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Investigation Of Bax Vdac Interactions And Their Relationship Regarding Apoptosis In Drosophila Melanogaster, John Sullivan Jan 2014

Investigation Of Bax Vdac Interactions And Their Relationship Regarding Apoptosis In Drosophila Melanogaster, John Sullivan

Honors Theses

Cell mediated death, or apoptosis, is a critical biological process that once fully understood could unlock a potentially new understanding of the mechanisms of both cancer and neurodegenerative diseases. The general mechanism of apoptosis includes cytochrome c being released from the mitochondrial membrane through a channel created by an activated pro-apoptotic BH123 protein. Once the cytochrome c leaves the mitochondrial membrane it goes on to ultimately activate a caspase cascade, which results in cell apoptosis. Similar to BH123 channels, VDACs (voltage-dependent anion channels) are also pore-forming proteins that regulate the intake and output of metabolites from the mitochondrial intermembrane space …


Preliminary Investigations Into The Population Genetics Of The Horned Passalus Beetle, Odontotaenius Disjunctus (Coleoptera), In Forests Of The Southeastern United States, Rachel Yi Jan 2014

Preliminary Investigations Into The Population Genetics Of The Horned Passalus Beetle, Odontotaenius Disjunctus (Coleoptera), In Forests Of The Southeastern United States, Rachel Yi

Honors Theses

As a major hotspot of biodiversity, the Appalachian Mountains have been a source of great interest for ecologists in many ways. The mountains' north-south orientation, varying degrees of elevation and environmental conditions, and historical cycles of glacial encroachment have been thought to contribute to this unusual level of population variation. As such, population genetic studies of species have been a growing area of investigation. Phylogeography, the study of how historical processes could lead to current geographic distributions of individuals and populations of a species, is a particularly prominent direction. The focus of this study examines the horned passalus and its …


An Evaluation Of Soil Extracellular Enzyme Activity In Response To Burning As A Forest Restoration Technique, William M. Steward Jan 2014

An Evaluation Of Soil Extracellular Enzyme Activity In Response To Burning As A Forest Restoration Technique, William M. Steward

Honors Theses

Burning is a method of forest restoration with the goal of returning natural tree species to ecosystems. Burning has a wide range of effects on an ecosystem, including the alteration of important soil processes and characteristics. One of the key components of soil is the activity of extracellular enzymes, which can be used to provide insight into the nutritional requirements of soil microbes as well as nutrient availability and cycling. Because enzymes are important in the overall functioning of soil and can be used to assess soil health, there is great need to examine the effects of burning on soil …


Octocoral Physiology: Calcium Carbonate Composition And The Effect Of Thermal Stress On Enzyme Activity, Hadley Pearson Jan 2014

Octocoral Physiology: Calcium Carbonate Composition And The Effect Of Thermal Stress On Enzyme Activity, Hadley Pearson

Honors Theses

Octocorals are a diverse group of organisms, and within the Caribbean they contribute substantially to coral-reef cover. In this thesis, two different studies performed on these marine organisms are detailed. In Section I, the percent calcium carbonate composition of several species was analyzed. Octocorals produce sclerites: calcium carbonate crystals that serve as the skeletal elements of the coral. Determining the percent calcium carbonate composition of eight Caribbean octocoral species can give comparative insight into the form and function in these animals. This study also offers clues about potential evolutionary tradeoffs between rigidity and flexibility, as well as establishes some basic …


Attempts To Determine The Community Structure Of Archaea In Major Tributaries Of The Mississippi River, Thomas Douglas Bateman Jan 2014

Attempts To Determine The Community Structure Of Archaea In Major Tributaries Of The Mississippi River, Thomas Douglas Bateman

Honors Theses

Archaea were once thought to be limited to extreme environments, but it has now been established that they are found in diverse ecosystems worldwide. Archaea may possess distinctive properties that affect biogeochemical processes, which makes understanding their distribution crucial in determining their effect on these processes. Little research has been done on the ecology of Archaea in rivers, and this study represents the first attempt to gain an understanding of the diversity of Archaea within major tributaries of the Mississippi River. Polymerase Chain Reaction (PCR) amplification of archaeal DNA and denaturing gradient gel electrophoresis (DGGE) was used to examine community …


Meta-Analysis Of Melanoma Incidence In The United States: Demographic Variation And Relationship With Uv Index And Latitude, Charles Thomas Pritchard Jan 2014

Meta-Analysis Of Melanoma Incidence In The United States: Demographic Variation And Relationship With Uv Index And Latitude, Charles Thomas Pritchard

Honors Theses

A link between exposure to ultraviolet (UV) radiation and melanoma skin cancer formation has generally been accepted in the scientific community, but precise quantification of such a link into a predictive equation is difficult to find in scientific literature. It was the aim of this study to determine if a quantifiable relationship exists between UV exposure and melanoma rates in the United States. Prior to the initiation of this study, it was hypothesized that existing predictive equations using accumulated UV index and latitude for general skin cancer incidence (i.e., including both melanoma and non-melanoma skin cancers) in Chile would be …


Electromyography Of Mastication Muscles In College Athletes, John Ratliff Jan 2014

Electromyography Of Mastication Muscles In College Athletes, John Ratliff

Honors Theses

The purpose of this experiment was to determine if co-activation in enhanced neck muscles increased surface electromyography (sEMG) activity in the masseter while chewing with the 1st, 2nd, and 3rd molars. Sixteen football players from The University of Mississippi volunteered for this study. Football players were examined because they strengthen their neck 4 days a week to help prevent neck injuries and concussions. Participants' average body fat was 15.68% and average body mass was 100.69 kilograms showing that the participants were larger, muscular individuals compared to non student-athletes and represent a unique, study group. Participants performed maximum weight on a …


Understanding The Karoo: Investigating The Function Of A Copulation Call In Female Wild Turkeys Meleagris Gallopavo, Callie Grey Jan 2014

Understanding The Karoo: Investigating The Function Of A Copulation Call In Female Wild Turkeys Meleagris Gallopavo, Callie Grey

Honors Theses

Even with the vast amount of research regarding mating vocalizations and their adaptive functions, the copulation call of female wild turkeys, Meleagris gallopavo, has yet to be described. The purpose of this study was to describe this novel call, referred to as karoo and to test three hypotheses for its function. Previously collected data in the form of video tapes and data sheets provided the basis of this study. Dr. Richard Buchholz conducted experimental trials in 2008 and 2009. Male behavioral data was recorded on the videos. The videos and the data sheets were used to collect female behavioral data. …


Host-Specialization Of Bartonella In Flea Vectors Collected From Black-Tailed Prairie Dogs, Mark D. Massaro Jan 2014

Host-Specialization Of Bartonella In Flea Vectors Collected From Black-Tailed Prairie Dogs, Mark D. Massaro

Honors Theses

At least 22 species of Bartonella bacteria have been named and many are associated with one of a list of potential mammalian reservoirs and arthropod vectors. One example of such a system is the parasitism of black-tailed prairie dogs (Cynomys ludovicianus) of the Western U.S. by Oropyslla hirsuta and Pulex simulans fleas. These vectors are thought to maintain B. washoensis infection in these mammals, but little is known about their role in the specialization of this strain to this reservoir. We found that the more specialist O. hirsuta fleas were much more likely to be infected with B. washoensis than …


Evaluation Of Microbial Diversity Present In Herbal Supplements As Revealed By Pcr-Based 16s Sequence Analysis, Stephen Stone Jan 2014

Evaluation Of Microbial Diversity Present In Herbal Supplements As Revealed By Pcr-Based 16s Sequence Analysis, Stephen Stone

Honors Theses

Over the last few decades people have become more aware of their general wellness and have turned towards alternative measures to ensure good health. One of these alternative measures, the herbal supplement market, has risen significantly in recent years, even though there is no conclusive research that points to the effectiveness of herbal supplements. Also, because of sparse regulation from the FDA, there are many questions related to the efficacy, composition, processing methods, and, consequently, safety of these supplements. The aim of this study was to determine the microbial composition of herbal supplements in an attempt to identify potential targets …


The Effects Of Adrenergic Antagonists On Spatial Memory In The Zebra Finch (Taeniopygia Guttata), Taylor Williams Jan 2014

The Effects Of Adrenergic Antagonists On Spatial Memory In The Zebra Finch (Taeniopygia Guttata), Taylor Williams

Honors Theses

The adrenergic system appears to be involved in the consolidation and reconsolidation of hippocampally dependent spatial memories in mammals. Based on connectivity, cell types, ontogeny and receptor distribution, the avian hippocampus is thought to be a homolog to the mammalian hippocampus. The adrenergic system appears to be fairly conserved but may show some species specializations. To determine if the adrenergic system plays a role in spatial learning and memory in birds, we used a series of experiments to investigate the role of α- and β-adrenergic receptors on spatial navigation and memory in an avian species, zebra finches, using the Day …