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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
Anxiolytic Effects Of Propranolol And Diphenoxylate On Mice And Automated Stretch-Attend Posture Analysis, Kevin Scott Holly
Anxiolytic Effects Of Propranolol And Diphenoxylate On Mice And Automated Stretch-Attend Posture Analysis, Kevin Scott Holly
Doctoral Dissertations
The prevention of social anxiety, performance anxiety, and social phobia via the combination of two generic drugs, diphenoxylate HC1 (opioid) plus atropine sulfate (anticholinergic) and propranolol HCl (beta blocker) was evaluated in mice through behavioral studies. A patent published on a September 8, 2011 by Benjamin D. Holly, US 2011/0218215 Al, prompted the research. The drug combination of diphenoxylate and atropine plus propranolol could be an immediate treatment for patients suffering from acute phobic and social anxiety disorders. Demonstrating the anxiolytic effects of the treatment on mice would validate a mouse model for neuroscientist to be used to detect the …
Correspondence Between Change In Adult Attachment Patterns And Change In Depression Symptoms In Early Marriage, Cassandra C. Devito
Correspondence Between Change In Adult Attachment Patterns And Change In Depression Symptoms In Early Marriage, Cassandra C. Devito
Doctoral Dissertations
Countless studies have demonstrated the association between attachment styles and depressive symptoms; however, thus far, none have examined concurrent change. That is, does change in attachment style predict change in depressive symptoms over time? This question was examined in a sample of 229 heterosexual newlywed couples from Western Massachusetts. It was found that changes in attachment avoidance in particular predicted changes in depressive and anxious symptoms over time. Being a parent also played a role in participants' overall attachment styles, depressive symptoms and anxious symptoms on average, with differences observed by gender. Implications and suggestions for future research are discussed.