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A Review Of Recruitment, Adherence And Drop-Out Rates In Omega-3 Polyunsaturated Fatty Acid Supplementation Trials In Children And Adolescents, Inge S. M Van Der Wurff, Barbara J. Meyer, Renate H. M De Groot

Faculty of Science, Medicine and Health - Papers: part A

Introduction: The influence of n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) supplementation on health outcomes has been studied extensively with randomized controlled trials (RCT). In many research fields, difficulties with recruitment, adherence and high drop-out rates have been reported. However, what is unknown is how common these problems are in n-3 LCPUFA supplementation studies in children and adolescents. Therefore, this paper will review n-3 LCPUFA supplementation studies in children and adolescents with regard to recruitment, adherence and drop-out rates. Methods: The Web of Science, PubMed and Ovid databases were searched for papers reporting on RCT supplementing children and adolescents (2¿18 …