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Faculty of Engineering and Information Sciences - Papers: Part A

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Towards Soft Robotic Devices For Site-Specific Drug Delivery, Gursel Alici Jan 2015

Towards Soft Robotic Devices For Site-Specific Drug Delivery, Gursel Alici

Faculty of Engineering and Information Sciences - Papers: Part A

Considerable research efforts have recently been dedicated to the establishment of various drug delivery systems (DDS) that are mechanical/physical, chemical and biological/molecular DDS. In this paper, we report on the recent advances in site-specific drug delivery (site-specific, controlled, targeted or smart drug delivery are terms used interchangeably in the literature, to mean to transport a drug or a therapeutic agent to a desired location within the body and release it as desired with negligibly small toxicity and side effect compared to classical drug administration means such as peroral, parenteral, transmucosal, topical and inhalation) based on mechanical/physical systems consisting of implantable …


Specific Yield For A Two-Dimensional Flow, Peter Tritscher, W Wayne Read, Philip Broadbridge Jan 2000

Specific Yield For A Two-Dimensional Flow, Peter Tritscher, W Wayne Read, Philip Broadbridge

Faculty of Engineering and Information Sciences - Papers: Part A

We investigate the systematic secular spatial variation of specific yield. As a vehicle for this analysis we consider a canonical unconfined aquifer consisting of a porous zone whose cross section is a simple long rectangle. The hydraulic conductivity in the unsaturated zone is modeled by the quasi-linear approximation. We find that locally the specific yield may be strongly influenced by the water table depth and mildly dependent on the recharge rate if that rate is high. For the simple geometry considered, a lateral component of flow has been found to have an insignificant effect on the local specific yield and …


Identification Of Giardia Lamblia-Specific Antigens In Infected Human And Gerbil Feces By Western Immunoblotting, Henry H. Stibbs, Mansour Samadpour, Jerry E. Ongerth Jan 1990

Identification Of Giardia Lamblia-Specific Antigens In Infected Human And Gerbil Feces By Western Immunoblotting, Henry H. Stibbs, Mansour Samadpour, Jerry E. Ongerth

Faculty of Engineering and Information Sciences - Papers: Part A

Western immunoblot analysis of aqueous extracts of feces obtained from five giardiasis patients and from experimentally infected gerbils (Meriones unguiculatus) with rabbit antiserum to Giardia lamblia cysts has revealed antigens of three molecular weight groups. A stepladderlike, evenly-spaced set of strongly reactive antigens (darkest at a molecular weight [m.w.] of 55,000 to 70,000) appeared in the gerbil feces from day 4 (first experiment) or day 2 (second experiment) and lasted to about day 7 but disappeared completely by day 8 and did not reappear later. These antigenic bands were seen in gerbils infected with two isolates of G. lamblia. These …