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Social and Behavioral Sciences Commons™
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Articles 1 - 2 of 2
Full-Text Articles in Social and Behavioral Sciences
Regulation Of Gabaa Receptor Subunit Expression In Substance Use Disorders, Jeffrey S. Barker, Rochelle M. Hines
Regulation Of Gabaa Receptor Subunit Expression In Substance Use Disorders, Jeffrey S. Barker, Rochelle M. Hines
Psychology Faculty Research
The modulation of neuronal cell firing is mediated by the release of the neurotransmitter GABA (γ-aminobuytric acid), which binds to two major families of receptors. The ionotropic GABAA receptors (GABAARs) are composed of five distinct subunits that vary in expression by brain region and cell type. The action of GABA on GABAARs is modulated by a variety of clinically and pharmacologically important drugs such as benzodiazepines and alcohol. Exposure to and abuse of these substances disrupts homeostasis and induces plasticity in GABAergic neurotransmission, often via the regulation of receptor expression. Here, we review the regulation of GABAAR subunit expression in …
The Internal, External And Extended Microbiomes Of Hominins, Robert R. Dunn, Katherine R. Amato, Elizabeth A. Archie, Mimi Arandjelovic, Alyssa N. Crittenden, Lauren M. Nichols
The Internal, External And Extended Microbiomes Of Hominins, Robert R. Dunn, Katherine R. Amato, Elizabeth A. Archie, Mimi Arandjelovic, Alyssa N. Crittenden, Lauren M. Nichols
Anthropology Faculty Research
The social structure of primates has recently been shown to influence the composition of their microbiomes. What is less clear is how primate microbiomes might in turn influence their social behavior, either in general or with particular reference to hominins. Here we use a comparative approach to understand how microbiomes of hominins have, or might have, changed since the last common ancestor (LCA) of chimpanzees and humans, roughly six million years ago. We focus on microbiomes associated with social evolution, namely those hosted or influenced by stomachs, intestines, armpits, and food fermentation. In doing so, we highlight the potential influence …