Social and Behavioral Sciences Commons^™

Citalopram Improves Metabolic Risk Factors Among High Hostile Adults: Results Of A Placebo-Controlled Intervention., Thomas W. Karmarck, Matthew F. Muldoon, Stephen B. Manuck, Roger F. Haskett, Jeewon Cheong, Janine D. Flory, Elizabeth Vella

Faculty Publications

Hostility is associated with a number of metabolic risk factors for cardiovascular disease, including waist—hip ratio, glucose, and triglycerides. Along with hostility, many of these measures have also been shown to be associated with reduced central serotonergic function. We have previously reported that a citalopram intervention was successful in reducing hostility by self-report assessment (Kamarck et al., 2009). Here we examine the effects of this serotonergic intervention on metabolic risk factors in the same sample.