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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
The Reversal Effects Of Curcumin, An Herbal Remedy, On The Impairments Induced By Vmat-2 Inhibitor Tetrabenazine, Emily Qian, Samantha E. Yohn
The Reversal Effects Of Curcumin, An Herbal Remedy, On The Impairments Induced By Vmat-2 Inhibitor Tetrabenazine, Emily Qian, Samantha E. Yohn
Honors Scholar Theses
Substantial evidence has shown that dopamine (DA), particularly in the nucleus accumbens (NAc), is involved in behavioral activation and effort-related processes, such as overcoming work related response costs. Interference with accumbens DA transmission through administration of the vesicular monoamine transportor-2 (VMAT-2) inhibitor tetrabenazine (TBZ) produces an alteration of response allocation in the concurrent FR5/chow choice procedure, biasing animals toward the lower effort alternative. It has been suggested that these drug-induced shifts in effort-related choice behavior seen in rodents are analogous to symptoms such as psychomotor retardation, anergia, and fatigue, which can be observed in people with depression and other related …
Development Of A Brief Screening Measure For Depression And Problem Drinking, Chris Wera
Development Of A Brief Screening Measure For Depression And Problem Drinking, Chris Wera
Electronic Theses and Dissertations
This study examined the psychometric characteristics of a brief assessment measure for screening for depression and alcohol use on a college campus prior to primary care medical office visits. The measure was adapted from two widely used measures: the Patient Health Questionnaire (PHQ-4) and the Alcohol Use Disorder Identification Test (AUDIT-C). Impulsivity, which has been associated with both depression and problematic alcohol use, was also examined through additional questions. The research study investigated the psychometric properties of the PHQ-4 and the AUDIT-C, and explored if eight impulsivity items from the UPPS-P measure could enhance screening for depression and problematic alcohol …