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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
Stress And Substance Abuse In Homeless And Matched Housed Adolescents: A Longitudinal Model, Corissa Carlson
Stress And Substance Abuse In Homeless And Matched Housed Adolescents: A Longitudinal Model, Corissa Carlson
Wayne State University Theses
The relationship between stress and substance abuse within an at-risk adolescent population is an important topic to research. There are several models examining the relationship between stress and substance abuse; however, this study will look to longitudinal methods to examine if there is a temporal relationship between stress and substance abuse in a high risk population. Interviews were conducted at a baseline time point as well as follow-up time points at two, five, and seven years. Two hundred fifty-four participants were retained at the two year follow-up and their data were analyzed using structural equation modeling. The two proposed models …
Protective Effects Of The Alcohol Dehydrogenase-Adh1b Allele, Neil Dodge
Protective Effects Of The Alcohol Dehydrogenase-Adh1b Allele, Neil Dodge
Wayne State University Theses
Alcohol dehydrogenase is a critical enzyme in the metabolism of alcohol. Expression of three alleles at the ADH1B locus results in enzymes that differ in turnover rate and affinity for alcohol. The ADH1B*3 allele, which appears to be unique to African Americans, is associated with more rapid alcohol metabolism than the more prevalent ADH1B*1 allele. It has been previously demonstrated that the presence of at least one maternal ADH1B*3 allele confers a protective effect against alcohol teratogenicity in African American infants and children. This study was conducted to determine whether the presence of the ADH1B*3 allele in the mother or …