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Full-Text Articles in Social and Behavioral Sciences
The Role Of Serotonin In The Estradiol-Dependent Selectivity Of Auditory Regions In Songbirds, Calista J. Henry
The Role Of Serotonin In The Estradiol-Dependent Selectivity Of Auditory Regions In Songbirds, Calista J. Henry
Electronic Thesis and Dissertation Repository
Breeding-typical levels of estradiol in songbirds has been shown to lead to selective auditory processing and induce a release of serotonin in auditory regions of the forebrain. These findings triggered the question of whether auditory discrimination is driven by estradiol directly, or by the associated release of serotonin. I treated non-breeding female white-throated sparrows (Zonotrichia albicollis) with either blank implants, 17β-estradiol, serotonin enhancer and blank implants, or serotonin antagonist and 17β-estradiol implants. Birds then heard male conspecific songs or control tones, and ZENK-immunoreactivity was quantified in the caudomedial nidopallium (NCM) and caudomedial mesopallium (CMM). While I did not …
Associations Between Hypothalamic-Pituitary-Adrenal Axis System Gene Variants And Cortisol Reactivity In Preschoolers: Main Effects And Gene-Environment Interactions, Haroon I. Sheikh
Electronic Thesis and Dissertation Repository
Exposure to stressful events during early development has consistently been shown to produce long lasting effects on the hypothalamic-pituitary-adrenal (HPA) axis, which may increase vulnerability to mood and anxiety disorders. Recently reported genetic association studies indicate that these disorders may be influenced, in part, by gene-environment interactions (GxE) involving polymorphisms within the corticotrophin-releasing hormone and monoaminergic system genes. However, little is known about how genetic variants and life stress work to shape children’s neuroendocrine reactivity and emerging symptoms. Therefore, the aim of this thesis is to examine main effects of candidate genes and GxE on the neuroendocrine stress response and …