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Full-Text Articles in Social and Behavioral Sciences
Evidence For Sample Selection Effect And Hawthorne Effect In Behavioural Hiv Prevention Trial Among Young Women In A Rural South African Community, Molly Rosenberg, Audrey Pettifor, Rhian Twine, James Hughes, F Gomez-Olive, Ryan Wagner, Afolabi Sulaimon, Stephen Tollman, Amanda Selin, Catherine L. Mac Phail, Kathleen Kahn
Evidence For Sample Selection Effect And Hawthorne Effect In Behavioural Hiv Prevention Trial Among Young Women In A Rural South African Community, Molly Rosenberg, Audrey Pettifor, Rhian Twine, James Hughes, F Gomez-Olive, Ryan Wagner, Afolabi Sulaimon, Stephen Tollman, Amanda Selin, Catherine L. Mac Phail, Kathleen Kahn
Faculty of Social Sciences - Papers (Archive)
Objectives We examined the potential influence of both sample selection effects and Hawthorne effects in the behavioural HIV Prevention Trial Network 068 study, designed to examine whether cash transfers conditional on school attendance reduce HIV acquisition in young South African women. We explored whether school enrolment among study participants differed from the underlying population, and whether differences existed at baseline (sample selection effect) or arose during study participation (Hawthorne effect). Methods We constructed a cohort of 3889 young women aged 11-20 years using data from the Agincourt Health and socio-Demographic Surveillance System. We compared school enrolment in 2011 (trial start) …
Effect Of Cannabis Use In People With Chronic Non-Cancer Pain Prescribed Opioids: Findings From A 4-Year Prospective Cohort Study, Gabrielle Campbell, Wayne Hall, Amy Peacock, Nicholas Lintzeris, Raimondo Bruno, Briony K. Larance, Suzanne Nielsen, Milton Cohen, Gary Chan, Richard P. Mattick, Fiona Blyth, Marian D. Shanahan, Timothy Dobbins, Michael P. Farrell, Louisa Degenhardt
Effect Of Cannabis Use In People With Chronic Non-Cancer Pain Prescribed Opioids: Findings From A 4-Year Prospective Cohort Study, Gabrielle Campbell, Wayne Hall, Amy Peacock, Nicholas Lintzeris, Raimondo Bruno, Briony K. Larance, Suzanne Nielsen, Milton Cohen, Gary Chan, Richard P. Mattick, Fiona Blyth, Marian D. Shanahan, Timothy Dobbins, Michael P. Farrell, Louisa Degenhardt
Faculty of Social Sciences - Papers (Archive)
Background Interest in the use of cannabis and cannabinoids to treat chronic non-cancer pain is increasing, because of their potential to reduce opioid dose requirements. We aimed to investigate cannabis use in people living with chronic non-cancer pain who had been prescribed opioids, including their reasons for use and perceived effectiveness of cannabis; associations between amount of cannabis use and pain, mental health, and opioid use; the effect of cannabis use on pain severity and interference over time; and potential opioid-sparing effects of cannabis. Methods The Pain and Opioids IN Treatment study is a prospective, national, observational cohort of people …
Radiosensitisation Enhancement Effect Of Brudr And Ta2o5 Nsps In Combination With 5-Fluorouracil Antimetabolite In Kilovoltage And Megavoltage Radiation, Marjorie Mcdonald, Sianne Oktaria, Konstantin K. Konstantinov, Anatoly B. Rosenfeld, Michael L. F Lerch, Stephanie Corde, Moeava Tehei
Radiosensitisation Enhancement Effect Of Brudr And Ta2o5 Nsps In Combination With 5-Fluorouracil Antimetabolite In Kilovoltage And Megavoltage Radiation, Marjorie Mcdonald, Sianne Oktaria, Konstantin K. Konstantinov, Anatoly B. Rosenfeld, Michael L. F Lerch, Stephanie Corde, Moeava Tehei
Faculty of Engineering and Information Sciences - Papers: Part B
This article demonstrates in vitro a synergistic effect on 9L gliosarcoma cells when exposed to bromodeoxyuridine (BrUdR) and a low concentration (100 times lower than the IC50) of 5-Fluorouracil (5-FU), in combination with x-ray irradiation. The synergy is brought about by several important factors including the x-ray beam energy, atomic number of the BrUdR (Z = 35), effectiveness of 5-FU in reducing the available repair processes and distribution of the BrUdR in and around the 9L cells (32% of the total substitution of BrUdR for thymidine into nucleus DNA). Our results show that the synergistic effect, evident in an optimised …