Psychiatric and Mental Health Commons^™

Attachment Styles And Trust Propensity In Females With Borderline Personality Disorder, Jacob Matthew White

Graduate Theses and Dissertations

Borderline Personality Disorder (BPD) is one of the most frequently encountered and complex disorders in mental health care. Interpersonal impairment is a central issue for individuals with BPD. This complex disorder has received negative stigma along with historically more females than males receiving this diagnosis (Linehan, 1993). Therefore, this study examined a clinical sample of 30 females diagnosed with BPD. Through the collection of data this study used the following measures: a basic demographic questionnaire gathering specific age, ethnicity, current relationship status, parental relationship status, the Experiences in Close Relationships Scale (ECR; Brennan, Clark & Shaver, 1998), and the Propensity …

Suicide And Disability: Three Different Analyses Of A Nation-Wide Sample Of American Adults, Emily M. Lund

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Suicide is a major public health issue and the 10^th leading cause of death in the U.S. People with disabilities are one group that may be at high risk for suicide. This dissertation presents three studies that examined suicidal thoughts and behaviors in a national sample of individuals with and without disabilities. They also examined the ways in which depression scores and sociodemographic factors such as gender, religion, race, and employment, interact with disability status to influence suicidality. I found that people with disabilities reported more suicidal thoughts and suicide attempts and were more likely to believe that they …

Searching Neuroimaging Biomarkers In Mental Disorders With Graph And Multimodal Fusion Analysis Of Functional Connectivity, Hao He

Electrical and Computer Engineering ETDs

Mental disorders such as schizophrenia (SZ), bipolar (BD), and major depression disorders (MDD) can cause severe symptoms and life disruption. They share some symptoms, which can pose a major clinical challenge to their differentiation. Objective biomarkers based on neuroimaging may help to improve diagnostic accuracy and facilitate optimal treatment for patients. Over the last decades, non-invasive in-vivo neuroimaging techniques such as magnetic resonance imaging (MRI) have been increasingly applied to measure structure and function in human brains. With functional MRI (fMRI) or structural MRI (sMRI), studies have identified neurophysiological deficits in patients’ brain from different perspective. Functional connectivity (FC) analysis …

An Overview Of Limited Literature On Diagnosis And Treatment Of Deaf And Hard Of Hearing Individuals With Pediatric Bipolar Disorder, Hannah A. Joharchi, Carolyn A. Corbett, Michele Dadson

JADARA

The current literature indicates children and adolescents with bipolar disorder and severe mood dysregulation find it more difficult to make decisions, recognize facial display of emotions, etc. (McClure, et. al, 2005; Rich, Grimley, Schmajuk, Blair, Blair, & Leibenluft, 2008; Kim, et. al, 2013). While treatment with this population is unclear (Miklowitz, et. al, 2013; Miklowitz, et. al, 2014), there is even less literature pertaining to treatment with d/Deaf and hard of hearing (DHH) children who have bipolar disorder. An additional challenge for DHH individuals with bipolar disorder is access to treatment (McClure, et. al, 2005; Rich, Grimley, Schmajuk, Blair, Blair, …

Models For Predicting Incident Delirium In Hospitalized Older Adults: A Systematic Review, Sundeep Kalimisetty, Wajih Askar, Brenda Fay, Ariba Khan

Journal of Patient-Centered Research and Reviews

Background: Delirium is common in hospitalized older adults, and 40% of cases may be preventable. Hospital Elder Life Program is an evidence-based program to reduce incidence of delirium. It has been successfully implemented in one hospital and will be implemented in four other hospitals. Identification of patients at highest risk of developing delirium using the electronic health record (EHR) may be an effective targeted strategy to reduce the incidence of delirium.

Purpose: To systematically review and summarize the medical literature regarding risk prediction models for delirium in older inpatients.

Methods: A medical librarian customized and conducted the search strategy for …

Positive Allosteric Modulator Of Gabab Receptor Alters Behavioral Effects But Not Afterdischarge Progression Induced By Partial Hippocampal Kindling., L Stan Leung, Miao Jin, Liangwei Chu, Jingyi Ma

Physiology and Pharmacology Publications

Hippocampal seizures decreased the function of GABAB receptors, which may further increase seizure susceptibility and contribute to development of schizophrenia-like behaviors. Recent literature indicates that GABAB receptor agonist may normalize schizophrenia-like behaviors and prevent drug-induced behavioral sensitization. We hypothesized that positive modulation of GABAB receptor function during seizure induction will reduce seizure-induced schizophrenia-like behaviors. Using a partial hippocampal kindling model, afterdischarges were induced after injection of saline or dimethyl sulfoxide (vehicle-kindled rats), or a GABAB receptor positive allosteric modulator CGP7930, at 1 mg/kg i.p. (CGP1-kindled) or 5 mg/kg i.p. (CGP5-kindled). The increase in the primary afterdischarge duration during kindling was …

Detrending Changes The Temporal Dynamics Of A Semantic Fluency Task, Steven Lenio, Frances M. Lissemore, Martha Sajatovic, Kathleen A. Smyth, Curtis Tatsuoka, Wojbor A. Woyczynski, Alan J. Lerner

Faculty Scholarship

Objective: To study the dynamics of clustering semantic fluency responses and switching between clusters. Methods: We conducted a cross-sectional study of participants (N = 60) in a study of patient reported outcomes who were given the Saint Louis University Mental Status test. Sixty-second animal naming tests were scored for the timing of responses as well as the clustering of responses into semantic categories. Time scores were detrended to correct for exponential exhaustion and normalize the time scale across individuals. Results: Grouped by number of responses given, low performers (LP; Carter et al., 2012) switched between clusters fewer times than medium …

Renew, Kishauna Grant

Learning Showcase 2016: A Celebration of Discovery, Transformation and Success

Concord, COVA and Syntero provide an intensive hospital diversion program with the goal to keep young adults from a second psychiatric hospitalization and costly ongoing mental health treatment. Program elements include counseling, case management, psychiatry appointments and medication when needed, family education and vocational assistance to allow healing outside the hospital. Success is measured as a percentage of program participants re-hospitalized for one year after entering program versus control group at start of program of 47% re-hospitalization; and percentage of participants engaged in employment or engaged in education or training with a goal of 60%. Concord is also partnering with …

Ptsd, Tbi, And Oth Discharges: A Case Study Of A Young Service Member, Patricia E. Roberts

Faculty Publications

No abstract provided.

Structural Dichotomy Of The Mind; The Role Of Sexual Neuromodulators, Ion G. Motofei, David L. Rowland

Journal of Mind and Medical Sciences

The mind (mental function) and sexuality represent two distinct environmental functions, but which are supported within the brain by a common (somatic-autonomic) neurobiological substrate. As a consequence, mental function takes on autonomic characteristics from the sexual-autonomic system (like autonomy, duality), while sexual function takes on features from mental functioning (such as lateralization). In this paper we discuss the lateralized action of two classes of sexual neuromodulators: hormones and pheromones. This process of lateralization is assimilated with the structural dichotomy of the mind.

A relatively similar process but related to informational dichotomy of the mind will be presented in a forthcoming …

The Postfinasteride Syndrome; An Overview, David L. Rowland, Ion G. Motofei, Florian Popa, Vlad D. Constantin, Adriana Vasilache, Ioana Păunică, Cristian Bălălău, Georgeta P. Păunică, Petrisor Banu, Stana Păunică

Journal of Mind and Medical Sciences

As a 5-α reductase inhibitor, Finasteride has proven effective in ameliorating two conditions documented to be androgen dependent, namely male androgenic alopecia and benign prostatic hyperplasia. Therapeutic results are maintained as long as the drug is administered, with treatment cessation generally leading to the return of symptomatology for each condition. In addition, during the therapeutic phase, several adverse effects have been reported, some of which persist long or indefinitely after treatment cessation, known as “post-finasteride syndrome.”

Herein we present and discuss the most common finasteride side effects, along with a psycho-neuroendocrine rationale that could explain the persistence of many adverse …

Late Life Bipolar Disorder Evolving Into Frontotemporal Dementia Mimic, Martha Sajatovic

Faculty Scholarship

Objectives: Although bipolar disorder has been understood classically as a cyclic disease with full recovery between mood episodes, in the last decade, evidence has accumulated supporting progressive features. The clinical picture of advanced or end-stage bipolar disorder is heterogeneous with possible deficits in cognition and behavior, as illustrated by our case series. Cases: From our neuropsychiatric outpatient clinic, we describe four cases with bipolar disorder gradually developing a clinical syndrome, including apathy, disinhibition, loss of empathy, stereotypical behavior, and compulsiveness, fulfilling the criteria for possible behavioral variant frontotemporal dementia. All cases were diagnosed with bipolar 1 disorder at least 10 …

Characteristics Of Binge Eating Disorder In Relation To Diagnostic Criteria, Denise Wilfley, Leslie Citrome, Barry Herman

NYMC Faculty Publications

The objective of this review was to examine the evidentiary basis for binge eating disorder (BED) with reference to the Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM-5) diagnostic criteria for BED. A PubMed search restricted to titles and abstracts of English-language reviews, meta-analyses, clinical trials, randomized controlled trials, journal articles, and letters using human participants was conducted on August 7, 2015, using keywords that included "binge eating disorder," DSM-5, DSM-IV, guilt, shame, embarrassment, quantity, psychological, behavior, and "shape and weight concerns." Of the 257 retrieved publications, 60 publications were considered relevant to discussions related to DSM-5 …

Study On Influencing Factors Of Seafarers’ Mental Health And Precautions Of Psychological Diseases And Related Intervention Mechanism Under The Mlc, 2006, Xiaoli Ouyang

Maritime Safety & Environment Management Dissertations (Dalian)

No abstract provided.

Online Information Seeking By Patients With Bipolar Disorder: Results From An International Multisite Survey, Jörn Conell, Rita Bauer, Tasha Glenn, Martin Alda, Raffaella Ardau, Bernhard T. Baune, Michael Berk, Yuly Bersudsky, Amy Bilderbeck, Alberto Bocchetta, Letizia Bossini, Angela Marianne Paredes Castron, Eric Yat Wo Cheung, Caterina Chillotti, Sabine Choppin, Maria Del Zompo, Rodrigo Dias, Seetal Dodd, Anne Duffy, Bruno Etain, Andrea Fagiolini, Julie Garnham, John Geddes, Jonas Gidebro, Ana Gonzalez-Pinto, Guy M. Goodwin, Paul Grof, Hirohiko Harima, Stefanie Hassel, Chantal Henry, Diego Hidalgo-Mazzei, Vaisnvy Kapur, Girish Kunigiri, Beny Lafer, Chun Lam, Erik Roj Larsen, Ute Lewitzka, Ramus Licht, Anne Hvenegaard Lund, Blazej Misiak, Patryk Piotrowski, Scott Monteith, Rodrigo Munoz, Takako Nakanotani, René E. Nielsen, Claire O'Donovan, Yasushi Okamura, Yamima Osher, Andreas Reif, Philipp Ritter, Janusz K. Rybakowski, Kemal Sagduyu, Brett Sawchuk, Elon Shwartz, Ângela Miranda Scippa, Claire Slaney, Ahmad Hatim Sulaiman, Kirsi Suominen, Aleksandra Suwalska, Peter Tam, Yoshitaka Tatebayashi, Leonardo Tondo, Eduard Vieta, Maj Vinberg, Biju Viswanath, Julia Volkert, Mark Zetin, Iñaki Zorrilla, Peter C. Whybrow, Michael Bauer

Marriage and Family Therapy Faculty Articles and Research

Background

Information seeking is an important coping mechanism for dealing with chronic illness. Despite a growing number of mental health websites, there is little understanding of how patients with bipolar disorder use the Internet to seek information.

Methods

A 39 question, paper-based, anonymous survey, translated into 12 languages, was completed by 1222 patients in 17 countries as a convenience sample between March 2014 and January 2016. All patients had a diagnosis of bipolar disorder from a psychiatrist. Data were analyzed using descriptive statistics and generalized estimating equations to account for correlated data.

Results

976 (81 % of 1212 valid responses) …

A Case Study Using The Biopsychosocial Vulnerability-Stress Model As A Framework To Understand The Incarceration Experience, Annette T. Maruca

Journal for Evidence-based Practice in Correctional Health

In the United States, the Center for Disease Control estimates that about 80% of incarcerated inmates have a substance abuse problem. More than one fourth of inmates are in prisons because of drug related arrests. Additionally, many inmates have cooccurring mental illness disorders as well as health related issues. A multiple (four) case study design was used to explore the association between co-occurring diagnoses, antisocial traits and challenging behaviors within the incarcerated population. The analysis revealed that the four co-occurring diagnoses studied did contribute to poor health outcomes. Study findings suggest that there is a great need to create services …

Symptoms, Contributing Factors, And Screening For Perinatal Mood And Anxiety Disorders In U.S. Latinas: A Literature Review, Jennifer N. S. Massie

Master's Projects and Capstones

This literature review was conducted to gather the published information on the topic of perinatal mood and anxiety disorders in the Latina population in the United States. Academic databases were searched for articles published between 2005 and 2016. 60 articles were considered, and a final sample of 36 articles and websites was included in this review.

Evidence suggests that Latina women in the perinatal period (pregnant and up to one year postpartum) in the United States of America tend to have a higher risk and incidence of perinatal mood and anxiety disorders than White women, and a higher risk and …

Extracurricular Involvement And Anxiety In Relation To Suicide Ideation Among College Students, Paula Floyd

Mahurin Honors College Capstone Experience/Thesis Projects

Little research exists on college students’ extracurricular involvement as it relates to anxiety and suicidal ideation. The current study seeks to examine the relationships between extracurricular involvement, anxiety, and suicidal ideation. First, it was hypothesized that increased extracurricular involvement would relate to increased anxiety. Second, increased anxiety was expected to mediate the relationship between involvement and explicit suicidal ideation. Third, increased anxiety was expected to mediate the relationship between involvement and implicit suicidal ideation. Fourth, it was expected that thwarted belongingness would be a more accurate predictor of suicidal ideation than perceived burdensomeness. The sample included 80 undergraduates with a …

The Perceived Invalidation Of Emotion Scale (Pies): Development And Psychometric Properties, Melissa Jean Zielinski

Graduate Theses and Dissertations

Despite the decades that have passed since invalidation was first theorized to causally influence the development of psychopathology (Linehan, 1993), no measures have been designed and statistically validated to index current emotion invalidation. Research on invalidation has thus grown slowly and often used measures that were designed to assess other constructs (e.g., criticism, abuse) or that retrospectively assess childhood invalidation. This series of five studies describes the development and psychometric evaluation of the Perceived Invalidation of Emotion Scale (PIES), a novel measure of emotion invalidation. Items for the PIES were developed using themes from a qualitative investigation of adults’ experiences …

The Associations Among Expressed Emotion, Relationship Satisfaction, Ptsd Symptoms, Alcohol Use, And Depression: A Longitudinal Investigation With A Military Sample, Laci Lee Zawilinski

Dissertations

PTSD in military personnel is highly prevalent and accompanied by elevated rates of additional issues such as depression, problematic alcohol use, and interpersonal relationship problems. Family members and spouses of military personnel have also been shown to be negatively impacted by PTSD symptoms. Previous research has indicated that family members and spouses’ expressed emotion regarding the PTSD patients’ symptoms negatively impacts treatment outcome in civilian populations. However, studies have yet to investigate the effect of expressed emotion on the course of PTSD symptoms and associated problems in military personnel. Therefore, the purpose of the present investigation was to examine the …