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Full-Text Articles in Social and Behavioral Sciences

An Experimental And Computational Evaluation Of The Importance Of Molecular Diffusion In Gas Gravity Currents, Jeremy Jac Herman Dec 2013

An Experimental And Computational Evaluation Of The Importance Of Molecular Diffusion In Gas Gravity Currents, Jeremy Jac Herman

Graduate Theses and Dissertations

The accidental release of hazardous, denser-than-air gases during their transport or manufacture is a vital area of study for process safety researchers. This project examines the importance of molecular diffusion on the developing concentration field of a gas gravity current released into a calm environment. Questions which arose from the unexpectedly severe explosion in 2005 at Buncefield, England were of particular interest. The accidental overfilling of a large tank with gasoline on a completely calm morning led to a massive open air explosion. Forensic evidence showed that at the time of ignition, a vapor cloud, most of which now appears …


The Confounding Effects Of Ability, Item Difficulty, And Content Balance Within Multiple Dimensions On The Estimation Of Unidimensional Thetas, Ki Lynn Matlock Aug 2013

The Confounding Effects Of Ability, Item Difficulty, And Content Balance Within Multiple Dimensions On The Estimation Of Unidimensional Thetas, Ki Lynn Matlock

Graduate Theses and Dissertations

When test forms that have equal total test difficulty and number of items vary in difficulty and length within sub-content areas, an examinee's estimated score may vary across equivalent forms, depending on how well his or her true ability in each sub-content area aligns with the difficulty of items and number of items within these areas. Estimating ability using unidimensional methods for multidimensional data has been studied for decades, focusing primarily on subgroups of the population based on the estimated ability for a single set of data (Ackerman, 1987a, 1989; Ansley & Forsyth, 1985; Kroopnick, 2010; Reckase, Ackerman, & Spray, …


Effects Of Ergot Alkaloids And Bovine Bodily Fluids On Cytochrome P450 Activity, Nicholas Scott Ezell May 2013

Effects Of Ergot Alkaloids And Bovine Bodily Fluids On Cytochrome P450 Activity, Nicholas Scott Ezell

Graduate Theses and Dissertations

This thesis evaluates the PromegaTM P450-Glo assay (PromegaTM V9800) as a tool for quantifying ergot alkaloid concentration. Current techniques used for detection of ergot alkaloids are slow and expensive, do not detect all ergot alkaloids, or are not effective on bovine bodily fluids. The first study was conducted to determine effects of commercial ergot alkaloids (n = 6; 0 - 400 μM) on the PromegaTM P450-Glo assay. Cytochrome P450 (CYP450) activity in assay had a differential response to each ergot alkaloid and concentration. As concentrations of ergotamine, dihydroergotamine, ergocornine, and ergocryptine increased CYP450 activity was inhibited (P …