Social and Behavioral Sciences Commons^™

Integrating Spatial Working Memory And Remote Memory: Interactions Between The Medial Prefrontal Cortex And Hippocampus, Ryan A. Wirt, James M. Hyman

Psychology Faculty Research

In recent years, two separate research streams have focused on information sharing between the medial prefrontal cortex (mPFC) and hippocampus (HC). Research into spatial working memory has shown that successful execution of many types of behaviors requires synchronous activity in the theta range between the mPFC and HC, whereas studies of memory consolidation have shown that shifts in area dependency may be temporally modulated. While the nature of information that is being communicated is still unclear, spatial working memory and remote memory recall is reliant on interactions between these two areas. This review will present recent evidence that shows that …