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Social and Behavioral Sciences Commons™
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Articles 1 - 3 of 3
Full-Text Articles in Social and Behavioral Sciences
Chronic Hippocampal Abnormalities And Blunted Hpa Axis In An Animal Model Of Repeated Unpredictable Stress, Moustafa Algamal, Joseph O. Ojo, Carlyn P. Lungmus, Phillip Muza, Constance Cammarata, Margaret J. Owens, Benoit C. Mouzon, David M. Diamond, Michael Mullan, Fiona Crawford
Chronic Hippocampal Abnormalities And Blunted Hpa Axis In An Animal Model Of Repeated Unpredictable Stress, Moustafa Algamal, Joseph O. Ojo, Carlyn P. Lungmus, Phillip Muza, Constance Cammarata, Margaret J. Owens, Benoit C. Mouzon, David M. Diamond, Michael Mullan, Fiona Crawford
Psychology Faculty Publications
Incidence of post-traumatic stress disorder (PTSD) ranges from 3 to 30% in individuals exposed to traumatic events, with the highest prevalence in groups exposed to combat, torture, or rape. To date, only a few FDA approved drugs are available to treat PTSD, which only offer symptomatic relief and variable efficacy. There is, therefore, an urgent need to explore new concepts regarding the biological responses causing PTSD. Animal models are an appropriate platform for conducting such studies. Herein, we examined the chronic behavioral and neurobiological effects of repeated unpredictable stress (RUS) in a mouse model. 12 weeks-old C57BL/6J male mice were …
The Role Of Stress In The Pathogenesis And Maintenance Of Obsessive-Compulsive Disorder, Thomas G. Adams, Benjamin Kelmendi, C. Alex Brake, Patricia Gruner, Christal L. Badour, Christopher Pittenger
The Role Of Stress In The Pathogenesis And Maintenance Of Obsessive-Compulsive Disorder, Thomas G. Adams, Benjamin Kelmendi, C. Alex Brake, Patricia Gruner, Christal L. Badour, Christopher Pittenger
Psychology Faculty Publications
Individuals with obsessive-compulsive disorder often identify psychosocial stress as a factor that exacerbates their symptoms, and many trace the onset of symptoms to a stressful period of life or a discrete traumatic incident. However, the pathophysiological relationship between stress and obsessive-compulsive disorder remains poorly characterized: it is unclear whether trauma or stress is an independent cause of obsessive-compulsive disorder symptoms, a triggering factor that interacts with a preexisting diathesis, or simply a nonspecific factor that can exacerbate obsessive-compulsive disorder along with other aspects of psychiatric symptomatology. Nonetheless, preclinical research has demonstrated that stress has conspicuous effects on corticostriatal and limbic …
Measuring Sexual Minority Stressors In Lesbians Women's Daily Lives: Initial Scale Development, Kristin Heron, Abby L. Braitman, Robin J. Lewis, Alexander T. Shappie, Phoebe T. Hitson
Measuring Sexual Minority Stressors In Lesbians Women's Daily Lives: Initial Scale Development, Kristin Heron, Abby L. Braitman, Robin J. Lewis, Alexander T. Shappie, Phoebe T. Hitson
Psychology Faculty Publications
Lesbian women face unique sexual minority stressors (SMS) because of their stigmatized and marginalized status in society. Existing studies of SMS are primarily cross-sectional and use global measures of SMS. The goal of the present study was to develop a brief daily measure of SMS for use in daily diary or ecological momentary assessment studies. Existing retrospective measures of SMS were reviewed, resulting in an initial pool of 29 items. Thirty-eight lesbian women (Mage = 24.3 years, range: 19–30 years) completed a daily web-based survey including the SMS items for 12 days. Two response scales were tested; participants were randomized …