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Articles 1 - 11 of 11
Full-Text Articles in Social and Behavioral Sciences
Land Management Practices Associated With House Loss In Wildfires, Philip Gibbons, Linda Van Bommel, A Malcolm Gill, Geoffrey J. Cary, Don A. Driscoll, Ross A. Bradstock, Emma Knight, Max A. Moritz, Scott L. Stephens, David B. Lindenmayer
Land Management Practices Associated With House Loss In Wildfires, Philip Gibbons, Linda Van Bommel, A Malcolm Gill, Geoffrey J. Cary, Don A. Driscoll, Ross A. Bradstock, Emma Knight, Max A. Moritz, Scott L. Stephens, David B. Lindenmayer
Faculty of Science - Papers (Archive)
Losses to life and property from unplanned fires (wildfires) are forecast to increase because of population growth in periurban areas and climate change. In response, there have been moves to increase fuel reduction—clearing, prescribed burning, biomass removal and grazing—to afford greater protection to peri-urban communities in fire-prone regions. But how effective are these measures? Severe wildfires in southern Australia in 2009 presented a rare opportunity to address this question empirically. We predicted that modifying several fuels could theoretically reduce house loss by 76%–97%, which would translate to considerably fewer wildfire-related deaths. However, maximum levels of fuel reduction are unlikely to …
Activation Of The Damage-Associated Molecular Pattern Receptor P2x7 Induces Interleukin-1b Release From Canine Monocytes, Iman Jalilian, Michelle Peranec, Belinda L. Curtis, Aine Seavers, Mari Spildrejorde, Vanessa Sluyter, Ronald Sluyter
Activation Of The Damage-Associated Molecular Pattern Receptor P2x7 Induces Interleukin-1b Release From Canine Monocytes, Iman Jalilian, Michelle Peranec, Belinda L. Curtis, Aine Seavers, Mari Spildrejorde, Vanessa Sluyter, Ronald Sluyter
Faculty of Science - Papers (Archive)
P2X7, a damage-associated molecular pattern receptor and adenosine 5'-triphosphate (ATP)-gated cation channel, plays an important role in the activation of the NALP3 inflammasome and subsequent release of interleukin (IL)-1β from human monocytes; however its role in monocytes from other species including the dog remains poorly defined. This study investigated the role of P2X7 in canine monocytes, including its role in IL-1β release. A fixed-time flow cytometric assay demonstrated that activation of P2X7 by extracellular ATP induces the uptake of the organic cation, YO-PRO-12+, into peripheral blood monocytes from various dog breeds, a process impaired by the specific P2X7 …
Corrigendum To ‘‘The Chaperone Action Of Bovine Milk As1- And As2-Caseins And Their Associated Form As-Casein’’ [Arch. Biochem. Biophys. 510 (2011) 42–52], Teresa M. Treweek, David C. Thorn, William E. Price, John A. Carver
Corrigendum To ‘‘The Chaperone Action Of Bovine Milk As1- And As2-Caseins And Their Associated Form As-Casein’’ [Arch. Biochem. Biophys. 510 (2011) 42–52], Teresa M. Treweek, David C. Thorn, William E. Price, John A. Carver
Faculty of Science - Papers (Archive)
No abstract provided.
Soil Geochemistry And Pathfinder Element Distribution Associated With The Hillgrove Antimony-Gold-Tungsten Deposit, New England Orogen, Nsw, R Ellsmore, Solomon Buckman, C Simpson
Soil Geochemistry And Pathfinder Element Distribution Associated With The Hillgrove Antimony-Gold-Tungsten Deposit, New England Orogen, Nsw, R Ellsmore, Solomon Buckman, C Simpson
Faculty of Science - Papers (Archive)
No abstract provided.
Silica-Carbonate (Listwanites) Related Gold Mineralisation Associated With Epithermal Alteration Of Serpentinite Bodies, Solomon Buckman, P Ashley
Silica-Carbonate (Listwanites) Related Gold Mineralisation Associated With Epithermal Alteration Of Serpentinite Bodies, Solomon Buckman, P Ashley
Faculty of Science - Papers (Archive)
No abstract provided.
Alphab-Crystallin Inhibits The Cell Toxicity Associated With Amyloid Fibril Formation By Kappa-Casein And The Amyloid-Beta Peptide, Francis C. Dehle, Heath Ecroyd, Ian F. Musgrave, John A. Carver
Alphab-Crystallin Inhibits The Cell Toxicity Associated With Amyloid Fibril Formation By Kappa-Casein And The Amyloid-Beta Peptide, Francis C. Dehle, Heath Ecroyd, Ian F. Musgrave, John A. Carver
Faculty of Science - Papers (Archive)
Amyloid fibril formation is associated with diseases such as Alzheimer’s, Parkinson’s, and prion diseases. Inhibition of amyloid fibril formation by molecular chaperone proteins, such as the small heat-shock protein αB-crystallin, may play a protective role in preventing the toxicity associated with this form of protein misfolding. Reduced and carboxymethylated κ-casein (RCMκ-CN), a protein derived from milk, readily and reproducibly forms fibrils at physiological temperature and pH. We investigated the toxicity of fibril formation by RCMκ-CN using neuronal model PC12 cells and determined whether the inhibition of fibril formation altered its cell toxicity. To resolve ambiguities in the literature, we also …
Myriocin-Mediated Up-Regulation Of Hepatocyte Apoa-I Synthesis Is Associated With Erk Inhibition, Elias N. Glaros, Woojin Scott Kim, Brett Garner
Myriocin-Mediated Up-Regulation Of Hepatocyte Apoa-I Synthesis Is Associated With Erk Inhibition, Elias N. Glaros, Woojin Scott Kim, Brett Garner
Faculty of Science - Papers (Archive)
Sphingolipids including sphingomyelin have been implicated as potential atherogenic lipids. Studies in apoE (apolipoprotein E)-null mice have revealed that the serine palmitoyltransferase inhibitor myriocin reduces plasma levels of sphingomyelin, ceramide, sphingosine-I-phosphate and glycosphingolipids and that this is associated with potent inhibition of atherosclerosis. Interestingly, hepatic apoA-I (apolipoprotein A-I) synthesis and plasma HDL (high-density lipoprotein)cholesterol levels were also increased in apoE-null mice treated with myriocin. Since myriocin is a known inhibitor of ERK (extracellular-signal-related kinase) phosphorylation, we assessed the possibility that myriocin may be acting to increase hepatic apoA-I production via this pathway. To address this, HepG2 cells and primary mouse …
Structure, Detrital Zircon U-Pb Ages And 40ar/39ar Geochronology Of The Early Palaeozoic Girilambone Group, Central New South Wales: Subduction, Contraction And Extension Associated With The Benambran Orogeny, Christopher L. Fergusson, C M Fanning, D. Phillips, Benjamin Ackerman
Structure, Detrital Zircon U-Pb Ages And 40ar/39ar Geochronology Of The Early Palaeozoic Girilambone Group, Central New South Wales: Subduction, Contraction And Extension Associated With The Benambran Orogeny, Christopher L. Fergusson, C M Fanning, D. Phillips, Benjamin Ackerman
Faculty of Science - Papers (Archive)
The Early Palaeozoic Cape River Metamorphics consist mainly of psammitic gneiss and schist and occur as an extensive linear belt at the western margin of the Charters Towers Province 200 km southwest of Townsville in the northern Tasmanides. A prominent foliation (S2) is the main structure in the belt and is associated with tight to isoclinal folds, subparallel mineral and intersection lineations, and boudinaged pods of vein quartz and pegmatite. In the southwest, the main foliation is a crenulation cleavage (S2) related to D2 deformation. It overprints steeply dipping foliation (S1) formed in …
Analysis Of The Mechanism By Which Calcium Negatively Regulates The Tyrosine Phosphorylation Cascade Associated With Sperm Capacitation, Mark Baker, Louise Hethrington, Heath W. Ecroyd, Shaun D. Roman, Robert J. Aitken
Analysis Of The Mechanism By Which Calcium Negatively Regulates The Tyrosine Phosphorylation Cascade Associated With Sperm Capacitation, Mark Baker, Louise Hethrington, Heath W. Ecroyd, Shaun D. Roman, Robert J. Aitken
Faculty of Science - Papers (Archive)
The capacitation of mammalian spermatozoa involves the activation of a cAMP-mediated signal transduction pathway that drives tyrosine phosphorylation via mechanisms that are unique to this cell type. Controversy surrounds the impact of extracellular calcium on this process, with positive and negative effects being recorded in independent publications. We clearly demonstrate that the presence of calcium in the external medium decreases tyrosine phosphorylation in both human and mouse spermatozoa. Under these conditions, a rise in intracellular pH was recorded, however, this event was not responsible for the observed changes in phosphotyrosine expression. Rather, the impact of calcium on tyrosine phosphorylation in …
Endogenous Redox Activity In Mouse Spermatozoa And Its Role In Regulating The Tyrosine Phosphorylation Events Associated With Sperm Capacitation, Heath W. Ecroyd, Russell C. Jones, Robert J. Aitken
Endogenous Redox Activity In Mouse Spermatozoa And Its Role In Regulating The Tyrosine Phosphorylation Events Associated With Sperm Capacitation, Heath W. Ecroyd, Russell C. Jones, Robert J. Aitken
Faculty of Science - Papers (Archive)
We investigated the role of endogenous redox activity in regulating the signal transduction pathway leading to tyrosine phosphorylation in mouse spermatozoa. Endogenous redox activity was monitored using a luminol-peroxidase chemiluminescent probe. Chemiluminescence increased in spermatozoa that were actively undergoing cAMP-mediated tyrosine phosphorylation events associated with capacitation and was inhibited in a dose-dependent manner by addition of catalase or diphenylene iodonium, both of which also inhibited tyrosine phosphorylation within the cell at points downstream of cAMP. Excluding bicarbonate from the incubation medium reduced the redox activity of sperm by 80-90% and dramatically reduced tyrosine phosphorylation. This study provides the first evidence …
Enhanced Tumor Growth In Uv-Irradiated Skin Is Associated With An Influx Of Inflammatory Cells Into The Epidermis, Ronald Sluyter, Gary M. Halliday
Enhanced Tumor Growth In Uv-Irradiated Skin Is Associated With An Influx Of Inflammatory Cells Into The Epidermis, Ronald Sluyter, Gary M. Halliday
Faculty of Science - Papers (Archive)
UV radiation causes a number of cellular changes within the skin which play a role in tumor outgrowth, including immunosuppression and production of growth-enhancing cytokines, Both of these enable tumors to grow but their relative importance in carcinogenesis is poorly defined. In this study, C3H/HeN mice were exposed to a single inflammatory dose of 410 mJ/cm(2) UVB radiation (plus 100 mJ/cm2 UVA radiation) followed by the inoculation of a regressor squamous cell carcinoma into or the painting of oxazolone onto the treated skin. Tumors transplanted 2 or 3 but not 4 days after irradiation had a significantly higher growth rate …