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Full-Text Articles in Social and Behavioral Sciences
Improved Initial Class Diagrams With Atsa:Oo, Robert B. K Brown, Angela Piper
Improved Initial Class Diagrams With Atsa:Oo, Robert B. K Brown, Angela Piper
Faculty of Engineering and Information Sciences - Papers: Part A
Despite the popularity of Object Oriented programming and design, their analysis phase is difficult to learn and relies heavily on the analyst's intuition and experience. Even industry practitioners can produce initial class diagrams requiring time-consuming refinements in the design phase. Business clients can find it difficult to follow its diverse techniques and constructs. The A TSA method offers analysis under a single theoretical framework that is specifically designed to be easily understood by both neophyte practitioners and business clients. However as it follows the procedural paradigm, it is not suitable for direct 00 application. This paper presents an adaptation of …
Structural Insights Into The Dehydroascorbate Reductase Activity Of Human Omega-Class Glutathione Transferases, Huina Zhou, Joseph Brock, Dan Liu, Philip G. Board, Aaron J. Oakley
Structural Insights Into The Dehydroascorbate Reductase Activity Of Human Omega-Class Glutathione Transferases, Huina Zhou, Joseph Brock, Dan Liu, Philip G. Board, Aaron J. Oakley
Faculty of Science - Papers (Archive)
The reduction of dehydroascorbate (DHA) to ascorbic acid (AA) is a vital cellular function. The omega-class glutathione transferases (GSTs) catalyze several reductive reactions in cellular biochemistry, including DHA reduction. In humans, two isozymes (GSTO1-1 and GSTO2-2) with significant DHA reductase (DHAR) activity are found, sharing 64% sequence identity. While the activity of GSTO2-2 is higher, it is significantly more unstable in vitro. We report the first crystal structures of human GSTO2-2, stabilized through site-directed mutagenesis and determined at 1.9Å resolution in the presence and absence of glutathione (GSH). The structure of a human GSTO1-1 has been determined at 1.7Å resolution …
An Empirical Case For Introductory Psychology Tutorials In A Large-Class Format, Amy Y. C Chan, Chris Brewer, Jessica L. Browne
An Empirical Case For Introductory Psychology Tutorials In A Large-Class Format, Amy Y. C Chan, Chris Brewer, Jessica L. Browne
Faculty of Health and Behavioural Sciences - Papers (Archive)
This study examined the effectiveness of an instructional format that Involved conducting introductory psychology tutorials in large conventional kdure theatres with over 100 students per cia s. We maximised the u e of ~killed tutors, ' hari n ~ of studem perspectives, and cooperative k arning in delivering interactive, aClive learn ing activities, Studenls (N = 284) wilh in l'm:h class were randomly assigned to smaller groups th'\I were scaled within the same large class environment (Ud'l1l:' rep >ned posi ti e t 'rception of Ihei r learning experience at an end-of-semester survey. Moreover, lhey performed significantly better in a …