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Articles 1 - 30 of 80
Full-Text Articles in Social and Behavioral Sciences
Learning To Swim: The Act Approach To Living With Depression, Ashley Martinez
Learning To Swim: The Act Approach To Living With Depression, Ashley Martinez
Honors Projects
This illustrated self-help manual was designed as a basis for treatment for individuals of a wide range of ages experiencing depression. The therapeutic base of the manual is Acceptance and Commitment Therapy (ACT), which outlines the pathology of depression as problems in functioning rather than problems in the individual. The ACT theory of depression views problems in functioning as centered around the way negative emotions are perceived and processed through language and problematic actions or inaction as a result of cognitive distortions. Because of problems with language, the manual is illustrated to help the reader understand the foundations of ACT …
An Evaluation Of Mental Health And Methadone: Anxiety, Depression, And Drug Use, Gursimran Khahera
An Evaluation Of Mental Health And Methadone: Anxiety, Depression, And Drug Use, Gursimran Khahera
Master's Projects and Capstones
As a part of the Masters of Science in Behavioral Health field placement, an evaluation was conducted of the integrated treatment plan in mental health and substance abuse at Bay Area Addiction Research and Treatment (BAART) programs. The goal of the BAART programs are to provide comprehensive mental health and substance abuse outpatient recovery services, as well as on-site primary health care services for substance users, mainly opioid use. There is a link between increased substance abuse and increased rates of depression and anxiety. These disorders use the same neuro chemical pathway and are highly codependent upon one another. Because …
Relationships Among Depression, Posttraumatic Stress Disorder, Forgiveness, Meaning In Life, And Spirituality In Survivors Of Intimate Partner Violence, Shannon Marie Rogers
Relationships Among Depression, Posttraumatic Stress Disorder, Forgiveness, Meaning In Life, And Spirituality In Survivors Of Intimate Partner Violence, Shannon Marie Rogers
Doctoral Dissertations
One hundred twenty nine survivors of interpersonal violence completed a paper-and-pencil survey to evaluate depression, PTSD, forgiveness, meaning in life, and spirituality. Five self-report measures were completed including: the Center for Epidemiological Studies-Depression scale, the PTSD Checklist – Stressor Specific version, the Transgression-Related Interpersonal Motivations Inventory, and the Spiritual Involvement and Beliefs Scale. The majority of the participants were female and Caucasian. Significant correlations were found between PTSD and presence of meaning, as well as depression and both presence of and search for meaning. However, hierarchical multiple regressions results indicated that depression and the two meaning in life subscales contributed …
Relationship Quality, Individual Wellbeing, And Gender – A Series Of Longitudinal Studies, Patricia Nola Eugene Roberson
Relationship Quality, Individual Wellbeing, And Gender – A Series Of Longitudinal Studies, Patricia Nola Eugene Roberson
Doctoral Dissertations
Using multiple theories, three studies examined the association between relationship quality, individual wellbeing (e.g., psychological distress), and gender across multiple time points. In Study 1 applied life course theory concepts (e.g., roles, role configurations, role trajectories) and second order latent class analyses were then conducted. Using four relationship role trajectories were identified from these analyses. Relationship role trajectories differed on wellbeing, wherein individuals in stable marriages with higher satisfaction consistently reported greater wellbeing (i.e., lower depression and higher life satisfaction).
Study 2 sought to determine the direction of the association between individual wellbeing and relationship quality. This study specifically examined …
Modeling Hedonic Processing And Anhedonia In Depression, Kevin Mercado
Modeling Hedonic Processing And Anhedonia In Depression, Kevin Mercado
Honors College Theses
Depression is characterized by low positive emotion and a lack of pleasurable experiences, or anhedonia. Past studies have emphasized controlling negative affect, but there is an emerging trend in the depression literature to focus on positive emotion. The current study employed several psychophysiological tools, postauricular reflex, startle blink reflex, and event-related potential (ERP) components such as P3 and the late positive potential (LPP), to assess the dissociable components in positive emotion (consummatory and anticipatory processes). In addition, several different hypotheses of emotional dysfunction were evaluated to accurately model deficits in positive emotionality. A majority of the psychophysiological tools used supported …
Specific Trauma Subtypes Improve The Predictive Validity Of The Harvard Trauma Questionnaire In Iraqi Refugees, Bengt B. Arnetz, Carissa L. Broadbridge, Hikmet Jamil, Mark A. Lumley, Nnamdi Pole, Evone Barkho, Monty Fakhouri, Yousif Rofa Talia, Judith E. Arnetz
Specific Trauma Subtypes Improve The Predictive Validity Of The Harvard Trauma Questionnaire In Iraqi Refugees, Bengt B. Arnetz, Carissa L. Broadbridge, Hikmet Jamil, Mark A. Lumley, Nnamdi Pole, Evone Barkho, Monty Fakhouri, Yousif Rofa Talia, Judith E. Arnetz
Psychology: Faculty Publications
Trauma exposure contributes to poor mental health among refugees, and exposure often is measured using a cumulative index of items from the Harvard Trauma Questionnaire (HTQ). Few studies, however, have asked whether trauma subtypes derived from the HTQ could be superior to this cumulative index in predicting mental health outcomes. A community sample of recently arrived Iraqi refugees (N = 298) completed the HTQ and measures of posttraumatic stress disorder (PTSD) and depression symptoms. Principal components analysis of HTQ items revealed a 5-component subtype model of trauma that accounted for more item variance than a 1-component solution. These trauma subtypes …
The Impact Of Physical Activity On Depressed Mood In Older Seventh-Day Adventists, Benjamin J. Silber
The Impact Of Physical Activity On Depressed Mood In Older Seventh-Day Adventists, Benjamin J. Silber
Loma Linda University Electronic Theses, Dissertations & Projects
Research has shown physical activity (PA) to result in a reduction in depressed mood. The effects have been examined for different age groups, however, it is unclear whether PA effects differ in older adults. A prospective cohort study (N = 6,463) examined duration and intensity of PA in relation to mood in the Biopsychosocial Religion and Health Study (BRHS). Depressed mood indices were expected to be predicted by lower levels of PA and individuals in younger age groups were expected to receive a greater reduction in depressed mood after PA than those in older age groups. Previous PA (minutes of …
Collaborative Treatment Of Late-Life Depression In Primary Care (Germanimpact): Study Protocol Of A Cluster-Randomized Controlled Trial, Iris Wernher, Frederike Bjerregaard, Iris Tinsel, Christiane Bleich, Sigrid Boczor, Thomas Kloppe, Martin Scherer, Martin Härter, Wilhelm Niebling, Hans-Helmut König, Michael Hüll
Collaborative Treatment Of Late-Life Depression In Primary Care (Germanimpact): Study Protocol Of A Cluster-Randomized Controlled Trial, Iris Wernher, Frederike Bjerregaard, Iris Tinsel, Christiane Bleich, Sigrid Boczor, Thomas Kloppe, Martin Scherer, Martin Härter, Wilhelm Niebling, Hans-Helmut König, Michael Hüll
Institute on Aging Publications
Background: Depression is not a normal side effect of aging, however it is one of the most prevalent mental health issues in later life, imposing a tremendous burden on patients, their families, and the healthcare system. We describe the experimental implementation of a collaborative, stepped-care model for the treatment of late-life depression (GermanIMPACT trial) in the German primary care context. GermanIMPACT was developed as an adaptation of a successful and widely used American model. The aim of the study is to evaluate the model’s applicability to the German primary care setting and its cost-effectiveness.
Methods/Design: The study will be conducted …
Testosterone, Dominance, And Depression In Recently Married Couples, Gabriela I. Quiñones-Torres
Testosterone, Dominance, And Depression In Recently Married Couples, Gabriela I. Quiñones-Torres
Masters Theses
Dominance refers to the wide set of behaviors individuals engage in with the intention of achieving or maintaining social status. Considering the relevance of these behaviors in the dynamics of close relationships, this study examined relations among testosterone, dominance, and the emotional health of a total of 225 opposite sex newlywed couples. An original measure of dominance was developed that accounted for both positive and negative manifestations, as well as situational and dispositional qualities of these status-promoting behaviors. Structural equation analyses revealed that dominance behaviors predict depression for both wives and husbands, and that positive and negative aspects of dominance …
The Link Between Insecure Attachment And Depression: Two Potential Pathways, Cassandra C. Devito
The Link Between Insecure Attachment And Depression: Two Potential Pathways, Cassandra C. Devito
Masters Theses
A wealth of research demonstrates a strong link between insecure attachment and depressive symptoms. However, thus far no work has discerned different pathways to depression for each of the insecure subtypes: anxious and avoidant attachment. This work looks at the behaviors that couples engage in during a conflict interaction as a potential mediator for the attachment-depression relationship, with different behaviors mediating the link between anxious and avoidant attachment and depression. For anxiously attached individuals, it was predicted that lack of support and response from the partner (actual or perceived) would account for the relationship between their attachment and depressive symptoms. …
Parenting Dimensions And Internalizing Symptoms Among Low-Income Latino Adolescents: Cultural Values As Moderators, Crystalia Sulaiman
Parenting Dimensions And Internalizing Symptoms Among Low-Income Latino Adolescents: Cultural Values As Moderators, Crystalia Sulaiman
College of Science and Health Theses and Dissertations
Among ethnic minority youth, Latino adolescents disproportionately report higher levels of depression and anxiety than their peers of other ethnic backgrounds. The purpose of the present study is to better understand the familial and sociocultural factors that impact mental health among Latino adolescents. Specifically, the present study examines how youth cultural values (i.e., family obligation and affiliative obedience) moderate the relation between parenting dimensions (i.e., parental acceptance and parental psychological control) and youth internalizing symptoms (i.e., depression and anxiety) cross-sectionally and longitudinally. Latino adolescents (n = 115) from a Chicago public school categorized as "lowincome" participated in a survey and …
Behavioral Activation For Depressed Breast Cancer Patients: The Impact Of Therapeutic Compliance And Quantity Of Activities Completed On Symptom Reduction, Marlena Maria Ryba
Behavioral Activation For Depressed Breast Cancer Patients: The Impact Of Therapeutic Compliance And Quantity Of Activities Completed On Symptom Reduction, Marlena Maria Ryba
Doctoral Dissertations
Behavioral activation (BA) is an empirically validated treatment that reduces depression by increasing overt behaviors and exposure to reinforcing environmental contingencies. Although research has identified an inverse correlation between pleasant or rewarding activities and depression, the causal relation between increased structured activities and reduced depression has not directly been studied. In the context of a recent randomized trial (Hopko et al., 2011), this study used longitudinal data and growth curve modeling to examine relationships among the quantity of activities completed, proportion of activities completed (i.e., therapeutic compliance), environmental reward, and depression in breast cancer patients treated with BATD (n …
Mental Health Referral In Primary Care: Influence Of A Screening Instrument And A Brief Educational Intervention, Michael T. Miesner
Mental Health Referral In Primary Care: Influence Of A Screening Instrument And A Brief Educational Intervention, Michael T. Miesner
Electronic Theses and Dissertations
Although less than half of all patients with mental disorders seek mental health treatment per se, approximately 80% of all people will visit their primary care physician (PCPs) within a year (Strosahl, 1998). However, it is not well understood how to best handle patients presenting with mental health issues in primary care practices. The purpose of this project was to implement an intervention involving a screening measure for anxiety and mood disorders in a primary care setting to increase the volume of anxiety and mood disorder screening, to increase the accuracy of disorder detection, and to also enhance PCPs patterns …
Equity Of Social Support And Its Relationship With Depression, Anxiety, And Antiretroviral Medication Adherence Among Seroconcordant Dyads Of Hiv-Positive African Americans And Their Informal Supporters, Angela Roethel Wendorf
Equity Of Social Support And Its Relationship With Depression, Anxiety, And Antiretroviral Medication Adherence Among Seroconcordant Dyads Of Hiv-Positive African Americans And Their Informal Supporters, Angela Roethel Wendorf
Theses and Dissertations
Social support may be an important resource for those coping with stigmatized chronic illnesses, such as HIV/AIDS, as social support may buffer the deleterious impact of HIV-related distress (Derlega, Winstread, Oldfield, & Barbee, 2003; Stutterheim, Bos, Pryor, Brands, Liebregts, & Schaalma, 2011; Ueno & Adams, 2001). Yet little is known about characteristics of social support among HIV-positive patients in relationships with other HIV-positive individuals and whether there is an equivalent perception and provision of support between each patient in the relationship. To examine how equity of support within the dyad may contribute to nuances in social support, mental health outcomes, …
Addressing Self-Reported Depression, Anxiety, And Stress In College Students Via Web-Based Self-Compassionate Journaling, Jessica Rose Williamson
Addressing Self-Reported Depression, Anxiety, And Stress In College Students Via Web-Based Self-Compassionate Journaling, Jessica Rose Williamson
Electronic Theses and Dissertations
Depression, anxiety, and stress in the college undergraduate population have been steadily rising over the past decade. Trait self-compassion has been shown to be significantly and negatively related to perceptions of stress and symptoms of depression and anxiety. Research has indicated that self-compassion inductions are effective in increasing state self-compassion. In general, selfcompassion inductions are designed to be easily self-administered. Current research on Internetbased interventions indicates that self-administered therapeutic techniques are effective in reducing self-reported depression, anxiety, and stress. The goal of the current study was to compare the effects of self-compassionate journaling, narrative journaling, and a true control group …
An Examination Of The Relationship Between Levels Of Food Security And Depression, Erica K. Svojse
An Examination Of The Relationship Between Levels Of Food Security And Depression, Erica K. Svojse
Theses and Dissertations
Prior research has identified a variety of common correlates between food security and depression but oftentimes the data used in these analyses are not representative of the US or do not consider multiple categorical levels of the focal variables. Using data from the 2009-2010 National Health and Nutrition Examination (NHANES), this study sought to examine the relationship between four levels of food security - full, marginal, low and very low - and depression. The findings indicate low and very low food security are significantly related to an increased risk of depression, while marginal food security is not significantly different from …
Internalized Oppression, Restricted Affection, And Psychological Distress In Asian And Latino Men Who Have Sex With Men, Nicholas S. Bishop
Internalized Oppression, Restricted Affection, And Psychological Distress In Asian And Latino Men Who Have Sex With Men, Nicholas S. Bishop
Masters Theses
Research on internalized oppression in intersecting identities remains vitally important for the mental health of minority individuals. This study investigates the mediating effect of restriction of affectionate behavior on the relationship between multiple oppressions (i.e, internalized racism, internalized heterosexism, and internalized sexism) and psychological distress in 172 Asian (n = 57) and Latino (n = 115) men who have sex with men. Data were collected using online snowball sampling via Facebook and listservs. Findings revealed that internalized racism and internalized heterosexism were related to psychological distress, and that restrictive affectionate behaviors with other men fully mediated these relationships. That is, …
Serotonin Transporter Genotype Modulates Hpa Axis Output During Stress: Effect Of Stress, Dexamethasone Test And Acth Challenge, Andrea N. Sorenson, Erin C. Sullivan, Sally P. Mendoza, John P. Capitanio, James Dee Higley
Serotonin Transporter Genotype Modulates Hpa Axis Output During Stress: Effect Of Stress, Dexamethasone Test And Acth Challenge, Andrea N. Sorenson, Erin C. Sullivan, Sally P. Mendoza, John P. Capitanio, James Dee Higley
Faculty Publications
Background—Studies show that the hypothalamic–pituitary–adrenal (HPA) axis is dysregulated in depression. Some studies suggest that variation in the serotonin transporter genotype (hereafter 5HTT) modulates both risk for depression and psychopathological HPA axis responsiveness. Rhesus monkeys are well suited to model such relationships. Rhesus macaque models of human psychopathology have assessed the effect of the serotonin transporter (rh5HTT) on levels of cortisol in stressed subjects. These studies show that that under conditions of stress, heterozygous females (Ls) reared under adversity exhibit high levels of cortisol. Studies have not to our knowledge, however, assessed the potential additive effect on the cortisol response …
Serotonin Transporter Genotype Modulates Hpa Axis Output During Stress: Effect Of Stress, Dexamethasone Test And Acth Challenge, Andrea N. Sorenson, Erin C. Sullivan, Sally P. Mendoza, John P. Capitanio, James Dee Higley
Serotonin Transporter Genotype Modulates Hpa Axis Output During Stress: Effect Of Stress, Dexamethasone Test And Acth Challenge, Andrea N. Sorenson, Erin C. Sullivan, Sally P. Mendoza, John P. Capitanio, James Dee Higley
Faculty Publications
Background—Studies show that the hypothalamic–pituitary–adrenal (HPA) axis is dysregulated in depression. Some studies suggest that variation in the serotonin transporter genotype (hereafter 5HTT) modulates both risk for depression and psychopathological HPA axis responsiveness. Rhesus monkeys are well suited to model such relationships. Rhesus macaque models of human psychopathology have assessed the effect of the serotonin transporter (rh5HTT) on levels of cortisol in stressed subjects. These studies show that that under conditions of stress, heterozygous females (Ls) reared under adversity exhibit high levels of cortisol. Studies have not to our knowledge, however, assessed the potential additive effect on the cortisol response …
The Relation Of Anxiety, Depression, And Stress To Binge Eating Behavior, Diane L. Rosenbaum
The Relation Of Anxiety, Depression, And Stress To Binge Eating Behavior, Diane L. Rosenbaum
Dissertations
Binge eating is an impairing and prevalent problem. Theories of binge eating suggest negative affect is of primary importance in the development and maintenance of binge eating behavior. To date, investigations of binge eating have often examined depression, however relatively little is known about other psychological factors. The current study aimed to extend the literature by examining several psychological factors in relation to binge eating behavior. Specifically, the relation between binge eating behavior and three psychological factors, depression, anxiety and stress, were examined. Data were collected via online surveys from a community sample of men and women of diverse backgrounds. …
Hispanic Residential Ethnic Density And Depression In Post-Acute Coronary Syndrome Patients: Re-Thinking The Role Of Social Support, Ellen-Ge Denton, Jonathan A. Shaffer, Carmela Alcantra, Lynn Clemow, Elizabeth Denton
Hispanic Residential Ethnic Density And Depression In Post-Acute Coronary Syndrome Patients: Re-Thinking The Role Of Social Support, Ellen-Ge Denton, Jonathan A. Shaffer, Carmela Alcantra, Lynn Clemow, Elizabeth Denton
Publications and Research
Background: The ethnic density hypothesis suggests that ethnic density confers greater social support and consequently protects against depressive symptoms in ethnic minority individuals. However, the potential benefits of ethnic density have not been examined in individuals who are facing a specific and salient life stressor.
Aims: We examined the degree to which the effects of Hispanic ethnic density on depressive symptoms are explained by socioeconomic resources and social support.
Methods: Patients with acute coronary syndrome (ACS, N = 472) completed the Beck Depression Inventory (BDI) and measures of demographics, ACS clinical factors and perceived social support. Neighborhood characteristics, including median …
Respite Care, Stress, Uplifts, And Depression In Single Mothers Of Children With Autism Spectrum Disorders, Ruthann Grawe Christensen
Respite Care, Stress, Uplifts, And Depression In Single Mothers Of Children With Autism Spectrum Disorders, Ruthann Grawe Christensen
Theses and Dissertations
Single mothers of children with autism spectrum disorders (ASD) are likely to experience high levels of stress and be at risk for depression. However, respite care can reduce parenting stress and lower psychological distress in parents of children with disabilities. This study focused on single mothers of children with ASD and their reports of stress relative to respite care received. One hundred and twenty-two single mothers completed the Respite Care Instrument, Center for Epidemiological Studies Depression Scale, Hassles and Uplifts Scale, and Caregiver Burden Instrument. Results were mixed. Respite care was positively related to daily uplifts, but not significantly related …
Changing The Course Of Comorbid Eating Disorders And Depression: What Is The Role Of Public Health Interventions In Targeting Shared Risk Factors?, Carolyn Becker, Maribel Plasencia, Lisa Smith Kilpela, Morgan Briggs, Tiffany Stewart
Changing The Course Of Comorbid Eating Disorders And Depression: What Is The Role Of Public Health Interventions In Targeting Shared Risk Factors?, Carolyn Becker, Maribel Plasencia, Lisa Smith Kilpela, Morgan Briggs, Tiffany Stewart
Carolyn Becker
Public health has a productive history of improving global health due to its focus on reaching large populations using effective and scalable interventions. Yet, the marriage between evidence-based science and the implementation of community/public health interventions within mental illness remains underdeveloped. Research suggests that major depression is the most commonly cited comorbidity for eating disorders (EDs). Thus, identification of public health strategies that jointly impact depression and EDs, including shared risk factors, has the potential to significantly impact mental health suffering. The primary aim of this paper is to examine and discuss such public health approaches as well as explore …
Associations Between Hypothalamic-Pituitary-Adrenal Axis System Gene Variants And Cortisol Reactivity In Preschoolers: Main Effects And Gene-Environment Interactions, Haroon I. Sheikh
Electronic Thesis and Dissertation Repository
Exposure to stressful events during early development has consistently been shown to produce long lasting effects on the hypothalamic-pituitary-adrenal (HPA) axis, which may increase vulnerability to mood and anxiety disorders. Recently reported genetic association studies indicate that these disorders may be influenced, in part, by gene-environment interactions (GxE) involving polymorphisms within the corticotrophin-releasing hormone and monoaminergic system genes. However, little is known about how genetic variants and life stress work to shape children’s neuroendocrine reactivity and emerging symptoms. Therefore, the aim of this thesis is to examine main effects of candidate genes and GxE on the neuroendocrine stress response and …
Internalizing Disorders In Early Childhood: Professional Development Framework For Teachers, Danielle Guttman
Internalizing Disorders In Early Childhood: Professional Development Framework For Teachers, Danielle Guttman
Dissertations, Theses, and Capstone Projects
Recent research indicates that internalizing disorders such as depression, anxiety, and posttraumatic stress disorder (PTSD) manifest in young children. Since early childhood teachers spend a substantial portion of their day with young children, it is important to examine their beliefs and behaviors surrounding these disorders. The role of the school psychologist has come to include providing support for educators such as presenting up-to-date research through professional development (PD). The current investigation implemented an intervention designed to compare different forms of PD seminars ("Information" and "Strategies") designed to increase teachers' awareness of internalizing disorders in early childhood. Ninety-nine participants comprised the …
Testing A Model Of Maladaptive Perfectionism And Depression Symptoms: The Roles Of Emotional Disclosure, Emotion Regulation Strategies, Adult Attachment, And Shame, Angela M. Garrison
Testing A Model Of Maladaptive Perfectionism And Depression Symptoms: The Roles Of Emotional Disclosure, Emotion Regulation Strategies, Adult Attachment, And Shame, Angela M. Garrison
Dissertations
Previous research has supported a link between maladaptive perfectionism and higher levels of depression symptoms. However, researchers have not yet investigated the ways in which emotion regulation processes may mediate this relationship. Therefore, the primary purpose of this study was to evaluate emotional disclosure, emotional avoidance, and rumination as mediators of the relation between maladaptive perfectionism and depression symptoms. Additionally, this study also investigated the role that insecure attachment orientations play in the relationship between maladaptive perfectionism and use of particular emotion regulation strategies. Further, the role of shame in the emotion regulation processes of individuals with higher levels of …
Mood And Experience: Effects Of Ostracism On Diathesis Activation, Rachel Archer
Mood And Experience: Effects Of Ostracism On Diathesis Activation, Rachel Archer
Mahurin Honors College Capstone Experience/Thesis Projects
The stress-diathesis model is a well-known but little-tested theory which states that people can possess diatheses, or vulnerabilities, to certain mental disorders such as depression or anxiety. These diatheses are activated when a person is under stress. This study examined how ostracism as a temporary stressor can trigger existing diatheses and cause increases in depression symptoms among at-risk people. Theory suggests that ostracism is likely to trigger symptoms of depression in at-risk people. This study is an extension of a study conducted by Luxton, Ingram, and Wenzlaff (2006) in which people with naturally varying levels of diathesis factors were exposed …
A Mental Health Epidemic: The Case For Mental Health Programs On College Campuses And How To Increase Awareness, Connor Deason
A Mental Health Epidemic: The Case For Mental Health Programs On College Campuses And How To Increase Awareness, Connor Deason
Senior Theses
This senior thesis project focused on the problem of mental health on college campuses. Specific interest was placed on students at the University of South Carolina. In the end, the goal was to create a product that could be used by the Counseling and Human Development Center to help increase the use of student mental health services and reduce levels of stigma surrounding mental health problems. In talking with staff members of the Counseling and Human Development Center, staff members shared a desire for a video that would advertise the services of the Counseling Center. Thus, the true purpose of …
The Reversal Effects Of Curcumin, An Herbal Remedy, On The Impairments Induced By Vmat-2 Inhibitor Tetrabenazine, Emily Qian, Samantha E. Yohn
The Reversal Effects Of Curcumin, An Herbal Remedy, On The Impairments Induced By Vmat-2 Inhibitor Tetrabenazine, Emily Qian, Samantha E. Yohn
Honors Scholar Theses
Substantial evidence has shown that dopamine (DA), particularly in the nucleus accumbens (NAc), is involved in behavioral activation and effort-related processes, such as overcoming work related response costs. Interference with accumbens DA transmission through administration of the vesicular monoamine transportor-2 (VMAT-2) inhibitor tetrabenazine (TBZ) produces an alteration of response allocation in the concurrent FR5/chow choice procedure, biasing animals toward the lower effort alternative. It has been suggested that these drug-induced shifts in effort-related choice behavior seen in rodents are analogous to symptoms such as psychomotor retardation, anergia, and fatigue, which can be observed in people with depression and other related …
Changing The Course Of Comorbid Eating Disorders And Depression: What Is The Role Of Public Health Interventions In Targeting Shared Risk Factors?, Carolyn Becker, Maribel Plasencia, Lisa S. Kilpela, Morgan Briggs, Tiffany Stewart
Changing The Course Of Comorbid Eating Disorders And Depression: What Is The Role Of Public Health Interventions In Targeting Shared Risk Factors?, Carolyn Becker, Maribel Plasencia, Lisa S. Kilpela, Morgan Briggs, Tiffany Stewart
Psychology Faculty Research
Public health has a productive history of improving global health due to its focus on reaching large populations using effective and scalable interventions. Yet, the marriage between evidence-based science and the implementation of community/public health interventions within mental illness remains underdeveloped. Research suggests that major depression is the most commonly cited comorbidity for eating disorders (EDs). Thus, identification of public health strategies that jointly impact depression and EDs, including shared risk factors, has the potential to significantly impact mental health suffering. The primary aim of this paper is to examine and discuss such public health approaches as well as explore …