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Social and Behavioral Sciences Commons

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University of South Carolina

Theses and Dissertations

Motivation

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Full-Text Articles in Social and Behavioral Sciences

Hiv-1 And Cocaine: Motivation And Synaptic Function, Sarah J. Bertrand May 2015

Hiv-1 And Cocaine: Motivation And Synaptic Function, Sarah J. Bertrand

Theses and Dissertations

Molecular and behavioral assays were used to examine the effects of HIV-1 on synaptodendritic integrity, motivated behavior and the therapeutic potential of natural isoflavones in ameliorating both synaptodendritic injury in vitro and changes in motivation in vivo. The overarching hypothesis of the present dissertation is twofold: 1. HIV-1 causes a decrease in motivation for sucrose and cocaine and the change in motivational state is driven by compromised synaptic integrity as evaluated by F-actin and DAT function and, 2. Treatment with phytoestrogens will prevent synaptodendritic damage, normalize the internal motivational state of the HIV-1 Tg rat for sucrose and cocaine, and …


Defining And Supporting Organizational Readiness In The Interactive Systems Framework For Dissemination And Implementaion, Jonathan Peter Scaccia Dec 2014

Defining And Supporting Organizational Readiness In The Interactive Systems Framework For Dissemination And Implementaion, Jonathan Peter Scaccia

Theses and Dissertations

Introduction. In the implementation literature, organizational readiness is associated with an increased likelihood of achieving innovation outcomes. Organizational readiness consists of organizational capacity (general and innovation-specific) and organization motivation. Organizations who wish to get results from their innovations have an interest in making sure that certain factors and subcomponents are in place. However, having awareness that certain capacities and factors that influence motivation are linked to improved innovation outcomes does not necessarily help organizations to get “more ready.” There is a need for organizations to know if and how they can effectively put these factors and subcomponents into place. This …


Delivery System Capacities For Recovery-Oriented System Of Care (Rosc) For Substance Abuse Disorders: An Examination Of Organizational Readiness, Jonathan Peter Scaccia Jan 2013

Delivery System Capacities For Recovery-Oriented System Of Care (Rosc) For Substance Abuse Disorders: An Examination Of Organizational Readiness, Jonathan Peter Scaccia

Theses and Dissertations

Adopting and implementing a Recovery-Oriented System of Care (ROSC) (innovation) requires that organizations have recovery-specific systems and features (capacities) in place. Organizations, however, may requires more than specific capacities, they require the motivation to put recovery-based innovations into place. This thesis reviews the literature to examine which capacities have been identified as integral to providing recovery-oriented services within a ROSC. Surveys were distributed electronically to delivery and support staff at organizations that provide substance abuse services under the jurisdiction of the South Carolina Department of Alcohol and Drug Abuse Services. Confirmatory Factor Analysis (CFA) was used to examine how these …