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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
Effects Of Repeated Nicotine Vapor Exposure And Withdrawal On Somatic Signs, Anxiety-Like Behavior, And Brain Reward Thresholds In Male Sprague Dawley Rats, Michelle Martinez
Effects Of Repeated Nicotine Vapor Exposure And Withdrawal On Somatic Signs, Anxiety-Like Behavior, And Brain Reward Thresholds In Male Sprague Dawley Rats, Michelle Martinez
Open Access Theses & Dissertations
No abstract provided.
Ketamine Pre-Exposure Does Not Influence Later-Life Responses To Reward-Related Stimuli In Female C57bl/6 Mice, Israel Garcia
Ketamine Pre-Exposure Does Not Influence Later-Life Responses To Reward-Related Stimuli In Female C57bl/6 Mice, Israel Garcia
Open Access Theses & Dissertations
Preclinical work indicates that exposure to traditional antidepressant medications, in adolescent and adult female subjects, alters reward-related behavior later in life. In recent years, the anesthetic ketamine (KET), now used as a fast-acting antidepressant, has shown promising therapeutic efficacy for the management of depression. However, the potential long-term behavioral consequences of KET exposure across development have not been thoroughly assessed. Thus, to address this issue, we examined if KET exposure, during adolescence or early adulthood, results in enduring alterations in responsivity to the rewarding properties of sucrose and cocaine later in life. Specifically, female C57BL/6 mice were randomly assigned to …