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Social and Behavioral Sciences Commons™
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Articles 1 - 6 of 6
Full-Text Articles in Social and Behavioral Sciences
Transcriptional Control Of Kcnq Channel Genes And The Regulation Of Neuronal Excitability, Mariusz Mucha, Lezanne Ooi, John Linley, Pawel Mordaka, Carine Dalle, Brian Robertson, Nikita Gamper, Ian C. Wood
Transcriptional Control Of Kcnq Channel Genes And The Regulation Of Neuronal Excitability, Mariusz Mucha, Lezanne Ooi, John Linley, Pawel Mordaka, Carine Dalle, Brian Robertson, Nikita Gamper, Ian C. Wood
Faculty of Science - Papers (Archive)
Regulation of the resting membrane potential and the repolarization of neurons are important in regulating neuronal excitability. The potassium channel subunits Kv7.2 and Kv7.3 play a key role in stabilizing neuronal activity. Mutations in KCNQ2 and KCNQ3, the genes encoding Kv7.2 and Kv7.3, cause a neonatal form of epilepsy, and activators of these channels have been identified as novel antiepileptics and analgesics. Despite the observations that regulation of these subunits has profound effects on neuronal function, almost nothing is known about the mechanisms responsible for controlling appropriate expression levels. Here we identify two mechanisms responsible for regulating KCNQ2 and …
Effect Of Two Types Of Tree Guards (With And Without Weed Control) On Tree Seedling Establishment, Brenton Ladd, Stephen P. Bonser, Joshua R. Larsen
Effect Of Two Types Of Tree Guards (With And Without Weed Control) On Tree Seedling Establishment, Brenton Ladd, Stephen P. Bonser, Joshua R. Larsen
Faculty of Science - Papers (Archive)
No abstract provided.
Predicting Avian Distributions To Evaluate Spatiotemporal Overlap With Locust Control Operations In Eastern Australia, Judit K. Szabo, Pamela J. Davy, Michael Hooper, Lee Astheimer
Predicting Avian Distributions To Evaluate Spatiotemporal Overlap With Locust Control Operations In Eastern Australia, Judit K. Szabo, Pamela J. Davy, Michael Hooper, Lee Astheimer
Faculty of Science - Papers (Archive)
Locusts and grasshoppers cause considerable economic damage to agriculture worldwide. The Australian Plague Locust Commission uses multiple pesticides to control locusts in eastern Australia. Avian exposure to agricultural pesticides is of conservation concern, especially in the case of rare and threatened species. The aim of this study was to evaluate the probability of pesticide exposure of native avian species during operational locust control based on knowledge of species occurrence in areas and times of application. Using presence-absence data provided by the Birds Australia Atlas for 1998 to 2002, we developed a series of generalized linear models to predict avian occurrences …
Complete Mitochondrial Genome Of The Frillneck Lizard (Chlamydosaurus Kingii, Reptilia; Agamidae), Another Squamate With Two Control Regions, Beata Ujvari, Thomas R. Madsen
Complete Mitochondrial Genome Of The Frillneck Lizard (Chlamydosaurus Kingii, Reptilia; Agamidae), Another Squamate With Two Control Regions, Beata Ujvari, Thomas R. Madsen
Faculty of Science - Papers (Archive)
AbstractUsing PCR, the complete mitochondrial genome was sequenced in three frillneck lizards (Chlamydosaurus kingii).The mitochondria spanned over 16,761 bp. As in other vertebrates, two rRNA genes, 22 tRNA genes and 13 protein codinggenes were identified. However, similar to some other squamate reptiles, two control regions (CRI and CRII) were identified,spanning 801 and 812 bp, respectively. Our results were compared with another Australian member of the family Agamidae,the bearded dragon (Pogana vitticeps). The overall base composition of the light-strand sequence largely mirrored thatobserved in P. vitticeps. Furthermore, similar to P. vitticeps, we observed an insertion 801 bp long between the ND5 …
Vegetation Over Hydrologic Control Of Sediment Transport Over The Past 100,000 Yr, Anthony Dosseto, Simon Turner, P P Hesse, Kate Maher, Kirstie Fryirs
Vegetation Over Hydrologic Control Of Sediment Transport Over The Past 100,000 Yr, Anthony Dosseto, Simon Turner, P P Hesse, Kate Maher, Kirstie Fryirs
Faculty of Science - Papers (Archive)
No abstract provided.
Potential Roles Of Abundant Extracellular Chaperones In The Control Of Amyloid Formation And Toxicity, Mark R. Wilson, Justin J. Yerbury, Stephen Poon
Potential Roles Of Abundant Extracellular Chaperones In The Control Of Amyloid Formation And Toxicity, Mark R. Wilson, Justin J. Yerbury, Stephen Poon
Faculty of Science - Papers (Archive)
The in vivo formation of fibrillar proteinaceous deposits called amyloid is associated with more than 40 serious human diseases, collectively referred to as protein deposition diseases. In many cases the amyloid deposits are extracellular and are found associated with newly identified abundant extracellular chaperones (ECs). Evidence is presented suggesting an important regulatory role for ECs in amyloid formation and disposal in the body. A model is presented which proposes that, under normal conditions, ECs stabilize extracellular misfolded proteins by binding to them, and then guide them to specific cell receptors for uptake and subsequent degradation. Thus ECs and their receptors …