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For Dignity Or Money: Feminists On The Commodification Of Women’S Reproductive Labour, Carolyn Mcleod

Philosophy Publications

No abstract provided.

Structural Mri Discriminates Individuals With Mild Cognitive Impairment From Age-Matched Controls: A Combined Neuropsychological And Voxel Based Morphometry Study, Mehul A. Trivedi, Allison K. Wichmann, Britta M. Torgerson, Michael A. Ward, Taylor W. Schmitz, Michele L. Ries, Rebecca L. Koscik, Sanjay Asthana, Sterling C. Johnson

Brain and Mind Institute Researchers' Publications

Background: Several previous studies have reported that amnestic mild cognitive impairment (aMCI), a significant risk factor for Alzheimer's disease (AD), is associated with greater atrophy in the medial temporal lobe (MTL) and posterior cingulate gyrus (PCG). Method: In the present study, we examined the cross-sectional accuracy (i.e., the sensitivity and specificity) of voxel-based morphometry (VBM) in discriminating individuals with MCI (n = 15) from healthy age-matched controls (n = 15). In addition, we also sought to determine whether baseline GM volume predicted aMCI patients that converted to AD from those that did not approximately 2 years after the baseline visit. …

Self-Appraisal Decisions Evoke Dissociated Dorsal-Ventral Ampfc Networks, Taylor W. Schmitz, Sterling C. Johnson

Brain and Mind Institute Researchers' Publications

The anterior medial prefrontal cortex (aMPFC) is consistently active during personally salient decisions, yet the differential contributory processes of this region along the dorsal-ventral axis are less understood. Using a self-appraisal decision-making task and functional magnetic resonance imaging, we demonstrated task-dependent connectivity of ventral aMPFC with amygdala, insula, and nucleus accumbens, and dorsal aMPFC connectivity with dorsolateral PFC and bilateral hippocampus. These aMPFC networks appear to subserve distinct contributory processes inherent to self-appraisal decisions, specifically a dorsally mediated cognitive and a ventrally mediated affective/self-relevance network. © 2005 Elsevier Inc. All rights reserved.

Task-Dependent Posterior Cingulate Activation In Mild Cognitive Impairment, Michele L. Ries, Taylor W. Schmitz, Tisha N. Kawahara, Britta M. Torgerson, Mehul A. Trivedi, Sterling C. Johnson

Brain and Mind Institute Researchers' Publications

Neuroimaging research has demonstrated that the posterior cingulate cortex (PCC) is functionally compromised in individuals diagnosed with amnestic mild cognitive impairment (MCI), a major risk factor for the development of Alzheimer's disease (AD). In functional MRI studies with healthy participants, this same region is active during self-appraisal (requiring retrieval of semantic knowledge about the self) as well as episodic recognition of previously learned information. Administering both types of tasks to people with MCI may reveal important information on the role of the PCC in recollection. This study investigated fMRI activation in the PCC in individuals with MCI and matched controls …

Reduced Hippocampal Activation During Episodic Encoding In Middle-Aged Individuals At Genetic Risk Of Alzheimer's Disease: A Cross-Sectional Study, Mehul A. Trivedi, Taylor W. Schmitz, Michele L. Ries, Britta M. Torgerson, Mark A. Sager, Bruce P. Hermann, Sanjay Asthana, Sterling C. Johnson

Brain and Mind Institute Researchers' Publications

Background: The presence of the apolipoprotein E (APOE) ε4 allele is a major risk factor for the development of Alzheimer's disease (AD), and has been associated with metabolic brain changes several years before the onset of typical AD symptoms. Functional MRI (fMRI) is a brain imaging technique that has been used to demonstrate hippocampal activation during measurement of episodic encoding, but the effect of the ε4 allelle on hippocampal activation has not been firmly established. Methods: The present study examined the effects of APOE genotype on brain activation patterns in the media[ temporal lobe (MTL) during an episodic encoding task …

The Role Of Radiation Therapy On Medically Inoperable Clinically Localized Non-Small Cell Lung Patients: London Regional Cancer Program (Lrcp) Clinical Experience, Michael Lee, Edward Yu, Robert Ash, Patricia Tai, Larry Stitt, George Rodrigues, Rashid Dar, Mark Vincent, Richard Inculet, Richard Malthaner

Oncology Presentations

Lung cancer is the most frequent cause of cancer death in both men and women in North America. In 2006, an estimated 22,700 Canadians will be diagnosed with lung cancer and 19,300 will die of it (Canadian Cancer Statistics 2006).

Approximately 15-20% of NSCLC patients present with early or localized disease.

Surgical resection of T1-2N0 NSCLC remains the treatment of choice for this population, and results in a 5-year survival rate of 50-70%.

Patients deemed medically inoperable have been treated with non-surgical therapies, such as radiation therapy(RT), while some patients have simply been observed without any tumor therapy because of …

Perspectives Of Women With Dementia Receiving Care From Their Adult Daughters, Catherine Ward-Griffin, Nancy Bol, Abram Oudshoorn

Nursing Publications

(Article in English)

Le vécu inhérent à la prestation des soins aux personnes atteintes d’Alzheimer est relativement bien documenté.Toutefois,peu de recherches ont été réalisées du point de vue de la personne souffrant de démence.L’objectif de cette étude, qui s’inscrit dans une recherche qualitative sur les relations mères-filles en contexte de démence,notamment sur le processus de soins,est de recueillir les perceptions et les expériences des mères soignées par leur fille adulte.Guidés par des perspectives féministes et axées sur les étapes de vie,les chercheurs ont mené des entrevues en profondeur et semi-structurées auprès d’un échantillonnage diversifié de 10 femmes non-institutionnalisées et atteintes …

Indigenous Suicide In New Zealand, Annette L. Beautrais, David M. Fergusson

Aboriginal Policy Research Consortium International (APRCi)

This article describes patterns of suicide and attempted suicide among the indigenous (Ma ̄ori) population of New Zealand using official data from the New Zealand Health Information Service (NZHIS). The majority of Ma ̄ori suicides (75%) occurr in young people aged <35 years. Rates of suicide are higher among Ma ̄ori males and females aged <25 than in their non-Ma ̄ori peers. Rates of hospitalization for attempted suicides are higher amongst Ma ̄ori males aged 15–24, compared to non-Ma ̄ori. In contrast, suicide is virtually unknown amongst older Ma ̄ori (60 years). This article reviews explanations for the observed rates of suicide in Ma ̄ori, and examines approaches to effective intervention to reduce rates of suicide in young Ma ̄ori.

Characteristics Of Aboriginal Injecting Drug Users In Sydney, Australia: Prison History, Hepatitis C Status And Drug Treatment Experiences, Carolyn Day, Joanne Ross, Kate Dolan

Aboriginal Policy Research Consortium International (APRCi)

Australian Aboriginals are overrepresented in prisons and tend to be overrepresented in studies of injecting drug users (IDU). The aim of this study was to examine differences between Aboriginal and non-Aboriginal IDUs in terms of gender, prison history and hepatitis C status and testing. Secondary analyses were conducted on data from three cross-sectional studies of IDUs. These studies employed similar methodologies, with recruitment being through needle and syringe programs, methadone clinics, snowballing and street intercepts. All studies were coordinated through the National Drug and Alcohol Research Centre. Aboriginal people were overrepresented in all studies, were more likely to have been …

Mere And Partial Means: The Full Range Of The Objectification Of Women, Carolyn Mcleod

Philosophy Publications

No abstract provided.

Diagnostic And Therapeutic Procedures Among Australian Hospital Patients Identified As Indigenous, Joan Cunningham

Aboriginal Policy Research Consortium International (APRCi)

Objectives: To determine whether hospital patients identified as Indigenous are less likely than other inpatients to have a principal procedure recorded, and the extent to which any disparity in procedure use can be explained by differences in patient, episode and hospital characteristics. Design: Retrospective analysis of routinely collected administrative data from the National Hospital Morbidity Database (NHMD). Setting: Australian public and private hospitals. Patients: All patients included in the NHMD whose episode type was recorded as acute and whose separation occurred between 1 July 1997 and 30 June 1998. Patients admitted for routine dialysis treatment were excluded. Main outcome measure: …

Substance Abuse Among Urban Aboriginals, Kahá:Wi J. Jacobs, Kathryn J. Gill

Aboriginal Policy Research Consortium International (APRCi)

This paper reports findings of a study of mental health among urban Aboriginal peoples. Both qualitative and quantitative techniques were used to explore the relationship between substance abuse and physical/sexual abuse in a sample of Aboriginal peoples living in an urban community. Open-ended interviews were conducted in a sample of 30 Aboriginals that included Aboriginal social service providers (from health, legal and family services). Forty percent of the sample had been abused and many experienced social, psychological and emotional prob- lems associated with abusive experiences. Content analysis of the interviews revealed common themes in violence discourse including loss of identity …

Relational Autonomy, Self-Trust, And Health Care For Patients Who Are Oppressed, Carolyn Mcleod, Susan Sherwin

Philosophy Publications

No abstract provided.

Self-Trust And Reproductive Autonomy, Carolyn Mcleod

Philosophy Publications

In this thesis. I give a theory of the nature of self-trust and an explanation of its role in autonomous decision-making. We tend to think of trust as essentially interpersonal which casts doubt on the coherence of the concept of self-trust. Drawing on patients' experiences in reproductive medicine. I argue that self-trust is a meaningful as well as a useful concept. I provide autobiographical sketches of a number of women's experiences. supplemented by my own observations made while doing a clinical practicum in reproductive medicine, to illustrate that what many women feel toward themselves in a variety of reproductive health …

Trudy Govier’S Dilemmas Of Trust, Carolyn Mcleod, S. Burns

Philosophy Publications

No abstract provided.

Uwomj Volume 68, Number 1, Winter 1999, Western University

University of Western Ontario Medical Journal

Schulich School of Medicine & Dentistry

Selecting Subjects For Participation In Clinical Research: An Empirical Inquiry And Ethical Analysis, Charles Weijer

Philosophy Publications

Procedures for the selection of subjects for participation in randomized clinical trials--usually formalized as eligibility criteria in the study protocol--have both scientific and ethical implications. In this thesis, I undertake an examination of eligibility criteria at three stages in the genesis and dissemination of medical knowledge: clinical trial protocol, interpretation by investigators, and reporting of study results.

In the first chapter, ethical issues in subject selection are reviewed and the main study questions are presented. In the second chapter, the results of an examination of eligibility criteria in two sets of clinical trials, one sponsored by the NSABP, the other …

Uwomj Volume 66, No 1, Winter 1996-97, Western University

University of Western Ontario Medical Journal

An interdisciplinary medical science publication, established in 1930.

Characterizing The Population In Clinical Trials: Barriers, Comparability, And Implications For Review, Charles Weijer

Philosophy Publications

The definition of the study population for a clinical trial via the criteria for trial eligibility has implications for the validity of the study and its applicability to clinical practice. Though issues of equity regarding the selection of subjects for research have long been a concern of ethicists, issues regarding the impact of subject selection on a trial's generalizability have only recently attracted ethical scrutiny. After a review of the history of the ethics of subject selection, I focus on three empirical questions regarding the generalizability of clinical trials. (1) What proportion of diseased populations are studied in clinical trials? …

Uwomj Volume 65, No 1, Winter 1995-96, Western University

University of Western Ontario Medical Journal

An interdisciplinary medical science publication, established in 1930.

Uwomj Volume 62, Number 2, Spring 1993, Western University

University of Western Ontario Medical Journal

Schulich School of Medicine & Dentistry

Uwomj Volume 63, Number 1, Fall 1993, Western University

University of Western Ontario Medical Journal

Schulich School of Medicine & Dentistry

Uwomj Volume 57, No.1, Western University

University of Western Ontario Medical Journal

The title of our cover "Give all little children their chance" in Creole

Schulich School of Medicine & Dentistry

Uwomj Volume 53, Number 1, November 1983, Western University

University of Western Ontario Medical Journal

Schulich School of Medicine & Dentistry

Uwomj Volume 50, Number 1, April 1980, Western University

University of Western Ontario Medical Journal

Schulich School of Medicine & Dentistry

Uwomj Volume 29, Number 1, January 1959, Western University

University of Western Ontario Medical Journal

Schulich School of Medicine & Dentistry