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Participant Responses To Retrospective Surveys Of Child Maltreatment: Does Mode Of Assessment Matter? , David Dilillo, Sarah Degue, Amanda Kras, Andrea R. Di Loreto-Colgan, Cindy Nash
Participant Responses To Retrospective Surveys Of Child Maltreatment: Does Mode Of Assessment Matter? , David Dilillo, Sarah Degue, Amanda Kras, Andrea R. Di Loreto-Colgan, Cindy Nash
Department of Psychology: Faculty Publications
This study examines the impact that different methods of assessing child maltreatment history may have on adult participants. A total of 334 female undergraduate students were randomly assigned to complete a retrospective measure of child sexual and physical abuse in one of three conditions: paper-and-pencil questionnaire, face-to-face interview, or computer-administered survey. Disclosure rates of abuse, psychological distress and mood change, preferences for assessment format, and perceptions of confi dentiality were examined across the three assessment formats. Although disclosure did not vary by condition, participants with a history of abuse reported more distress and mood change than did nonvictims, particularly in …
Effect Of Nicotine On Negative Affect Among More Impulsive Smokers, Neal Doran, Dennis E. Mcchargue, Bonnie Springs, Joe Vanderveen, Jessica Werth Cook, Malia Richmond
Effect Of Nicotine On Negative Affect Among More Impulsive Smokers, Neal Doran, Dennis E. Mcchargue, Bonnie Springs, Joe Vanderveen, Jessica Werth Cook, Malia Richmond
Department of Psychology: Faculty Publications
In the present study, the authors tested the hypothesis that nicotine would provide greater relief from negative affect for more impulsive smokers than for less impulsive smokers. Euthymic adult smokers (N = 70) participated in 2 laboratory sessions, during which they underwent a negative mood induction (music x autobiographical memory), then smoked either a nicotinized or de-nicotinized cigarette. Mixed-effects regression yielded a significant Impulsivity x Condition (nicotinized vs. de-nicotinized) x Time interaction. Simple effects analyses showed that heightened impulsivity predicted greater negative affect relief after smoking a nicotinized cigarette but not after smoking a de-nicotinized cigarette. These data suggest …
Adolescent Perceptions Of Appropriate Parental Reactions In Moral And Conventional Social Domains, Laura M. Padilla-Walker, Gustavo Carlo
Adolescent Perceptions Of Appropriate Parental Reactions In Moral And Conventional Social Domains, Laura M. Padilla-Walker, Gustavo Carlo
Department of Psychology: Faculty Publications
Research suggests that adolescents’ ratings of the appropriateness of parental reactions are influenced by several constructs, including adolescents’ perceptions of the type of parental reaction, the emotions felt by the adolescent and parental intentions. However, little is known regarding how these constructs are differentially predictive of appropriateness in different socialization contexts. One hundred and twenty-two adolescents (mean age = 16.87 years) answered questions regarding past situations in antisocial and prosocial contexts, and in moral and conventional domains. Different parental reactions were reported across moral and conventional domains. In addition, the appropriateness of parental responses varied across domain. Namely, in antisocial …
Elevated Positive Mood: A Mixed Blessing For Abstinence, Neal Doran, Bonnie Spring, Belinda Borrelli, Dennis E. Mcchargue, Brian Hitsman, Raymond Niaura, Donald Hedecker
Elevated Positive Mood: A Mixed Blessing For Abstinence, Neal Doran, Bonnie Spring, Belinda Borrelli, Dennis E. Mcchargue, Brian Hitsman, Raymond Niaura, Donald Hedecker
Department of Psychology: Faculty Publications
The present study, a secondary analysis of published data (B. Hitsman et al., 1999), assessed (a) the influence of initial positive mood (PM) on smoking cessation and (b) whether smokers low in PM benefited from fluoxetine versus placebo for cessation. Euthymic adult smokers (N = 103) received 10 weeks of cessation treatment. Analyses showed a Time x PM interaction, indicating that higher baseline PM predicted decreased abstinence during treatment but increased abstinence afterward, mediated by time to dropout. Dichotomous initial PM interacted with drug, suggesting a benefit of fluoxetine for low-PM smokers. Results indicate that lower pretreatment PM may …
Mean Length Of Utterance In Children With Specific Language Impairment And In Younger Control Children Shows Concurrent Validity And Stable And Parallel Growth Trajectories, Mabel L. Rice, Sean M. Redmond, Lesa Hoffman
Mean Length Of Utterance In Children With Specific Language Impairment And In Younger Control Children Shows Concurrent Validity And Stable And Parallel Growth Trajectories, Mabel L. Rice, Sean M. Redmond, Lesa Hoffman
Department of Psychology: Faculty Publications
Purpose: Although mean length of utterance (MLU) is a useful benchmark in studies of children with specific language impairment (SLI), some empirical and interpretive issues are unresolved. The authors report on 2 studies examining, respectively, the concurrent validity and temporal stability of MLU equivalency between children with SLI and typically developing children. Method: Study 1 used 124 archival conversational samples consisting of 39 children with SLI (age 5;0 [years;months]), 40 MLU-equivalent typically developing children (age 3;0), and 45 age-equivalent controls. Concurrent validity of MLU matches was examined by considering the correspondence between MLU and developmental sentence scoring (DSS), …
Agricultural Pesticide Use And Risk Of T(14;18)-Defined Subtypes Of Non-Hodgkin Lymphoma, Brian C.-H. Chiu, Bhavana J. Dave, Aaron Blair, Susan M. Gapstur, Shelia Hoar Zahm, Dennis D. Weisenburger
Agricultural Pesticide Use And Risk Of T(14;18)-Defined Subtypes Of Non-Hodgkin Lymphoma, Brian C.-H. Chiu, Bhavana J. Dave, Aaron Blair, Susan M. Gapstur, Shelia Hoar Zahm, Dennis D. Weisenburger
Public Health Resources
Pesticides have been specifically associated with the t(14;18)(q32;q21) chromosomal translocation. To investigate whether the association between pesticides and risk of non-Hodgkin lymphoma (NHL) differs for molecular subtypes of NHL defined by t(14; 18) status, we obtained 175 tumor blocks from case subjects in a population-based case-control study conducted in Nebraska between 1983 and 1986. The t(14;18) was determined by interphase fluorescence in situ hybridization in 172 of 175 tumor blocks. We compared exposures to insecticides, herbicides, fungicides, and fumigants in 65 t(14;18)-positive and 107 t(14;18)-negative case subjects with those among 1432 control subjects. Multivariate polytomous logistic regression was used to …
Using Initiative To Achieve Autonomy: A Model For Advanced Practice In Medical Nutrition Therapy, Annalynn Skipper, Nancy M. Lewis
Using Initiative To Achieve Autonomy: A Model For Advanced Practice In Medical Nutrition Therapy, Annalynn Skipper, Nancy M. Lewis
Department of Nutrition and Health Sciences: Faculty Publications
The purpose of this research was to generate a model of advanced medical nutrition therapy (MNT) practice based on descriptions of their clinical activities provided by advanced- level MNT practitioners. A qualitative approach using grounded theory methodology was employed. The model of advanced MNT practice was based on interviews with 21 credentialed advanced practice registered dietitians from across the United States and Canada. Verbatim transcripts of the interviews were coded for aggregation into themes and subthemes. The resulting model included a single overarching theme: using initiative to achieve autonomy. The five subthemes are aptitude, attitude, expertise, context, and approach. The …
Validity And Reliability Of A Quantitative Food Frequency Questionnaire Measuring N-3 Fatty Acid Intakes In Cardiac Patients In The Midwest: A Validation Pilot Study, Paula K. Ritter-Gooder, Nancy M. Lewis, Kimberly B. Heidal, Kent M. Eskridge
Validity And Reliability Of A Quantitative Food Frequency Questionnaire Measuring N-3 Fatty Acid Intakes In Cardiac Patients In The Midwest: A Validation Pilot Study, Paula K. Ritter-Gooder, Nancy M. Lewis, Kimberly B. Heidal, Kent M. Eskridge
Department of Nutrition and Health Sciences: Faculty Publications
The purpose of this pilot study was to test the validity and reliability of a quantitative n-3 fatty acid food frequency questionnaire (FFQ) for later use with larger groups of individuals. A convenience sample of heart patients provided dietary data via three 24-hour food recalls and FFQs. Participants were women (n = 17) and men (n = 11), 43 to 77 years of age. The association of mean daily intake of n-3 fatty acids obtained using food recalls and the FFQ was assessed by Pearson correlation. The reliability of the FFQ was assessed using coefficient α. Correlation of n-3 fatty …
Characteristics Of Staff-Patient Interactions On A Behavioral Treatment Unit For Patients With Serious Mental Illness, And The Effects Of A Behavior Management Training Program On Staff Performance, Lindsay S. Schenkel
Department of Psychology: Dissertations, Theses, and Student Research
Despite the existence of effective psychological interventions for people diagnosed with schizophrenia, these continue to be underutilized. This problem is most critical in the case of so called “treatment-refractory” patients, where, paradoxically, effective interventions with among the strongest evidence base in psychiatry exist – namely – inpatient social-learning-based rehabilitation programs. Barriers to implementation and effective maintenance of such programs include a low frequency of staff-patient interactions and a relatively high frequency of non-therapeutic staff behaviors, lack of staff training and background in behavioral treatment, negative attitudes towards behavioral interventions, and tension between professional disciplines. This study examined the nature and …
Early Predictors Of Self-Regulation In Middle Childhood, Rebecca A. Colman, Sam A. Hardy, Myesha Albert, Marcela Raffaelli, Lisa J. Crockett
Early Predictors Of Self-Regulation In Middle Childhood, Rebecca A. Colman, Sam A. Hardy, Myesha Albert, Marcela Raffaelli, Lisa J. Crockett
Department of Psychology: Faculty Publications
The present study examined the contribution of caregiving practices at ages 4–5 (Time 1) to children’s capacity for self regulation at ages 8–9 (Time 2). The multiethnic sample comprised 549 children of National Longitudinal Survey of Youth (NLSY) participants. High levels of maternal warmth and low levels of physically punitive discipline at Time 1 were associated with a greater capacity for self-regulation at Time 2. These associations remained significant once initial levels of self-regulation were taken into account, indicating that the development of self-regulation is open to caregiver infl uence during childhood. Neither child gender nor ethnicity moderated the effects …
Disease Risks Associated With Increasing Feral Swine Numbers And Distribution In The United States, Thomas Hutton, Thomas J. Deliberto, Sheldon Owen, Bruce Morrison
Disease Risks Associated With Increasing Feral Swine Numbers And Distribution In The United States, Thomas Hutton, Thomas J. Deliberto, Sheldon Owen, Bruce Morrison
Michigan Bovine Tuberculosis Bibliography and Database
Feral hogs or “wild boars” come from several sources and include released or escaped domestic swine and the truly wild European boar. When free-roaming in North America, all are included in the term “feral swine,” as are hybrids of the two types. Although morphologically distinct, both the feral swine and European wild swine are recognized as Sus scrofa. The physical damage caused by feral swine has been well documented and includes damage to vehicles, vineyards, tree plantings, archaeological sites, agricultural crops, turf, soils, rare plant communities, and wildlife habitat (Seward et al. 2004). In addition they compete with livestock …
Visualization Of Intracellular Transport Of Vesicular Stomatitis Virus Nucleocapsids In Living Cells, Subash C. Das, Debasis Nayak, You Zhou, Asit K. Pattnaik
Visualization Of Intracellular Transport Of Vesicular Stomatitis Virus Nucleocapsids In Living Cells, Subash C. Das, Debasis Nayak, You Zhou, Asit K. Pattnaik
School of Veterinary and Biomedical Sciences: Faculty Publications
The phosphoprotein (P) of vesicular stomatitis virus (VSV) is a subunit of the viral RNA polymerase. In previous studies, we demonstrated that insertion of 19 amino acids in the hinge region of the protein had no significant effect on P protein function. In the present study, we inserted full-length enhanced green fluorescent protein (eGFP) in frame into the hinge region of P and show that the fusion protein (PeGFP) is functional in viral genome transcription and replication, albeit with reduced activity. A recombinant vesicular stomatitis virus encoding PeGFP in place of the P protein (VSV-PeGFP), which possessed reduced growth kinetics …
Evaluation Of Serum Immunoglobulins Among Individuals Living Near Six Superfund Sites, Dhelia M. Williamson, Mary C. White, Charles Poole, David Kleinbaum, Robert Vogt, Kari North
Evaluation Of Serum Immunoglobulins Among Individuals Living Near Six Superfund Sites, Dhelia M. Williamson, Mary C. White, Charles Poole, David Kleinbaum, Robert Vogt, Kari North
Public Health Resources
Residents living in communities near Superfund sites have expressed concern that releases from these facilities affect their health, including adverse effects on their immune systems. We used data from six cross-sectional studies to evaluate whether people who live near several Superfund sites are more likely to have individual immunoglobulin test results (IgA, IgG, and IgM) below or above the reference range than those who live in comparison areas with no Superfund site. Study participants consisted of target-area residents who lived close to a Superfund site and comparison area residents who were not located near any Superfund or hazardous waste sites. …
Cross-Subtype T-Cell Immune Responses Induced By A Human Immunodeficiency Virus Type 1 Group M Consensus Env Immunogen†0--, Eric A. Weaver, Zhongjing Lu, Zenaido T. Camacho, Fatiha Moukdar, Hua-Xin Liao, Ben-Jiang Ma, Mark Muldoon, James Theiler, Gary J. Nabel, Norman L. Letvin, Bette T. Korber, Beatrice H. Hahn, Barton F. Haynes, Feng Gao
Cross-Subtype T-Cell Immune Responses Induced By A Human Immunodeficiency Virus Type 1 Group M Consensus Env Immunogen†0--, Eric A. Weaver, Zhongjing Lu, Zenaido T. Camacho, Fatiha Moukdar, Hua-Xin Liao, Ben-Jiang Ma, Mark Muldoon, James Theiler, Gary J. Nabel, Norman L. Letvin, Bette T. Korber, Beatrice H. Hahn, Barton F. Haynes, Feng Gao
Nebraska Center for Virology: Faculty Publications
The genetic diversity among globally circulating human immunodeficiency virus type 1 (HIV-1) strains is a serious challenge for HIV-1 vaccine design. We have generated a synthetic groupMconsensus env gene (CON6) for induction of cross-subtype immune responses and report here a comparative study of T-cell responses to this and natural strain env immunogens in a murine model. Three different strains of mice were immunized with CON6 as well as subtype A, B, or C env immunogens, using a DNA prime-recombinant vaccinia virus boost strategy. T-cell epitopes were mapped by gamma interferon enzyme-linked immunospot analysis using five overlapping Env peptide sets from …
Sensitivity Of The Anxiety Disorder Interview Schedule Iv In Detecting Potentially Traumatic Childhood Maltreatment, David Dilillo, Sarah A. Hayes, Debra A. Hope
Sensitivity Of The Anxiety Disorder Interview Schedule Iv In Detecting Potentially Traumatic Childhood Maltreatment, David Dilillo, Sarah A. Hayes, Debra A. Hope
Department of Psychology: Faculty Publications
This study examined the sensitivity of the Anxiety Disorder Interview Schedule IV (ADIS-IV) in detecting potentially traumatic childhood abuse experiences in a sample of 50 consecutive adult anxiety disorder patients. Of 13 patients who reported traumatic childhood maltreatment experiences using a behaviorally specific abuse history questionnaire, seven failed to report these experiences during the ADIS-IV interview (a sensitivity of 46%). Findings suggest that the two omnibus gating questions on the ADIS-IV may be insufficient in capturing exposure to certain traumatic events, as stipulated by Diagnostic and Statistical Manual diagnostic criteria for a diagnosis of post-traumatic stress disorder (PTSD). This potential …
Two Sides Of The Same Coin? The Relations Between Prosocial And Physically Aggressive Behaviors, Meredith Mcginley, Gustavo Carlo
Two Sides Of The Same Coin? The Relations Between Prosocial And Physically Aggressive Behaviors, Meredith Mcginley, Gustavo Carlo
Department of Psychology: Faculty Publications
The direct and indirect relations between six types of prosocial behavior and physical aggression were examined. Data were gathered from 252 college students (M age = 21.67 years; 184 women) who completed measures of sympathy, prosocial behavior, and physical aggression. Structural equation modeling revealed that sympathy fully mediated the relations between compliant prosocial behaviors and physical aggression, and partially mediated the relations between altruism and physical aggression and public prosocial behaviors and physical aggression. The fi ndings suggest that the relations between prosocial behaviors and aggression are complex and that prosocial behavior should not be treated as a unitary construct.
Significance Of Heat-Stable And Heat-Labile Enterotoxins In Porcine Colibacillosis In An Additive Model For Pathogenicity Studies, Weiping Zhang, Emil M. Berberov, Jessica Freeling, D. He, Rodney A. Moxley, David H. Francis
Significance Of Heat-Stable And Heat-Labile Enterotoxins In Porcine Colibacillosis In An Additive Model For Pathogenicity Studies, Weiping Zhang, Emil M. Berberov, Jessica Freeling, D. He, Rodney A. Moxley, David H. Francis
School of Veterinary and Biomedical Sciences: Faculty Publications
Although heat-stable (ST) and heat-labile (LT) enterotoxins produced by enterotoxigenic Escherichia coli (ETEC) have been documented as important factors associated with diarrheal diseases, investigations assessing the contributions of individual enterotoxins to the pathogenesis of E. coli infection have been limited. To address the individual roles of enterotoxins in the diarrheal disease caused by K88-positive ETEC in young pigs, enterotoxin-positive and -negative isogenic E. coli strains were constructed by using pBR322 to clone and express LT and STb. Four strains, K88+ astA, K88+ astA/pBR322, K88+ astA STb+, and K88+ astA LT+, were constructed …
Development Of Luminescent Mycobacterium Avium Subsp. Paratuberculosis For Rapid Screening Of Vaccine Candidates In Mice, Valerie Rosseels, Virginie Roupie, Denise K. Zinniel, Raul G. Barletta, Kris Huygen
Development Of Luminescent Mycobacterium Avium Subsp. Paratuberculosis For Rapid Screening Of Vaccine Candidates In Mice, Valerie Rosseels, Virginie Roupie, Denise K. Zinniel, Raul G. Barletta, Kris Huygen
School of Veterinary and Biomedical Sciences: Faculty Publications
Mycobacterium avium subsp. paratuberculosis is a slowly growing mycobacterial species, requiring 6 to 8 weeks of culture before colonies can be counted visually. Here, we describe the development of luminescent M. avium subsp. paratuberculosis expressing luxAB genes of Vibrio harveyi and its use for vaccine testing in an experimental mouse model, replacing fastidious CFU counting by rapid luminometry.
Mugshot Exposure Effects: Retroactive Interference, Mugshot Commitment, Source Confusion, And Unconscious Transference, Kenneth A. Deffenbacher, Brian H. Bornstein, Steven D. Penrod
Mugshot Exposure Effects: Retroactive Interference, Mugshot Commitment, Source Confusion, And Unconscious Transference, Kenneth A. Deffenbacher, Brian H. Bornstein, Steven D. Penrod
Department of Psychology: Faculty Publications
More than 25 years of research has accumulated concerning the possible biasing effects of mugshot exposure to eyewitnesses. Two separate metaanalyses were conducted on 32 independent tests of the hypothesis that prior mugshot exposure decreases witness accuracy at a subsequent lineup. Mugshot exposure both significantly decreased proportion correct and increased the false alarm rate, the effect being greater on false alarms. A mugshot commitment effect, arising from the identification of someone in a mugshot, was a substantial moderator of both these effects. Simple retroactive interference, where the target person is not included among mugshots and no one in a mugshot …
Emotion And The Law: A Framework For Inquiry, Richard L. Wiener, Brian H. Bornstein, Amy Voss
Emotion And The Law: A Framework For Inquiry, Richard L. Wiener, Brian H. Bornstein, Amy Voss
Department of Psychology: Faculty Publications
This paper draws on research in social and cognitive psychology to show how theories of judgment and decision making that incorporate decision makers’ affective responses apply to legal contexts. It takes 2 widely used models of decision making, the rational actor and lens models, and illustrates their utility for understanding legal judgments by using them to interpret research findings on juror decision making, people’s obedience to the law (e.g., paying taxes), and eyewitness memory. The paper concludes with a discussion of the advantages of modifying existing approaches to information processing to include the influence of affect on how legal actors …
Rats’ Novel Object Interaction As A Measure Of Environmental Familiarity, Jamie L. Wilkinson, Laura Herrman, Matthew I. Palmatier, Rick A. Bevins
Rats’ Novel Object Interaction As A Measure Of Environmental Familiarity, Jamie L. Wilkinson, Laura Herrman, Matthew I. Palmatier, Rick A. Bevins
Department of Psychology: Faculty Publications
Environmental familiarization is a learning phenomenon embedded within most tasks used to study learning and motivation. Given its prevalence there is surprisingly little systematic behavioral research on factors affecting familiarization. The six experiments reported in the present report used rats’ tendency to interact more with a novel object in a familiar than in a novel environment as a measure of environmental familiarization. We found that 3 min of exposure to the environment was sufficient to increase object interaction above unfamiliar controls even when testing occurred up to 48 h after initial exposure to the environment; 1 or 1.5 min of …
The Vaccinia-Related Kinases Phosphorylate The N' Terminus Of Baf, Regulating Its Interaction With Dna And Its Retention In The Nucleus, R. Jeremy Nichols, Matthew S. Wiebe, Paula Traktman
The Vaccinia-Related Kinases Phosphorylate The N' Terminus Of Baf, Regulating Its Interaction With Dna And Its Retention In The Nucleus, R. Jeremy Nichols, Matthew S. Wiebe, Paula Traktman
Nebraska Center for Virology: Faculty Publications
The vaccinia-related kinases (VRKs) comprise a branch of the casein kinase family whose members are characterized by homology to the vaccinia virus B1 kinase. The VRK orthologues encoded by Caenorhabditis elegans and Drosophila melanogaster play an essential role in cell division; however, substrates that mediate this role have yet to be elucidated. VRK1 can complement the temperature sensitivity of a vaccinia B1 mutant, implying that VRK1 and B1 have overlapping substrate specificity. Herein, we demonstrate that B1, VRK1, and VRK2 efficiently phosphorylate the extreme N' terminus of the BAF protein (Barrier to Autointegration Factor). BAF binds to both DNA and …
Pyemotes Herfsi (Acari: Pyemotidae), A Mite New To North America As The Cause Of Bite Outbreaks, Alberto B. Broce, Ludek Zurek, James A. Kalisch, Robert Brown, David L. Keith, David Gordon, Janis Goedeke, Cal Welbourn, John Moser, Ronald Ochoa, Eduardo Azziz-Baumgartner, Fuyuen Yip, Jacob Weber
Pyemotes Herfsi (Acari: Pyemotidae), A Mite New To North America As The Cause Of Bite Outbreaks, Alberto B. Broce, Ludek Zurek, James A. Kalisch, Robert Brown, David L. Keith, David Gordon, Janis Goedeke, Cal Welbourn, John Moser, Ronald Ochoa, Eduardo Azziz-Baumgartner, Fuyuen Yip, Jacob Weber
Department of Entomology: Faculty Publications
High incidences of red, itching, and painful welts on people in the midwestern United States led to the discovery of a European species of mite, Pyemotes herfsi (Oudemans) (Acari: Pyemotidae), preying on gall-making midge larvae on oak leaves. The mites' great reproductive potential, small size, and high capacity for dispersal by wind make them difficult to control or avoid.
Herpes Simplex Virus Type 1 Icp0 Localizes In The Stromal Layer Of Infected Rabbit Corneas And Resides Predominantly In The Cytoplasm And/Or Perinuclear Region Of Rabbit Keratocytes, Naoyuki Morishige, James V. Jester, Julie Naito, Nelson Osorio, Andrew Wahlert, Clinton J. Jones, Roger D. Everett, Steven L. Weschler, Guey Chuen Perng
Herpes Simplex Virus Type 1 Icp0 Localizes In The Stromal Layer Of Infected Rabbit Corneas And Resides Predominantly In The Cytoplasm And/Or Perinuclear Region Of Rabbit Keratocytes, Naoyuki Morishige, James V. Jester, Julie Naito, Nelson Osorio, Andrew Wahlert, Clinton J. Jones, Roger D. Everett, Steven L. Weschler, Guey Chuen Perng
School of Veterinary and Biomedical Sciences: Faculty Publications
Herpes stromal keratitis (HSK) results from the reactivation of herpes simplex virus type-1 (HSV-1) in the cornea. The subsequent corneal inflammation and neovascularization may lead to scarring and visual loss. The cellular and molecular mechanisms underlying HSK remain unknown. The presence of stromal HSV-1 viral proteins or antigens in the HSK cornea remains a subject of debate. It was recently reported that HSV-1 ICP0 rapidly diffuses out of infected rabbit corneas. To investigate further the presence of HSV-1 ICP0 in the infected cornea, particularly in the corneal stroma, ex vivo confocal microscopy was used to scan rabbit corneas infected with …
A Coprological View Of Ancestral Pueblo Cannibalism, Karl Reinhard
A Coprological View Of Ancestral Pueblo Cannibalism, Karl Reinhard
Karl Reinhard Publications
As the object of my scientific study, I’ve chosen coprolites. It’s not a common choice, but to a paleonutritionist and archaeoparasitologist, a coprolite—a sample of ancient feces preserved by mineralization or simple drying—is a scientific bonanza. Analysis of coprolites can shed light on both the nutrition of and parasites found in prehistoric cultures. Dietary reconstructions from the analysis of coprolites can inform us about, for example, the origins of modern Native American diabetes. With regard to parasitology; coprolites hold information about the ancient emergence and spread of human infectious disease. Most sensational, however, is the recent role of coprolite analysis …
Lysine Residues In N-Terminal And C-Terminal Regions Of Human Histone H2a Are Targets For Biotinylation By Biotinidase, Yap Ching Chew, Gabriela Camporeale, Nagarama Kothapalli, Gautam Sarath, Janos Zempleni
Lysine Residues In N-Terminal And C-Terminal Regions Of Human Histone H2a Are Targets For Biotinylation By Biotinidase, Yap Ching Chew, Gabriela Camporeale, Nagarama Kothapalli, Gautam Sarath, Janos Zempleni
Department of Nutrition and Health Sciences: Faculty Publications
In eukaryotic cell nuclei, DNA associates with the core histones H2A, H2B, H3 and H4 to form nucleosomal core particles. DNA binding to histones is regulated by posttranslational modifications of N-terminal tails (e.g., acetylation and methylation of histones). These modifications play important roles in the epigenetic control of chromatin structure. Recently, evidence that biotinidase and holocarboxylase synthetase (HCS) catalyze the covalent binding of biotin to histones has been provided. The primary aim of this study was to identify biotinylation sites in histone H2A and its variant H2AX. Secondary aims were to determine whether acetylation and methylation of histone H2A affect …
Forensic Interviewing In Child Sexual Abuse Cases: Current Techniques And Future Directions, Lindsay E. Cronch, Jodi L. Viljoen, David J. Hansen
Forensic Interviewing In Child Sexual Abuse Cases: Current Techniques And Future Directions, Lindsay E. Cronch, Jodi L. Viljoen, David J. Hansen
Department of Psychology: Faculty Publications
In child sexual abuse cases, skillful forensic interviews are important to ensure the protection of innocent individuals and the conviction of perpetrators. Studies have examined several factors that influence disclosure during interviews, including both interviewer and child characteristics. Numerous interviewing techniques have received attention in the literature, including allegation blind interviews, open-ended questioning, cognitive interviewing, the Touch Survey, truth–lie discussions, and anatomical dolls. Recent studies have examined new directions in forensic interviewing, such as structured interview protocols and the extended forensic evaluation model. In addition, the child advocacy center model has been established as a strategy to prevent repeated interviewing. …
Toward A Formal Theory Of Flexible Spatial Behavior: Geometric Category Biases Generalize Across Pointing And Verbal Response Types, John P. Spencer, Vanessa R. Simmering, Anne R. Schutte
Toward A Formal Theory Of Flexible Spatial Behavior: Geometric Category Biases Generalize Across Pointing And Verbal Response Types, John P. Spencer, Vanessa R. Simmering, Anne R. Schutte
Department of Psychology: Faculty Publications
Three experiments tested whether geometric biases—-biases away from perceived reference axes—-reported in spatial recall tasks with pointing responses generalized to a recognition task that required a verbal response. Seven-year-olds and adults remembered the location of a dot within a rectangle and then either reproduced its location or verbally selected a matching choice dot from a set of colored options. Results demonstrated that geometric biases generalized to verbal responses; however, the spatial span of the choice set influenced performance as well. These data suggest that the same spatial memory process gives rise to both response types in this task. Simulations of …
Bovine Herpesvirus 1 Immediate-Early Protein (Bicp0) Interacts With The Histone Acetyltransferase P300, Which Stimulates Productive Infection And Gc Promoter Activity, Yange Zhang, Yunquan Jiang, Vicki Geiser, Joe Zhou, Clinton J. Jones
Bovine Herpesvirus 1 Immediate-Early Protein (Bicp0) Interacts With The Histone Acetyltransferase P300, Which Stimulates Productive Infection And Gc Promoter Activity, Yange Zhang, Yunquan Jiang, Vicki Geiser, Joe Zhou, Clinton J. Jones
School of Veterinary and Biomedical Sciences: Faculty Publications
The immediate-early protein, bICP0, of Bovine herpesvirus 1 (BHV-1) transactivates viral promoters and stimulates productive infection. bICP0 is expressed constitutively during productive infection, as its gene contains an immediate- early and an early promoter. Like other ICP0 homologues encoded by members of the subfamily Alphaherpesvirinae, bICP0 contains a zinc RING finger located near its N terminus. Mutations that disrupt the bICP0 zinc RING finger impair its ability to activate transcription, stimulate productive infection, inhibit interferon-dependent transcription in certain cell types and regulate subnuclear localization. bICP0 also interacts with a cellular chromatin-remodeling enzyme, histone deacetylase 1 (HDAC1), and can relieve …
Lnteroceptive Pavlovian Conditioning With Nicotine As The Conditional Stimulus Varies As A Function Of The Number Of Conditioning Trials And Unpaired Sucrose Deliveries, Jamie L. Wilkinson, Jennifer E. Murray, Chia Li, Steven M. Wiltgen, Rachel D. Penrod, Sarah A. Berg, Rick A. Bevins
Lnteroceptive Pavlovian Conditioning With Nicotine As The Conditional Stimulus Varies As A Function Of The Number Of Conditioning Trials And Unpaired Sucrose Deliveries, Jamie L. Wilkinson, Jennifer E. Murray, Chia Li, Steven M. Wiltgen, Rachel D. Penrod, Sarah A. Berg, Rick A. Bevins
Department of Psychology: Faculty Publications
In rats, the pharmacological (interoceptive) effects of nicotine can serve as a signal (conditional stimulus) in a Pavlovian (classical) conditioning task. In this task, nicotine administration (0.4 mg base/kg, subcutaneous) is typically paired with intermittent access to a liquid sucrose unconditional stimulus; sucrose is withheld on saline sessions. An increase in sucrose receptacle entries (goal tracking) on nicotine sessions indicates conditioning. Given our limited understanding of the functional relationships controlling conditioned responding to a nicotine conditional stimulus, the present research examined nicotine's sensitivity to several manipulations shown to affect the conditioned responding in more widely studied Pavlovian conditioning tasks that …