Mental and Social Health Commons^™

Acceptance And Commitment Therapy With Huntington's Disease: A Narrative Review And Case Report Of A Caregiver-Assisted Intervention, Simone H. Schriger, Chelsi N. Nurse, C. Virginia O'Hayer

Department of Psychiatry and Human Behavior Faculty Papers

Acceptance and commitment therapy (ACT) is an experiential, action-oriented talk therapy that emphasizes acceptance of painful inner experience through increased psychological flexibility. In this narrative review and case report, we first review the extant literature on applications of ACT to patients with a variety of mental and physical health challenges, including neurodegenerative disorders, and their caregivers. We then discuss applications of ACT to Huntington's disease (HD). We provide a case report of a 52-year-old man living with HD who, accompanied by his caregiver, received a virtually-delivered 6-session ACT intervention. We measured the patient's self-reported symptoms of depression (PHQ-9) and anxiety …

Legacy Of The Voices Project: Pausing For, Listening To, And Sharing Patient Narratives, Ryan N. Heine, Gheri Terry, Aditya H. Gaur

Journal of Patient-Centered Research and Reviews

In today’s information-overloaded and fast-paced world, it is imperative that healthcare providers, including clinical care and research teams, “Pause” for, “Listen” to, and “Share” what their patients and research participants have to say. The VOICES Project at St. Jude Children's Research Hospital offers that opportunity and is creating an everlasting, powerful legacy – one that could meaningfully change the healthcare and clinical research landscape.

Social Jetlag Alters Markers Of Exercise-Induced Mitochondrial Adaptations In The Heart, Michael B. Dial, Elias M. Malek, Austin R. Cooper, Greco A. Neblina, Nikoleta I. Vasileva, Graham Mcginnis

Kinesiology and Nutrition Sciences Faculty Research

Social jetlag (SJL) represents the behavioral misalignment of sleep and wake times on work days and free days, and potently disrupts the circadian rhythm. SJL affects up to 70% of the population worldwide and is associated with increased risk for many cardiometabolic diseases. Animal models of acute SJL have shown disruption in locomotor activity and expression of clock genes in select tissues, its impact on the heart remains unclear. The purpose of this study was to investigate the effects of prolonged SJL (6 weeks), on activity rhythms, and the impact on exercise-induced adaptations in the heart. Male mice (n …

Contemporary Views Of Spiritual And Theological Reflection (2013-2023) Compared To Forty Years Ago: Analysis Of 32 Texts, Chris Brouillard-Coyle, Des Mcenaney, Joselin Zak, Thomas St. James O’Connor

Consensus

What are contemporary views on spiritual and theological reflection? We answer this question using a hermeneutical research method analyzing 32 texts from the current situation. The data indicate five themes: 1) experiences as sources for spiritual/theological reflection, 2) meaning making as key component for spiritual/theological reflection, 3) growth in spiritual reflection and overlap with theological reflection, 4. some flexible methods; many without explicit method, and 5) spiritual but not religious. Discussion, limitations, and areas for future research are provided.

Infertility Stigma And Openness With Others Are Related To Depressive Symptoms And Meaning In Life In Men And Women Diagnosed With Infertility, Brennan Peterson, Orit Taubman‑Ben‑Ari, Bonnie Chiu, Douglas Brown, David A. Frederick

Psychology Faculty Articles and Research

Background

Stigma is the experience of feeling different from socially accepted norms which can lead to personal devaluation or fear of disapproval from others. For men and women experiencing infertility, stigma has been associated with psychological distress, feelings of otherness in relation to people with children, and selective disclosure with others about their infertility challenges. However, there are few studies which examine how infertility stigma and being open with others are related to depressive symptoms and meaning in life for men and women diagnosed with infertility.

Methods

Participants experiencing infertility were recruited for this cross-sectional study during November 2023-January 2024 …

The Quic-Sp: A Spanish Language Tool Assessing Unpredictability In Early Life Is Linked To Physical And Mental Health, Sabrina R. Liu, Natasha A. Bailey, Sara Romero-González, Amy Moors, Belinda Campos, Elysia P. Davis, Laura M. Glynn

Psychology Faculty Articles and Research

Accumulating evidence indicates that unpredictable signals in early life represent a unique form of adverse childhood experiences (ACEs) associated with disrupted neurodevelopmental trajectories in children and adolescents. The Questionnaire of Unpredictability in Childhood (QUIC) was developed to assess early life unpredictability, encompassing social, emotional, and physical unpredictability in a child’s environment, and has been validated in three independent cohorts. However, the importance of identifying ACEs in diverse populations, including non-English speaking groups, necessitates translation of the QUIC. The current study aims to translate and validate a Spanish language version of the QUIC (QUIC-SP) and assess its associations with mental and …

A Half Century Of Criminalizing Serious Mental Illness: Observations And Considerations, Arthur J. Lurigio

DePaul Journal of Health Care Law

This article describes the difficulties of working with people with serious mental illnesses (PSMIs) at every stage of the criminal justice process—from arrest to post- incarceration release from prison. The needs of PSMI for mental health and social services are complex and require different case management plans and strategies at various points in the process. Severe mental illnesses (SMIs), such as schizophrenia, major depression, and bipolar disorder, stem from abnormalities in the brain structure and neuroprocessing that cause significant distress and dysfunction. People with serious mental illnesses typically suffer from a variety of other related problems (e.g., addiction) that can …

Mental Health Courts: Is There Any Hope For Mental Illness In An Outdated Criminal Justice System?, Brock Imel

DePaul Journal of Health Care Law

Mental health awareness is an ever-growing field of study that has garnered more attention in America after the COVID-19 pandemic. As far back as colonial America, mental illness was considered taboo in society and often reprimanded with punishable crimes. This article seeks to divulge into the history of mental health and its relation to the law, as well as how the creation of mental health courts has led to a decrease in recidivism.

This article aims to provide the reader with an understanding of the evolving field of mental health courts and provide state legislatures foundational knowledge for creating and …

Mental Health In Preprofessional And Professional Circus Artists: A Narrative Review, Melanie I. Stuckey, Stephanie Greenspan, Joanna Nicholas, Veronique Richard, Janine H. Stubbe, Fleur E.C.A. Van Rens

Research outputs 2022 to 2026

Mental health has received little attention in preprofessional and professional circus despite the performance demands, cognitive skill, and emotional labor required. This review aimed to consolidate the literature, identify research gaps, and guide practice priorities for mental health in preprofessional and professional circus artists. A narrative review of the literature was conducted based on the International Olympic Committee’s 2019 consensus statement for mental health in elite athletes. Articles reported on mental health symptoms and disorders (n = 13) and interventions (n = 3) in preprofessional and professional circus contexts. Circus artists may experience more symptoms of depression, anxiety, fatigue, and …

Fos Expression In The Periaqueductal Gray, But Not The Ventromedial Hypothalamus, Is Correlated With Psychosocial Stress-Induced Cocaine-Seeking Behavior In Rats, Nicole M Hinds, Ireneusz D Wojtas, Desta M Pulley, Stephany J Mcdonald, Colton D Spencer, Milena Sudarikov, Nicole E Hubbard, Colin M Kulick-Soper, Samantha De Guzman, Sara Hayden, Jessica J Debski, Bianca Patel, Douglas P Fox, Daniel F Manvich

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Psychosocial stressors are known to promote cocaine craving and relapse in humans but are infrequently employed in preclinical relapse models. Consequently, the underlying neural circuitry by which these stressors drive cocaine seeking has not been thoroughly explored. Using Fos expression analyses, we sought to examine whether the ventromedial hypothalamus (VMH) or periaqueductal gray (PAG), two critical components of the brain's hypothalamic defense system, are activated during psychosocial stress-induced cocaine seeking. Adult male and female rats self-administered cocaine (0.5 mg/kg/inf IV, fixed-ratio 1 schedule, 2 h/session) over 20 sessions. On sessions 11, 14, 17, and 20, a tactile cue was present …

The Benefit Of Green And Blue, Maddie Fitzgerald

D.U.Quark

No abstract provided.

Case Report On Endocrine Induced Paralysis - " Unraveling The Impact Of Thyrotoxicosis On Potassium Homeostasis.", Srujith Pullipudi, Basava Chethan, Srinath K. M, Savitha Vijayakumar, Meghna B.S.

Digital Journal of Clinical Medicine

Thyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism, marked by episodes of muscle weakness and hypokalaemia. Although it predominantly affects young Asian men, it can also occur in females and individuals from non-Asian ethnic groups. TPP is a treatable form of hypokalaemic periodic paralysis and can often be the first indication of thyrotoxicosis. Triggers such as a high-carbohydrate diet, strenuous exercise, emotional stress, and steroid use can provoke TPP attacks. During an acute episode, the key diagnostic indicators are hypokalaemia along with elevated levels of thyroxine (T4) and triiodothyronine (T3). Treatment consists of two phases: promptly correcting hypokalaemia …

Are Maternal Adverse Childhood Experiences (Aces) And Resilience Associated With Breastfeeding Rates And Neonatal Growth?, Lily Zheng, Krystal Hunter, Hsiao-Wei M. Banks, Leslie Abraham, Alla Kushnir

Cooper Rowan Medical Journal

Background: Adverse childhood experiences (ACEs) have shown to have a negative impact on health outcomes. There is evidence of how negative childhood events adversely affect self-esteem in adulthood. Not only do ACEs have an impact on one's own life, but maternal ACEs have shown to have consequences on infants’ development as well, indicating a negative intergenerational impact.

Objectives: To analyze the relationship between maternal ACEs on infant outcomes, breastfeeding adherence, and maternal self-perception

Design/Methods: Between 2020 and 2023, 120 mother-infant pairs from a New Jersey urban hospital were approached between their 2nd trimester and the 2-month well …

Successful Application Of Craniosacral Therapy In A Case Of Self-Harming And Low Mood In A 13-Year-Old Female., Caro O’Neill, Angie Butterfield

Journal of Transformative Touch

This case reports on the effectiveness of CranioSacral Therapy (CST) for a 13-year-old female presenting with self-harming by cutting, self-starving and poor sleep. Seven treatments of 45 minutes each, over a period of 9 months between September 2023 and June 2024 took place and monthly treatments are still ongoing. An improvement in symptoms was recorded after the first treatment and over the period of the treatments the client did not self-harm or self-starve and her sleep improved. At the first session the client scored 24 with the Patient Health Questionnaire – 9 (PHQ-9); at the seventh session her score was …

Feasibility And Acceptability Of The Mazi Umntanakho Digital Tool In South African Settings: A Qualitative Evaluation, Catherine E. Draper, Caylee J. Cook, Elizabeth A. Ankrah, Jesus A. Beltran, Franceli L. Cibrian, Kimberley D. Lakes, Hanna Mofid, Lucretia Williams, Gillian R. Hayes

Engineering Faculty Articles and Research

To address the need for interventions targeting social emotional development and mental health of young children in South Africa, the Mazi Umntanakho (‘know your child’) digital tool was co-designed, and piloted with caregivers and 3–5-year-old children involved in home visiting programmes promoting early childhood development. The aim of this study was to qualitatively evaluate the feasibility and acceptability of this tool in four urban and four rural low-income communities, from the perspective of home visitors and caregivers. Focus groups were conducted with home visitors (n = 117) and caregivers (n = 72). Issues relating to the feasibility of …

Perceived Stress And Coping Mechanisms Observed In Professional Master’S Athletic Training Students, Emily Madrak, Jennifer L. Volberding, Emily Madrak

Internet Journal of Allied Health Sciences and Practice

Purpose: With the shift in level of athletic training education, studies regarding undergraduate students, especially regarding stress and coping, are quickly becoming obsolete. Because of this shift, we sought to investigate level of perceived stress (PS) in professional master’s athletic training (PMAT) students, coping skills used to mitigate PS, and what coping skills form a relationship to alter PS. We observed these variables by gender, age, year in program, and curriculum delivery model. Method: We used a quantitative cross-sectional study online survey to recruit students who were currently enrolled in a Commission on Accreditation of Athletic Training Education (CAATE) accredited …

How Did Covid-19 Impact Physiology Research Globally? – Lessons Learned And Future Recommendations, Jeet Patel, Santanu De

Mako: NSU Undergraduate Student Journal

The Coronavirus Infectious Disease 2019 (COVID-19) pandemic caused massive changes in the medical field across the globe. As the whole world moved from in-person to remote activities, students found themselves in a predicament where they were compelled towards schooling and work online from home. This would mean that all projects, research, tests, and meetings were conducted over Zoom or other online meeting platforms. Laboratories were shut down or only a limited number of people were allowed to enter to conduct the necessary research. This paper discusses how the COVID-19 pandemic affected research process and experiments within various aspects of the …

Parallels Between Internet And Stimulant Drug Addiction, Yashica Bhuvane

Mako: NSU Undergraduate Student Journal

This analysis explores how stimulant addictions—specifically cocaine, methamphetamines, and nicotine—impact the brain's reward system, comparing these effects with those seen in Internet Addiction (IA). Drawing from functional magnetic resonance imaging (fMRI) studies, it assesses changes in key brain regions involved in reward processing, craving, and cognitive control related to these addictive behaviors. The analysis investigates how each stimulant affects dopaminergic transmission and disrupts reward circuitry, highlighting both similarities and differences in brain activation patterns linked to addiction. By comparing these patterns with those seen in IA, the analysis aims to identify which stimulant most closely resembles the neural disruptions associated …

Associations Between Deficit Accumulation Frailty And Baseline Markers Of Lifestyle In The Us Pointer Trial, Mark A Espeland, Yitbarek N Demesie, Kayloni Olson, Samuel N Lockhart, Sarah E Tomaszewski Farias, Maryjo L Cleveland, Christy C Tangney, Lucia Crivelli, Heather M Snyder, Michele K York, Laura D Baker, Rachel A Whitmer, Rena R Wing, Katelyn R Garcia, Kathryn E Callahan

Faculty, Staff and Students Publications

BACKGROUND: Multidomain lifestyle interventions may have the potential to slow biological aging as captured by deficit accumulation frailty indices. We describe the distribution and composition of the 49-component frailty index developed by the U.S. POINTER clinical trial team of investigators and assess its cross-sectional associations with sociodemographic factors and markers chosen to be representative of behaviors targeted by the trial's multidomain interventions.

METHODS: We draw baseline data from the 2 111 volunteers enrolled in U.S. POINTER who were ages 60-79 years and at increased risk for cognitive decline. Frailty components were grouped into 9 domains. Associations that frailty index scores …

Discontiguous Recurrences Of Idh-Wildtype Glioblastoma Share A Common Origin With The Initial Tumor And Are Frequently Hypermutated, Malcolm F Mcdonald, Sricharan Gopakumar, Tareq A Juratli, Ilker Y Eyüpoglu, Ganesh Rao, Jacob J Mandel, Ali Jalali

Faculty, Staff and Students Publications

Glioblastoma is the deadliest primary brain tumor, largely due to inevitable recurrence of the disease after treatment. While most recurrences are local, patients rarely present with a new discontiguous focus of glioblastoma. Little is currently known about the genetic profile of discontiguous recurrences. In our institutional database, we identified 22 patients with targeted exome sequencing of pairs of initial and recurrent IDH-wildtype glioblastoma. Recurrences were classified as contiguous or discontiguous based on the presence or absence of T2 FLAIR signal connection to the initial site of disease on MRI. Exome analysis revealed shared driver and passenger mutations between discontiguous recurrences …