Social and Behavioral Sciences Commons^™

The Nmda Receptor Glun2c Subunit Controls Cortical Excitatoryinhibitory Balance, Neuronal Oscillations And Cognitive Function, Subhash C. Gupta, Aparna Ravikrishnan, Jinxu Liu, Zhihao Mao, Ratnamala Pavuluri, Brandon G. Hillman, Pauravi J. Gandhi, Dustin J. Stairs, Ming Li, Rajesh R. Ugale, Daniel T. Monaghan, Shashank M. Dravid

Department of Psychology: Faculty Publications

Despite strong evidence for NMDA receptor (NMDAR) hypofunction as an underlying factor for cognitive disorders, the precise roles of various NMDAR subtypes remains unknown. The GluN2Ccontaining NMDARs exhibit unique biophysical properties and expression pattern, and lower expression of GluN2C subunit has been reported in postmortem brains from schizophrenia patients. We found that loss of GluN2C subunit leads to a shift in cortical excitatory-inhibitory balance towards greater inhibition. Specifically, pyramidal neurons in the medial prefrontal cortex (mPFC) of GluN2C knockout mice have reduced mEPSC frequency and dendritic spine density and a contrasting higher frequency of mIPSCs. In addition a greater number …

Antipsychotic Drugs On Maternal Behavior In Rats, Ming Li

Department of Psychology: Faculty Publications

Rat maternal behavior is a complex social behavior. Many clinically used antipsychotic drugs, including the typical drug haloperidol and atypical drugs clozapine, risperidone, olanzapine, quetiapine, aripiprazole and amisulpride, all disrupt active maternal responses (e.g. pup retrieval, pup licking and nest building) to various extents. In this review, I present a summary of recent studies on the behavioral effects and neurobiological mechanisms of antipsychotic action on maternal behavior in rats. I argue that antipsychotic drugs at the clinical relevant doses disrupt active maternal responses primarily by suppressing maternal motivation. Atypical drug-induced sedation also contributes to their disruptive effects, especially that on …

Emotion Moderates The Association Between Htr2a (Rs6313) Genotype And Antisaccade Latency, Mark S. Mills, Olivia Wieda, Scott F. Stoltenberg, Michael Dodd

Department of Psychology: Faculty Publications

The serotonin system is heavily involved in cognitive and emotional control processes. Previous work has typically investigated this system’s role in control processes separately for cognitive and emotional domains, yet it has become clear the two are linked. The present study, therefore, examined whether variation in a serotonin receptor gene (HTR2A, rs6313) moderated effects of emotion on inhibitory control. An emotional antisaccade task was used in which participants looked toward (prosaccade) or away (antisaccade) from a target presented to the left or right of a happy, angry, or neutral face. Overall, antisaccade latencies were slower for rs6313 C allele homozygotes …

Behavioral Effects Of Phencyclidine On Nicotine Self- Administration And Reinstatement In The Presence Or Absence Of A Visual Stimulus In Rats, Natashia Swalve, Steven T. Pittenger, Rick A. Bevins, Ming Li

Department of Psychology: Faculty Publications

Rationale—Tobacco use is a serious health problem in the United States and this problem is potentiated in patients with schizophrenia. The reward system is implicated in schizophrenia and may contribute to the high comorbidity between nicotine use and schizophrenia but very little research has been done on the topic. The reward-enhancement effect of nicotine has been shown to be important in nicotine use, but there have been no studies on this effect in animal models of schizophrenia.

Objectives—This study was designed to determine the effects of phencyclidine, used to model negative symptoms of schizophrenia, on self-administration of nicotine with or …

Differing Perspectives On Older Adult Caregiving, Eve M. Brank, Lindsey E. Wylie

Department of Psychology: Faculty Publications

Informal older adult caregiving allows older adults to stay in their homes or live with loved ones, but decisions surrounding older adult care are fraught with complexities. Related research and case law suggest that an older adult’s need for and refusal of help are important considerations; the current study is the first to examine these factors experimentally. Two samples (potential caregivers and care recipients) provided responses regarding anticipated emotions, caregiver abilities, and allocation of daily caregiving decision making based on a vignette portraying an older adult who had a high or low level of autonomy and who accepted or refused …

Daily Bidirectional Relationships Between Sleep And Mental Health Symptoms In Youth With Emotional And Behavioral Problems, Tori R. Van Dyk, Ronald W. Thompson, Timothy D. Nelson

Department of Psychology: Faculty Publications

Objective The present study examined the daily, bidirectional relationships between sleep and mental health symptoms in youth presenting to mental health treatment. Methods Youth aged 6 to 11 (36% female, 44% European American) presenting to outpatient behavioral health treatment (N = 25) were recruited to participate in the study. Children and parents completed daily questionnaires regarding the child’s sleep, mood, and behavior for a 14-day period, while youth wore an actigraph watch to objectively measure sleep. Results Examining between- and within-person variance using multilevel models, results indicate that youth had poor sleep duration and quality and that sleep and mental …

Distinct Stages Of Moment-To-Moment Processing In The Cinguloopercular And Frontoparietal Networks, C. Gratton, Maital Neta, H. Sun, E. J. Ploran, B. L. Schlaggar, M. E. Wheeler, S. E. Petersen, S. M. Nelson

Department of Psychology: Faculty Publications

Control of goal-directed tasks is putatively carried out via the cinguloopercular (CO) and frontoparietal (FP) systems. However, it remains unclear whether these systems showdissociable moment-to-moment processing during distinct stages of a trial. Here, we characterize dynamics in the CO and FP networks in a meta-analysis of 5 decision-making tasks using fMRI, with a specialized “slow reveal” paradigm which allows us to measure the temporal characteristics of trial responses.We find that activations in left FP, right FP, and CO systems form separate clusters, pointing to distinct roles in decision-making. Left FP shows early “accumulator-like” responses, suggesting a role in pre-decision processing. …

Modeling Postpartum Depression In Rats: Theoretic And Methodological Issues, Ming Li, Shinn-Yi Chou

Department of Psychology: Faculty Publications

The postpartum period is when a host of changes occur at molecular, cellular, physiological and behavioral levels to prepare female humans for the challenge of maternity. Alteration or prevention of these normal adaptions is thought to contribute to disruptions of emotion regulation, motivation and cognitive abilities that underlie postpartum mental disorders, such as postpartum depression. Despite the high incidence of this disorder, and the detrimental consequences for both mother and child, its etiology and related neurobiological mechanisms remain poorly understood, partially due to the lack of appropriate animal models. In recent decades, there have been a number of attempts to …

Distinctive Roles Of 5-Aza-2'-Deoxycytidine In Anterior Agranular Insular And Basolateral Amygdala In Reconsolidation Of Aversive Memory Associated With Morphine In Rats, Peng Liu, Jianjun Zhang, Ming Li, Nan Sui

Department of Psychology: Faculty Publications

5-aza-2'-deoxycytidine (5-aza), an inhibitor of DNA methyltransferases (DNMTs), has been implicated in aversive memory and the function of brain region involved in processing emotion. However, little is known about the role of 5-aza in the reconsolidation of opiate withdrawal memory. In the present study, using the morphinenaloxone induced conditioned place aversion (CPA) model in rats, we injected 5-aza into agranular insular (AI), granular insular (GI), basolateral amygdala (BLA) and central amygdala (CeA) immediately after the memory retrieval and tested the behavioral consequences at 24 h, 7 and 14 days after retrieval test. We found that 5-aza injection into AI disrupted …

Culturally Competent Evidence-Based Behavioral Health Services For The Transgender Community: Progress And Challenges, Debra A. Hope, Richard Mocarski, Chandra L. Bautista, Natalie R. Holt

Department of Psychology: Faculty Publications

The presence of individuals who identify as transgender has emerged into public awareness in the United States in recent years. Celebrities who publicly transition have expanded the national conversation about gender variation beyond gender and women’s studies classrooms and certain specialty health and mental health services. This increased public visibility has been accompanied by increased visibility in the mental health literature, including the publishing of competencies or guidelines for working with clients who identify as transgender by various professional organizations. However, rapid societal changes and increased understanding of the experience of being transgender in our society means literature can rapidly …

Exploring Lawyer Misconduct: An Examination Of The Self-Regulation Process, Nicole Leeper Piquero, Michele Bisaccia Meitl, Eve M. Brank, Jennifer L. Woolard, Lonn Lanza-Kaduce, Alex R. Piquero

Department of Psychology: Faculty Publications

Although white-collar professionals are often held in high esteem, sometimes persons in privileged positions engage in misconduct. Unfortunately, very little is known about the correlates associated with professional misconduct and even less is known about the sanctioning process among lawyers who are licensed by state bar associations and therefore subject to the bar rules regulating their professional conduct. We examine 213 complaints filed in one fiscal year with the Florida Bar alleging attorney misconduct and evaluate the factors that influence whether the complaint continued through or was discarded at each stage of the self-regulated grievance process. Using selection models that …

Applying Ecological Systems Theory To Sexual Revictimization Of Youth: A Review With Implications For Research And Practice, Samantha L. Pittenger, Terrence Z. Huit, David J. Hansen

Department of Psychology: Faculty Publications

This article reviews the literature on sexual revictimization, integrating findings from studies with adult and youth samples and organizing research evidence within a social ecological framework. Multiple victimization experiences are common among children, adolescents, and adults with histories of child sexual abuse; they are associated with negative cumulative effects on the individual and, through these negative sequelae, perpetuate a cycle of victimization. While much of the research has focused on individual factors that promote revictimization, there is emerging evidence that external influences on the individual may influence risk for subsequent victimization. Specifically, family, perpetrators, and engagement with helping professionals may …

Measuring Older Adult Confidence In The Courts And Law Enforcement, Joseph A. Hamm, Lindsey E. Wylie, Eve M. Brank

Department of Psychology: Faculty Publications

Older adults are an increasingly relevant subpopulation for criminal justice policy but, as yet, are largely neglected in the relevant research. The current research addresses this by reporting on a psychometric evaluation of a measure of older adults’ Confidence in Legal Institutions (CLI). Confirmatory factor analysis (CFA) provided support for the unidimensionality and reliability of the measures. In addition, participants’ CLI was related to cynicism, trust in government, dispositional trust, age, and education, but not income or gender. The results provide support for the measures of confidence in the courts and law enforcement, so we present the scale as a …

Antipsychotic-Induced Sensitization And Tolerance: Behavioral Characteristics, Developmental Impacts, And Neurobiological Mechanisms, Ming Li

Department of Psychology: Faculty Publications

Antipsychotic sensitization and tolerance refer to the increased and decreased drug effects due to past drug use, respectively. Both effects reflect the long-term impacts of antipsychotic treatment on the brain and result from the brain’s adaptive response to the foreign property of the drug. In this review, clinical evidence of the behavioral aspect of antipsychotic sensitization and tolerance is selectively reviewed, followed by an overview of preclinical literature that examines these behavioral characteristics and the related pharmacological and nonpharmacological factors. Next, recent work on the developmental impacts of adolescent antipsychotic sensitization and tolerance is presented and recent research that delineates …

Beliefs And Expectancies In Legal Decision Making: An Introduction To The Special Issue, Bradley D. Mcauliff, Brian H. Bornstein

Department of Psychology: Faculty Publications

This introduction describes what the co-editors believe readers can expect in this Special Issue. After beliefs and expectancies are defined, examples of how these constructs influence human thought, feeling, and behavior in legal settings are considered. Brief synopses are provided for the Special Issue papers on beliefs and expectancies regarding alibis, children’s testimony behavior, eyewitness testimony, confessions, sexual assault victims, judges’ decisions in child protection cases, and attorneys’ beliefs about jurors’ perceptions of juvenile offender culpability. Areas for future research are identified, and readers are encouraged to discover new ways that beliefs and expectancies operate in the legal system.

Modeling Postpartum Depression In Rats: Theoretic And Methodological Issues, Ming Li, Shinn-Yi Chou

Department of Psychology: Faculty Publications

The postpartum period is when a host of changes occur at molecular, cellular, physiological and behavioral levels to prepare female humans for the challenge of maternity. Alteration or prevention of these normal adaptions is thought to contribute to disruptions of emotion regulation, motivation and cognitive abilities that underlie postpartum mental disorders, such as postpartum depression. Despite the high incidence of this disorder, and the detrimental consequences for both mother and child, its etiology and related neurobiological mechanisms remain poorly understood, partially due to the lack of appropriate animal models. In recent decades, there have been a number of attempts to …

Socioeconomic Gaps In Early Childhood Experiences: 1998 To 2010, Daphna Bassok, Jenna E. Finch, Raehyuck Lee, Sean F. Reardon, Jane Waldfogel

Department of Psychology: Faculty Publications

This study compares the early life experiences of kindergarteners in 1998 and 2010 using two nationally representative data sets. We find that (a) young children in the later period are exposed to more books and reading in the home, (b) they have more access to educational games on computers, and (c) they engage with their parents more, inside and outside the home. Although these increases occurred among low- and high-income children, in many cases the biggest changes were seen among the lowest-income children. Our results indicate narrowing but still large early childhood parental investment gaps. In addition, socioeconomic gaps in …

The Cyber Aggression In Relationships Scale: A New Multidimensional Measure Of Technology-Based Intimate Partner Aggression, Laura E. Watkins, Rosalita C. Maldonado, David Dilillo

Department of Psychology: Faculty Publications

The purpose of this study was to develop and provide initial validation for a measure of adult cyber intimate partner aggression (IPA): the Cyber Aggression in Relationships Scale (CARS). Drawing on recent conceptual models of cyber IPA, items from previous research exploring general cyber aggression and cyber IPA were modified and new items were generated for inclusion in the CARS. Two samples of adults 18 years or older were recruited online. We used item factor analysis to test the factor structure, model fit, and invariance of the measure structure across women and men. Results confirmed that three-factor models for both …

Psychological Distress And Revictimization Risk In Youth Victims Of Sexual Abuse, Samantha L. Pittenger, Alayna Schreier, Katie Meidlinger, Jessica K. Pogue, Kate Theimer, Mary Fran Flood, David J. Hansen

Department of Psychology: Faculty Publications

Psychological distress, including depression and anxiety, has been associated with increased risk for sexual revictimization in youth who have experienced child sexual abuse. The present study utilized assessment information from treatment seeking youth with histories of sexual abuse to explore specific risk indicators for revictimization—risk taking, social problems, maladaptive cognitions, and posttraumatic stress—that may be indicated by self-reported distress. The relationship between initial levels of distress and change in symptoms over a 12-week course of treatment was also explored. Participants were 101 youth referred to a child-focused therapeutic group for victims of sexual abuse, 65 youth referred to an adolescent-focused …

Threat Assessment And Management In Higher Education In The United States: A Review Of The 10 Years Since The Mass Casualty Incident At Virginia Tech, Eugene R.D. Deisinger, Mario Scalora

Department of Psychology: Faculty Publications

Copyright © 2016 American Psychological Association. Used by permission.

Using Data Mining To Predict The Occurrence Of Respondent Retrieval Strategies In Calendar Interviewing: The Quality Of Retrospective Reports, Robert Belli, L. Dee Miller, Tarek Al Baghal, Leen-Kiat Soh

Department of Psychology: Faculty Publications

Determining which verbal behaviors of interviewers and respondents are dependent on one another is a complex problem that can be facilitated via data-mining approaches. Data are derived from the interviews of 153 respondents of the Panel Study of Income Dynamics (PSID) who were interviewed about their life-course histories. Behavioral sequences of interviewer-respondent interactions that were most predictive of respondents spontaneously using parallel, timing, duration, and sequential retrieval strategies in their generation of answers were examined. We also examined which behavioral sequences were predictive of retrospective reporting data quality as shown by correspondence between calendar responses with responses collected in prior …

Examining The Reasons For Student Responses To Threatening Behaviors On A College Campus, Heath J. Hodges, Elizabeth C. Low, M. Rosa Viñas-Racionero, Brandon A. Hollister, Mario Scalora

Department of Psychology: Faculty Publications

Underreporting criminal activity to authorities can pose significant challenges, particularly within college campuses. Crime prevention teams have recognized the importance of reporting potentially concerning behaviors that may precede violent acts. However, reasons for reporting preincident behaviors have been understudied among college samples and failed to account for informal responses, such as talking to third parties or changing personal security features. The present study surveyed 1,075 students from a midwestern state university and evaluated their awareness of threatening or concerning behaviors on campus, response behaviors, and reasons for either acting on or failing to report preincident behaviors. Findings reflected reporting rates …

Attention Deficit Hyperactivity Disorder Symptomatology And Pediatric Obesity: Psychopathology Or Sleep Deprivation?, Alyssa Lundahl, Timothy D. Nelson

Department of Psychology: Faculty Publications

The relationship between attention deficit hyperactivity disorder (ADHD) and obesity in children has received considerable attention in recent years. However, the literature currently overlooks the potential causal and maintaining role that sleep problems may play in this relationship. Using a biopsychosocial framework, this article highlights how sleep problems impact the biological, psychological, and social aspects of both ADHD symptomatology and obesity. An in-depth examination of this model illustrates the imperative need for future research and clinical practice to recognize and explore the role sleep has in the link between obesity and ADHD symptomatology.

A Face Versus Non-Face Context Influences Amygdala Responses To Masked Fearful Eye Whites, M. Justin Kim, Kimberly M. Solomon, Maital Neta, Caroline Davis, Jonathan A. Oler, Emily C. Mazzulla, Paul J. Whalen

Department of Psychology: Faculty Publications

The structure of the mask stimulus is crucial in backward masking studies and we recently demonstrated such an effect when masking faces. Specifically, we showed that activity of the amygdala is increased to fearful facial expressions masked with neutral faces and decreased to fearful expressions masked with a pattern mask – but critically both masked conditions discriminated fearful expressions from happy expressions. Given this finding, we sought to test whether masked fearful eye whites would produce a similar profile of amygdala response in a face vs. non-face context. During functional magnetic resonance imaging scanning sessions, 30 participants viewed fearful or …

Laboratory Notes From Behavioral Pharmacologists And Trainees: Considerations For The Discipline, Rick A. Bevins, Scott T. Barrett, Brady M. Thompson, Steven T. Pittenger

Department of Psychology: Faculty Publications

In several laboratory meetings, we discussed the challenges that face trainees in behavioral pharmacology. Major concerns, such as a difficult funding climate and limited academic job prospects were discussed at first. However, we decided to concentrate on ways to meet these challenges; versus focusing on negatives and listing gripes. Within this more constructive framework, we identified the importance of broadening training to aligned areas to enhance the capacity of behavioral pharmacologists to collaborate in multidisciplinary teams. With increased breadth of training comes the concern for a balance that does not cheat trainees out of the depth of training also needed …

All In The First Glance: First Fixation Predicts Individual Differences In Valence Bias, Maital Neta, Tien T. Tong, Monica L. Rosen, Alex Enersen, M. Justin Kim, Michael D. Dodd

Department of Psychology: Faculty Publications

Surprised expressions are interpreted as negative by some people, and as positive by others. When compared to fearful expressions, which are consistently rated as negative, surprise and fear share similar morphological structure (e.g., widened eyes), but these similarities are primarily in the upper part of the face (eyes). We hypothesized, then, that individuals would be more likely to interpret surprise positively when fixating faster to the lower part of the face (mouth). Participants rated surprised and fearful faces as either positive or negative while eye movements were recorded. Positive ratings of surprise were associated with longer fixation on the mouth …

Which Way Is Which? Examining Symbolic Control Of Attention With Compound Arrow Cues, Mark S. Mills, Michael Dodd

Department of Psychology: Faculty Publications

Spatial symbols can generate attentional biases toward peripheral locations compatible with the symbol’s meaning. An important question concerns how one symbol is selected when competing symbols are present. Studies examining this issue for spatially distinct symbols have suggested that selection depends on the task goals. In the present study, we examined whether the influence of competing symbolic stimuli (arrows) at different levels of structure on attentional control also depends on the task goals. Participants made simple detection responses to a peripheral target preceded by a spatially uninformative compound arrow (global arrow composed of local arrows). In addition, participants were required …

The Association Of Exposure To Point-Of-Sale Tobacco Marketing With Quit Attempt And Quit Success: Results From A Prospective Study Of Smokers In The United States, Mohammad Siahpush, Raees A. Shaikh, Danielle Smith, Andrew Hyland, K. Michael Cummings, Asia Sikora Kessler, Michael D. Dodd, Les Carlson, Jane L. Meza, Melanie Wakefield

Department of Psychology: Faculty Publications

The aim was to assess the association of exposure to point-of-sale (POS) tobacco marketing with quit attempt and quit success in a prospective study of smokers in the United States. Data were collected via telephone-interview on exposure to POS tobacco marketing, sociodemographic and smoking-related variables from 999 smokers in Omaha, Nebraska, in the United States. Exposure to POS tobacco marketing was measured by asking respondents three questions about noticing pack displays, advertisements, and promotions in their respective neighborhoods stores. These three variables were combined into a scale of exposure to POS tobacco marketing. About 68% of the respondents participated in …

Test–Retest, Retest, And Retest: Growth Curve Models Of Repeat Testing With Immediate Post-Concussion Assessment And Cognitive Testing (Impact), Arthur C. Maerlender, Caitlin J. Masterson, Tiffany D. James, Jonathan Beckwith, Per Gunner Brolinson, Joe Crisco, Stefan Duma, Laura A. Flashman, Rick Greenwald, Steven Rowson, Beth Wilcox, Tom W. Mcallister

Department of Psychology: Faculty Publications

Computerized neuropsychological testing has become an important tool in the identification and management of sports-related concussions; however, the psychometric effect of repeat testing has not been studied extensively beyond test–retest statistics. The current study analyzed data from Division I collegiate athletes who completed Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) baseline assessments at four sequential time points that varied over the course of their athletic careers. Administrations were part of a larger National Institutes of Health (NIH) study. Growth curve modeling showed that the two memory composite scores increased significantly with successive administrations: Change in Verbal Memory was best represented …

The Association Of Point-Of-Sale Cigarette Marketing With Cravings To Smoke: Results From A Cross-Sectional Population-Based Study, Mohammad Siahpush, Raees A. Shaikh, K. Michael Cummings, Andrew Hyland, Michael D. Dodd, Les Carlson, Asia Sikora Kessler, Jane L. Meza, Neng Wan, Melanie Wakefield

Department of Psychology: Faculty Publications

Objective—To examine the association between recalled exposure to point-of-sale (POS) cigarette marketing (ie, pack displays, advertisements and promotions such as discounts) and reported cravings to smoke while visiting a store. Methods—Data were collected using a telephone survey of a cross-sectional sample of 999 adult smokers in Omaha, Nebraska. Recalled exposure to POS cigarette marketing was measured by asking respondents about noticing (a) pack displays, (b) advertisements and (c) promotions in store in their neighbourhood. A 3-item scale indicating the frequency of experiencing cravings to smoke in locations where cigarettes are sold was created by asking respondents: (1) “feel …