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Social and Behavioral Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2003

Theses Digitization Project

Dopamine -- Receptors -- Effect of drugs on

Articles 1 - 2 of 2

Full-Text Articles in Social and Behavioral Sciences

Long-Term Effects Of 3,4- Methylenedioxymethamphetamine (Mdma) On Serotonergic And Dopaminergic Functioning, Jodi Lynn Kohutek Jan 2003

Long-Term Effects Of 3,4- Methylenedioxymethamphetamine (Mdma) On Serotonergic And Dopaminergic Functioning, Jodi Lynn Kohutek

Theses Digitization Project

Methylenedioxymethamphetamine (MDMA) popularly known as "Ecstasy" continues to gain popularity as a recreational drug that has been shown to increase serotonin and dopamine levels. The present study has demonstrated that repeated exposure to MDMA produces long-term damage to serotonergic and dopaminergic neurons in various regions of the rat brain.


Induction And Expression Of Cocaine-Induced Behavioral Sensitization: Modulation By A Partial D₂-Like Agonist, Janet Marie Sibole Jan 2003

Induction And Expression Of Cocaine-Induced Behavioral Sensitization: Modulation By A Partial D₂-Like Agonist, Janet Marie Sibole

Theses Digitization Project

The purpose of this study was to investigate whether a partial D₂-like dopamine agonist (i.e. terguride) would block the induction or expression of cocaine-induced behavioral sensitization in pre-weanling rats. The ability of terguride to induce behavioral sensitization was also examined, as partial D₂-like agonists have agonistic actions in cases of low dopaminergic tone.