Open Access. Powered by Scholars. Published by Universities.®
Social and Behavioral Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Social and Behavioral Sciences
Tests For 2 X 2 Tables In Clinical Trials, Vic Hasselblad, Yulia Lokhnygina
Tests For 2 X 2 Tables In Clinical Trials, Vic Hasselblad, Yulia Lokhnygina
Journal of Modern Applied Statistical Methods
Five standard tests are compared: chi-squared, Fisher's exact, Yates’ correction, Fisher’s exact mid-p, and Barnard’s. Yates’ is always inferior to Fisher’s exact. Fisher’s exact is so conservative that one should look for alternatives. For certain sample sizes, Fisher’s mid-p or Barnard’s test maintain the nominal alpha and have superior power.