Digital Commons Network^™

Atrial Fibrillation And Stroke In Elderly Patients, Geetanjali Dang, Imaan Jahangir, Jasbir Sra, A. Jamil Tajik, Arshad Jahangir

Jasbir Sra, MD, FACC, Program Director

The increasing prevalence of stroke, with an estimated annual cost of $71.5 billion, has made it a major health problem that increases disability and death, particularly in patients with atrial fibrillation. Although advanced age and atrial fibrillation are recognized as strong risk factors for stroke, the basis for this susceptibility are not well defined. Aging or associated diseases are accompanied by changes in rheostatic, humoral, metabolic and hemodynamic factors that may contribute more to stroke predisposition than rhythm abnormality alone. Several thromboembolism-predisposing clinical characteristics and serum biomarkers with prognostic significance have been identified in patients with atrial fibrillation. Although anticoagulation …

A Prescription At Discharge Improve Short And Long Term Adherence, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Ihome: Ipad Application For Stoke Rehab At Home, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

The Art Of Estimating Outcomes And Treating Patients With Stroke In The 21st Century., Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Pulmonary Embolism After Stroke, Gustavo Saposnik

Gustavo Saposnik

BACKGROUND: Limited information is available on the frequency of pulmonary embolism (PE) in patients with an acute ischemic stroke (AIS). We evaluated clinical characteristics, predisposing factors, and outcomes in AIS patients with PE.

METHODS AND RESULTS: We included all AIS patients admitted to participating institutions in the Registry of the Canadian Stroke Network. Clinically PE was documented by a physician and confirmed by computed tomography pulmonary angiography within 30 days of the stroke case index. The primary outcome was death or disability at discharge. Secondary outcomes included disposition, length of hospital stay, mortality at 3 months and 1 year. Among …

Validation Of Stroke Prognostic Scores: What Do Clinicians Need To Know?, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

The Plan Score, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Clopidogrel Hypersensitivity: Clinical Challenges And Options For Management., Kimberly L Campbell, John R Cohn, Michael P Savage

Michael P Savage M.D.

Over 90 million patients have been prescribed clopidogrel since its US FDA approval in 1997. Clopidogrel hypersensitivity affects up to 6% of patients, most commonly in the form of a pruritic rash. Symptoms are severe enough to result in drug discontinuation in 1.5% of patients. Premature discontinuation of clopidogrel is problematic following percutaneous coronary intervention because of the risk of stent thrombosis leading to myocardial infarction and death. Accordingly, the management of patients with clopidogrel hypersensitivity is of significant clinical importance. Conventional clopidogrel desensitization protocols, while successful in most patients, employ a washout period off medication to enable accurate detection …

Intracerebral Hemorrhage In Cerebral Venous Thrombosis, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Virtual Reality In Stroke Rehabilitation: A Meta-Analysis And Practical Implications For Clinicians, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Organized Outpatient Stroke Care, Gustavo Saposnik

Gustavo Saposnik

Background and Purpose—Organized inpatient stroke care decreases mortality and morbidity irrespective of patient age, stroke severity, or stroke subtype. Limited information is available on whether organized outpatient care models such as stroke prevention clinics (SPC) improve outcomes after a transient ischemic attack or ischemic stroke. We compared 1-year mortality and stroke readmission in patients with transient ischemic attack or ischemic stroke referred versus not referred to an SPC. Methods—This was a retrospective cohort study including 16 468 consecutive patients with ischemic stroke or transient ischemic attack who were seen in the emergency department or admitted to a hospital between July …

Penumonia: Risk Factors And Outcomes After Stroke, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Care And Outcomes In Patients With Ischemic Stroke With And Without Preexisting Dementia, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Aha Guidelines For The Management Of Cerebral Venous Thrombosis, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Stroke Prevalence In A Poor Neighbourhood Of Sao Paulo, Brazil: Applying A Stroke Symptom Questionnaire, Paulo A. Lotufo

Paulo A Lotufo

Background Brazil has one of the highest stroke mortality rates in the world, these rates are most endemic in the poor. We verified the prevalence of stroke in a deprived neighbourhood in the city of Sa˜ o Paulo, Brazil and compared it with other surveys worldwide. Methods A questionnaire with six questions concerning limb and facial weakness, articulation, sensory disturbances, impaired vision, and past diagnosis of stroke was completed door-to-door in a well-defined area of 15 000 people. Questionnaires were considered positive when a participant answered two or more questions about stroke symptoms or the presence of stroke being confirmed …

Association Between Weekend Hospital Presentation And Stroke Fatality, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Risk Of Premature Stroke In Recent Immigrants (Presario): Population-Based Matched Cohort Study., Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Myocardial Infarction Associated With Recency Of Immigration To Ontario., Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Stroke Mortality In Brazil: One Example Of Delayed Epidemiological Cardiovascular Transition, Paulo A. Lotufo

Paulo A Lotufo

No abstract provided.

Stroke In The Very Elderly: Hospital Care, Case Fatality And Disposition., Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Age Disparities In Stroke Quality Of Care And Delivery Of Health Services., Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Socioeconomic Status, Hospital Volume, And Stroke Fatality In Canada., Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Applying The Evidence: Do Patients With Stroke, Coronary Artery Disease, Or Both Achieve Similar Treatment Goals?, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Do All Age Groups Benefit From Organized Inpatient Stroke Care?, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Escalating Levels Of Access To In-Hospital Care And Stroke Mortality., Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Stroke Outcome In Those Over 80: A Multicenter Cohort Study Across Canada., Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Weekends: A Dangerous Time For Having A Stroke?, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.

Hospital Volume And Stroke Outcome: Does It Matter?, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.