas, 2012; Troy, Lewis-Smith, Laurenceau, 2006). However, there is growing evidence as acceptance rates and challenges faced by couples vary (Pew Research Center, 2012, Golebiowska, 2007), that experiences are different for couples depending on the racial group and gender of both partners involved.

To better understand the experience of different interracial couples, I conducted two studies to examine the particular stressors they …

Association Between The Magnitude Of The Immune Response And Recurrent Major Depression Disorder In Humans And Depression-Like Behavior In Animals, Anastacia Kudinova

Graduate Dissertations and Theses

There is a growing body of evidence supporting the association between inflammation and major depressive disorder (MDD). One plausible mechanism for this association is sensitization of the immune response, possibly due to prior exposure to stressors. To investigate the validity of this hypothesis, a series of three complimentary cross-species studies was conducted. Study 1 examined the associations between circulating levels of inflammatory markers and in vitro immune reactivity with women’s history of recurrent MDD (rMDD) and their current symptoms of anhedonia. The potential moderating role of women’s history of childhood abuse was also examined. Study 2 and 3 focused on …

Investigating The Effects And Mechanisms Of A Brief Savoring-Based Intervention In Partnered Individuals, Binghuang A. Wang

Graduate Dissertations and Theses

Due to numerous barriers to mental health care access, there exists an extensive need for brief cost-effective interventions for couples. Savoring, which invites individuals to prolong and extend the positive aspect of their experiences, is a promising intervention candidate. Research on savoring has established savoring-based interventions to be efficacious at producing positive intra and interpersonal outcomes. The current investigation expands upon existing savoring research by examining the effects of savoring on an adult population in committed romantic relationships. We expect savoring to be better than control at improving intra and interpersonal outcomes. Furthermore, we aim to investigate intrapersonal factors as …

Intra- And Inter-Personal Predictors Of Posttraumatic Stress Disorder And Sexual Risk-Taking Behaviors, Seigie L. Kennedy

Graduate Dissertations and Theses

Sexual risk-taking, while common in college culture, can increase the risk of sexual victimization. Nearly 20% of college women have been sexually assaulted (Krebs et al., 2009). Moreover, Posttraumatic Stress Disorder (PTSD) has been associated with sexual risk-taking (Johnson & Johnson, 2013). Self-esteem and social support are known to be related to PTSD and sexual risk-taking (Gullette & Lyons, 2006; Johnson & Johnson, 2013). This study aims to examine sexual victimization history, self-esteem, and social support as relative predictors of PTSD and sexual risk-taking using a sample of 229 female undergraduates. Results suggest that enhancing self-esteem, as opposed to bolstering …

Heritable Variation In Reward Sensitivity And Impulsive Cction And Choice In A Genetically Diverse Inbred Mouse Panel, Lauren S. Bailey

Graduate Dissertations and Theses

Research in animal models and human subjects points towards reward sensitivity and impulsivity as being characteristics that predict greater positive subjective responses to stimulant drugs. The Collaborative Cross (CC) recombinant inbred mouse strains and their inbred founders are a powerful genetic reference panel that has potential as a tool for revealing genetic correlations. The CC/DO founder strains were used to examine the heritability of reward sensitivity and impulsivity traits. Founder strains were tested for activity in an open field, reward sensitivity, and reversal learning (impulsive action) or delay discounting (impulsive choice). Significant heritability for anticipatory responding within the reversal task, …

Effects Of Chemogenetic Inhibition Of Dopamine Transporter- Or A2a-Expressing Neurons On Spontaneous Activity And Motivation To Consume A Palatable Food Reward, James D. Wherry

Graduate Dissertations and Theses

Dopamine (DA) transmission in the striatum influences the motivated pursuit of rewarding stimuli. Pharmacological and opto- and chemo-genetic studies have suggested that the release of DA onto D2+/A2A+-expressing striatopallidal neurons, plays a role in this process. To determine the potentially dissociable roles of DA-releasing ventral midbrain and striatopallidal neurons on motivational processes, we employed double transgenic mice that expressed inhibitory DREADDs—designer receptors that are activated only by otherwise inert ligands—only in dopamine transporter (DAT) or A2A adenosine receptor (A2A) expressing neurons, allowing us to transiently inhibit either DA-releasing neurons (DATcre/DREADD) or striatopallidal neurons (A2Acre/DREADD) during various tests. In the first …

Causes And Predictors Of Thematic Intrusion On Human Similarity Judgments, Garrett R. Honke

Graduate Dissertations and Theses

Most theoretical accounts of psychological similarity maintain that similarity judgments are based on shared features (and shared relations among those features, e.g., the commonalities between spatula and ladle). Accounts rarely include associations between targets of comparison (e.g., the association between egg and spatula) as a contributor to similarity judgments. This position is taken despite the fact that people will often choose associates over things with shared features and relations in similarity judgment tasks. So-called dual-process models - where thematic integration and feature (and relation) based comparison are component processes of perceived human similarity - have been proposed to handle this …

Thiamine Deficiency And Alcohol Exposure Both Lead To An Impulsive Phenotype, Robin J. Zimmer

Graduate Dissertations and Theses

The detrimental effects of alcohol consumption, including impulsivity, cognitive inflexibility, and neuropathology, are due to a confluence of factors that often occur in addition to alcoholism. We examined the effects of chronic alcohol exposure and thiamine deficiency (or supplementation) in isolation, as well as in concert, to further our understanding of the independent effects of each treatment and how they interact. Our results demonstrated that both chronic alcohol exposure and moderate thiamine deficiency induce an impulsive phenotype. Importantly, the increased impulsivity induced by thiamine deficiency was protracted as compared to that exhibited after chronic alcohol alone. Additionally, differential pathology was …

Mind-Craft: Exploring The Relation Between "Digital" Visual Experience And Orientation In Visual Contour Perception, Daniel Hipp

Graduate Dissertations and Theses

Visual perception depends fundamentally on statistical regularities in the environment to make sense of the world. One such regularity is the orientation anisotropy typical of natural scenes; most natural scenes contain slightly more horizontal and vertical information than oblique information. This property is likely a primary cause of the “oblique effect” in visual perception, in which subjects experience greater perceptual fluently with horizontally and vertically oriented content than oblique. However, recent changes in the visual environment, including the “carpentered” content in urban scenes and the framed, caricatured content in digital screen media presentations, may have altered the level of orientation …

Visual Attention To Emotional Stimuli In Individuals High On Psychopathic Traits: Evidence From Eye Tracking, Donna M. Crossman

Graduate Dissertations and Theses

Researchers have described psychopaths as callous, cold-hearted individuals who show reduced empathic response to their victims. It is suggested that the inability to identify negative emotions, specifically fear, in individuals is what allows psychopaths to offend/take advantage of other people as they do not recognize the fear in victims that may otherwise deter victimization. This is the first study to examine how non-incarcerated individuals high on psychopathic personality traits process emotions. Additionally, eye-tracking technology was used to provide a more fine-grained assessment of attention. In contrast to hypotheses, the high psychopathic group did not differ from the low psychopathic or …

Hypnosis, Hypnotizability, Memory And Involvement In Films, Reed Maxwell

Graduate Dissertations and Theses

Researchers have reported increased involvement in reading (Baum and Lynn, 1981) and music-listening (Snodgrass and Lynn, 1989) tasks during hypnosis. We predicted a similar effect for film viewing of greater absorption and involvement in an emotional (The Champ) versus a non-emotional ( Scenes of Toronto) film clip. We also examined the effects of hypnosis and film valence on memory and state depersonalization. Our study is the first to use state dissociation to index response to hypnosis. We tested 121 participants who completed measures of absorption and trait dissociation and the Harvard Group Scale of Hypnotic Susceptibility and …

Cognitive Modeling Analysis Of Decision-Making Processes In Young Adults At-Risk And Not At-Risk For Alcohol Dependence, Lori Anne Wagner

Graduate Dissertations and Theses

This study used the Valence-Expectancy Learning model, a mathematical cognitive model, to dissect young adult performance on the Iowa Gambling Task (IGT). Drinking behavior and monetary incentive were examined as predictors of performance on the IGT. No differences were found among groups when data were analyzed using traditional behavioral analyses. However, when the Expectancy-Valence Learning model was applied to the data, differences between groups were found related to attention and choice consistency. Importantly, the cognitive model was not a good fit for fifty-seven percent of the data, meaning that it did not succeed in explaining how the participants' choices were …

The Effects Of Post-Training Strychnine Treatment Of The Long Term Retention Of Discrimination Training By Mice, Michael John Brennan

Graduate Dissertations and Theses

An attempt was made to determine the effects of post-training strychnine treatment on the retention of specific memory attributes over extended temporal intervals. Heterogeneous strain (Binghamton HET) mice were given two training trials (1 trial per day) on a discrimination problem for which there was two relevant redundant stimulus cues, a brightness cue and a spatial-sequence cue. Immediately after the second training trial, mice were administered intraperitoneal injections of either strychnine sulphate (1 . 0 mg/kg) or physiological saline. After retention intervals of either 1, 3, or 27 day s, mice were tested under either complete cue reversal (both training …

Verbal Short-Term Storage And Analysis-By-Synthesis Of Speech : Evidence For Common Mechanisms, James W. Aldridge

Graduate Dissertations and Theses

Since the late 1950s a great deal of research has been directed toward elucidating the process(es) by which humans retain verbal material for short intervals of time. The purpose of the present paper will be to explore the extent to which such memorial processes can be identified with processes which may be employed in information processing tasks in general, and speech perception and/or production in particular.

Attentional Processes In Auditory Discriminations, William A. Ahroon

Graduate Dissertations and Theses

A set of experiments is described which assessed the ability of human observers to monitor two earphone channels in order to perform one or two independent frequency discriminations. Performance (d′) was significantly poorer with dichotic stimulus presentation than in monaural control conditions. A detailed analysis of the data suggested that two factors were involved in the dichotic performance deficits. The first factor was a limited ability of the observers to perceptually separate the different stimuli presented to the two earphone channels. Under certain stimulus conditions, the channel-separation factor was significant enough to produce a low performance ceiling which overshadowed additional …

The Effects Of Environmental Switchovers Between Enrichment And Impoverishment On Brain And Behavior In Mice, Judith K. Ahroon

Graduate Dissertations and Theses

Rearing rodents or primates in environments that are comparatively enriched or impoverished results in often impressive physiological and anatomical changes after a certain period of exposure. However, the anatomical and biochemical characteristics that respond to environmental experience (Bennett, Diamond, Krech, & Rosenzweig, 1964; Greenough & Volkmar, 1973; Walsh, Budtz-Olsen, Penny, & Cummins, 1969) have been subjected to a more sophisticated level of analysis than have the less consistent changes in behavioral tendencies. The specific nature of environmentally induced modifications in behavioral tendencies must be better understood, if substantive predictions about brain-behavior relationships can be made. Furthermore, the long-term effects of …

Neural Correlates Of Cardiac Orienting Response Habituation, Judith Craig Sanwald

Graduate Dissertations and Theses

This study represents an attempt to determine some of the neural correlates of habituation to repetitive auditory stimulation, and to relate those correlates to the existing theories concerning habituation mechanisms. As the following literature review will reveal, a well controlled correlational study dealing with habituation to auditory stimulation is needed.