Digital Commons Network^™

Attitudes And Perceptions Of Nurses Regarding Early Communication Intervention, Brenda Louw, Ingrid Weber

Brenda Louw

Strategic Napping, Scott A. Shappell, Douglas A. Wiegmann

Scott Shappell

Epilepsy, Michael Rogawski

Michael A. Rogawski

No abstract provided.

Why I Am A Psychiatric Scientist, Kevin J. Black

Kevin J. Black, MD

No abstract provided.

Mortality From Asthma In State Of Sao Paulo (1970-92), Paulo A. Lotufo

Paulo A Lotufo

No abstract provided.

Myocardial Alpha-Thrombin Receptor Activation Induces Hypertrophy And Increases Atrial Natriuretic Factor Gene Expression, C C. Glembotski, C E. Irons, K A. Krown, S F. Murray, A B. Sprenkle, C A. Sei

Amy Sprenkle

Modulation Of Mhc Expression On Human Endothelial-Cells By Sera From Patients With Systemic Lupus-Erythematosus, Mary Anne Tan Jin Ai

Mary Anne Tan Jin Ai

Major histocompatibility complex (MHC) antigen expression on cells is a prerequisite for immune interaction with activated T-cells. This study examined the ability of sera from patients with systemic lupus erythematosus (SLE) to modulate MHC expression on vascular endothelial cells. SLE sera were able to selectively upregulate MHC class I antigen expression on cultured human umbilical venous endothelial (HUVE) cells, without concomitant induction of MHC class II antigen. The stimulation index (SI) for MHC class I expression produced by SLE sera (1.21 ± 0.23) was significantly higher than those for normal controls (1.01 ± 0.10) (P < 0.0001) and non-SLE patients (1.12 ± 0.14) (P < 0.05). Additionally, active SLE patients had higher mean SI than inactive patients (P < 0.001). Preincubation of SLE sera with Protein A-Sepharose beads conjugated with antibodies against tumor necrosis factor-α and interferon-α was able to significantly reduce their ability to upregulate class I MHC expression by HUVE cells, indicating that these cytokines were responsible for the modulatory effect. This could be an important mechanism for the immune-mediated vascular injury seen in SLE.

Harpoon Extraction Of A Common Bile Duct Stone Impacted At The Ampulla Of Vater With Needle-Knife Sphincterotome., Vivian C. Mcalister, Andre Roy, Ron Passi

Vivian C. McAlister

The urgency of dealing with impacted ampullary stones is underlined in the first case reported by Opie6 at the autopsy of a young woman. Impacted ampullary stones that prevent papillary cannulation and standard sphincterotomy make up less than 5% of common bile duct stones seen at ERCP.3 Several series suggest the safe use of needle-knife sphincterotomy to create a choledochoduodenal fistula or to allow subsequent standard sphincterotomy in this situation. These series have also reported failure to extract the stone so that surgical removal was required.3,4Successful sphincterotomy may facilitate the early diagnosis of tumors that cause the ampulla to bulge. …

The Alpha-Adrenergic Stimulation Of Atrial Natriuretic Factor Expression In Cardiac Myocytes Requires Calcium Influx, Protein Kinase C, And Calmodulin-Regulated Pathways, C A. Sei, C E. Irons, A B. Sprenkle, P M. Mcdonough, J H. Brown, C C. Glembotski

Amy Sprenkle

Mood Induction, Interpersonal Perceptions, And Behavioral Rejection In Students With Depressed, Non-Depressed Disturbed, And Normal Roommates, Charles A. Sanislow, David V. Perkins, Deborah Ware Balogh

Charles A. Sanislow, Ph.D.

The present study used the Minnesota Multiphasic Personality Inventory (MMPI) to select, based on multidimensional criteria, 51 college students who displayed depression alone, depression in conjunction with other psychological disturbance (PD), nondepressive PD, or no PD. All students had been living with randomly assigned roommates (RMs) for at least 10 wks. RMs of these students completed the Multiple Affect Adjective Check List, the Profile of Mood States, MMPI-168 Depression scale items, and items concerning roommate behavior. RMs of students depressed in conjunction with other PD were significantly more depressed themselves on 2 measures than were RMs of students in the …

Norm-Of-Reaction: Definition And Misinterpretation Of Animal Research, Steve A. Platt, Charles A. Sanislow

Charles A. Sanislow, Ph.D.

The development of a phenotype is due to an interaction of the genotype with the environment. Two terms have been used to describe the outcome of this interaction, the norm-of-reaction and the reaction range. The first represents the theoretically limitless distribution of the phenotypes that may be expressed by a given genotype. The reaction range implies an upper and lower limit for phenotype expression possible from a given genotype. A critical distinction between the reaction range and the norm-of-reaction is that the norm-of-reaction is a statement of the conceivable interactions found but does not imply any predictability other than that …

Curative Factors In Offenders' Groups, John W. Macdevitt, Charles A. Sanislow

Charles A. Sanislow, Ph.D.

Curative factors were assessed among therapy groups of offenders experiencing differentially restrictive incarceration, from probation through minimum security and maximum security to a special segregation unit for behaviorally problematic prisoners. Catharsis was highly rated as in earlier studies, while interpersonal learning input was rated at varying levels. Existential awareness was rated much higher than with typical outpatient populations, while cohesiveness was rated lower. The significance of these findings is discussed.

The Insanity Defense: The Insanity Plea. By William J. Winslade And Judith Wilson Ross. New York: Charles Scribner's Sons, Donald H. J. Hermann

Donald Hermann

No abstract provided.

Hereditary Angioneurotic Oedema--The Management Of The Problem In A Family, Vivian C. Mcalister, N Boland, I H. Al-Abdullah, J Greally

Vivian C. McAlister

Diagnosis and treatment of hereditary angioneurotic oedema (HAO) is described in a family. C1 esterase inhibitor (C1 INH) deficiency was confirmed with radial immunodiffusion and functional assays. The effect of treament with combinations of tranexamic acid, danazol and stanozolol on C1 INH levels are reported.