Social and Behavioral Sciences Commons^™

Are Enzymes Accurate Indicators Of Postmortem Interval?: A Biochemical Analysis, Karly Laine Buras

LSU Master's Theses

There are numerous ways to estimate postmortem interval (PMI), or time since death, including body temperature, rigor mortis, insect activity, and decomposition. Individually, many of these indicators are prone to inaccuracy due to the influence of the external environment upon them. This study proposed that in addition to or in conjunction with these and other indicators, certain enzymes could be used to accurately determine PMI, namely aspartate aminotransferase (AST), alcohol dehydrogenase (ADH), creatine kinase (CK), and lactate dehydrogenase (LDH). In this project, 18 rats were studied postmortem to determine how ethanol consumption and different environments affect decomposition and enzyme activity. …