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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
The Differential Effects Of Genetic And Dietary Alterations In Folate Status On Prefrontal Cortical Functions, Jessica Amanda Ash
The Differential Effects Of Genetic And Dietary Alterations In Folate Status On Prefrontal Cortical Functions, Jessica Amanda Ash
Legacy Theses & Dissertations (2009 - 2024)
Folate status plays an essential role in embryogenesis and brain development; however, its importance in supporting cognitive functioning throughout adulthood is less clear. The present study was interested in examining the effects of genetic and dietary alterations in folate status on prefrontal cortical functions in mice, modeling a common polymorphism in the MTHFD1 gene in folate metabolism. A factorial design was used crossing two genotypes (mice with a gene trap insertion in the Mthfd1 gene exhibiting 50% decreased Mthfd1 expression: Mthfd1gt/+ mice or wildtype mice) with two levels of dietary folate (folate sufficient or folate deficient). The mice were tested …
Pcbs And Measures Of Attention And Impulsivity On A Continuous Performance Task Of Young Mohawk Adults, Bita Behforooz
Pcbs And Measures Of Attention And Impulsivity On A Continuous Performance Task Of Young Mohawk Adults, Bita Behforooz
Legacy Theses & Dissertations (2009 - 2024)
Past animal and human studies have shown that exposure to PCBs can result in a wide range of negative toxic effects. However, only a few studies have investigated the relationship between PCB exposure and attention and impulsivity. The present study examined the relationship between current body burden levels of PCBs and attention and impulsivity in young adults ages 17 to 21 from the Mohawk Nation of Akwesasne. The community is concerned because PCBs from industrial effluent have contaminated the local ecology and entered the Mohawk's food chain. Attention and impulsivity were measured by errors of omission and errors of commission …