Social and Behavioral Sciences Commons^™

Individual Differences In Social Play Behaviour Predict Alcohol Intake And Control Over Alcohol Seeking In Rats, Heidi M. B. Lesscher, E. J. Marijke Achterberg, Stephen M. Siviy, Louk J. M. J. Vanderschuren

Psychology Faculty Publications

Rationale

Social play behaviour is a rewarding social activity displayed by young mammals, thought to be important for the development of brain and behaviour. Indeed, disruptions of social play behaviour in rodents have been associated with cognitive deficits and augmented sensitivity to self-administration of substances of abuse, including alcohol, later in life. However, the relation between social development and loss of control over substance use, a key characteristic of substance use disorders including alcohol use disorder (AUD), has not been investigated. Moreover, it remains unknown how inherent differences in playfulness relate to differences in the sensitivity to substance use and …

The Winding Road To Relapse: Forging A New Understanding Of Cue-Induced Reinstatement Models And Their Associated Neural Mechanisms, Mark D. Namba, Seven E. Tomek, M. Foster Olive, Joshua S. Beckmann, Cassandra D. Gipson

Psychology Faculty Publications

In drug addiction, cues previously associated with drug use can produce craving and frequently trigger the resumption of drug taking in individuals vulnerable to relapse. Environmental stimuli associated with drugs or natural reinforcers can become reliably conditioned to increase behavior that was previously reinforced. In preclinical models of addiction, these cues enhance both drug self-administration and reinstatement of drug seeking. In this review, we will dissociate the roles of conditioned stimuli as reinforcers from their modulatory or discriminative functions in producing drug-seeking behavior. As well, we will examine possible differences in neurobiological encoding underlying these functional differences. Specifically, we will …

Stress Alters The Discriminative Stimulus And Response Rate Effects Of Cocaine Differentially In Lewis And Fischer Inbred Rats, Therese A. Kosten, Mindy Miserendino

Psychology Faculty Publications

Stress enhances the behavioral effects of cocaine, perhaps via hypothalamic-pituitary-adrenal (HPA) axis activity. Yet, compared to Fischer 344 (F344) rats, Lewis rats have hyporesponsive HPA axis function and more readily acquire cocaine self-administration. We hypothesized that stress would differentially affect cocaine behaviors in these strains. The effects of three stressors on the discriminative stimulus and response rate effects of cocaine were investigated. Rats of both strains were trained to discriminate cocaine (10 mg/kg) from saline using a two-lever, food-reinforced (FR10) procedure. Immediately prior to cumulative dose (1, 3, 10 mg/kg cocaine) test sessions, rats were restrained for 15-min, had 15-min …

Love-Variant: The Wakin-Vo I. D. R. Model Of Limerence, Albert H. Wakin, Duyen B. Vo

Psychology Faculty Publications

The purpose of the current paper is to 1) propose the Wakin-Vo I.D.R model of limerence and 2) establish grounds for the scientific query of limerence. Limerence is an involuntary interpersonal state that involves intrusive, obsessive, and compulsive thoughts, feelings, and behaviors that are contingent on perceived emotional reciprocation from the object of interest. The model that the authors propose holds that although limerence resembles normative love, it is a state that is necessarily negative, problematic, and impairing, with clinical implications. The model frames limerence as consisting of three functional components: initiating force, driving forces, and resultant forces. Parallels between …

Alcohol Addiction And Social Work Practice: A Holistic Paradigm, Nelson Henning, Michael W. Firmin

Psychology Faculty Publications

The Christian who practices social work can be uniquely qualified to provide services to individuals who are struggling with alcohol addiction. This paper supports the concept that there is a holistic paradigm social workers can use in acquiring a broad understanding of alcohol addiction. An overview of contemporary theories associated with alcohol abuse is presented along with a biblical means of understanding alcohol addiction. Implications for social work practice within a Christian context are discussed.